메뉴 건너뛰기




Volumn 267, Issue 13, 2000, Pages 4198-4204

Cadmium blocks hypoxia-inducible factor (HIF)-1-mediated response to hypoxia by stimulating the proteasome-dependent degradation of HIF-1α

Author keywords

Cadmium; Hypoxia; Hypoxia Inducible factor 1

Indexed keywords

CADMIUM; HYPOXIA INDUCIBLE FACTOR 1; MESSENGER RNA; PROTEASOME;

EID: 0000196439     PISSN: 00142956     EISSN: None     Source Type: Journal    
DOI: 10.1046/j.1432-1327.2000.01453.x     Document Type: Article
Times cited : (81)

References (36)
  • 1
    • 0032053169 scopus 로고    scopus 로고
    • Oxygen sensing, hypoxia-inducible factor-1 and the regulation of mammalian gene expression
    • 1. Ratcliffe, P.J., O'Rourke, J.F., Maxwell, P.H. & Pugh, C.W. (1998) Oxygen sensing, hypoxia-inducible factor-1 and the regulation of mammalian gene expression. J. Exp. Biol. 201, 1153-1162.
    • (1998) J. Exp. Biol. , vol.201 , pp. 1153-1162
    • Ratcliffe, P.J.1    O'Rourke, J.F.2    Maxwell, P.H.3    Pugh, C.W.4
  • 2
    • 1842416574 scopus 로고    scopus 로고
    • Oxygen(es) and the hypoxia-inducible factor-1
    • 2. Wenger, R.H. & Gassmann, M. (1997) Oxygen(es) and the hypoxia-inducible factor-1. Biol. Chem. 378, 609-616.
    • (1997) Biol. Chem. , vol.378 , pp. 609-616
    • Wenger, R.H.1    Gassmann, M.2
  • 3
    • 0029051439 scopus 로고
    • Hypoxia-inducible factor 1 is a basic-helix-loop-helix-PAS heterodimer regulated by cellular O2 tension
    • 3. Wang, G.L., Jiang, B.H., Rue, E.A. & Semenza, G.L. (1995) Hypoxia-inducible factor 1 is a basic-helix-loop-helix-PAS heterodimer regulated by cellular O2 tension. Proc. Natl Acad. Sci. USA 92, 5510-5514.
    • (1995) Proc. Natl Acad. Sci. USA , vol.92 , pp. 5510-5514
    • Wang, G.L.1    Jiang, B.H.2    Rue, E.A.3    Semenza, G.L.4
  • 4
    • 0029753008 scopus 로고    scopus 로고
    • Activation of hypoxia-inducible transcription factor depends primarily upon redox-sensitive stabilization of its α subunit
    • 4. Huang, L.E., Arany, Z., Livingston, D.M. & Bunn, H.F. (1996) Activation of hypoxia-inducible transcription factor depends primarily upon redox-sensitive stabilization of its α subunit. J. Biol. Chem. 271, 32253-32259.
    • (1996) J. Biol. Chem. , vol.271 , pp. 32253-32259
    • Huang, L.E.1    Arany, Z.2    Livingston, D.M.3    Bunn, H.F.4
  • 5
    • 0030961006 scopus 로고    scopus 로고
    • Hypoxia-inducible factor 1α (HIF-1α) protein is rapidly degraded by the ubiquitin-proteasome system under normoxic conditions. Its stabilization by hypoxia depends on redox-induced changes
    • 5. Salceda, S. & Caro, J. (1997) Hypoxia-inducible factor 1α (HIF-1α) protein is rapidly degraded by the ubiquitin-proteasome system under normoxic conditions. Its stabilization by hypoxia depends on redox-induced changes. J. Biol. Chem. 272, 22642-22647.
