Review of microdialysis in brain tumors, from concept to application: First annual Carolyn Frye-Halloran symposium

Neuro-Oncology

Volumn 6, Issue 1, 2004, Pages 65-74

  Benjamin, Ramsis K ^a,n   Hochberg, Fred H ^a   Fox, Elizabeth ^b   Bungay, Peter M ^c   Elmquist, William F ^d   Stewart, Clinton F ^e   Gallo, James M ^f   Collins, Jerry M ^g   Pelletier, Robert P ^h   de Groot, John F ⁱ   Hickner, Robert C ^j   Cavus, Idil ^k   Grossman, Stuart A ^l   Colvin, O Michael ^m  

^a MASSACHUSETTS GENERAL HOSPITAL   (United States)

^b NATIONAL CANCER INSTITUTE   (United States)

^c NATIONAL INSTITUTES OF HEALTH   (United States)

^d UNIVERSITY OF MINNESOTA   (United States)

^e ST JUDE CHILDREN S RESEARCH HOSPITAL   (United States)

^f FOX CHASE CANCER CENTER   (United States)

^g CENTER FOR DRUG EVALUATION AND RESEARCH   (United States)

^h CMA Microdialysis   (United States)

ⁱ UNIVERSITY OF TEXAS   (United States)

^j EAST CAROLINA UNIVERSITY   (United States)

^k YALE UNIVERSITY   (United States)

^l JOHNS HOPKINS UNIVERSITY   (United States)

^m DUKE UNIVERSITY MEDICAL CENTER   (United States)

ⁿ CAROLINA NEUROSURGERY AND SPINE ASSOCIATES   (United States)

more..

Author keywords

[No Author keywords available]

Indexed keywords

ALPHA INTERFERON; ANGIOGENESIS INHIBITOR; ANTINEOPLASTIC AGENT; CISPLATIN; CYTOKINE; CYTOSTATIC AGENT; CYTOTOXIC AGENT; FUMAGILLOL CHLOROACETYLCARBAMATE; INTERLEUKIN 1BETA; INTERLEUKIN 6; METHOTREXATE; NERVE GROWTH FACTOR; ONCOPROTEIN; PLATINUM; PLATINUM DERIVATIVE; SEMAXANIB; TEMOZOLOMIDE; ZIDOVUDINE;

BRAIN HEMORRHAGE; BRAIN INJURY; BRAIN TISSUE; BRAIN TUMOR; CANCER CENTER; CANCER THERAPY; CATHETER; DRUG BLOOD LEVEL; DRUG BRAIN LEVEL; DRUG DELIVERY SYSTEM; DRUG METABOLISM; DRUG MONITORING; DRUG PENETRATION; EPILEPSY; EXTRACELLULAR FLUID; GENERAL HOSPITAL; HUMAN; INTENSIVE CARE UNIT; INTERSTITIAL FLUID; MEDICAL INSTRUMENTATION; MEDICAL SPECIALIST; MEDICAL TECHNOLOGY; MEMBRANE PERMEABILITY; MICRODIALYSIS; MOLECULAR PROBE; NEUROLOGY; NONHUMAN; ONCOLOGY; REVIEW; SAMPLING; SYMPOSIUM; UNITED STATES; VASOSPASM;

ANIMALS; ANTINEOPLASTIC AGENTS; BRAIN NEOPLASMS; CLINICAL TRIALS, PHASE I; DRUG EVALUATION, PRECLINICAL; HUMANS; MICRODIALYSIS;

EID: 9144233488     PISSN: 15228517     EISSN: None     Source Type: Journal    
DOI: 10.1215/S1152851703000103     Document Type: Review

References (66)

