-
1
-
-
0015043748
-
Mutation and cancer: Statistical study of r
-
Knudson A G. Mutation and cancer: statistical study of retinoblastoma. Proc Natl Acad Sei USA 197I; 68: 820-823.
-
(1971)
Proc Natl Acad Sei USA
, vol.68
, pp. 820-823
-
-
Knudson, A.G.1
-
2
-
-
0020518746
-
Expression of recessive alleles by chromosomal mechanisms in retinoblastoma
-
Cavenee W K, Dryja T P, Phillips R A et al. Expression of recessive alleles by chromosomal mechanisms in retinoblastoma. Nature 1983; 305:779-784.
-
(1983)
Nature
, vol.305
, pp. 779-784
-
-
Cavenee, W.K.1
Dryja, T.P.2
Phillips, R.A.3
-
3
-
-
0025204548
-
Bcl-2 is an inner mitochondria! membrane protein that blocks programmed cell death
-
Hockenbery D, Nunez G, Millman C, Schreiber R D, Korsemeyer S J. Bcl-2 is an inner mitochondria! membrane protein that blocks programmed cell death. Nature 1990; 348: 334-336.
-
(1990)
Nature
, vol.348
, pp. 334-336
-
-
Hockenbery, D.1
Nunez, G.2
Millman, C.3
Schreiber, R.D.4
Korsemeyer, S.J.5
-
4
-
-
0031034563
-
Controlling cell death
-
Golstein P. Controlling cell death. Science 1997; 275: 1081-1082.
-
(1997)
Science
, vol.275
, pp. 1081-1082
-
-
Golstein, P.1
-
5
-
-
0028815546
-
Telomerase activity in preneoplastic and neoplastic gastric and neoplastic gastric and colorectal lesions
-
Tahara H, Kuniyasu H, Yokozaki H et al. Telomerase activity in preneoplastic and neoplastic gastric and neoplastic gastric and colorectal lesions. Clin Cancer Res 1995; 1: 1245-1251.
-
(1995)
Clin Cancer Res
, vol.1
, pp. 1245-1251
-
-
Tahara, H.1
Kuniyasu, H.2
Yokozaki, H.3
-
6
-
-
0030030036
-
Increased expression of cyclin Dl is an early event in multistage colorectal carcinogenesis
-
Arber N, Hibshoosh H, Moss S et al. Increased expression of cyclin Dl is an early event in multistage colorectal carcinogenesis. Gastroenterology 1996; 110: 669-674.
-
(1996)
Gastroenterology
, vol.110
, pp. 669-674
-
-
Arber, N.1
Hibshoosh, H.2
Moss, S.3
-
7
-
-
0030609861
-
Bypass of senescence after disruption of p21 CIP1AVAF1 gene in normal diploid human fibroblasts
-
Brown J P, Wei W, Sedivy J M. Bypass of senescence after disruption of p21 CIP1AVAF1 gene in normal diploid human fibroblasts. Science 1997; 277: 831-834.
-
(1997)
Science
, vol.277
, pp. 831-834
-
-
Brown, J.P.1
Wei, W.2
Sedivy, J.M.3
-
8
-
-
0023937268
-
Evidence for a novel gene associated with low tumor metastatic potential
-
Steeg P S, Bevilacqua G, Kopper L et al. Evidence for a novel gene associated with low tumor metastatic potential. J Natl Cancer Inst 1988; 80: 200-204.
-
(1988)
J Natl Cancer Inst
, vol.80
, pp. 200-204
-
-
Steeg, P.S.1
Bevilacqua, G.2
Kopper, L.3
-
9
-
-
0026666626
-
Participation in normal immune responses of a metastasis-inducing splice variant of CD44
-
Arch R, Wirth K, Hofmann M et al. Participation in normal immune responses of a metastasis-inducing splice variant of CD44. Science 1992; 257: 682-687.
-
(1992)
Science
, vol.257
, pp. 682-687
-
-
Arch, R.1
Wirth, K.2
Hofmann, M.3
-
10
-
-
0026558770
-
Epidemiology of familial adenomatous polyposis in Finland: Impact of family screening on the colorectal cancer rate and survival
-
Jarvinen H J. Epidemiology of familial adenomatous polyposis in Finland: impact of family screening on the colorectal cancer rate and survival. Gut 1992; 33: 353-360.
-
(1992)
Gut
, vol.33
, pp. 353-360
-
-
Jarvinen, H.J.1
-
11
-
-
0023223410
-
Localization of the gene for familial adenomatous polyposis on chromosome 5
-
Bodmer W F, Bailey C J, Bodmer J et al. Localization of the gene for familial adenomatous polyposis on chromosome 5. Nature 1987; 328: 1411-1413.