    • (1997) J. Biol. Chem. , vol.272 , pp. 22642-22647
    • Salceda, S.1    Caro, J.2
  • 7
    • 0029842459 scopus 로고    scopus 로고
    • Oxygen sensing and molecular adaptation to hypoxia
    • 7. Bunn, H.F. & Poyton, R.O. (1996) Oxygen sensing and molecular adaptation to hypoxia. Physiol. Rev. 76, 839-885.
    • (1996) Physiol. Rev. , vol.76 , pp. 839-885
    • Bunn, H.F.1    Poyton, R.O.2
  • 8
    • 0032190614 scopus 로고    scopus 로고
    • Hypoxia-inducible factor 1: Master regulator of O2 homeostasis
    • 8. Semenza, G.L. (1998) Hypoxia-inducible factor 1: master regulator of O2 homeostasis. Curr. Opin. Genet. Dev. 8, 588-594.
    • (1998) Curr. Opin. Genet. Dev. , vol.8 , pp. 588-594
    • Semenza, G.L.1
  • 9
    • 0029088495 scopus 로고
    • Cadmium-associated renal disease
    • 9. Savolainen, H. (1995) Cadmium-associated renal disease. Ren. Fail. 17, 483-487.
    • (1995) Ren. Fail. , vol.17 , pp. 483-487
    • Savolainen, H.1
  • 10
    • 0000464967 scopus 로고
    • Cadmium
    • (Friberg, L., Nordberg, G.F. & Vouk, V.B., eds.), Elsevier, Amsterdam, the Netherlands
    • 10. Friberg, L., Kjellstrom, T. & Nordberg, G.F. (1986) Cadmium. In Handbook on the Toxicology of Metals (Friberg, L., Nordberg, G.F. & Vouk, V.B., eds.), pp. 130-184. Elsevier, Amsterdam, the Netherlands.
    • (1986) Handbook on the Toxicology of Metals , pp. 130-184
    • Friberg, L.1    Kjellstrom, T.2    Nordberg, G.F.3
  • 11
    • 0027943676 scopus 로고
    • Hypoproduction of erythropoietin contributes to anemia in chronic cadmium intoxication: Clinical study on Itai-itai disease in Japan
    • 11. Horiguchi, H., Teranishi, H., Niiya, K., Aoshima, K., Katoh, T., Sakuragawa, N. & Kasuya, M. (1994) Hypoproduction of erythropoietin contributes to anemia in chronic cadmium intoxication: clinical study on Itai-itai disease in Japan. Arch. Toxicol. 68, 632-636.
    • (1994) Arch. Toxicol. , vol.68 , pp. 632-636
    • Horiguchi, H.1    Teranishi, H.2    Niiya, K.3    Aoshima, K.4    Katoh, T.5    Sakuragawa, N.6    Kasuya, M.7
  • 12
    • 0029823743 scopus 로고    scopus 로고
    • Long-term cadmium exposure induces anemia in rats through hypo-induction of erythropoietin in the kidneys
    • 12. Horiguchi, H., Sato, M., Konno, N. & Fukushima, M. (1996) Long-term cadmium exposure induces anemia in rats through hypo-induction of erythropoietin in the kidneys. Arch. Toxicol. 71, 11-19.
    • (1996) Arch. Toxicol. , vol.71 , pp. 11-19
    • Horiguchi, H.1    Sato, M.2    Konno, N.3    Fukushima, M.4
  • 15
    • 0030914648 scopus 로고    scopus 로고
    • Activation of hypoxia-inducible factor 1α: Posttranscriptional regulation and conformational change by recruitment of the Arnt transcription factor
    • 15. Kallio, P.J., Pongratz, I., Gradin, K., McGuire, J. & Poellinger, L. (1997) Activation of hypoxia-inducible factor 1α: posttranscriptional regulation and conformational change by recruitment of the Arnt transcription factor. Proc. Natl Acad. Sci. USA 94, 5667-5672.