1. Abi-Saab, W.M., Maggs, D.G., Jones, T., Jacob, R., Srihari, V., Thompson, J., Kerr, D., Leone, P., Krystal, J.H., Spencer, D.D., During, M.J., and Sherwin, R.S. (2002) Striking differences in glucose and lactate levels between brain extracellular fluid and plasma in conscious human subjects: Effects of hyperglycemia and hypoglycemia. J. Cereb. Blood Flow Metab. 22, 271-279.
2. Alessandri, B., Doppenberg, E., Bullock, R., Woodward, J., Choi, S., Koura, S., and Young, H.F. (1999a) Glucose and lactate metabolism after severe human head injury: Influence of excitatory neurotransmitters and injury type. Acta Neurochir. Suppl. (Wien) 75, 21-24.
3. Alessandri, B., Doppenberg, E., Zauner, A., Woodward, J., Choi, S., and Bullock, R. (1999b) Evidence for time-dependent glutamate-mediated glycolysis in head-injured patients: A microdialysis study. Acta Neurochir. Suppl. (Wien) 75, 25-28.
4. Bobo, R.H., Laske, D.W., Akbasak, A., Morrison, P.F., Dedrick, R.L., and Oldfield, E.H. (1994) Convection-enhanced delivery of macromolecules in the brain. Proc. Nat. Acad. Sci. USA 91, 2076-2080.
5. Boiardi, A., Eoli, M., Pozzi, A., Salmaggi, A., Broggi, G., and Silvani, A. (1999) Locally delivered chemotherapy and repeated surgery can improve survival in glioblastoma patients. Ital. J. Neurol. Sci. 20, 43-48.
6. Brada, M., and Shape, G. (1996) Chemotherapy of high grade gliomas: Beginning of a new era or the end of the old? Eur. J. Cancer 32A, 2193-2194 (editorial).
7. Brada, M., and Yung, W.K. (2000) Clinical trial end points in malignant glioma: Need for effective trial design strategy. Semin. Oncol. 27, 11-19 (suppl).
8. Bungay, P.M., Dedrick, R.L., Fox, E., and Balis, F.M. (2001) Probe calibration in transient microdialysis in vivo. Pharm. Res. 18, 361-366.
9. Cairncross, G., Swinnen, L., Bayer, R., Rosenfeld, S., Salzman, D., Paleologos, N., Kaminer, L., Forsyth, P., Stewart, D., Peterson, K., Hu, W., Macdonald, D., Ramsay, D., and Smith, A., for the Oligodendroglioma Study Group (2000) Myeloablative chemotherapy for recurrent aggressive oligodendroglioma. Neuro-Oncol. 2, 114-119.
10. Chabner, B.A., Boral, A.L., and Multani, P. (1998) Translational research: Walking the bridge between idea and cure - Seventeenth Bruce F. Cain Memorial Award Lecture. Cancer Res. 58, 4211-4216.
11. DeAngelis, L.M. (2001) Brain tumors. N. Engl. J. Med. 344, 114-123.
12. de Lang, E.C., de Vries, J.D., Zurcher, C., Danhof, M., de Boer, A.G., and Breimer, D.D. (1995a) The use of intracerebral microdialysis for the determination of pharmacokinetic profiles of anticancer drugs in tumor-bearing rat brain. Pharm. Res. 12, 1924-1931.
13. de Lang, E.C., Danhof, M., Zurcher, C., de Boer, A.G., and Breimer, D.D. (1995b) Repeated microdialysis perfusions: Periprobe tissue reactions and BBB permeability. Brain Res. 702, 261-265.
14. de Lang, E.C., Danhof, M., de Boer, A.G., and Breimer, D.D. (1997) Methodological considerations of intracerebral microdialysis in pharmacokinetic studies on drug transport across the blood-brain barrier. Brain Res. Rev. 25, 27-49.
15. De Micheli, E., Alfieri, A., Pinna, G., Bianchi, L., Colivicchi, M.A., Melani, A., Pedata, F., Della Corte, L., and Bricolo, A. (2000) Extracellular levels of taurine in tumoral, peritumoral, and normal brain tissue in patients with malignant glioma: An intraoperative microdialysis study. Adv. Exp. Med. Biol. 483, 621-625.
16. Devineni, D., Klein-Szanto, A., and Gallo, J.M. (1996a) Uptake of temozolomide in a rat glioma model in the presence and absence of the angiogenesis inhibitor TNP-470. Cancer Res. 56, 1983-1987.
