Minimal dead-volume connectors for microfluidics using PDMS casting techniques

Journal of Micromechanics and Microengineering

Volumn 14, Issue 11, 2004, Pages 1484-1490

  Chiou, Chi Han ^a   Lee, Gwo Bin ^a  

^a NATIONAL CHENG KUNG UNIVERSITY   (Taiwan)

Author keywords

[No Author keywords available]

Indexed keywords

ADHESIVES; CAPILLARITY; ELECTROPHORESIS; LIQUID CHROMATOGRAPHY; MICROMACHINING; POLYMERS; POLYTETRAFLUOROETHYLENES;

MICRO-CONNECTORS; MICROFLUIDIC APPLICATIONS; SODIUM DODECYL SULFATE (SDS);

MICROELECTROMECHANICAL DEVICES;

EID: 9644303044     PISSN: 09601317     EISSN: None     Source Type: Journal    
DOI: 10.1088/0960-1317/14/11/008     Document Type: Article

References (23)

1. Manz A, Harrison D J, Verpoorte E M J, Fettinger J C, Paulus A, Ludi H and Widmer H M 1992 Planar chips technology for miniaturization and integration of separation techniques into monitoring systems-capillary electrophoresis on a chip J. Chromatogr. 593 253-8
2. Bruns M A et al 1999 An integrated nanoliter DNA analysis device Science 282 484-7
3. Mouradian S 2001 Lab-on-a-chip: applications in proteomics Curr. Opin. Chem. Biol. 6 51-6
4. Chervet J P and Ursem M 1996 Instrumental requirements for nanoscale liquid chromatography Anal. Chem. 68 1507-12
5. Veraart J R, Lingeman H and Brinkman U A T 1999 Coupling of biological sample handing and capillary electrophoresis J. Chromatogr. A 856 483-513
6. Jiang Y, Wang P C, Locascio L E and Lee C S 2001 Integrated plastic microfluidic devices with ESI-MS for drug screening and residue analysis Anal. Chem. 73 2048-53
7. Bings N H, Wang C, Skinner C D, Colyer C L, Thibault P and Harrison D J 1999 Microfluidic devices connected to fused-silica capillaries with minimal dead volume Anal. Chem. 71 3292-6
8. Li J, Thibault P, Bings N H, Skinner C D, Wang C, Colyer C and Harrison J 1999 Integration of microfabricated devices to capillary electrophoresis- electrospray mass spectrometry using a low dead volume connection: application to rapid analyses of proteolytic digests Anal. Chem. 71 3036-45
9. Tsai J H and Lin L 2001 Micro-to-macro fluidic interconnectors with an integrated polymer sealant J. Micromech. Microeng. 11 577-81
10. Puntambekar A and Ahn C H 2002 Self-aligning microfluidic interconnects for glass- and plastic-based microfluidic systems J. Micromech. Microeng. 12 35-40
11. Lin C C, Lee G B and Chen S H 2002 Automation for continuous analysis on microchip electrophoresis using flow-through sampling Electrophoresis 23 3550-7
12. Obeid P J, Christopoulos T K, Crabtree H J and Backhouse C J 2003 Microfabricated device for DNA and RNA amplification by continuous-flow polymerase chain reaction and reverse transcription-polymerase chain reaction with cycle number selection Anal. Chem. 75 288-95
13. Gonzalez C, Collins S D and Smith R L 1997 Fluidic interconnects for modular assembly of chemical microsystems 9th Int. Conf. Solid-State Sensors and Actuators (Transducers '97) pp 527-30
14. Spiering V L, van der Moolen J N, Burger G J and van der Berg A 1997 Novel microstructures and technologies applied in chemical analysis techniques 9th Int. Conf. Solid-State Sensors and Actuators (Transducers '97) pp 511-4
15. Gray B L, Jaeggi D, Mourlas N J, van Drieenhuizen B P, Williams K R, Maluf N I and Kovacs G T A 1999 Novel interconnection technologies for integrated microfluidic systems Sensors Actuators A 77 57-65
16. Yao T J, Lee S, Fang W and Tai Y C 2000 Micromachined rubber O-ring micro-fluidic couplers 13th IEEE Int. Conf. on Micro Electro Mechanical Systems (MEMS'00) pp 624-7
17. Gray B L, Collins S D and Smith R L 2001 Interlocking mechanical and microfluidic interconnections fabricated by deep reactive ion etching Micro Total Analysis Systems 2001(μTAS'01) pp 153-4
18. Shaikh K, Ryu K S, Fan Z and Liu C 2003 Interconnects with low dead volumes and integrated back-plane fluid jumpers Micro Total Analysis Systems 2003 (μTAS '03) pp 1053-6
19. Chabinyc M L, Chiu D T, McDonald J C, Stroock A D, Christian J F, Karger A M and Whitesides G M 2001 An integrated fluorescence detection system in poly (dimethylsiloxane) for microfluidic applications Anal. Chem. 73 4491-8
20. Chiou C H, Lee G B, Hsu H T, Chen P W and Liao P C 2002 Micro devices integrated with microchannels and electrospray nozzles using PDMS casting techniques Sensors Actuators B 86 280-6
21. Kim H, Ro K W, Lim K, Park N, Kim M and Hahn J H 2002 Adhesive and dead volume free interfacing between PDMS microfluidic channels Micro Total Analysis Systems 2002 (μTAS '02) pp 401-3
22. Matsumoto S, Xie J and Tai Y C 2003 Polymer micro interface for fluidic probing Micro Total Analysis Systems 2003 (μTAS '03) pp 551-4
23. Lin C H, Lee G B, Lin Y H and Chang G L 2001 A fast-prototyping process for fabrication of microfluidic systems on soda-lime glass J. Micromech. Microeng. 11 726-32