-
(1987)
Nature
, vol.328
, pp. 1411-1413
-
-
Bodmer, W.F.1
Bailey, C.J.2
Bodmer, J.3
-
12
-
-
0025938038
-
Identification and characterization of the familial adenomatous polyposis coli gene
-
Groden J, Thliveris A, Samowitz W et al. Identification and characterization of the familial adenomatous polyposis coli gene. Cell 1991; 66:589-600.
-
(1991)
Cell
, vol.66
, pp. 589-600
-
-
Groden, J.1
Thliveris, A.2
Samowitz, W.3
-
13
-
-
0026664339
-
Linkage of a variant or attenuated form of adenomatous polyposis coli to the adenomatous polyposis coli (APC) locus
-
Spirio L, Otterud B, Stauffer D et al. Linkage of a variant or attenuated form of adenomatous polyposis coli to the adenomatous polyposis coli (APC) locus. Am J Hum Genet 1992:51:92-100.
-
(1992)
Am J Hum Genet
, vol.51
, pp. 92-100
-
-
Spirio, L.1
Otterud, B.2
Stauffer, D.3
-
14
-
-
16944365288
-
Familial colorectal cancer in Ashkenazim due to a hypermutable tract in APC
-
Laken S J, Petersen G M, Gruber S B et al. Familial colorectal cancer in Ashkenazim due to a hypermutable tract in APC. Nat Genet 1997; 17: 79-83.
-
(1997)
Nat Genet
, vol.17
, pp. 79-83
-
-
Laken, S.J.P.1
-
15
-
-
0029664368
-
Binding of GSK3 to the APC-Catenin complex and regulation of complex assembly
-
Rubinfeld B, Albert I, Porfiri E, Fiol C, Munemitsu S, Polakis P. Binding of GSK3 to the APC-Catenin complex and regulation of complex assembly. Science 1996; 272: 1023-1026.
-
(1996)
Science
, vol.272
, pp. 1023-1026
-
-
Rubinfeld, B.1
Albert, I.2
Porfiri, E.3
Fiol, C.4
Munemitsu, S.5
Polakis, P.6
-
16
-
-
0030944065
-
B-Catenin as oncogene: The smoking gun
-
Peifer M.B-Catenin as oncogene: the smoking gun. Science 1997; 275: 1752-1753.
-
(1997)
Science
, vol.275
, pp. 1752-1753
-
-
Peifer, M.1
-
17
-
-
0030975671
-
Constitutive transcriptional activation by a -catenin-tcf complex in APC7 colon carcinoma
-
Korinek V, Barker N, Morin P J et al. Constitutive transcriptional activation by a -catenin-tcf complex in APC7 colon carcinoma. Science 1997; 275: 1784-1787.
-
(1997)
Science
, vol.275
, pp. 1784-1787
-
-
Korinek, V.1
Barker, N.2
Morin, P.J.3
-
18
-
-
0030949463
-
Activation of -catenintcf signalling in colon cancer by mutations in -catenin or APC
-
Morin P J, Sparks A B, Korinek V et al. Activation of -catenintcf signalling in colon cancer by mutations in -catenin or APC. Science 1997; 275: 1787-1790.
-
(1997)
Science
, vol.275
, pp. 1787-1790
-
-
Morin, P.J.1
Sparks, A.B.2
Korinek, V.3
-
19
-
-
0030900696
-
Stabilization of -catenin by gen
-
Rubinfeld B, Robbins P, El-Gamil M, Albert I, Porfiri E, Polakis P. Stabilization of -catenin by genetic defects in melanoma cell lines. Science 1997; 275: 1790-1793.
-
(1997)
Science
, vol.275
, pp. 1790-1793
-
-
Rubinfeld, B.1
Robbins, P.2
El-Gamil, M.3
Albert, I.4
Porfiri, E.5
Polakis, P.6
-
20
-
-
9044224393
-
Evidence for the involvement of the Wnt 2 gene in human colorectal cancer
-
Vider B Z, Zimber A, Chastre E et al. Evidence for the involvement of the Wnt 2 gene in human colorectal cancer. Oncogene 1996; 12: 153-158.
-
(1996)
Oncogene
, vol.12
, pp. 153-158
-
-
Vider, B.Z.1
Zimber, A.2
Chastre, E.3
-
21
-
-
0027991585
-
Wild-type but not mutant APC associates with the microtubule cytoskel
-
Smith K J, Levy D B, Maupin P, Pollard T D, Vogelstein B, Kanzler K W. Wild-type but not mutant APC associates with the microtubule cytoskeleton. Cancer Res 1994; 54: 3672-3675.
-
(1994)
Cancer Res
, vol.54
, pp. 3672-3675
-
-
Smith, K.J.1
Levy, D.B.2
Maupin, P.3
Pollard, T.D.4
Vogelstein, B.5
Kanzler, K.W.6
-
22
-
-
0027930066
-
The APC gene product associates with microtubules in vivo and promotes their assembly in vitro
-
Munemitsu S, Souza B, Muller O, Albert I, Rubinfeld B, Polakis P. The APC gene product associates with microtubules in vivo and promotes their assembly in vitro. Cancer Res 1994; 54:3676-3681.
