Lab-on-a-chip: Applications in proteomics

Current Opinion in Chemical Biology

Volumn 6, Issue 1, 2002, Pages 51-56

  Mouradian, Stephane ^a  

^a Caliper Life Sciences   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

TRYPSIN;

ANALYTIC METHOD; AUTOMATION; CAPILLARY ELECTROCHROMATOGRAPHY; CAPILLARY ELECTROPHORESIS; DEVICE; FLUORESCENCE; INTERMETHOD COMPARISON; MASS SPECTROMETER; MASS SPECTROMETRY; POLYACRYLAMIDE GEL ELECTROPHORESIS; PROTEIN ANALYSIS; PROTEOMICS; REVIEW; TWO DIMENSIONAL GEL ELECTROPHORESIS;

EID: 0036468613     PISSN: 13675931     EISSN: None     Source Type: Journal    
DOI: 10.1016/S1367-5931(01)00280-0     Document Type: Review

References (38)

1. Electrophoretic separation of proteins on a microchip with noncovalent, postcolumn labeling
2. Protein sizing on a microchip
3. Two dimensional electrochromatography/capillary electrophoresis on a microchip
4. A microfabricated fluidic device for performing two-dimensional liquid-phase separations
5. Electroosmosis- and pressure-driven chromatography in chips using continuous beds
6. Reversed-phase electrochromatography of amino acids and peptides using porous polymer monoliths
7. Room-temperature imprinting method for plastic microchannel fabrication
8. Concentration and separation of proteins in microfluidic channels on the basis of transverse IEF
9. Development of a multichannel microfluidic analysis system employing affinity capillary electrophoresis for immunoassay
10. Integration of an immunosorbent assay system: Analysis of secretory human immunoglobulin A on polystyrene beads in a microchip
11. Electrokinetically driven microfluidic chips with surface-modified chambers for heterogeneous immunoassays
12. New approaches for innovations in sensitive Edman sequence analysis by design of a wafer-based chip sequencer
13. A fully Integrated monolithic microchip electrospray device for mass spectrometry
14. A micromachined chip-based electrospray source for mass spectrometry
15. An enhanced microfluidic chip coupled to an electrospray Qstar mass spectrometer for protein identification
16. Novel microfabricated device for electrokinetically induced pressure flow and electrospray ionization mass spectrometry
17. Generation of multiple electrosprays using microfabricated emitter arrays for improved mass spectrometric sensitivity
18. An automated microchip-based electrospray device for high throughput MS analysis
19. Electrospray device for coupling microscale separations and other miniaturized devices with electrospray mass spectrometry
20. Multichannel devices with an array of electrospray tips for high-throughput mass spectrometry
21. A microdevice with integrated liquid junction for facile peptide and protein analysis by capillary electrophoresis/electrospray mass spectrometry
22. High-throughput microfabricated CE/ESI-MS: Automated sampling from a microwell plate
23. Automated high-throughput infusion ESI-MS with direct coupling to a microtiter plate
24. Separation and identification of peptides from gel-isolated membrane proteins using a microfabricated device for combined capillary electrophoresis / nanoelectrospray mass spectrometry
25. Rapid and sensitive separation of trace level protein digests using microfabricated devices coupled to a quadrupole-time-of-flight mass spectrometer
26. Chip-based capillary electrophoresis/mass spectrometry determination of carnitines in human urine
27. Microfabricated isoelectric focusing device for direct electrospray ionization-mass spectrometry
28. On-chip proteolytic digestion and analysis using "wrong-way-round" electrospray time-of-flight mass spectrometry
29. Integrated microfluidic system enabling protein digestion, peptide separation, and protein identification
30. Integration of immobilized trypsin bead beds for protein digestion within a microfluidic chip incorporating capillary electrophoresis separations and an electrospray mass spectrometry interface
31. Integrated microanalytical technology enabling rapid and automated protein identification
32. Silicon microstructures for high-speed and high-sensitivity protein identifications
33. Integrated microchip-device for the digestion, separation and postcolumn labeling of proteins and peptides
34. Dynamic labeling during capillary or microchip electrophoresis for laser-induced fluorescence detection of protein-SDS complexes without pre- or postcolumn labeling
35. Microchip isoelectric focusing using a miniature scanning detection system
36. A disposable poly(methylmethacrylate)-based microfluidic module for protein identification by nanoelectrospray ionization-tandem mass spectrometry
37. Stable sol-gel microstructured and microfluidic networks for protein patterning
38. Integrated system for high-throughput protein identification using a microfabricated device coupled to capillary electrophoresis/nanoelectrospray mass spectrometry