Inactivation of p33ING1 tumor suppressor affects the function of the cell cycle "checkpoints" and stability of the genome

Russian Journal of Genetics

Volumn 36, Issue 3, 2000, Pages 305-312

  Turovets, N A ^a   Agapova, L S ^a   Kopnin, P B ^b   Tulina, N M ^b   Chumakov, P M ^b   Kopnin, B P ^a  

^a INSTITUTE OF BIOMEDICAL CHEMISTRY   (Russian Federation)

^b ENGELHARDT INSTITUTE OF MOLECULAR BIOLOGY   (Russian Federation)

Author keywords

[No Author keywords available]

Indexed keywords

EID: 0001119865     PISSN: 10227954     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (34)

1. ING1 Promotes Neoplastic Transformation, Nat. Genet., 1996, vol. 14, pp. 415-420.
2. ING1 Cooperates with p53 in Cell Growth Control, Nature, 1998, vol. 391, pp. 295-298.
3. Levine, A.J., p53, the Cellular Gatekeeper for Growth and Division, Cell (Cambridge, Mass.), 1997, vol. 88, pp. 323-331.
4. Jacks, T. and Weinberg, R.A., Cell-Cycle Control and Its Watchman, Nature, 1996, vol. 381, pp. 643-644.
5. Ko, L.J. and Prives, C., p53: Puzzle and Paradigm, Genes Dev., 1996, vol. 10, pp. 1054-1072.
6. Chernova, O.B., Chernov, M.V., Agarwal, M.L., et al., The Role of p53 in Regulating Genomic Stability When DNA and RNA Syntheses Are Inhibited, Trends Biochem. Sci., 1995, vol. 20, pp. 431-434.
7. Giaccia, A.J. and Kastan, M.B., The Complexity of p53 Modulation: Emerging Patterns from Divergent Signals, Genes Dev., 1998, vol. 12, pp. 2973-2983.
8. Amundson, S.A., Myers, T.G., and Fornace, A.J., Jr., Roles for p53 in Growth Arrest and Apoptosis: Putting on the Brakes after Genotoxic Stress, Oncogene, 1998, vol. 17, pp. 3287-3299.
9. Taylor, W., Agarwal, M., Agarwal, A., et al., p53 Inhibits Entry into Mitosis When DNA Synthesis Is Blocked, Oncogene, 1998, vol. 18, pp. 283-295.
10. Agarwal, M., Agarwal, A., Taylor, W., et al., A p53-Dependent S-Phase Checkpoint Helps to Protect Cell from DNA Damage in Response to Starvation for Pyrimidine Nucleotides, Proc. Natl. Acad. Sci. USA, 1998, vol. 95, pp. 14775-14780.
11. Livingstone, L.R., White, A., Sprouse, J., et al., Altered Cell Cycle Arrest and Gene Amplification Potential Accompany Loss of Wild-Type p53, Cell (Cambridge, Mass.), 1992, vol. 70, pp. 923-935.
12. Yin, Y., Tainsky, M.A., Bishoff, F.Z., et al., Wild-Type p53 Restores Cell Cycle Control and Inhibits Gene Amplification in Cells with Mutant p53 Alleles, Cell (Cambridge, Mass.), 1992, vol. 70, pp. 937-948.
13. Harvey, M., Sands, A.T., Weiss, R.S., et al., In Vitro Growth Characteristics of Embryo Fibroblasts Isolated from p53-Deficient Mice, Oncogene, 1993, vol. 8, pp. 2456-2467.
14. Lee, J.M., Abrahamson, L.A., Kandel, R., et al., Susceptibility to Radiation Carcinogenesis and Accumulation of Chromosome Breakage in p53-Deficient Mice, Oncogene, 1994, vol. 9, pp. 3731-3736.
15. Agapova, L.S., Ilyinskaya, G.V., Turovets, N.A., et al., Chromosome Changes Caused by Alterations of p53 Expression, Mutat. Res., 1996, vol. 354, pp. 129-138.
16. Fukasawa, K., Wiener, F., Woud, G.F.V., and Mai, S., Genomic Instability and Apoptosis Are Frequent in p53-Deficient Young Mice, Oncogene, 1997, vol. 15, pp. 1295-1302.
17. Ishizaka, Y., Chernov, M.V., Burns, C.M., and Stark, G.R., p53-Dependent Growth Arrest of REF52 Cells Containing Newly Amplified DNA, Proc. Natl. Acad. Sci. USA, 1995, vol. 92, pp. 3224-3228.
