Characterization of colonic and mesenteric lymph node dendritic cell subpopulations in a murine adoptive transfer model of inflammatory bowel disease

Inflammatory Bowel Diseases

Volumn 10, Issue 6, 2004, Pages 834-847

  Karlis, John ^a   Penttila, Irmeli ^a   Tran, Tuyet B ^a   Jones, Ben ^a   Nobbs, Silvia ^b   Zola, Heddy ^a,b   Flesch, Inge E A ^a,c  

^a WOMEN S AND CHILDREN S HOSPITAL   (Australia)

^b UNIVERSITY OF ADELAIDE   (Australia)

^c MATER MEDICAL RESEARCH INSTITUTE   (Australia)

Author keywords

Autoimmunity; Colitis; Cytokines; Dendritic cells

Indexed keywords

ALPHA INTERFERON; CD11B ANTIGEN; CD40 ANTIGEN;

ADOPTIVE TRANSFER; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BONE MARROW CELL; CELL MATURATION; CELL MIGRATION; CELL SUBPOPULATION; CELLULAR IMMUNITY; CHRONIC INFLAMMATION; COLON; CONTROLLED STUDY; CROHN DISEASE; DENDRITIC CELL; ENTERITIS; EX VIVO STUDY; FEMALE; FLOW CYTOMETRY; IMMUNE RESPONSE; IMMUNOHISTOCHEMISTRY; INTESTINE MUCOSA; LYMPHOCYTE PROLIFERATION; MALE; MESENTERY LYMPH NODE; MOUSE; NONHUMAN; PATHOGENESIS; PRIORITY JOURNAL; T LYMPHOCYTE ACTIVATION; TH1 CELL; TH2 CELL; TISSUE DEGENERATION; ULCERATIVE COLITIS;

ANIMALS; COLITIS, ULCERATIVE; COLON; CROHN DISEASE; DENDRITIC CELLS; DISEASE MODELS, ANIMAL; FEMALE; FLOW CYTOMETRY; LYMPH NODES; MALE; MESENTERY; MICE; MICE, INBRED BALB C; MICE, SCID;

EID: 9144254058     PISSN: 10780998     EISSN: None     Source Type: Journal    
DOI: 10.1097/00054725-200411000-00018     Document Type: Article

References (55)

