Cytokine-induced production of NO by macrophages induces apoptosis and immunological rejection of AK-5 histiocytic tumor

Apoptosis

Volumn 3, Issue 5, 1998, Pages 361-368

  Bhaumik, S ^a   Khar, A ^a  

^a CENTRE FOR CELLULAR AND MOLECULAR BIOLOGY   (India)

Author keywords

Apoptosis; Cytokines; Macrophages; Nitric oxide

Indexed keywords

ANIMALIA;

EID: 0001453995     PISSN: 13608185     EISSN: None     Source Type: Journal    
DOI: 10.1023/A:1009685206353     Document Type: Article

References (45)

1. Manjo G, Joris I. Apoptosis, oncosis and necrosis, an overview of cell death. Am J Path 1995; 146: 13-15.
2. Adams DO, Hamilton TA. The cell biology of macrophage activation. Am Rev Immunol 1984; 2: 283-318.
3. Doharty TM, Kastelein R, Menon S, Andrade S, Coffman RL. Modulation of murine macrophage function by IL-13. J Immunol 1993; 151: 7151-7160.
4. + T cell to enhance priming for interferon γ production and diminishes interleukin 4 inhibition of such priming. Proc Natl Acad Sci USA 1993; 90: 10188-10192.
5. Doherty TM. T-cell regulation of macrophage function. Curr Opin Immunol 1995; 7: 400-404.
6. Ding AH, Nathan CF, Stuehr DJ. Release of reactive nitrogen intermediates and reactive oxygen intermediates from mouse peritoneal macrophages: comparison of activating cytokines and evidence for independent production. J Immunol 1988; 141: 2407-2412.
7. Drapier J-C, Wietzerbin J, Hibbs JB Jr. Interferon γ and tumor necrosis factor induce the Larginin dependent cytotoxic effector mechanism in murine macrophages. Eur J Immunol 18: 1587-1592.
8. Hori K, Ehrke MJ, Mace K, Mihich E. Effect of recombinant tumor necrosis factor on tumoricidal activation of murine macrophages: synergism between tumor necrosis factor and γ-interferon. Cancer Res 1987; 47: 5868-5874.
9. Chen L, Suzuki Y, Wheelock EF. Interferon γ synergyses with tumor necrosis factor and with interleukin 1 and requires the presence of both monokines to induce antitumor cytotoxic activity in macrophages. J Immunol 1987; 139: 4096-4101.
10. McCall TB, Feelisch M, Palmer RMJ, Moncada S. Identification of N-imineothyl-L-omithine as an irreversible inhibitor of nitric oxide synthase in phagocytic cells. Br J Pharmacol 1991a; 102: 234-238.
11. Moncada S, Palmer RMJ, Higgs EA, Nitric oxide: physiology, pathophysiology and pharmacology. Pharmacol Rev 1991; 43: 109-142.
12. Hibbs JB, Taintor RR, Vavrion Z, Rachlin EM. Nitric oxide: a cytotoxic activated macrophage effector molecule. Biochem Biophys Res Commun 1988; 157: 87-94.
13. Stuehr DJ, Nathan CF. Nitric oxide a macrophage product responsible for cytostasis and respiratory inhibition in tumor target cells. J Expt Med 1989; 169: 1543-1555.
14. Cox GW, Mellillo G, Chattopadhyay U, Mullett D, Fertel RH, Varesio L. Tumor necrosis factor-α-dependent production of reactive nitrogen intermediates mediate IFN-γ plus IL-2-induced murine macrophage tumoricidal activity. J Immunol 1992; 149: 3290-3296.
15. Burney S, Tamir S, Gal A, Tannenbaum SR. A mechanistic analysis of nitric oxide-induced cellular toxicity. Nitric Oxide: Bio and Chem 1997; 1: 130-144.
16. Ciu X, Reichner JS, Mateo RB, Albina JE. Activated murine macrophages induce apoptosis in tumor cells through nitric oxide-dependent or independent mechanism. Cancer Res 1994; 54: 2462-2467.
17. Khar A. Development and characterisation of a rat histiocytemacrophage tumor line. J Natl Cancer Inst 1986; 76: 871-878.
18. Khar A. Characterisation of spontaneous immunological regression in a histiocytoma: I Role of NK cell and antitumor antibodies. Int J Onco 1993; 3: 393-398.
19. Bright JJ, Hegde SP, Begum Z, Khar A. Modulation of natural killer cell function leading to spontaneous regression of a histiocytoma. Cell Immunol 1994; 154: 54-65.
20. Khar A, Kumari AL, Ali AM. Characterisation of spontaneous immunological regression in histiocytoma: participation of tumor necrosis factor. Int J Oncol 1993; 2: 399-402.
21. Kausalya S, Hegde SP, Bright JJ, Khar A. Mechanism of antibody-dependent natural killer cell mediated AK-5 tumor cell death. Expt Cell Res 1994; 212: 285-290.
