Sorting and targeting of melanosomal membrane proteins: Signals, pathways, and mechanisms

Pigment Cell Research

Volumn 13, Issue 3, 2000, Pages 128-134

  Setaluri, Vijayasaradhi ^a  

^a WAKE FOREST SCHOOL OF MEDICINE   (United States)

Author keywords

Di leucine motif; Endoplasmic reticulum quality control; Endosomes; Melanocytes; Pigmentation; Tyrosinase; Tyrosinase related proteins

Indexed keywords

MEMBRANE PROTEIN;

AMINO ACID SEQUENCE; ANIMAL; ENDOPLASMIC RETICULUM; ENDOSOME; GOLGI COMPLEX; HUMAN; MELANOSOME; METABOLISM; MOLECULAR GENETICS; PHYSIOLOGY; REVIEW; SEQUENCE HOMOLOGY; SIGNAL TRANSDUCTION; TRANSPORT AT THE CELLULAR LEVEL;

AMINO ACID SEQUENCE; ANIMALS; BIOLOGICAL TRANSPORT; ENDOPLASMIC RETICULUM; ENDOSOMES; GOLGI APPARATUS; HUMANS; MELANOSOMES; MEMBRANE PROTEINS; MOLECULAR SEQUENCE DATA; SEQUENCE HOMOLOGY, AMINO ACID; SIGNAL TRANSDUCTION;

ANIMALIA; MURINAE;

EID: 0034046801     PISSN: 08935785     EISSN: None     Source Type: Journal    
DOI: 10.1034/j.1600-0749.2000.130302.x     Document Type: Review

References (59)