-
(1994)
Cancer Res
, vol.54
, pp. 3676-3681
-
-
Munemitsu, S.1
Souza, B.2
Muller, O.3
Albert, I.4
Rubinfeld, B.5
Polakis, P.6
-
23
-
-
0026744757
-
Colon cancer genetics
-
Lynch H T, Watson P, Smyrk T C et al. Colon cancer genetics. Cancer 1992; 70(5 Suppl): 1300-1312.
-
(1992)
Cancer
, vol.70
, pp. 1300-1312
-
-
Lynch, H.T.1
Watson, P.2
Smyrk, T.C.3
-
25
-
-
0027263363
-
Genetic mapping of a locus predisposing to Human Colorectal Cancer
-
Peltomaki P, Aaltonen L A, Sistonen P et al. Genetic mapping of a locus predisposing to Human Colorectal Cancer. Science 1993; 260: 810-812.
-
(1993)
Science
, vol.260
, pp. 810-812
-
-
Peltomaki, P.1
Aaltonen, L.A.2
Sistonen, P.3
-
26
-
-
0027158031
-
Clues to the pathogenesis of Familial Colorectal Cancer
-
Aaltonen L A, Peltomaki P, Leach F S et al. Clues to the pathogenesis of Familial Colorectal Cancer. Science 1993; 260:812-816.
-
(1993)
Science
, vol.260
, pp. 812-816
-
-
Aaltonen, L.A.1
Peltomaki, P.2
Leach, F.S.3
-
27
-
-
0027314411
-
Microsatellite instability in the proximal colon
-
Thibodeau S N, Bren G, Schaid D. Microsatellite instability in the proximal colon. Science 1993; 260: 816-819.
-
(1993)
Science
, vol.260
, pp. 816-819
-
-
Thibodeau, S.N.1
Bren, G.2
Schaid, D.3
-
28
-
-
0028845919
-
DMA mismatch repair and cancer
-
Chung D C, Rustgi A K. DMA mismatch repair and cancer. Gastroenterology 1995; 109: 1685-1699.
-
(1995)
Gastroenterology
, vol.109
, pp. 1685-1699
-
-
Chung, D.C.1
Rustgi, A.K.2
-
29
-
-
0027742295
-
The human mutator gene homolog MSH2 and its association with Hereditary Nonpolyposis Colon Cancer
-
Fishel R, Lescoe M K, Rao M R S et al. The human mutator gene homolog MSH2 and its association with Hereditary Nonpolyposis Colon Cancer. Cell 1993; 75: 1027-1038.
-
(1993)
Cell
, vol.75
, pp. 1027-1038
-
-
Fishel, R.1
Lescoe, M.K.2
Rao, M.R.S.3
-
30
-
-
0027145633
-
Mutations of a MutS homolog in Hereditary Non-Polyposis Colorectal Cancer
-
Leach F S, Nicolaides N C, Papadopoulos N et al. Mutations of a MutS homolog in Hereditary Non-Polyposis Colorectal Cancer. Cell 1993; 75: 1215-1225.
-
(1993)
Cell
, vol.75
, pp. 1215-1225
-
-
Leach, F.S.1
Nicolaides, N.C.2
Papadopoulos, N.3
-
31
-
-
0028221943
-
Mutation in thé DNA mismatch repair gene homologue hMLHl is associated with Hereditary Non-Polyposis Colon Cancer
-
Bronner C E, Baker S M, Morrison P T et al. Mutation in thé DNA mismatch repair gene homologue hMLHl is associated with Hereditary Non-Polyposis Colon Cancer. Nature 1994; 368:258-261.
-
(1994)
Nature
, vol.368
, pp. 258-261
-
-
Bronner, C.E.1
Baker, S.M.2
Morrison, P.T.3
-
32
-
-
0028350601
-
Mutation of a mutL homolog in Hereditary Colon Cancer
-
Papadopoulos N, Nicolaides N, Wei Y F et al. Mutation of a mutL homolog in Hereditary Colon Cancer. Science 1994; 263: 1625-1628.
-
(1994)
Science
, vol.263
, pp. 1625-1628
-
-
Papadopoulos, N.1
Nicolaides, N.2
Wei, Y.F.3
-
33
-
-
0027933070
-
Mutations of two PMS homologues in Hereditary NonPolyposis Colon Cancer
-
Nicolaides N C, Papadopoulos N, Liu B et al. Mutations of two PMS homologues in Hereditary NonPolyposis Colon Cancer. Nature 1994; 371: 75-80.