17. Devineni, D., Klein-Szanto, A., and Gallo, J.M. (1996b) In vivo microdialysis to characterize drug transport in brain tumors: Analysis of methotrexate uptake in rat glioma-2 (RG-2)-bearing rats. Cancer Chemother. Pharmacol. 38, 499-507.
18. Disabato, J.A., Handler, M.H., Strain, J.D., Fleitz, J.M., and Foreman, N.K. (1999) Successful use of intracavitary bleomycin for low-grade astrocytoma tumor cyst. Ped. Neurosurg. 31, 246-250.
19. Dropcho, E.J. (2001) Novel chemotherapeutic approaches to brain tumors. Hematol. Oncol. Clin. North Am. 15, 1027-1052.
20. Dukic, S., Kaltenbach, M.L., Gourdier, B., Marty, H., and Vistelle, R. (1998) Determination of free extracellular levels of methotrexate by microdialysis in muscle and solid tumor of the rabbit. Pharm. Res. 15, 133-138.
21. During, M.J., and Spencer, D.D. (1993) Extracellular hippocampal glutamate and spontaneous seizure in the conscious human brain. Lancet 341, 1607-1610.
22. Dykstra, K.H., Hsiao, J.K., Morrison, P.F., Bungay, P.M., Mefford, I.N., Scully, M.M., and Dedrick, R.L. (1992) Quantitative examination of tissue concentration profiles associated with microdialysis. J. Neurochem. 58, 931-940.
23. Elmquist, W.F., and Sawchuk, R.J. (1997) Application of microdialysis in pharmacokinetic studies. Pharm. Res. 14, 267-288.
24. Fox, E., Curt, G.A., and Balls, F.M. (2002a) Clinical trial design for target-based therapy. Oncologist 7, 401-409.
25. Fox, E., Bungay, P.M., Bacher, J., McCully, C.L., Dedrick, R.L., and Balis, F.M. (2002b) Zidovudine concentration in brain extracellular fluid measured by microdialysis: Steady-state and transient results in rhesus monkey. J. Pharmacol. Exp. Ther. 301, 1003-1011.
26. Gibaldi, M., and Perrier, D. (1982) Pharmacokinetics, 2nd ed. New York: Marcel Dekker, Inc.
27. Gopinath, S.P., Valadka, A.B., Goodman, J.C., and Robertson, C.S. (2002) Extracellular glutamate and aspartate in head injured patients. Acta Neurochir. Suppl. 76, 437-438.
28. Graham, M.L., Herndon, J.E., 2nd, Casey, J.R., Chaffee, S., Ciocci, G.H., Krischer, J.P., Kurtzberg, J., Laughlin, M.J., Longee, D.C., Olson, J.F., Paleologus, N., Pennington, C.N., and Friedman, H.S. (1997) High-dose chemotherapy with autologous stem-cell rescue in patients with recurrent and high-risk pediatric brain tumors. J. Clin. Oncol. 15, 1814-1823.
29. Groothuis, D.R., Ward, S., Schlageter, K.E., Itskovich, A.C., Schwerin, S.C., Allen, C.V., Dills, C., and Levy, R.M. (1998) Changes in blood-brain barrier permeability associated with insertion of brain cannulas and microdialysis probes. Brain Res. 803, 218-230.
30. Haines, S.J. (2002) Moving targets and ghosts of the past: Outcome measurement in brain tumour therapy. J. Clin. Neurosci. 9, 109-112.
31. Hargrave, D.R., Bouffet, E., Gammon, J., Tariq, N., Grant, R.M., and Baruchel, S. (2002) Phase I study of fotemustine in pediatric patients with refractory brain tumors. Cancer 95, 1294-1301.
32. Haroun, R.I., Clatterbuck, R.E., Gibbons, M.C., Burger, P.C., Parker, R., Fruehauf, J.P., and Brem, H. (2002) Extreme drug resistance in primary brain tumors: In vitro analysis of 64 resection specimens. J. Neurooncol. 58, 115-123.
33. Hlatky, R., Furuya, Y., Valadka, A.B., Goodman, J.C., and Robertson, C.S. (2002) Comparison of microdialysate arginine and glutamate levels in severely head-injured patient. Acta Neurochir. Suppl. 81, 347-349.
34. Hutchinson, P.J., Gupta, A.K., Fryer, T.F., Al-Rawi, P.G., Chatfield, D.A., Coles, J.P., O'Connell, M.T., Kett-White, R., Minhas, P.S., Aigbirhio, F.I., Clark, J.C., Kirkpatrick, P.J., Menon, D.K., and Pickard, J.D. (2002) Correlation between cerebral blood flow, substrate delivery, and metabolism in head injury: A combined microdialysis and triple oxygen positron emission tomography study. J. Cereb. Blood Flow Metab. 22, 735-745.
