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Volumn 53, Issue SUPPL. 3, 2004, Pages

Suppression of β-cell secretion by somatostatin does not fully reverse the disproportionate proinsulinemia of type 2 diabetes

Author keywords

[No Author keywords available]

Indexed keywords

ARGININE; C PEPTIDE; PROINSULIN; SOMATOSTATIN;

EID: 9444233893     PISSN: 00121797     EISSN: None     Source Type: Journal    
DOI: 10.2337/diabetes.53.suppl_3.S22     Document Type: Conference Paper
Times cited : (8)

References (22)
  • 1
    • 0017761172 scopus 로고
    • Circulating proinsulin in patients with maturity onset diabetes
    • Mako ME, Starr JI, Rubenstein AH: Circulating proinsulin in patients with maturity onset diabetes. Am J Med 63:865-869, 1977
    • (1977) Am J Med , vol.63 , pp. 865-869
    • Mako, M.E.1    Starr, J.I.2    Rubenstein, A.H.3
  • 2
    • 0031791047 scopus 로고    scopus 로고
    • Disproportionately elevated proinsulin levels reflect the degree of impaired B cell secretory capacity in patients with noninsulin-dependent diabetes mellitus
    • Røder ME, Porte D Jr, Schwartz RS, Kahn SE: Disproportionately elevated proinsulin levels reflect the degree of impaired B cell secretory capacity in patients with noninsulin-dependent diabetes mellitus. J Clin Endocrinol Metab 83:604-608, 1998
    • (1998) J Clin Endocrinol Metab , vol.83 , pp. 604-608
    • Røder, M.E.1    Porte Jr., D.2    Schwartz, R.S.3    Kahn, S.E.4
  • 3
    • 0030781055 scopus 로고    scopus 로고
    • The relation of proinsulin, insulin, and proinsulin-to-insulin ratio to insulin sensitivity and acute insulin response in normoglycemic subjects
    • Mykkänen L, Haffner SM, Hales CN, Rönnemaa T, Laakso M: The relation of proinsulin, insulin, and proinsulin-to-insulin ratio to insulin sensitivity and acute insulin response in normoglycemic subjects. Diabetes 46:1990-1995, 1997
    • (1997) Diabetes , vol.46 , pp. 1990-1995
    • Mykkänen, L.1    Haffner, S.M.2    Hales, C.N.3    Rönnemaa, T.4    Laakso, M.5
  • 6
    • 0036306096 scopus 로고    scopus 로고
    • β-cell function is the major determinant of oral glucose tolerance in four ethnic groups in the United States
    • Jensen CC, Cnop M, Hull RL, Fujimoto WY, Kahn SE, American Diabetes Association GENNID Study Group: β-Cell function is the major determinant of oral glucose tolerance in four ethnic groups in the United States. Diabetes 51:2170-2178, 2002
    • (2002) Diabetes , vol.51 , pp. 2170-2178
    • Jensen, C.C.1    Cnop, M.2    Hull, R.L.3    Fujimoto, W.Y.4    Kahn, S.E.5
  • 7
    • 0024463227 scopus 로고
    • Hyperproinsulinemia and amyloid in NIDDM: Clues to etiology of islet β-cell dysfunction?
    • Porte D Jr, Kahn SE: Hyperproinsulinemia and amyloid in NIDDM: clues to etiology of islet β-cell dysfunction? Diabetes 38:1333-1336, 1989
    • (1989) Diabetes , vol.38 , pp. 1333-1336
    • Porte Jr., D.1    Kahn, S.E.2
  • 8
    • 0028230040 scopus 로고
    • What β-cell defect could lead to hyperproinsulinemia in NIDDM? Some clues from recent advances made in understanding the proinsulin-processing mechanism
    • Rhodes CJ, Alarcon C: What β-cell defect could lead to hyperproinsulinemia in NIDDM? Some clues from recent advances made in understanding the proinsulin-processing mechanism. Diabetes 43:511-517, 1994
    • (1994) Diabetes , vol.43 , pp. 511-517
    • Rhodes, C.J.1    Alarcon, C.2
  • 9
    • 0022910962 scopus 로고
    • A sensitive radioimmunoassay for human proinsulin, with sequential use of antisera to C-peptide and insulin
    • Ward WK, Paquette TL, Frank BH, Porte D Jr: A sensitive radioimmunoassay for human proinsulin, with sequential use of antisera to C-peptide and insulin. Clin Chem 32:728-733, 1986
