Increased Levels of Glutamate in Patients with Subarachnoid Haemorrhage as Measured by Intracerebral Microdialysis

Acta Neurochirurgica, Supplement

Volumn 1996, Issue 67, 1996, Pages 45-47

  Nilsson, O G ^a   Saveland H ^a   Boris Moller F ^a   Brandt, L ^a   Wieloch, T ^a  

^a LUND UNIVERSITY HOSPITAL   (Sweden)

Author keywords

Aneurysmal subarachnoid haemorrhage; Glutamate; Intracerebral microdialysis; Ischemia

Indexed keywords

GLUTAMIC ACID;

ADULT; ARTICLE; CASE REPORT; FEMALE; FRONTAL LOBE; HUMAN; MALE; METABOLISM; MICRODIALYSIS; MIDDLE AGED; SUBARACHNOID HEMORRHAGE; TEMPORAL LOBE;

ADULT; FEMALE; FRONTAL LOBE; GLUTAMIC ACID; HUMANS; MALE; MICRODIALYSIS; MIDDLE AGED; SUBARACHNOID HEMORRHAGE; TEMPORAL LOBE;

EID: 0030332028     PISSN: 00651419     EISSN: None     Source Type: Book Series    
DOI: 10.1007/978-3-7091-6894-3_10     Document Type: Article

References (10)

1. Benveniste H, Drejer J, Schousboe A, Diemer NH (1984) Elevation of the extracellular concentrations of glutamate and aspartate in rat hippocampus during transient cerebral ischemia monitored by intracerebral microdialysis. J Neurochem 43: 1369-1374
2. Choi DW (1988) Glutamate neurotoxicity and disease of the nervous system. Neuron 1: 623-634
3. Hillered L, Hallström Å, Segersvärd S, Persson L, Ungerstedt U (1990) Dynamics of extracellular metabolites in the striatum after middle cerebral artery occlusion in the rat monitored by intracerebral microdialysis. J Cereb Blood Flow Metab 10: 149-151
4. Lindroth P, Mopper K (1979) High performance liquid chromatographic determination of subpicomole amounts of amino acids by precolumn fluorescence derivatization with o-phthaldialdehyde. Anal Chem 51: 127-132
5. Shimada N, Graf R, Rosner G, Wakayama A, George CP, Heiss W-D (1989) Ischemic flow thresholds for extracellular glutamate increase in cerebral cortex. J Cereb Blood Flow Metab 9: 603-606
6. Siesjö BK, Bengtsson F (1989) Calcium fluxes, calcium antagonists and calcium related pathology in brain ischemia, hypoglycemia and spreading depression; a unifying hypothesis. J Cereb Blood Flow Metab 9: 127-140
7. Szatkowski M, Attwell D (1994) Triggering and execution of neuronal death in brain ischemia: two phases of glutamate release by different mechanisms. Trends Neurosci 17: 359-365
8. Säveland H, Hillman J, Brandt L, Edner G, Jakobsson K-E, Algers G (1992) Overall outcome in aneurysmal subarachnoid hemorrhage. A prospective study from neurosurgical units in Sweden during a 1-year period. J Neurosurg 76: 729-734
9. Säveland H, Nilsson OG, Boris-Möller F, Wieloch T, Brandt L (1995) Intracerebral microdialysis of glutamate and aspartate in two vascular territories after aneurysmal subarachnoid hemorrhage. Neurosurgery 38: 12-20
10. Ungerstedt U (1984) Measurement of neurotransmitter release by intracranial dialysis. In: Marsden CA (ed) Measurements of neurotransmitter release in vivo. Wiley, New York, pp 81-105