35. Kellie, S.J., Barbaric, D., Koopmans, P., Earl, J., Carr, D.J., and de Graaf, S.S. (2002) Cerebrospinal fluid concentrations of vincristine after bolus intravenous dosing: A surrogate marker of brain penetration. Cancer 94, 1815-1820.
36. Kennedy, R.T., Watson, C.J., Haskins, W.E., Powell, D.H., and Strecker, R.E. (2002) In vivo neurochemical monitoring by microdialysis and capillary separations. Curr. Opin. Chem. Biol. 6, 659-665.
37. Koopmans, P.P. (2002) Clinical endpoints in trials of drugs for cancer: Time for a rethink? B.M.J. 324, 1389-1391.
38. 111In-labelled bleomycin complex for the differentiation of high- and low-grade gliomas. Nuclear Med. Commun. 20, 145-152.
39. Kraemer, D.F., Fortin, D., and Neuwelt, E.A. (2002) Chemotherapeutic dose intensification for treatment of malignant brain tumors: Recent developments and future directions. Curr. Neurol. Neurosci. Rep. 2, 216-224.
40. Lesniak, M.S., Langer, R., and Brem, H. (2001) Drug delivery to tumors of the central nervous system. Curr. Neurol. Neurosci. Rep. 1, 210-216.
41. Lonnroth, P., Jansson, P.A., and Smith, U. (1987) A microdialysis method allowing characterization of intracellular water space in humans. Am. J. Physiol. 253, E228-E231.
42. Lowe, E., and Balis, F.M. (2001) Dose-effect and concentration-effect analysis. In: Atkinson, A.J., Jr., Daniels, C.E., Deddrick, R.L., Grudzinskas, C.V., and Markey, S.P. (Eds.), Principles of Clinical Phamacology, San Diego, Calif.: Academic Press. pp. 235-244.
43. Ma, J., Pulfer, S., Li, S., Chu, J., Reed, K., and Gallo, J.M. (2001) Pharmacodynamic-mediated reduction of temozolomide tumor concentrations by the angiogenesis inhibitor TNP-470. Cancer Res. 61, 5491-5498.
44. Ma, J., Li, S., Reed, K., Guo, P., and Gallo, J.M. (2003) Pharmacodynamic-mediated effects of the angiogenesis inhibitor SU5416 on the tumor disposition of temozolomide (TMZ) in subcutaneous and intracerebral human glioma xenograft models. J. Pharmacol. Exp. Ther. 305, 833-839.
45. Marion, D.W., Puccio, A., Wisniewski, S.R., Kochanek, P., Dixon, C.E., Bullian, L., and Carlier, P. (2002) Effect of hyperventilation on extracellular concentrations of glutamate, lactate, pyruvate, and local cerebral blood flow in patients with severe traumatic brain injury. Crit. Care Med. 30, 2619-2625.
46. Meixensberger, J., Kunze, E., Barcsay, E., Vaeth, A., and Roosen, K. (2001) Clinical cerebral microdialysis: Brain metabolism and brain tissue oxygenation after acute brain injury. Neurol. Res. 23, 801-806.
47. Meyerson, B.A., Linderoth, B., Karlsson, H., and Ungerstect, U. (1990) Microdialysis in the human brain: Extracellular measurements in the thalamus of parkinsonian patients. Life Sci. 46, 301-308.
48. Morgan, M.E., Singhal, D., and Anderson, B.D. (1996) Quantitative assessment of blood-brain barrier damage during microdialysis. J. Pharmacol. Exp. Ther. 277, 1167-1176.
49. Muller, M. (2000) Microdialysis in clinical drug delivery studies. Adv. Drug Deliv. Rev. 45, 255-269.
50. Muller, M., Mader, R.M., Steiner, B., Steger, G.G., Jansen, B., Gnant, M., Helbich, T., Jakesz, R., Eichler, H.G., and Blochl-Daum, B. (1997) 5-Fluorouracil kinetics in the interstitial tumor space: Clinical response in breast cancer patients. Cancer Res. 57, 2598-2601.
51. Nilsson, O.G., Saveland, H., Boris-Moller, F., Brandt, L., and Wieloch, T. (1996) Increased levels of glutamate in patients with subarachnoid haemorrhage as measured by intracerebral microdialysis. Acta Neurochir. Suppl. (Wien) 67, 45-47.
52. Oertel, M., Kelly D.F., Lee, J.H., McArthur, D.L., Glenn, T.C., Vespa, P., Boscardin, W.J., Hovda, D.A., and Martin, N.A. (2002) Efficacy of hyperventilation, blood pressure elevation, and metabolic suppression therapy in controlling intracranial pressure after head injury. J. Neurosurg. 97, 1045-1053.