-
(1994)
Nature
, vol.371
, pp. 75-80
-
-
Nicolaides, N.C.1
Papadopoulos, N.2
Liu, B.3
-
34
-
-
0029838771
-
Expression of human MutS homolog 2 (hMSH2) protein in resting and proliferating cells
-
Marra G, Chang C L, Laghi L A, Chauhan D P, Young D, Boland C R. Expression of human MutS homolog 2 (hMSH2) protein in resting and proliferating cells. Oncogene 1996; 13:2189-2196.
-
(1996)
Oncogene
, vol.13
, pp. 2189-2196
-
-
Marra, G.1
Chang, C.L.2
Laghi, L.A.3
Chauhan, D.P.4
Young, D.5
Boland, C.R.6
-
35
-
-
2942569549
-
Analysis of mismatch repair genes in Hereditary Non-Polyposis Colorectal Cancer patients
-
Liu B, Parsons R, Papadopoulos N et al. Analysis of mismatch repair genes in Hereditary Non-Polyposis Colorectal Cancer patients. Nat Med 1996; 2: 169-174.
-
(1996)
Nat Med
, vol.2
, pp. 169-174
-
-
Liu, B.1
Parsons, R.2
Papadopoulos, N.3
-
36
-
-
0028859670
-
Polymerase ô variants in RER colorectal tumours
-
da Costa L T, Wafik E D, Hamilton S R et al. Polymerase ô variants in RER colorectal tumours. Nat Genet 1995; 9: 10-11.
-
(1995)
Nat Genet
, vol.9
, pp. 10-11
-
-
Costa, L.T.1
Wafik, E.D.2
Hamilton, S.R.3
-
37
-
-
0030054532
-
Molecular nature of colon tumours in Hereditary Nonpolyposis Colon Cancer, Familial Polyposis, and Sporadic Colon Cancer
-
Konishi M, Kikuchi-Yanoshita R, Tanaka K et al. Molecular nature of colon tumours in Hereditary Nonpolyposis Colon Cancer, Familial Polyposis, and Sporadic Colon Cancer. Gastroenterology 1996; 111:307-317.
-
(1996)
Gastroenterology
, vol.111
, pp. 307-317
-
-
Konishi, M.1
Kikuchi-Yanoshita, R.2
Tanaka, K.3
-
38
-
-
0031018674
-
Somatic frameshift mutations in the BAX gene in colon cancer of the mutator phenotype
-
Rampino N, Yamamoto H, lonov Y et al. Somatic frameshift mutations in the BAX gene in colon cancer of the mutator phenotype. Science 1997; 275: 967-969.
-
(1997)
Science
, vol.275
, pp. 967-969
-
-
Rampino, N.1
Yamamoto, H.2
Lonov, Y.3
-
39
-
-
0030061148
-
Better survival rates in patients with MLH1-associated hereditary colorectal cancer
-
Sankila R, Aaltonen L A, Jarvinen H J, Mecklin J-P. Better survival rates in patients with MLH1-Associated Hereditary Colorectal Cancer. Gastroenterology 1996; 110: 682-687.
-
(1996)
Gastroenterology
, vol.110
, pp. 682-687
-
-
Sankila, R.1
Aaltonen, L.A.2
Jarvinen, H.J.3
Mecklin, J.-P.4
-
40
-
-
0030065387
-
Colorectal cancer, survival advantage, and Hereditary Non-Polyposis Colorectal Carcinoma
-
Lynch HT, Smyrik T. Colorectal cancer, survival advantage, and Hereditary Non-Polyposis Colorectal Carcinoma. Gastroenterology 1996; 110:943-954.
-
(1996)
Gastroenterology
, vol.110
, pp. 943-954
-
-
Lynch, H.T.1
Smyrik, T.2
-
41
-
-
0031012344
-
Localization of a susceptibility locus for Peutz-Jeghers syndrome to 19p using comparative genomic hybridization and targeted linkage analysis
-
Hemminki A, Tomlinson I, Markie D et al. Localization of a susceptibility locus for Peutz-Jeghers syndrome to 19p using comparative genomic hybridization and targeted linkage analysis. Nat Genet 1997; 15:87-90.
-
(1997)
Nat Genet
, vol.15
, pp. 87-90
-
-
Hemminki, A.1
Tomlinson, I.2
Markie, D.3
-
42
-
-
0031049128
-
Genetic alterations and epithelial dysplasia in juvenile polyposis syndrome and sporadic juvenile polyps
-
Wu T, Rezai B, Rashid A et al. Genetic alterations and epithelial dysplasia in juvenile polyposis syndrome and sporadic juvenile polyps. Am J Pathol 1997; 150: 939-946.
-
(1997)
Am J Pathol
, vol.150
, pp. 939-946
-
-
Wu, T.1
Rezai, B.2
Rashid, A.3
-
43
-
-
0025312728
-
A gen
-
Fearon E R, Vogelstein B. A genetic model for colorectal tumorigenesis. Cell 1990; 61: 759-767.