1. Banchereau J, Briere F, Caux C, et al. Immunobiology of dendritic cells. Annu Rev Immunol. 2000;18:767-811.
2. Shortman K, Liu Y-J. Mouse and human dendritic cell subtypes. Nat Rev. 2002;2:151-161.
3. Steinman RM, Hawiger D, Nussenzweig MC. Tolerogenic dendritic cells. Annu Rev Immunol. 2003;21:685-711.
4. Guermonprez P, Valladeau J, Zitvogel L. Antigen presentation and T cell stimulation by dendritic cells. Annu Rev Immunol. 2002;20:621-667.
5. Siegal FP, Kadowaki N, Shodell M, et al. The nature of the principal type 1 IFN-producing cells in human blood. Science. 1999;284:1835-1837.
6. Cella M, Jarrossay D, Facchetti F, et al. Plasmacytoid monocytes migrate to inflamed lymph nodes and produce large amounts of type 1 interferon. Nat Med. 1999;5:919-923.
7. + cells in mouse lymph nodes and spleen display characteristics of plasmacytoid dendritic cells. J Exp Med. 2001; 194:1171-1178.
8. + dendritic cells only after microbial stimulus. J Exp Med. 2002;196:1307-1319.
9. Asselin-Paturel C, Boonstra A, Dalod M, et al. Mouse type 1 IFN-producing cells are immature APCs with plasmacytoid morphology. Nat Immunol. 2001;2:1144-1150.
10. + T cells: a new role for plasmacytoid dendritic cells in adaptive immunity. Blood. 2003;101:3520-3526.
11. Björk P. The multifaceted murine plasmacytoid dendritic cell. Hum Immunol. 2002;63:1094-1102.
12. Farkas L, Beiske K, Lund-Johansen F, et al. Plasmacytoid dendritic cells (natural interferon-alpha/beta-producing cells) accumulate in cutaneous lupus erythematosus lesions. Am J Pathol. 2001;159:237-243.
13. Facchetti F, De Wolf-Peeters C, De Vos R, et al. Plasmacytoid monocytes (so-called plasmacytoid T cells) in granulomatous lymphadenitis. Hum Pathol. 1989;20:588-593.
14. Facchetti F, de Wolf-Peeters C, van den Oord JJ, et al. Plasmacytoid monocytes (so-called plasmacytoid T-cells) in Kikuchi's lymphadenitis: an immunohistologic study. Am J Clin Pathol. 1989;92:42-50.
15. high) dendritic cells in human nasal allergy. J Immunol. 2000;165:4062-4068.
16. Fiocchi C. Inflammatory bowel disease: etiology and pathogenesis. Gastroenterology. 1998;115B:182-205.
17. Papadakis KA, Targan SR. Role of cytokines in the pathogenesis of inflammatory bowel disease. Annu Rev Med. 2000;51:289-298.
18. Strober W, Fuss IJ, Blumberg RS. The immunology of mucosal models of inflammation. Annu Rev Immunol. 2002;20:495-549.
19. + T cells are important for the balance between protective and pathogenic cell-mediated immunity. J Exp Med. 1994; 179:589-600.
20. + T cells in immunodeficient, adoptive hosts depends on their state of activation, IL-12 responsiveness, and CD45RB surface phenotype. J Immunol. 1999; 162:3702-3710.
21. + T cells. Immunity 1999;11:349-358.
22. Mombaerts P, Mizoguchi E, Grusby MJ, et al. Spontaneous development of inflammatory bowel disease in T cell receptor mutant mice. Cell. 1993; 75:203-205.
23. -/- hosts. J Immunol. 2001; 166:3804-3812.
24. Neurath MF, Weigmann B, Finotto S, et al. The transcription factor T-bet regulates mucosal T cell activation in experimental colitis and Crohn's disease. J Exp Med. 2002;195:1129-1143.
25. + regulatory T cells. J Immunol. 2003; 170:3939-3943.
26. Pavli P. Murine intestinal dendritic cell isolation. In: Robinson SP and Stagg AJ, eds. Methods in Molecular Medicine. Dendritic Cell Protocols. Totowa, NJ: Humana Press, Inc; 2001:63-72.
27. Vremec D, Pooley J, Hochrein H, et al. CD4 and CD8 expression by dendritic cell subtypes in mouse thymus and spleen. J Immunol. 2000;164: 2978-2996.
28. Hochrein H, Shortman K, Vremec D, et al. Differential production of IL-12, IFN-α, and IFN-γ by mouse dendritic cell subsets. J Immunol. 2001;166:5448-5455.
29. Sugawara I, Yamada H, Mizuno S. Relative importance of STAT4 in murine tuberculosis. J Med Microbiol. 2003;52:29-34.
30. 3H-thymidine incorporation assay. J Immunol Methods. 1994;170:211-224.
31. + T cells to subepithelial dendritic cell aggregates precedes the development of colitis in a murine adoptive transfer model. Lab Invest. 2001;81:1339-1349.
32. + T cell-induced colitis. Eur J Immunol. 2003;33: 1073-1083.
33. O'Keeffe M, Hochrein H, Vremec D, et al. Effects of administration of progenipoietin 1, Flt-3 ligand, granulocyte-macrophage colonystimulating factor on dendritic cell subsets in mice. Blood. 2002;99:2122-2130.
34. Malmström V, Shipton D, Singh B, et al. CD134L expression on dendritic cells in the mesenteric lymph modes drives colitis in T cell-restored SCID mice. J Immunol. 2001;166:6972-6981.
35. Becker C, Wirtz S, Blessing M, et al. Constitutive p40 promoter activation and IL-23 production in the terminal ileum mediated by dendritic cells. J Clin Invest. 2003;112:693-706.
36. Ashcroft AJ, Cruickshank SM, Croucher PI, et al. Colonic dendritic cells, intestinal inflammation, and T cell-mediated bone destruction are modulated by recombinant osteoprotegerin. Immunity. 2003;19:849-861.
37. Stagg AJ, Hart AL, Knight SC, et al. The dendritic cell: its role in intestinal inflammation and relationship with gut bacteria. Gut. 2003;52:1522-1529.
38. Bell SJ, Rigby R, English N, et al. Migration and maturation of human colonic dendritic cells. J Immunol. 2001;166:4958-4967.
39. Iwasaki A, Kelsall BL. Freshly isolated Peyer's patch, but not spleen, dendritic cells produce interleukin 10 and induce the differentiation of T helper type 2 cells. J Exp Med. 199;1999:229-239.
40. Viney JL, Mowat AM, O'Malley JM, et al. Expanding dendritic cells in vivo enhances the induction of oral tolerance. J Immunol. 1998;160: 5815-5825.
41. Williamson E, Westrich GM, Viney JL. Modulating dendritic cells to optimize mucosal immunization protocols. J Immunol. 1999;163:3668-3675.
42. Boonstra A, Asselin-Paturel C, Gilliet M, et al. Flexibility of mouse classical and plasmacytoid-derived dendritic cells in directing T helper type 1 and 2 cell development: dependence on antigen dose and differential toll-like receptor ligation. J Exp Med. 2003;197:101-109.
43. Gilliet M, Liu YJ. Generation of human CD8 T regulatory cells by CD40 ligand-activated plasmacytoid dendritic cells. J Exp Med. 2002;195:695-704.
44. + DC, with a plasmacytoid phenotype, induce differentiation and support function of T cells with regulatory properties. Immunology. 2003;108:481-492.
45. Grewal IS, Flavell RA. CD40 and CD154 in cell-mediated immunity. Annu Rev Immunol. 1998;16:111-135.
46. Quezada SA, Jarvinen LZ, Lind EF, et al. CD40/CD154 interactions at the interface of tolerance and immunity. Annu Rev Immunol. 2004;22:307-328.
47. + T cells by blocking the CD40-CD154 interactions. J Immunol. 2000;164:6005-6014.
48. Monteleone G, Pender SLF, Wathen NC, et al. Interferon-α drives T cell-mediated immunopathology in the intestine. Eur J Immunol. 2001;31: 2247-2255.
49. Fais S, Capobianchi MR, Silvestri M, et al. Interferon expression in Crohn's disease patients: increased interferon-gamma and -alpha mRNA in the intestinal lamina propria mononuclear cells. J Interferon Res. 1994; 14:235-238.
50. Gallucci S, Lolkema M, Matzinger P. Natural adjuvants: endogenous activators of dendrific cells. Nat Med. 1999;5:1249-1255.
51. Montoya M, Schiavoni G, Mattei F, et al. Type I interferons produced by dendritic cells promote their phenotypic and functional activation. Blood. 2002;99:3263-3271.
52. Mohty M, Vialle-Castellano A, Nunes JA, et al. IFN-α skews monocyte differentiation into toll-like receptor 7-expressing dendritie cells with potent functional activities. J Immunol. 2003;171:3385-3393.
53. + DC1 precursors. Blood. 2003; 101:1453-1459.
54. del Hoyo GM, Martin P, Vargas HH, et al. Characterization of a common precursor population for dendritic cells. Nature. 2002;415:1043-1047.
55. - dendritic cell populations in the colonic mucosa of patients with Crohn's disease. Eur J Immunol. 2003;33:143-151.