    • (1997) Proc. Natl Acad. Sci. USA , vol.94 , pp. 5667-5672
    • Kallio, P.J.1    Pongratz, I.2    Gradin, K.3    McGuire, J.4    Poellinger, L.5
  • 16
    • 0032547073 scopus 로고    scopus 로고
    • Expression of plasma phospholipid transfer protein mRNA in normal and emphysematous lungs and regulation by hypoxia
    • 16. Jiang, X.C., D'Armiento, J., Mallampalli, R.K., Mar, J., Yan, S.F. & Lin, M. (1998) Expression of plasma phospholipid transfer protein mRNA in normal and emphysematous lungs and regulation by hypoxia. J. Biol. Chem. 273, 15714-15718.
    • (1998) J. Biol. Chem. , vol.273 , pp. 15714-15718
    • Jiang, X.C.1    D'Armiento, J.2    Mallampalli, R.K.3    Mar, J.4    Yan, S.F.5    Lin, M.6
  • 17
    • 0032190196 scopus 로고    scopus 로고
    • Identification of oxidized proteins based on sodium dodecyl sulfate-polyacrylamide gel electrophoresis, immunochemical detection, isoelectric focusing, and microsequencing
    • 17. Yan, L.J., Orr, W.C. & Sohal, R.S. (1998) Identification of oxidized proteins based on sodium dodecyl sulfate-polyacrylamide gel electrophoresis, immunochemical detection, isoelectric focusing, and microsequencing. Anal. Biochem. 263, 67-71.
    • (1998) Anal. Biochem. , vol.263 , pp. 67-71
    • Yan, L.J.1    Orr, W.C.2    Sohal, R.S.3
  • 19
    • 0032891708 scopus 로고    scopus 로고
    • Induction and nuclear translocation of hypoxia-inducible factor-1 (HIF-1): Heterodimerization with ARNT is not necessary for nuclear accumulation of HIF-1α
    • 19. Chilov, D., Camenisch, G., Kvietikova, I., Ziegler, U., Gassmann, M. & Wenger, R.H. (1999) Induction and nuclear translocation of hypoxia-inducible factor-1 (HIF-1): heterodimerization with ARNT is not necessary for nuclear accumulation of HIF-1α. J. Cell. Sci. 112, 1203-1212.
    • (1999) J. Cell. Sci. , vol.112 , pp. 1203-1212
    • Chilov, D.1    Camenisch, G.2    Kvietikova, I.3    Ziegler, U.4    Gassmann, M.5    Wenger, R.H.6
  • 20
    • 0031754373 scopus 로고    scopus 로고
    • Mersalyl is a novel inducer of vascular endothelial growth factor gene expression and hypoxia-inducible factor 1 activity
    • 20. Agani, F. & Semenza, G.L. (1998) Mersalyl is a novel inducer of vascular endothelial growth factor gene expression and hypoxia-inducible factor 1 activity. Mol. Pharmacol. 54, 749-754.
    • (1998) Mol. Pharmacol. , vol.54 , pp. 749-754
    • Agani, F.1    Semenza, G.L.2
  • 21
    • 0033593219 scopus 로고    scopus 로고
    • Oxygen-regulated and transactivating domains in endothelial PAS protein 1: Comparison with hypoxia-inducible factor-1α
    • 21. O'Rourke, J.F., Tian, Y.M., Ratcliffe, P.J. & Pugh, C.W. (1999) Oxygen-regulated and transactivating domains in endothelial PAS protein 1: comparison with hypoxia-inducible factor-1α. J. Biol. Chem. 274, 2060-2071.
    • (1999) J. Biol. Chem. , vol.274 , pp. 2060-2071
    • O'Rourke, J.F.1    Tian, Y.M.2    Ratcliffe, P.J.3    Pugh, C.W.4
  • 22
    • 0033525830 scopus 로고    scopus 로고
    • Regulation of the hypoxia-inducible transcription factor 1α by the ubiquitin-proteasome pathway
    • 22. Kallio, P.J., Wilson, W.J., O'Brien, S., Makino, Y. & Poellinger, L. (1999) Regulation of the hypoxia-inducible transcription factor 1α by the ubiquitin-proteasome pathway. J. Biol. Chem. 274, 6519-6525.