-
(1990)
Cell
, vol.61
, pp. 759-767
-
-
Fearon, E.R.1
Vogelstein, B.2
-
44
-
-
0026630266
-
APC mutations occur early during colorectal tumorigenesis
-
Powell S M, Zilz N, Beazer-Barclay Y et al. APC mutations occur early during colorectal tumorigenesis. Nature 1992; 359: 235-237.
-
(1992)
Nature
, vol.359
, pp. 235-237
-
-
Powell, S.M.1
Zilz, N.2
Beazer-Barclay, Y.3
-
45
-
-
0028062973
-
Somatic APC and K-ras codon 12 mutations in aberrant crypt foci from human colons
-
Smith A J, Stern H S, Penner M et al. Somatic APC and K-ras codon 12 mutations in aberrant crypt foci from human colons. Cancer Res 1994; 54:5527-5530.
-
(1994)
Cancer Res
, vol.54
, pp. 5527-5530
-
-
Smith, A.J.1
Stern, H.S.2
Penner, M.3
-
46
-
-
0028897398
-
Frequent and characteristic K-ras activation and absence of p53 protein accumulation in aberrant crypt foci of the colon
-
Yamashita N, Minamoto T, Ochiai A, Onda M, Esumi H. Frequent and characteristic K-ras activation and absence of p53 protein accumulation in aberrant crypt foci of the colon. Gastroenterology 1995; 108:434-440.
-
(1995)
Gastroenterology
, vol.108
, pp. 434-440
-
-
Yamashita, N.1
Minamoto, T.2
Ochiai, A.3
Onda, M.4
Esumi, H.5
-
47
-
-
0027973077
-
Molecular determinants of dysplasia in colorectal lesions
-
Jen J, Powell S M, Papadopoulos N et al. Molecular determinants of dysplasia in colorectal lesions. Cancer Res 1994; 54: 5523-5526.
-
(1994)
Cancer Res
, vol.54
, pp. 5523-5526
-
-
Jen, J.1
Powell, S.M.2
Papadopoulos, N.3
-
48
-
-
0342819718
-
Mutations in the KRAS2 oncogene during progressive stages of human colon carcinoma
-
Buriner G C, Loeb L A. Mutations in the KRAS2 oncogene during progressive stages of human colon carcinoma. Proc Natl Acad Sei USA 1989: 86: 2403-2407.
-
(1989)
Proc Natl Acad Sei USA
, vol.86
, pp. 2403-2407
-
-
Buriner, G.C.1
Loeb, L.A.2
-
49
-
-
0029869360
-
Evidence for reciprocity of bcl-2 and p53 expression in human colorectal adenomas and carcinomas
-
Watson A J M, Merritt A J, Jones L S et al. Evidence for reciprocity of bcl-2 and p53 expression in human colorectal adenomas and carcinomas. Br J Cancer 1996; 73: 889-895.
-
(1996)
Br J Cancer
, vol.73
, pp. 889-895
-
-
Watson, A.J.M.1
Merritt, A.J.2
Jones, L.S.3
-
50
-
-
0029013631
-
Telomerase activity associated with the acquisition of malignancy in human colorectal cancer
-
Chadeneau C, Kazy H, Hirte H W, Gallinger S, Bacchetti S. Telomerase activity associated with the acquisition of malignancy in human colorectal cancer. Cancer Res 1995; 55: 2533-2536.
-
(1995)
Cancer Res
, vol.55
, pp. 2533-2536
-
-
Chadeneau, C.1
Kazy, H.2
Hirte, H.W.3
Gallinger, S.4
Bacch5
-
51
-
-
0027993458
-
Up-regulation of cyclooxygenase 2 gene expression in human colorectal adenomas and adenocarcinomas
-
Eberhart C E, Coffey R J, Radhika A et al. Up-regulation of cyclooxygenase 2 gene expression in human colorectal adenomas and adenocarcinomas. Gastroenterology 1994; 107: 1183-1188.
-
(1994)
Gastroenterology
, vol.107
, pp. 1183-1188
-
-
Eberhart, C.E.1
Coffey, R.J.2
Radhika, A.3
-
52
-
-
0025056930
-
Identification of a chromosome 18q gene that is altered in colorectal cancer
-
Fearon E R, Cho K R, Nigro J M et al. Identification of a chromosome 18q gene that is altered in colorectal cancer. Science 1990; 247: 49-56.
-
(1990)
Science
, vol.247
, pp. 49-56
-
-
Fearon, E.R.1
Cho, K.R.2
Nigro, J.M.3
-
53
-
-
0030943272
-
Putative cancer gene shows up in development instead
-
Roush W. Putative cancer gene shows up in development instead. Science 1997; 276:534-535.
-
(1997)
Science
, vol.276
, pp. 534-535
-
-
Roush, W.1
-
54
-
-
0030995125
-
Phenotype of mice lacking functional deleted in colorectal cancer (Dec) gene
-
Fazeli A, Dickinson S L, Hermiston M L et al. Phenotype of mice lacking functional deleted in colorectal cancer (Dec) gene. Nature 1997; 386: 796-804.
