Phosphatidylinositol 3-kinase regulates Ca2+ signaling in pancreatic acinar cells through inhibition of sarco(endo)plasmic reticulum Ca2+-ATPase

American Journal of Physiology - Gastrointestinal and Liver Physiology

Volumn 287, Issue 6 50-6, 2004, Pages

  Fischer, L ^a,b   Gukovskaya, A S ^a,d   Young, S H ^a   Gukovsky, I ^a   Lugea, A ^a   Buechler, P ^b   Penninger, J M ^c   Friess, H ^b   Pandol, S J ^a  

^a UNIVERSITY OF CALIFORNIA   (United States)

^b UNIVERSITY OF HEIDELBERG   (Germany)

^c ERICH SCHMID INSTITUTE OF MATERIALS SCIENCE   (Austria)

^d VETERANS AFFAIRS MEDICAL CENTER   (United States)

Author keywords

Carbachol; Cholecystokinin; Pancreas

Indexed keywords

2 MORPHOLINO 8 PHENYLCHROMONE; ADENOSINE TRIPHOSPHATASE (CALCIUM); CARBACHOL; CHOLECYSTOKININ; INOSITOL 1,4,5 TRISPHOSPHATE; INOSITOL 1,4,5 TRISPHOSPHATE RECEPTOR; PHOSPHATIDYLINOSITOL 3 KINASE; THAPSIGARGIN; TRYPSINOGEN; WORTMANNIN;

ACINAR CELL; ANIMAL CELL; ARTICLE; CALCIUM MOBILIZATION; CALCIUM SIGNALING; CALCIUM TRANSPORT; CONTROLLED STUDY; ENDOPLASMIC RETICULUM; ENZYME INHIBITION; ENZYME RELEASE; GENE DELETION; MOUSE; NONHUMAN; OSCILLATION; PANCREATITIS; PRIORITY JOURNAL; RAT;

1-PHOSPHATIDYLINOSITOL 3-KINASE; ANIMALS; CALCIUM SIGNALING; CALCIUM-TRANSPORTING ATPASES; CARBACHOL; CHOLECYSTOKININ; CHROMONES; ENZYME INHIBITORS; INOSITOL 1,4,5-TRISPHOSPHATE; MICE; MICE, INBRED C57BL; MORPHOLINES; PANCREAS; RATS; RATS, SPRAGUE-DAWLEY; SARCOPLASMIC RETICULUM CALCIUM-TRANSPORTING ATPASES; THAPSIGARGIN;

EID: 9244259154     PISSN: 01931857     EISSN: None     Source Type: Journal    
DOI: 10.1152/ajpgi.00212.2004     Document Type: Article

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