    • (1999) J. Biol. Chem. , vol.274 , pp. 6519-6525
    • Kallio, P.J.1    Wilson, W.J.2    O'Brien, S.3    Makino, Y.4    Poellinger, L.5
  • 23
    • 0028798434 scopus 로고
    • Oxidative mechanisms in the toxicity of metal ions
    • 23. Stohs, S.J. & Bagchi, D. (1995) Oxidative mechanisms in the toxicity of metal ions. Free. Radic. Biol. Med. 18, 321-336.
    • (1995) Free. Radic. Biol. Med. , vol.18 , pp. 321-336
    • Stohs, S.J.1    Bagchi, D.2
  • 25
    • 0022921079 scopus 로고
    • Consequences of cadmium toxicity in rat hepatocytes: Mitochondrial dysfunction and lipid peroxidation
    • 25. Muller, L. (1986) Consequences of cadmium toxicity in rat hepatocytes: mitochondrial dysfunction and lipid peroxidation. Toxicology 40, 285-295.
    • (1986) Toxicology , vol.40 , pp. 285-295
    • Muller, L.1
  • 26
    • 0028906222 scopus 로고
    • Inhibition kinetics of sheep brain glutathione reductase by cadmium ion
    • 26. Acan, N.L. & Tezcan, E.F. (1995) Inhibition kinetics of sheep brain glutathione reductase by cadmium ion. Biochem. Mol. Med. 54, 33-37.
    • (1995) Biochem. Mol. Med. , vol.54 , pp. 33-37
    • Acan, N.L.1    Tezcan, E.F.2
  • 27
    • 0026666025 scopus 로고
    • Role of oxidative stress in single-dose, cadmium-induced testicular cancer
    • 27. Koizumi, T. & Li, Z.G. (1992) Role of oxidative stress in single-dose, cadmium-induced testicular cancer. J. Toxicol. Environ. Health. 37, 25-36.
    • (1992) J. Toxicol. Environ. Health. , vol.37 , pp. 25-36
    • Koizumi, T.1    Li, Z.G.2
  • 28
    • 0023201838 scopus 로고
    • Effects of cadmium on Superoxide dismutase and lipid peroxidation in liver and kidney of growing rats: In vivo and in vitro studies
    • 28. Hussain, T., Shukla, G.S. & Chandra, S.V. (1987) Effects of cadmium on Superoxide dismutase and lipid peroxidation in liver and kidney of growing rats: in vivo and in vitro studies. Pharmacol. Toxicol. 60, 355-358.
    • (1987) Pharmacol. Toxicol. , vol.60 , pp. 355-358
    • Hussain, T.1    Shukla, G.S.2    Chandra, S.V.3
  • 29
    • 0028845979 scopus 로고
    • Cadmium-induced lipid peroxidation and the status of the antioxidant system in rat tissues
    • 29. Sarkar, S., Yadav, P., Trivedi, R., Bansal, A.K. & Bhatnagar, D. (1995) Cadmium-induced lipid peroxidation and the status of the antioxidant system in rat tissues. J. Trace. Elem. Med. Biol. 9, 144-149.
    • (1995) J. Trace. Elem. Med. Biol. , vol.9 , pp. 144-149
    • Sarkar, S.1    Yadav, P.2    Trivedi, R.3    Bansal, A.K.4    Bhatnagar, D.5
  • 30
    • 0023610954 scopus 로고
    • Indirect evidence for the induction of a prooxidant state by cadmium chloride in cultured mammalian cells and a possible mechanism for the induction
    • 30. Ochi, T., Takahashi, K. & Ohsawa, M. (1987) Indirect evidence for the induction of a prooxidant state by cadmium chloride in cultured mammalian cells and a possible mechanism for the induction. Mutat. Res. 180, 257-266.