-
(1997)
Nature
, vol.386
, pp. 796-804
-
-
Fazeli, A.1
Dickinson, S.L.2
Hermiston, M.L.3
-
56
-
-
0025980976
-
Suppression of tumorigenicity in human colon carcinoma cell lines by introduction of normal chromosome 5 or 18
-
Tanaka K, Oshimura M, Kikachi R et al. Suppression of tumorigenicity in human colon carcinoma cell lines by introduction of normal chromosome 5 or 18. Nature 1991; 349: 340-342.
-
(1991)
Nature
, vol.349
, pp. 340-342
-
-
Tanaka, K.1
Oshimura, M.2
Kikachi, R.3
-
57
-
-
0025634118
-
-
Baker S J, Preisinger A C, Jessup J M et al. p53 gene mutations occur in combination with 17p allelic deletions as late events in colorectal tumorigenesis. Cancer Res 1990; 50: 7717-7722.
-
(1990)
Cancer Res
, vol.50
, pp. 7717-7722
-
-
Baker, S.J.1
Preisinger, A.C.2
Jessup, J.M.3
-
58
-
-
0027210981
-
Gain of function mutations in p53
-
Dittmer D, Pâti S, Zambetti G et al. Gain of function mutations in p53. Nat Genet 1993; 4:42-46.
-
(1993)
Nat Genet
, vol.4
, pp. 42-46
-
-
Dittmer, D.1
Pâti, S.2
Zamb3
-
59
-
-
0027109075
-
Guardian of the genome
-
Lane D P. p53, guardian of the genome. Nature 1992; 358: 15-16.
-
(1992)
Nature
, vol.358
, pp. 15-16
-
-
-
60
-
-
0025221248
-
Human colorectal cancer: High frequency of deletions at chromosome Ip35
-
Leister I, Weith A, Bruderlein S et al. Human colorectal cancer: high frequency of deletions at chromosome Ip35. Cancer Res 1990; 50: 7232-7235.
-
(1990)
Cancer Res
, vol.50
, pp. 7232-7235
-
-
Leister, I.1
Weith, A.2
Bruderlein, S.3
-
61
-
-
0026546190
-
Survival and acquired genetic alterations in colorectal cancer
-
Laurent-Puig P, Olschwang S, Delattre O et al. Survival and acquired genetic alterations in colorectal cancer. Gastroenterology 1992; 102: 1136-1141.
-
(1992)
Gastroenterology
, vol.102
, pp. 1136-1141
-
-
Laurent-Puig, P.1
Olschwang, S.2
Delattre, O.3
-
62
-
-
0028230304
-
Del
-
Yaremko M L, Wasylyshyn M L, Paulus K L, Michelassi F, Westbrook C A. Deletion mapping reveals two regions of chromosome 8 allele loss in colorectal carcinoma. Genes Chromosomes Cancer 1994; 10: 1-6.
-
(1994)
Genes Chromosomes Cancer
, vol.10
, pp. 1-6
-
-
Yaremko, M.L.1
Wasylyshyn, M.L.2
Paulus, K.L.3
Michelassi, F.4
Westbrook, C.A.5
-
63
-
-
0028354948
-
A 3-Mb physical map of the chromosome region 8p21. 3-p22, including a 600-kb region commonly deleted in human hepatocellular carcinoma, colorectal cancer and non-small cell lung cancer
-
Fujiwara Y, Ohata H, Emi M et al. A 3-Mb physical map of the chromosome region 8p21. 3-p22, including a 600-kb region commonly deleted in human hepatocellular carcinoma, colorectal cancer and non-small cell lung cancer. Genes Chromosomes Cancer 1994; 10: 7-14.
-
(1994)
Genes Chromosomes Cancer
, vol.10
, pp. 7-14
-
-
Fujiwara, Y.1
Ohata, H.2
Emi, M.3
-
65
-
-
0027419340
-
Frequent loss of heterozygosity on chromosome 14 occurs in advanced colorectal carcinomas
-
Young J, Leggett B, Ward M et al. Frequent loss of heterozygosity on chromosome 14 occurs in advanced colorectal carcinomas. Oncogene 1993; 8: 671-675.
-
(1993)
Oncogene
, vol.8
, pp. 671-675
-
-
Legg, Y.J.1
-
66
-
-
0027973944
-
Frequency of allele loss of DCC, p53, RB1, WT1, NF1, NM23 and APCA1CC in colorectal cancer assayed by fluorescent multiplex polymerase chain reaction
-
Cawkwell L, Lewis F A , Quirke P. Frequency of allele loss of DCC, p53, RB1, WT1, NF1, NM23 and APCA1CC in colorectal cancer assayed by fluorescent multiplex polymerase chain reaction. Br J Cancer 1994; 70: 813-818.