53. Persson, L., and Hillered, L. (1992) Chemical monitoring of neurosurgical intensive care patients using intracerebral microdialysis. J. Neurosurg. 76, 72-80.
54. Planas, A.M., Justicia, C., Sole, S., Friguls, B., Cervera, A., Adell, A., and Chamorro, A. (2002) Certain forms of matrix metalloproteinase-9 accumulate in the extracellular space after microdialysis probe implantation and middle cerebral artery occlusion/reperfusion. J. Cereb. Blood Flow Metab. 22, 918-925.
55. Rall, D.P., and Zubrod, C.G. (2000) Mechanisms of drug absorption and excretion: Passage of drugs in and out of the central nervous system. In: Abeloff, M.D. (Ed.), Clinical Oncology, 2nd ed., New York: Churchill Livingstone, pp. 109-128.
56. Roche, H., Cure, H., Adenis, A., Fargeot, P., Terret, C., Lentz, M.A., Madelmont, J.C., Fumoleau, P., Hanausk, A., and Chollet, P. (2000) Phase II trial of cystemustine, a new nitrosourea, as treatment of high-grade brain tumors in adults. J. Neurooncol. 49, 141-145.
57. Roslin, M., Henriksson, R., Bergström, P., Ungerstedt, U., and Bergenheim, T.A. (2003) Baseline levels of glucose metabolites, glutamate and glycerol in malignant glioma assessed by stereotactic microdialysis. J. Neurooncol. 61, 151-160.
58. 111In-labeled bleomycin in patients with brain tumors: Compartmental vs. non-compartmental models. Ann. Nuclear Med. 12, 313-321.
59. Sun, H., Bungay, P.M., and Elmquist, W.F. (2001) Effect of capillary efflux transport inhibition on the determination of probe recovery during in vivo microdialysis in the brain. J. Pharmacol. Exp. Ther. 297, 991-1000.
60. Tokunaga, Y., Nakashima, M., Sasaki, H., Tomiyama, N., Nakashima, M.N., Ichikawa, M., Kaminogo, M., and Shibata, S. (2000) Local distribution into brain tumor and pharmacokinetics of 4-pyridoxate diammine hydroxy platinum, a novel cisplatin derivative, after intracarotid administration in rats with 9L malignant glioma: Simultaneous brain microdialysis study. Biol. Pharm. Bull. 23, 1491-1496.
61. Ungerstedt, U., and Pycock, C. (1974) Functional correlates of dopamine neurotransmission. Bull. Schweizerischen Akad. Med. Wiss. 30, 44-55.
62. Vespa, P., Prins, M., Ronne-Engstrom, E., Caron, M., Shalmon, E., Hovda, D.A., Martin, N.A., and Becker, D.P. (1998) Increase in extracellular glutamate caused by reduced cerebral perfusion pressure and seizures after human traumatic brain injury: A microdialysis study. J. Neurosurg. 89, 971-982.
63. Vespa, P.M., McArthur, D., O'Phelan, K., Glenn, T., Etchepare, M., Kelly, D., Bergsneider, M., Martin, N.A., and Hovda, D.A. (2003) Persistently low extracellular glucose correlates with poor outcome 6 months after human traumatic brain injury despite a lack of increased lactate: A microdialysis study. J. Cereb. Blood Flow Metab. 23, 865-877.
64. Wang, Y., Wong, S.L., and Sawchuk, R.J. (1993) Microdialysis calibration using retrodialysis and zero-net flux: Application to a study of the distribution of zidovudine to rabbit cerebrospinal fluid and thalamus. Pharm. Res. 10, 1411-1419.
65. Winter, C.D., Iannotti, F., Pringle, A.K., Trikkas, C., Clough, G.F., and Church, M. K. (2002) A microdialysis method for the recovery of IL-1beta, IL-6 and nerve growth factor from human brain in vivo. J. Neurosci. Methods 119, 45-50.
66. Zamboni, W.C., Gervais, A.C., Egorin, M.J., Schellens, J.H., Hamburger, D.R., Delauter, B.J., Grim, A., Zuhowski, E.G., Joseph, E., Pluim, D., Potter, D.M., and Eiseman, J.L. (2002) Inter- and intratumoral disposition of platinum in solid tumors after administration of cisplatin. Clin. Cancer Res. 8, 2992-2999.