18. Zaichuk, T.A., Kuznetsov, N.V., Osovskaya, V.S., et al., Specific DNA-Binding Properties of Oncoprotein p53 from Human Tumor Cells, Dokl. Akad. Nauk, 1993, vol. 330, pp. 386-389.
19. Agapova, L.S., Ivanov, A.V., Sablina, A.A., et al., p53-Dependent Effects of RAS Oncogene on Chromosome Stability and Cell Cycle Checkpoints, Oncogene, 1999, vol. 18, pp. 3135-3142.
20. Ossovskaya, V.S., Mazo, I.A., Chernov, M.V., et al., Use of Genetic Suppressor Elements to Dissect Distinct Biological Effects of Separate p53 Domains, Proc. Natl. Acad. Sci. USA, 1996, vol. 93, pp. 10309-10314.
21. Sablina, A., Agapova, L.S., Chumakov, P.M., and Kopnin, B.P., p53 Does Not Control Spindle Assembly Cell Cycle Checkpoint but Mediates G1 Arrest in Response to Disruption of Microtubule System, Cell Biol. Int., 1999, vol. 23.
22. Stark, G.R., Regulation and Mechanisms of Mammalian Gene Amplification, Adv. Cancer Res., 1993, vol. 61, pp. 87-113.
23. Kelman, Z., PCNA: Structure, Functions, and Interactions, Oncogene, 1997, vol. 14, pp. 629-640.
24. Dutta, A., Ruppert, J.M., Aster, J.C., and Winchester, E., Inhibition of DNA Replication Factor RPA by p53, Nature, 1993, vol. 365, pp. 79-82.
25. Merritt, A., Allen, T., Potten, C., and Hickman, J., Apoptosis in Small Intestinal Epithelia from p53-Null Mice: Evidence for a Delayed, p53-Independent G2/M-Associated Cell Death after γ-Irradiation, Oncogene, 1997, vol. 14, pp. 2759-2766.
26. Di Leonardo, A., Linke, S.P., Clarkin, K., and Wahl, G.M., DNA Damage Triggers a Prolonged p53-Dependent G1 Arrest and Long-Term Induction of Cip1 in Normal Human Fibroblasts, Genes Dev., 1994, vol. 8, pp. 2540-2551.
27. Khan, S.H. and Wahl, G.M., p53 and pRb Prevent Replication in Response to Microtubule Inhibitors by Mediating a Reversible G1 Arrest, Cancer Res., 1998, vol. 58, pp. 396-401.
28. Lanni, J.S. and Jacks, T., Characterization of the p53-Dependent Postmitotic Checkpoint Following Spindle Disruption, Mol. Cell. Biol., 1998, vol. 18, pp. 1055-1064.
29. Notterman, D., Young, S., Wainger, B., and Levine, A.J., Prevention of Mammalian DNA Reduplication, Following the Release from the Mitotic Spindle Checkpoint, Requires p53 Protein, but Not p53-Mediated Transcriptional Activity, Oncogene, 1998, vol. 17, pp. 2743-2751.
30. Perry, M.E., Commane, M., and Stark, G.R., Simian Virus 40 Large Tumor Antigene Alone or Two Cooperating Oncogenes Convert REF52 Cells to a State Permissive for Gene Amplification, Proc. Natl. Acad. Sci. USA, 1992, vol. 89, pp. 8112-8116.
31. Chernova, O., Chernov, M., Ishizaka, Y., et al., MYC Abrogates p53-Mediated Cell Cycle Arrest in N-(Phosphoacetyl)-L-Aspartate-Treated Cells, Permitting CAD Gene Amplification, Mol. Cell. Biol., 1998, vol. 18, pp. 536-545.
32. Ouchi, T., Monteiro, A.N.A., August, A., et al., BRCA1 Regulates p53-Dependent Gene Expression, Proc. Natl. Acad. Sci. USA, 1998, vol. 95, pp. 2302-2306.
33. Zhang, H., Somasundaram, K., Peng, Y., et al., BRCA1 Physically Associates with p53 and Stimulates Its Transcriptional Activity, Oncogene, 1998, vol. 16, pp. 1713-1721.
34. Englert, C., Maheswaran, S., Garvin, A.J., et al., Induction of p21 by the Wilms' Tumor Suppressor Gene WT1, Cancer Res., 1997, vol. 57, pp. 1429-1434.