1. Orlow SJ. Melanosomes are specialized members of the lysosomal lineage of organelles. J Invest Dermatol 1995;104:1-5
2. Orlow SJ. The biogenesis of melanosomes. In: Nordlund JM, Biossy RE, Hearing VJ, King RA, Ortonne JP. The Pigmentary System: Physiology and Pathophysiology. New York: Oxford University Press; 1998. pp. 97-106
3. Johnson AE, van Waes MA. The translocon: A dynamic gateway at the ER membrane. Ann Rev Cell Dev Biol 1999;15:799-842
4. Allan BB, Balch WE. Protein sorting by directed maturation of Golgi compartments. Science 1999;285:63-66
5. Kirchhausen T. Adaptors for clathrin-mediated traffic. Ann Rev Cell Dev Biol 1999;15:705-732
6. Bonifacino JS, Weissman AM. Ubiqitin and the control of protein fate in the secretory and endocytic pathways. Ann Rev Cell Dev Biol 1998;14:19-58
7. Hughes EA, Hammond C, Cresswell P. Misfolded major histo-compatibility complex class I heavy chains are translocated into the cytoplasm and degraded by the proteosome. Proc Natl Acad Sci USA 1997;94:1896-1901
8. Tortorella D, Story CM, Huppa JB, Wiertz EJHJ, Jones TR, Ploegh HL. Dislocation of type I membrane proteins from the ER to the cytosol is sensitive to changes in redox potential. J Cell Biol 1998;142:365-376
9. Halaban R, Pomerantz SH, Marshall S, Lambert DT, Lerner AB. Regulation of tyrosmase in human melanocytes grown in culture. J Cell Biol 1983;97:480-488
10. Vijayasaradhi S, Doskoch PM, Houghton AN. Biosynthesis and intracellular movement of the melanosomal membrane glycoprotein gp75, the human b (Brown) locus product. Exp Cell Res 1991;196:233-240
11. Halaban R, Cheng E, Zhang Y, Moellmann G, Hanlon D, Michalak M, Herbert DN. Aberrant retention of tyrosinase in the endoplasmic reticulum mediates accelerated degradation of the enzyme and contributes to the dedifferentiated phenotype of amelanotic melanoma cells. Proc Natl Acd. Sci USA 1997;94:6210-6215
12. Kato F, Jimbow K. Interaction of calnexin and calreticulin is required for acid-resistant structure and correct processing of tyrosinase-related protein from ER to melanosomes. J Invest Dermatol 1998;110:568-572
13. Jimenez M, Kameyama K, Maloy WL, Tomita Y, Hearing VJ. Mammalian tyrosinase: Biosynthesis, processing, and modulation by melanocyte-stimulating hormone. Proc Natl Acad Sci USA 1988;85:3830-3834
14. Teasdale RD, Jackson MR. Signal-mediated sorting of membrane proteins between the endoplasmic reticulum and the Golgi apparatus. Ann Rev Cell Bio Dev Biol 1996;12:27-55
15. Campbell JL, Schekman R. Selective packaging of cargo molecules into endoplasmic reticulum-derived COPII vesicles. Proc Natl Acad Sci USA 1997;94:837-842
16. Kuehn MJ, Herrmann JM, Schekman R. COPII-cargo interactions direct protein sorting into ER-derived transport vesicles. Nature 1998;391:187-190
17. Nishimura N, Balch WE. A di-acidic signal required for selective export from the endoplasmic reticulum. Science 1997;277:556-558
18. Xu Y, Setaluri V, Houghton AN. The cytoplasmic tail of the mouse brown locus product determines the intracellular stability and export from the endoplasmic reticulum. J Invest Dermatol 1998;110:324-331
19. Wang RF, Parkhurst MR, Kawakami PF, Robbins PF, Rosenberg SA. Utilization of an alternative open reading frame of a normal gene in generating a novel human cancer antigen. J Exp Med 1996;183:1131-1140
20. Roux L, Lloyd KO. Glycosylation characteristics of pigmentation-associated antigen (GP75): An intracellular glycoprotein of human melanocytes and malignant melanomas. Arch Biochem Biophys 1986;251:87-96
21. Le Borgne R, . Hoflack B. Protein transport from the secretory to the endocytic pathway in mammalian cells. Biochim Biophys Acta 1998;140:195-209
22. Barriocanal JG, Bonifacino JS, Yuan L, Sandoval IV. Biosynthesis, glycosylation, movement through the Golgi system, and transport to lysosomes by an N-linked carbohydrate-independent mechanism of three lysosomal integral membrane proteins. J Biol Chem 1986;261:16755-16763
23. Kirchhausen T, Bonifacino JS, Riezman H. Linking cargo to vesicle formation: Receptor tail interactions with coat proteins. Curr Opin Cell Biol 1996;9:488-495
24. Williams MA, Fukuda M. Accumulation of membrane glycoproteins in lysosomes requires a tyrosine residue at a particular position in the cytoplasmic tail. J Cell Biol 1991;111:955-966
25. Ogata S, Fukuda M. Lysosomal targeting of LIMPII membrane glycoprotein requires a novel leu-ile motif at a particular position in its cytoplasmic tail. J Biol Chem 1994;269:5210-5217
26. Vijayasaradhi S, Xu Y, Bouchard B, Houghton AN. Intracellular sorting and targeting of melanosomal membrane protein: Identification of signals for the sorting of the human brown locus protein, gp75. J Cell Biol 1995;130:807-820
27. Xu Y, Setaluri V, Takechi Y, Houghton AN. Sorting and secretion of a melanosome membrane protein, gp75/TRP-1. J Invest Dermtol 1997;109:788-795
28. Rinchik EM, Bultman SJ, Hrsthemke B, Lee ST, Strunk KM, Spritz RA, Avidamo KM, Jong MTC, Nicholls RD. A gene for the mouse pink-eyed dilution locus and for human type II oculocutaneous albinism. Nature 1993;361:72-76
29. Rosenblat S, Durham-Pierre D, Gardnerm JM, Nakatsu Y, Brilliant MH, Orlow SJ. Identification of a melanosomal membrane protein encoded by the pink-eyed dilution (type II oculocutaneous albinism) gene. Proc Natl Acad Sci USA 1994;91:12071-12075
