Acute exposure to GSM 900-MHz electromagnetic fields induces glial reactivity and biochemical modifications in the rat brain

Neurobiology of Disease

Volumn 17, Issue 3, 2004, Pages 445-454

  Mausset Bonnefont, Anne Laure ^a   Hirbec, Hélène ^a   Bonnefont, Xavier ^b   Privat, Alain ^a   Vignon, Jacques ^a   De Sèze, René ^c  

^a Montpellier University Medical Center   (France)

^b INSERM   (France)

^c INSTITUT NATIONAL DE L ENVIRONNEMENT INDUSTRIEL ET DES RISQUES INERIS   (France)

Author keywords

Brain; Glia; Microwaves; Mobile phones; Neurotransmitters; Public health

Indexed keywords

4 AMINOBUTYRIC ACID A RECEPTOR; DOPAMINE TRANSPORTER; N METHYL DEXTRO ASPARTIC ACID RECEPTOR;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; BRAIN; CHEMICAL MODIFICATION; CONTROLLED STUDY; CORPUS STRIATUM; DEVICE; ELECTROMAGNETIC FIELD; GLIA; GLOBAL SYSTEM FOR MOBILE COMMUNICATION; LOCOMOTION; MALE; MICROWAVE RADIATION; NONHUMAN; POSTSYNAPTIC MEMBRANE; PRIORITY JOURNAL; RAT;

ANIMALS; AUTORADIOGRAPHY; BRAIN; DOPAMINE PLASMA MEMBRANE TRANSPORT PROTEINS; ELECTROMAGNETIC FIELDS; GLIAL FIBRILLARY ACIDIC PROTEIN; MALE; MEMBRANE GLYCOPROTEINS; MEMBRANE TRANSPORT PROTEINS; MICROWAVES; MOTOR ACTIVITY; NERVE TISSUE PROTEINS; NEUROGLIA; NEUROTRANSMITTER AGENTS; RATS; RATS, WISTAR; RECEPTORS, GABA-A; RECEPTORS, N-METHYL-D-ASPARTATE; TIME FACTORS; TRITIUM;

EID: 9644290883     PISSN: 09699961     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.nbd.2004.07.004     Document Type: Article

References (32)