-
(1994)
Br J Cancer
, vol.70
, pp. 813-818
-
-
Cawkwell, L.1
Lewis, F.A.2
Quirke, P.3
-
67
-
-
0022506980
-
A human DNA segment with properties of the gene that predisposes to human retinoblastoma and osteosarcoma
-
Friend S H, Bernards R, Rogeli S et al. A human DNA segment with properties of the gene that predisposes to human retinoblastoma and osteosarcoma. Nature 1986; 323: 643-646.
-
(1986)
Nature
, vol.323
, pp. 643-646
-
-
Friend, S.H.1
Bernards, R.2
Rogeli, S.3
-
69
-
-
0027158031
-
Clues to the pathogenesis of familial colorectal cancer
-
Aaltonen L A, Peltomaki P, Leach F S et al. Clues to the pathogenesis of familial colorectal cancer. Science 1993; 260:812-816.
-
(1993)
Science
, vol.260
, pp. 812-816
-
-
Aaltonen, L.A.1
Peltomaki, P.2
Leach, F.S.3
-
70
-
-
0027314411
-
Microsatellite instability in cancer of the proximal colon
-
Thibodeau S N, Bren G, Schaid D. Microsatellite instability in cancer of the proximal colon. Science 1993; 260: 816-819.
-
(1993)
Science
, vol.260
, pp. 816-819
-
-
Thibodeau, S.N.1
Bren, G.2
Schaid, D.3
-
71
-
-
0029166645
-
Microsatellite instability in colorectal cancer: Improved assessment using fluorescent polymerase chaim reaction
-
Cawkwell L, Li D, Lewis F A et al. Microsatellite instability in colorectal cancer: improved assessment using fluorescent polymerase chaim reaction. Gastrocnterology 1995; 109:465-471.
-
(1995)
Gastrocnterology
, vol.109
, pp. 465-471
-
-
Cawkwell, L.1
Li, D.2
Lewis, F.A.3
-
72
-
-
0028276666
-
Clinical and pathological characteristics of sporadic colorectal carcinomas with DNA replication errors in microsatellite sequences
-
Kirn H, Jen J, Vogelstein B, Hamilton S R. Clinical and pathological characteristics of sporadic colorectal carcinomas with DNA replication errors in microsatellite sequences. Am J Pathol 1994; 145: 148-156.
-
(1994)
Am J Pathol
, vol.145
, pp. 148-156
-
-
Kirn, H.1
Jen, J.2
Vogelstein, B.3
Hamilton, S.R.4
-
73
-
-
0029991682
-
Microsatellite instability and the role of HMSH2 in sporadic colorectal cancer
-
Bubb V J, Curtis L C, Cunningham C et al. Microsatellite instability and the role of HMSH2 in sporadic colorectal cancer. Oncogene 1996; 12: 2641-2649.
-
(1996)
Oncogene
, vol.12
, pp. 2641-2649
-
-
Bubb, V.J.1
Curtis, L.C.2
Cunningham, C.3
-
74
-
-
0028859671
-
Mismatch repair gene defects in sporadic colorectal cancer with microsatellite instability
-
Liu B, Nicolaides N, Markowitz S et al. Mismatch repair gene defects in sporadic colorectal cancer with microsatellite instability. Nat Genet 1995; 9:48-55.
-
(1995)
Nat Genet
, vol.9
, pp. 48-55
-
-
Liu, B.1
Nicolaides, N.2
Markowitz, S.3
-
75
-
-
0030971878
-
Microsatellite instability in colorectal adenomas
-
Samowitz W S, Slattery M L. Microsatellite instability in colorectal adenomas. Gastroenterology 1997; 112: 1515-1519.
-
(1997)
Gastroenterology
, vol.112
, pp. 1515-1519
-
-
Samowitz, W.S.1
Slattery, M.L.2
-
76
-
-
0030062916
-
Flat adenoma as a precursor of colorectal carcinoma in Hereditary Non-Polyposis Colorectal Carcinoma
-
Watanable T, Muto R, Sawada T et al. Flat adenoma as a precursor of colorectal carcinoma in Hereditary Non-Polyposis Colorectal Carcinoma. Cancer 1996; 77: 627-634.
-
(1996)
Cancer
, vol.77
, pp. 627-634
-
-
Watanable, T.1
Muto, R.2
Sawada, T.3
-
77
-
-
0026574906
-
Loss of heterozygosity affecting the p53, Rb, and MCC/APC tumor suppressor gene loci in dysplastic and cancerous ulcerative colitis
-
Greenwald B D, Harpaz N, Yin J et al. Loss of heterozygosity affecting the p53, Rb, and MCC/APC tumor suppressor gene loci in dysplastic and cancerous ulcerative colitis. Cancer Res 1992; 52: 741-745.