    • (1986) Clin Chem , vol.32 , pp. 728-733
    • Ward, W.K.1    Paquette, T.L.2    Frank, B.H.3    Porte Jr., D.4
  • 10
    • 0000476083 scopus 로고
    • Immunoassay of insulin: Two antibody system: Plasma insulin levels of normal, subdiabetic, and diabetic rats
    • Morgan DR, Lazarow A: Immunoassay of insulin: two antibody system: plasma insulin levels of normal, subdiabetic, and diabetic rats. Diabetes 12:115-126, 1963
    • (1963) Diabetes , vol.12 , pp. 115-126
    • Morgan, D.R.1    Lazarow, A.2
  • 11
    • 0016830667 scopus 로고
    • Radioimmunological determination of human C-peptide in serum
    • Heding LG: Radioimmunological determination of human C-peptide in serum. Diabetologia 11:541-548, 1975
    • (1975) Diabetologia , vol.11 , pp. 541-548
    • Heding, L.G.1
  • 12
  • 14
    • 0030662718 scopus 로고    scopus 로고
    • Release of incompletely processed proinsulin is the cause of the disproportionate proinsulinemia of NIDDM
    • Kahn SE, Halban PA: Release of incompletely processed proinsulin is the cause of the disproportionate proinsulinemia of NIDDM. Diabetes 46:1725-1732, 1997
    • (1997) Diabetes , vol.46 , pp. 1725-1732
    • Kahn, S.E.1    Halban, P.A.2
  • 15
    • 0026043872 scopus 로고
    • Prolonged maximal stimulation of insulin secretion in healthy subjects does not provoke preferential release of proinsulin
    • Nauck MA, Siegel EG, Creutzfeldt W: Prolonged maximal stimulation of insulin secretion in healthy subjects does not provoke preferential release of proinsulin. Pancreas 6:645-652, 1991
    • (1991) Pancreas , vol.6 , pp. 645-652
    • Nauck, M.A.1    Siegel, E.G.2    Creutzfeldt, W.3
  • 16
    • 0030030164 scopus 로고    scopus 로고
    • Proinsulin, C-peptide, and insulin in normal subjects during an 8-h hyperglycemic clamp
    • Hartling SG, Røder ME, Dinesen B, Binder C: Proinsulin, C-peptide, and insulin in normal subjects during an 8-h hyperglycemic clamp. Eur J Endocrinol 134:197-200, 1996
    • (1996) Eur J Endocrinol , vol.134 , pp. 197-200
    • Hartling, S.G.1    Røder, M.E.2    Dinesen, B.3    Binder, C.4
  • 19
    • 0034458043 scopus 로고    scopus 로고
    • Reduced pancreatic B-cell compensation to the insulin resistance of aging: Impact on proinsulin and insulin levels
    • Røder ME, Schwartz RS, Prigeon RL, Kahn SE: Reduced pancreatic B-cell compensation to the insulin resistance of aging: impact on proinsulin and insulin levels. J Clin Endocrinol Metab 85:2275-2280, 2000
    • (2000) J Clin Endocrinol Metab , vol.85 , pp. 2275-2280
    • Røder, M.E.1    Schwartz, R.S.2    Prigeon, R.L.3    Kahn, S.E.4
  • 21
    • 0023777821 scopus 로고
    • Improved beta-cell function after intensive insulin treatment in severe non-insulin-dependent diabetes
    • Glaser B, Leibovich G, Nesher R, Hartling S, Binder C, Cerasi E: Improved beta-cell function after intensive insulin treatment in severe non-insulin-dependent diabetes. Acta Endocrinologica 118:365-373, 1988
    • (1988) Acta Endocrinologica , vol.118 , pp. 365-373
    • Glaser, B.1    Leibovich, G.2    Nesher, R.3    Hartling, S.4    Binder, C.5    Cerasi, E.6
  • 22
    • 0030845937 scopus 로고    scopus 로고
    • Relative hyperproinsulinemia of NIDDM persists despite the reduction of hyperglycemia with insulin or sulfonylurea therapy
    • Rachman J, Levy JC, Barrow BA, Manley SE, Turner RC: Relative hyperproinsulinemia of NIDDM persists despite the reduction of hyperglycemia with insulin or sulfonylurea therapy. Diabetes 46:1557-1562, 1997
    • (1997) Diabetes , vol.46 , pp. 1557-1562
    • Rachman, J.1    Levy, J.C.2    Barrow, B.A.3    Manley, S.E.4    Turner, R.C.5


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.