1. M.J. Clague, and S. Urbe The interface of receptor trafficking and signalling J. Cell Sci. 114 2001 3075 3081
2. D. Dubreuil, T. Jay, and J.-M. Edeline Does head-only exposure to GSM-900 MHz electromagnetic fields affect the performance of rats in spatial learning tasks? Behav. Brain Res. 129 2002 203 210
3. D. Dubreuil, T. Jay, and J.-M. Edeline Head-only exposure to GSM-900 MHz electromagnetic fields does not alter rat's memory in spatial and non-spatial tasks Behav. Brain Res. 145 2003 51 61
4. N. Edelstyn, and A. Oldershaw The acute effects of exposure to the electromagnetic field emitted by mobile phones on human attention NeuroReport 13 2002 119 121
5. P.W. French, R. Penny, J.A. Laurence, and D.R. McKenzie Mobile phones, heat shock proteins and cancer Differentiation 67 2001 93 97
6. Gabriel, C., et al., 1996. 4-Cole-Cole Analysis. Compilation of the Dielectric properties of body tissues at RF and microwave frequencies, Brooks Air Force Technical Report AL/OE-TR-1996-0037.
7. R.R. Gainetdinov, S.R. Jones, F. Fumagalli, R.M. Wightman, and M.G. Caron Re-evaluation of the role of the dopamine transporter in dopamine system homeostasis Brain Res. Brain Res. Rev. 26 1998 148 153
8. D.L. Hamblin, and A.W. Wood Effects of mobile phone emissions on human brain activity and sleep variables Int. J. Radiat. Biol. 78 2002 659 669
9. D.M. Hermann, and K.A. Hossmann Neurological effects of microwave exposure related to mobile communication J. Neurol. Sci. 152 1997 1 14
10. M. Koivisto, C.M. Krause, A. Revonsuo, M. Laine, and H. Hämäläinen The effects of electromagnetic field emitted by GSM phones on working memory NeuroReport 11 2000 1641 1643
11. M. Koivisto, A. Revonsuo, C.M. Krause, C. Haarala, L. Sillanmäki, M. Laine, and H. Hämäläinen Effects of 902 MHz electromagnetic field emitted by cellular telephones on response times in humans NeuroReport 11 2000 1 3
12. O. Kolomytkin, M. Yurinska, S. Zharikov, V. Kuznetsov, and A. Zharikova Response of brain receptor systems to microwave energy exposure A.H. Frey On the Nature of Electromagnetic Field Interactions With Biological Systems 1994 R.G. Landes Company Austin 195 206
13. W.J. Koroshetz, and J.V. Bonventre Heat shock response in the central nervous system Experientia 50 1994 1085 1091
14. H. Lai Neurological effects of radiofrequency electromagnetic radiation J.C. Lin Advances in Electromagnetic Fields in Living Systems vol. 1 1994 Plenum New York 27 80
15. E. Layne Spectrophotometric and turbidimetric methods for measuring proteins Methods Enzymol. 10 1957 447 455
16. T.M.C. Lee, S.M.Y. Ho, L.Y.H. Tsang, S.Y.C. Yang, L.S.W. Li, and C.C.H. Chan Effect on human attention of exposure to the electromagnetic field emitted by mobile phones NeuroReport 12 2001 729 731
17. D. Leszczynski, S. Joenvaara, J. Reivinen, and R. Kuokka Non-thermal activation of the hsp27/p38MAPK stress pathway by mobile phone radiation in human endothelial cells: molecular mechanism for cancer- and blood-brain barrier-related effects Differentiation 70 2002 120 129
18. A.L. Mammen, and R.L. Huganir Regulation of NMDA receptors by protein phosphorylation D.T. Monaghan R.J. Wenthold The Ionotropic Glutamate Receptors 1997 Humana Press Inc Totowa, NJ 349 372
19. A.-L. Mausset, R. de Sèze, F. Montpeyroux, and A. Privat Effects of radiofrequency exposure on the GABAergic system in the rat cerebellum: clues from semi-quantitative immunohistochemistry Brain Res. 912 2001 33 46
20. A.-L. Mausset-Bonnefont, R. de Sèze, and A. Privat Immunohistochemistry as a tool for topographical semi-quantification of neurotransmitters in the brain Brain Res. Protoc. 10 2003 148 155
21. Y.M. Moustafa, R.M. Moustafa, A. Belacy, S.H. Abou-El-Ela, and F.M. Ali Effects of acute exposure to the radiofrequency fields of cellular phones on plasma lipid peroxide and antioxidase activities in human erythrocytes J. Pharm. Biomed. Anal. 26 2001 605 608
22. S. Pacini, M. Ruggiero, I. Sardi, S. Aterini, F. Gulisano, and M. Gulisano Exposure to global system for mobile communication (GSM) cellular phone radiofrequency alters gene expression, proliferation, and morphology of human skin fibroblasts Oncol. Res. 13 2002 19 24
23. A.W. Preece, G. Iwi, A. Davies-Smith, K. Wesnes, S. Butler, E. Lim, and A. Varey Effect of a 915-MHz simulated mobile phone signal on cognitive function in man Int. J. Radiat. Biol. 75 1999 447 456
24. P. Rataboul, N. Faucon-Biguet, P. Vernier, F. De Vitry, S. Boularand, A. Privat, and J. Mallet Identification of a human glial fibrillary acidic protein cDNA: a tool for the molecular analysis of reactive gliosis in the mammalian central nervous system J. Neurosci. Res. 20 1988 165 175
25. M.H. Repacholi Health risks from the use of mobile phones Toxicol. Lett. 120 2001 323 331
26. J.L. Ridet, and A. Privat Reactive astrocytes, their roles in CNS injury, and repair mechanisms Adv. Struct. Biol. 6 2000 147 185
27. R. Sattler, and M. Tymianski Molecular mechanisms of calcium-dependent excitotoxicity J. Mol. Med. 78 2000 3 13
28. A. Takashima, and S. Itoh Memory impairment induced by CCK-8 antagonists in passive avoidance response of the rat Drug Dev. Res. 18 1989 95 100
29. G. Testylier, L. Tonduli, R. Malabiau, and J.C. Debouzy Effects of exposure to low level radiofrequency fields on acetylcholine release in hippocampus of freely moving rats Bioelectromagnetics 23 2002 249 255
30. 3H]BTCP): a new phencyclidine analog selective for the dopamine uptake complex Eur. J. Pharmacol. 148 1988 427 436
31. 3H] TCP) binding properties to rat and human brain membranes Life Sci. 45 1989 2547 2555
32. A receptor mRNA levels and GABA stimulation of benzodiazepine binding with no effect on benzodiazepine binding site density J. Pharmacol. Exp. Ther. 289 1999 1626 1633