22. Khar A, Pardhasaradhi BVV, Varalakshmi Ch, Ali AM, Kumari AL. Natural killer cell as the effector which mediates in vivo apoptosis in AK-5 tumor cells. Cell Immunol 1997; 177: 86-92.
23. Khar A, Ali AM. Adaptation of rat histiocytoma cells AK-5, to growthin culture. In Vitro Cell Dev Biol 1990; 26: 1024-1025.
24. Bhaumik S, Chattopadhyay S. Effect of shilajit on mouse peritoneal macrophages. Phytothera Res 1993; 7: 425-427.
25. Ijsselmuiden OE, Herbrink P, Meddens MJM, et al. Optimizing the solid-phase immunofiltration assay: a rapid alternative to immunoassay. J Immunol Meth 1989; 119: 35-43.
26. Khar A, Ali AM, Gopalkrishna P, Kumari AL. Purification and characterisation of tumor necrosis factor α with cytotoxic activity against AK-5 cells. Ind J Exp Bio 1993; 31: 922-925.
27. Dietert RR, Hotchkiss JH, Austic RE, Sung Y-J. Production of reactive nitrogen intermediates by macrophages. Meth Immunotoxicol 1995; 2: 99-115.
28. Lewis JG. State of macrophage activation: tumor cell cytolysis. Meth Immunotoxicol 1995; 2: 59-65.
29. Hibbs JB Jr, Taintor RR, Vavrin Z. Macrophage cytotoxicity: role for L-arginine deiminase activity and imino nitrogen oxidation to nitrite. Science 1987a; 235: 473-476.
30. Khar A, Kausalya S, Kamal MA. AK-5 tumor-induced modulation of host immune function: upregulation of Th1-type cytokine response mediates early tumor regression. Cyto Mol Ther 1996; 2: 39-46.
31. Hegde SP, Bright JJ, Kausalya S, Khar A. AK-5 tumor-induced expression of interleukin-12: role of IL-12 in NK-mediated AK-5 regression. Cell Immunol 1995; 162: 241-247.
32. Kausalya S, Varalakshmi C, Khar A. Correlation of in vitro and in vivo effects of interferon-γ with the spontaneous regression of a rat histiocytoma. J Inter Cyto Res 1995; 15: 647-654.
33. Xie K, Wang Y, Huang S, et al. Nitric oxide mediated apoptosis of K-1735 melanoma cells is associated with downregulation of Bcl-2. Oncogenes 1997; 15: 771-779.
34. MacMicking J, Xie Q-W, Nathan C. Nitric oxide and macrophage function. Am Rev Immunol 1997; 15: 323-350.
35. Rao KL, Varalakshmi Ch, Ali AM, Khar A. Administration of anti-IL-12 antibody in vivo inhibits rejection of a rat histiocytoma and suppresses cytokine response in a tumor bearing rat. Immunol 1997; 92: 381-387.
36. Smith SR, Manfra D, Davies L, Terminellic Denhardt G, Donkin J. Elevated level of NO in both unchallenged and LPS challenged C parvum-primed mice are attributable to the activity of a cytokine-inducible isoform of iNOS. J Leuk Biol 1997; 61: 34-32.
37. Oswald IP, Dozois CM, Petit JJ, Lemaire G. Interleukin-12 synthesis is a required step in trehalose dimycolate-induced activation of mouse peritoneal macrophages. Infect Immunol 1997; 65: 1364-1369.
38. Abrahamson IA, Coffman RL. Trypanosoma cruze: IL-10, TNF-α, IFN-γ and IL-12 regulate innate and acquired immunity to infection. Expt Parasitol 1996; 84: 231-244.
39. Natsala CL, Edington HD, McKinney TG, et al. Recombanant interleukin-12 adminstration induces tumor regression in association with IFN-γ production. J Immunol 1994; 153: 1697-1706.
40. Ho YS, Lee HM, Mou TC, Wang YJ, Lin JK. Suppression of nitric oxide induced apoptosis by N-acetyl-L-cysteine through modulation of glutathione, Bcl-2, and bax protein levels. Mol Carcinog 1997; 19: 101-113.
41. Hortelano S, Dallaporta B, Zamzami N, et al. Nitric oxide induces apoptosis via triggering mitochondrial permeability transition. FEBS Lett 1997; 410: 373-377.
42. Kroncke KD, Fehsel K, and Kolb-Bachofen V. Nitric oxide: cytotoxicity versus cytoprotection - how, why, when and where? Nitric Oxide 1997; 1: 107-120.
43. Brockhans F, Briine B. U937 apoptotic cel death by nitric oxide. Bcl-2 downregulation and caspase activation. Exp Cell Res 1998; 248: 33-41.
44. Kim Y-M, Talanian RV, Billiar TR. Nitric oxide inhibits apoptosis by preventing increases in caspase 3-like activity via two distinct mechanisms. JBC 1997; 49: 31138-31148.
45. Khar A, Pardhasaradhi BVV, Varalakshmi Ch, Ali AM, Kumari AL. Participation of CED-3/ICE and YAMA proteinases in the execution of apoptosis in AK-5 tumor cells leading to spontaneous tumor regression. Cell Immunol 1997; 180: 29-35.