30. Chintamaneni CD, Halaban R, Kobayashi Y, Witkop CJ, Kwon BS. A single base insertion in the putative transmembrane domain of tyrosinase gene as a cause for tyrosinase-negative oculocutaneous albinism. Proc Natl Acad Sci USA 1991;88:5272-5276
31. P) mutation. Exp Eye Res 1995;61:599-607
32. Simmen T, Schmidt A, Hunziker W, Beerman F. The tyrosianse tail mediates sorting to the lysosomal compartment in MDCK cells via a di-leucine and a tyrosine-based signal. J Cell Sci 1999;112:45-53
33. Kantheti P, Qiao X, Diaz ME, Peden AA, Meyer GE, Carskadon SL, Kapfhamer D, Sufalko D, Robinson MS, Noebels JL, Burmeister M. Mutation in AP-3 delta in the mocha mouse links endosomal transport to storage deficiency in platelets, melanosomes and synaptic vesicles. Neuron 1998;21:111-122
34. Feng GH, Bailin T, Oh J, Spritz RA. Mouse pale ear (pe) is homologous to human Hermansky-Pudlak syndrome and contains an AT-AC intron. Hum Mol Genet 1997;6:793-797
35. Dell'Angelica EC, Shotelersuk V, Aguilar RC, Gahl WA, Bonifacino JS. Altered trafficking of lysosomal proteins in Hermansky-Pudlak syndrome due to mutations in the beta3A subunit of the AP-3 adaptor. Mol Cell 1999;3:1-20
36. Spritz RA. Hermansky-Pudalk syndrome and pale ear: melanosome-making for the millennium. Pig Cell Res 2000; 13, in press.
37. Ohno H, Fournier MC, Poy G, Bonifacino JS. Structural determinants of interaction of tyrosine-based sorting signals with the adaptor medium chains. J Biol Chem 1996;271:29009-29015
38. Ohno H, Aguilar RC, Yeh D, Taura D, Saito T, Bonifacino JS. The medium subunits of adaptor complexes recognize distinct but overlapping sets of tyrosine-based sorting signals. J Biol Chem 1998;273:25915-25921
39. Schiaffino MV, Baschirotto C, Pellegrini G, Motalti S, Tacchetti C, De Luca M, Ballabio A. The ocular albinism type I gene product is a membrane glycoprotein localized to melanosome. Proc Natl Acad Sci USA 1996;93:9055-9060
40. Letourner F, Klausner RD. A novel di-leucine motif and a tyrosine based motif independently mediate lysosomal targeting and endocytosis of CD3 chains. Cell 1992;69:1143-1157
41. Pelchen-Mathews A, Boulet I, Littman DR, Fagard R, Marsh M. The protein tyrosine kinase p561ck inhibits CD4 endocytosis by preventing entry of CD4 into coated pits. J Cell Biol 1992;117:279-290
42. Subramani S. Convergence of model systems for peroxisome biogenesis. Curr Opin Cell Biol 1996;8:513-518
43. Hirst J, Robinson MS. Clathrin and adaptors. Biochim Biophys Acta 1998;1404:173-193
44. Honing S, Sandoval IV, von Figura K. A di-leucine-based motif in the cytoplasmic tail of LIMP-II and tyrosinase mediates selective binding of AP-3. EMBO J 1998;17:1304-1314
45. Odorizzi G, Cowles CR, Emr SD. The AP-3 complex: A coat of many colours. Trends Cell Biol 1998;8:282-288
46. Stinchcombe J, Griffiths GM. Regulated secretion from hemopoietic cells. J Cell Biol 1999;147:1-5
47. Wang S, Bartido S, Yang G, Moroi Y, Panageas KS, Lewis JJ, Houghton AN. A role for a melanosome transport signal in accessing the MHC class II presentation pathway and in eliciting CD4 T cell responses. J Immunol 1999;163:5820-5826
48. Diment S, Eidelman M, Rodriguez GM, Orlow SJ. Lysosomal hydrolases are present in melanosomes and are elevated in melanizing cells. J Biol Chem 1995;270:4213-4215
49. Mellman I. Endocytosis and molecular sorting. Ann Rev Cell Dev Biol 1996;12:575-625
50. Burkhardt JK, Wiebel FA, Hester S, Argon Y. The giant organelles in beige and Chediak-Higashi fibroblasts are derived from late endosomes and mature lysosomes. J Exp Med 1993;178:1845-1856
51. Baetz KS, Isaaz S, Griffiths GM. Loss of cytotoxic T lymphocytes function in Chediak-Higashi syndrome arises from a secretory defect that prevents lytic granule exocytosis. J Immunol 1995;154:6122-6131
52. Barbosa MD, Nguyen QA, Tchernev VT, Ashley JA, Detter SM, Blaydes SJ, Brandt D, Chotai C, Hodgman RC, Solari M, Lovett M. Identification of the homologous beige and Chediak-Higashi syndrome genes. Nature 1999;382:262-265
53. Perou CM, Moore KJ, Nagle DL, Misumi EA, Woolf SH, McGrail L, Holmgren TH, Brody BJ, Dussault Jr CA, Monroe CA, Duyk GM, Pryor RJ, Li L, Justice MJ, . Kaplan J. Identification of the murine beige gene by YAC complementation and positional cloning. Nature Genet 1996;13:303-308
54. Perou CM, Leslie JD, Green W, Li L, Ward DM, Kaplan J. The Beige/Chediak-Higashi syndrome gene encodes a widely expressed cytosolic protein. J Biol Chem 1997;272:29790-29794
55. Spritz RA. Genetic defects in Chediak-Higashi syndrome and in the beige mouse. J Clin Immunol 1998;18:97-105
56. Calvo PA, Frank DW, Bieler BM, Berson JF, Marks MS. A cytoplasmic sequence in human tyrosinase defines a second class of di-leucine-based sorting signals for late endosomal and lysosomal delivery. J Biol Chem 1999;274:12780-12789
57. Pfeffer SR. Transport vesicle docking: SNAREs and associates. Ann Rev Cell Biol Dev Biol 1996;12:441-462
58. Hannah MJ, Schmidt AA, Huttner WB. Synaptic vesicle biogenesis. Ann Rev Cell Biol Dev Biol 1999;15:733-798
59. Huang L, Kuo Y-M, Gitscher J. The pallid gene encodes a novel, syntaxin 13-interacting protein involved in platelet storage pool deficiency. Nature Genet 1999;23:329-332