    • (1987) Mutat. Res. , vol.180 , pp. 257-266
    • Ochi, T.1    Takahashi, K.2    Ohsawa, M.3
  • 31
    • 0032557581 scopus 로고    scopus 로고
    • Disruption of the intracellular sulfhydryl homeostasis by cadmium-induced oxidative stress leads to protein thiolation and ubiquitination in neuronal cells
    • 31. Figueiredo-Pereira, M.E., Yakushin, S. & Cohen, G. (1998) Disruption of the intracellular sulfhydryl homeostasis by cadmium-induced oxidative stress leads to protein thiolation and ubiquitination in neuronal cells. J. Biol. Chem. 273, 12703-12709.
    • (1998) J. Biol. Chem. , vol.273 , pp. 12703-12709
    • Figueiredo-Pereira, M.E.1    Yakushin, S.2    Cohen, G.3
  • 32
    • 0030841350 scopus 로고    scopus 로고
    • Protein oxidation in aging, disease, and oxidative stress
    • 32. Berlett, B.S. & Stadtman, E.R. (1997) Protein oxidation in aging, disease, and oxidative stress. J. Biol. Chem. 272, 20313-20316.
    • (1997) J. Biol. Chem. , vol.272 , pp. 20313-20316
    • Berlett, B.S.1    Stadtman, E.R.2
  • 33
    • 0031583990 scopus 로고    scopus 로고
    • Metal-induced metallothionein gene expression can be inactivated by protein kinase C inhibitor
    • 33. Yu, C.W., Chen, J.H. & Lin, L.Y (1997) Metal-induced metallothionein gene expression can be inactivated by protein kinase C inhibitor. FEBS Lett. 420, 69-73.
    • (1997) FEBS Lett. , vol.420 , pp. 69-73
    • Yu, C.W.1    Chen, J.H.2    Lin, L.Y.3
  • 34
    • 0031956516 scopus 로고    scopus 로고
    • The rat heme oxygenase-1 gene is transcriptionally induced via the protein kinase A signaling pathway in rat hepatocyte cultures
    • 34. Immenschuh, S., Kietzmann, T., Hinke, V., Wiederhold, M., Katz, N. & Muller-Eberhard, U. (1998) The rat heme oxygenase-1 gene is transcriptionally induced via the protein kinase A signaling pathway in rat hepatocyte cultures. Mol. Pharmacol. 53, 483-491.
    • (1998) Mol. Pharmacol. , vol.53 , pp. 483-491
    • Immenschuh, S.1    Kietzmann, T.2    Hinke, V.3    Wiederhold, M.4    Katz, N.5    Muller-Eberhard, U.6
  • 35
    • 0031690007 scopus 로고    scopus 로고
    • Involvement of the tyrosine phosphorylation pathway in induction of human heme oxygenase-1 by hemin, sodium arsenite, and cadmium chloride
    • 35. Masuya, Y., Hioki, K., Tokunaga, R. & Taketani, S. (1998) Involvement of the tyrosine phosphorylation pathway in induction of human heme oxygenase-1 by hemin, sodium arsenite, and cadmium chloride. J. Biochem. (Tokyo) 124, 628-633.
    • (1998) J. Biochem. (Tokyo) , vol.124 , pp. 628-633
    • Masuya, Y.1    Hioki, K.2    Tokunaga, R.3    Taketani, S.4
  • 36
    • 0033610798 scopus 로고    scopus 로고
    • Differential activation of p38 mitogen-activated protein kinase and extracellular signal-regulated protein kinases confers cadmium-induced HSP70 expression in 9L rat brain tumor cells
    • 36. Hung, J.J., Cheng, T.J., Lai, Y.K. & Chang, M.D. (1998) Differential activation of p38 mitogen-activated protein kinase and extracellular signal-regulated protein kinases confers cadmium-induced HSP70 expression in 9L rat brain tumor cells. J. Biol. Chem. 273, 31924-31931.
    • (1998) J. Biol. Chem. , vol.273 , pp. 31924-31931
    • Hung, J.J.1    Cheng, T.J.2    Lai, Y.K.3    Chang, M.D.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.