-
(1992)
Cancer Res
, vol.52
, pp. 741-745
-
-
Greenwald, B.D.1
Harpaz, N.2
Yin, J.3
-
78
-
-
0027956082
-
Molecular genetic profiles of colitis-associated neoplasms
-
Kern S E, Redstone M, Seymour A B et al. Molecular genetic profiles of colitis-associated neoplasms. Gastroenterology 1994; 107: 420-428.
-
(1994)
Gastroenterology
, vol.107
, pp. 420-428
-
-
Kern, S.E.1
Redstone, M.2
Seymour, A.B.3
-
79
-
-
0028067504
-
Microsatellite instability in ulcerative-colitis associated dysplasias and cancers
-
Suzuki H, Harpaz N, Tannin Y et al. Microsatellite instability in ulcerative-colitis associated dysplasias and cancers. Cancer Res 1994; 54:4841-4844.
-
(1994)
Cancer Res
, vol.54
, pp. 4841-4844
-
-
Suzuki, H.1
Harpaz, N.2
Tannin, Y.3
-
80
-
-
0027194679
-
-
Yin J, Harpaz N, Tong Y et al. p53 point mutations in dysplastic and cancerous ulcerative colitis lesions. Gastroenterology 1993; 104: 1633-1639.
-
(1993)
Gastroenterology
, vol.104
, pp. 1633-1639
-
-
Yin, J.1
Harpaz, N.2
Tong, Y.3
-
81
-
-
0030895555
-
DCC expression and prognosis in colorectal cancer
-
Banerjee A K. DCC expression and prognosis in colorectal cancer. Lancet 1997; 349: 968.
-
(1997)
Lanc
, vol.349
, pp. 968
-
-
Banerjee, A.K.1
-
82
-
-
0029955460
-
The DCC protein and prosnosis in colorectal cancer
-
Shibata D, Reale M A, Lavin P et al. The DCC protein and prosnosis in colorectal cancer. N Engl J Med 1996; 335: 1727-1732.
-
(1996)
N Engl J Med
, vol.335
, pp. 1727-1732
-
-
Shibata, D.1
Reale, M.A.2
Lavin, P.3
-
83
-
-
0028927179
-
P53, cell cycle control and apoptosis: Implications for cancer
-
Kastan M B, Canman C E, Leonard C J. P53, cell cycle control and apoptosis: implications for cancer. Cancer Metastasis Rev 1995; 14:3-15.
-
(1995)
Cancer M
, vol.14
, pp. 3-15
-
-
Kastan, M.B.1
Canman, C.E.2
Leonard, C.J.3
-
84
-
-
0029961006
-
Telomerase activity is commonly d
-
Li Z H, Salovaara R, Aaltonen L A, Shibata D. Telomerase activity is commonly detected in Hereditary Nonpolyposis Colorectal Cancers. Am J Pathol 1996; 148: 1075-1078.
-
(1996)
Am J Pathol
, vol.148
, pp. 1075-1078
-
-
Li, Z.H.1
Salovaara, R.2
Aaltonen, L.A.3
Shibata, D.4
-
85
-
-
0038682553
-
Detection of telomerase activity in exfoliated cancer cells in colonie luminal washings and its related clinical implications
-
Yoshida K, Sugino T, Goodison S et al. Detection of telomerase activity in exfoliated cancer cells in colonie luminal washings and its related clinical implications. Br J Cancer 1997; 75: 548-553.
-
(1997)
Br J Cancer
, vol.75
, pp. 548-553
-
-
Yoshida, K.1
Sugino, T.2
Goodison, S.3
-
86
-
-
0026537986
-
Identification of ras oncogene mutations in the stool of patients with curable colorectal tumour
-
Sidransky D, Tokino T, Hamilton S R et al. Identification of ras oncogene mutations in the stool of patients with curable colorectal tumour. Science 1992; 256: 102-105.
-
(1992)
Science
, vol.256
, pp. 102-105
-
-
Sidransky, D.1
Tokino, T.2
Hamilton, S.R.3
-
87
-
-
0029970487
-
Identification of subjects at risk for colorectal carcinoma through a test based on K-ras determination in the stool
-
Villa E, Dugani A, Rebecchi A M et al. Identification of subjects at risk for colorectal carcinoma through a test based on K-ras determination in the stool. Gastroenterology 1996; 110: 1346-1353.
-
(1996)
Gastroenterology
, vol.110
, pp. 1346-1353
-
-
Villa, E.1
Dugani, A.2
Rebecchi, A.M.3
-
88
-
-
0029925246
-
Mutations of the p53 gene in the stool of patients with resectable colorectal cancer
-
Eguchi S, Kohara N, Komuta K, Kanematsu T. Mutations of the p53 gene in the stool of patients with resectable colorectal cancer. Cancer suppl. 1996; 778: 1707-1710.
-
(1996)
Cancer Suppl.
, vol.778
, pp. 1707-1710
-
-
Eguchi, S.1
Kohara, N.2
Komuta, K.3
Kanematsu, T.4
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