In vivo microdialysis to characterize drug transport in brain tumors: Analysis of methotrexate uptake in rat glioma-2 (RG-2)-bearing rats

Cancer Chemotherapy and Pharmacology

Volumn 38, Issue 6, 1996, Pages 499-507

  Devineni, Damayanthi ^a   Klein Szanto, Andres ^a   Gallo, James M ^a  

^a FOX CHASE CANCER CENTER   (United States)

Author keywords

Methotrexate; Microdialysis; Pharmacokinetics; RG 2 glioma

Indexed keywords

METHOTREXATE;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; AREA UNDER THE CURVE; ARTICLE; BLOOD BRAIN BARRIER; BRAIN; CACHEXIA; CONTROLLED STUDY; DRUG BLOOD LEVEL; DRUG CLEARANCE; DRUG DETERMINATION; DRUG DISTRIBUTION; DRUG TISSUE LEVEL; DRUG TRANSPORT; DRUG UPTAKE; GLIOMA; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; INFORMATION PROCESSING; INTERSTITIAL FLUID; INTRAARTERIAL DRUG ADMINISTRATION; MALE; MICRODIALYSIS; NONHUMAN; PRIORITY JOURNAL; RAT; STEADY STATE; TECHNIQUE; TOTAL BODY WATER;

ANIMALS; ANTIMETABOLITES, ANTINEOPLASTIC; AREA UNDER CURVE; BRAIN CHEMISTRY; BRAIN NEOPLASMS; GLIOMA; MALE; METHOTREXATE; MICRODIALYSIS; NEOPLASM TRANSPLANTATION; RATS; RATS, INBRED F344; TUMOR CELLS, CULTURED;

EID: 0029838343     PISSN: 03445704     EISSN: None     Source Type: Journal    
DOI: 10.1007/s002800050518     Document Type: Article

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