Genetic risk factor characterizes abdominal aortic aneurysm from arterial occlusive disease in human beings: CCR5 Δ32 deletion

Journal of Vascular Surgery

Volumn 40, Issue 5, 2004, Pages 995-1000

  Ghilardi, Giorgio ^a   Biondi, Maria Luisa ^b   Battaglioli, Lodovica ^b   Zambon, Antonella ^c   Guagnellini, Emma ^b   Scorza, Roberto ^a  

^a UNIVERSITY OF MILAN   (Italy)

^b Lab Chim Clin Microbiol Osp S

^c UNIVERSITY OF MILANO BICOCCA   (Italy)

Author keywords

[No Author keywords available]

Indexed keywords

ABDOMINAL AORTA ANEURYSM; ADULT; AGED; ALLELE; ARTICLE; CLINICAL FEATURE; CONTROLLED STUDY; DIAGNOSTIC TEST; FEMALE; GENE DELETION; GENE MUTATION; GENETIC POLYMORPHISM; GENETIC RISK; GENOTYPE; HUMAN; MAJOR CLINICAL STUDY; MALE; MULTIPLE REGRESSION; PERIPHERAL OCCLUSIVE ARTERY DISEASE; PRIORITY JOURNAL; RISK FACTOR;

AGED; ANEURYSM, RUPTURED; ANGIOGRAPHY; AORTIC ANEURYSM, ABDOMINAL; ARTERIAL OCCLUSIVE DISEASES; BASE SEQUENCE; CAROTID STENOSIS; CASE-CONTROL STUDIES; COHORT STUDIES; CONFIDENCE INTERVALS; FEMALE; GENETIC PREDISPOSITION TO DISEASE; HUMANS; MALE; MIDDLE AGED; MOLECULAR SEQUENCE DATA; ODDS RATIO; POLYMERASE CHAIN REACTION; POLYMORPHISM, GENETIC; PROBABILITY; PROGNOSIS; RECEPTORS, CCR5; RISK ASSESSMENT; SENSITIVITY AND SPECIFICITY; SEVERITY OF ILLNESS INDEX; SURVIVAL ANALYSIS;

EID: 8844286107     PISSN: 07415214     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.jvs.2004.08.014     Document Type: Article

References (33)

1. S.T.R. MacSweenwy, J.T. Powell, R.M. Greenhalg Pathogenesis of abdominal aortic aneurysm Br J Surg 81 1994 935 941
2. R.W. Thompson Basic science of abdominal aortic aneurysms: emerging therapeutic strategies for an unresolved clinical problem Curr Opin Cardiol 11 1996 504 518
3. T. Freestone, R.J. Turner, A. Coady, D.J. Higman, P.M. Greenhalg, J.T. Powell Inflammation and matrix metalloproteinases in enlarging abdominal aortic aneurysm Arteioscler Thromb 15 1995 1145 1151
4. A.E. Koch, G.K. Haines, R.J. Rizzo, J.A. Radosevich, R.M. Pope, P.G. Robinson Human abdominal aortic aneurysms: immunophenotypic analysis suggesting an immune-mediated response Am J Pathol 137 1990 1199 1213
5. D.V. Parums, D.C. Dunn, A.K. Dixon, M.J. Mitchinson Characterization of inflammatory cells in patients with chronic periaortites Am J Cardiovasc Pathol 3 1990 121 129
6. M. Baggiolini Chemokines and leukocyte traffic Nature 392 1998 565 568
7. A.D. Luster Chemokines: chemotactic cytokines that mediated inflammation N Engl J Med 338 1998 436 445
8. M.W. Smith, M. Dean, M. Carrington, C. Winkler, G.A. Huttley, D.A. Lomb Contrasting influence of CCR2 and CCR5 variants of HIV infection and disease progression Science 277 1997 959 965
9. C. Winkler, W. Modi, M.W. Smith, G.W. Nelson, X. Wu, M. Carrington ALIVE Study, Hemophilia Growth and Development Study (HGDS), Multicenter AIDS Cohort Study (MACS), Multicenter Hemophilia Cohort Study (MHCS), San Francisco City Cohort (SFCC) Genetic restriction of AIDS pathogenesis by an SDF-1 chemokine gene variant Science 279 1998 389 393
10. Barcellos LF, Schito AM, Rimmler JB, Vittinghoff E, Shihh A, Lincoln R, et al, for the Multiple Sclerosis Genetic Group: CC-chemokine receptor 5 polymorphism and age of onset in familial multiple sclerosis Immunogenetics 48 1998 1462 1465
11. J.B. Rottman, K.P. Ganley, K. Williams, L. Wu, C.R. Mackay, D.J. Ringler Cellular localization of the chemokine receptor CCR5 Am J Pathol 151 1997 1341 1351
12. M. Mack, J. Cihak, D. Siminis, B. Luckow, A.E.I. Proudfoot, J. Planchy Expression and characterization of the chemokine receptors CCR2 and CCR5 in mice J Immunol 166 2001 4697 4704
13. O. Berger, X. Gan, C. Gujuluva, A.R. Burns, M. Sulur, D. Way CXC and CC chemokine receptors on coronary and brain endothelia Mol Med 5 1999 795 805
14. A.D. Schecter, T.M. Calderon, A.B. Berman, C.M. McManus, J.T. Fallon, M. Rossikhina Human vascular smooth muscle cells possess functional CCR5 J Biol Chem 275 2000 5466 5471
15. Wilcox JN, Nelken NA, Coughlin SR, Gordon D, Shall TJ. Local expression of inflammatory cytokines in human atherosclerotic plaques. J Atheroscler Thromb 1994;1:S10-3.
16. P. Gonzalez, R. Alvarez, A. Batalla, J.R. Reguero, V. Alvarez, A. Astudillo Genetic variation at the chemokine receptors CCR5/CCR2 in myocardial infraction Gene Immun 2 2001 191 195
17. C. Szalai, J. Duba, Z. Prohaszka, A. Kalina, T. Szabo, B. Nagy Involvement of polymorphisms in the chemokines system in the susceptibility for coronary artery disease (CAD) Atherosclerosis 158 2001 233 239
18. J. Biller, W.M. Feinberg, J.E. Castaldo, A.D. Whittemore, R.E. Harbaugh, R.J. Dempsey Guidelines for carotid endarterectomy: a statement for healthcare professionals from a special writing group of the Stroke Council, American Heart Association Circulation 97 1998 501 509
19. J.F. Blanchard, H.K. Armenian, P.P. Friesen Risk factors for abdominal aortic aneurysm: results of a case-control study Am J Epidemiol 151 2000 575 583
20. A.V. Chobanian, G.L. Bakris, H.R. Black, W.C. Cushman, L.A. Green, J.L. Izzo National High Blood Pressure Education Program Coordinating Committee Seventh report of the Joint National Committee on Prevention, Detection, Evaluation and Treatment of High Blood Pressure Hypertension 42 2003 1206 1252
21. R. Ross The pathogenesis of atherosclerosis: a prospective for the 1990s Nature 362 1993 801 809
22. R. Ross Atherosclerosis: an inflammatory disease N Engl J Med 340 1999 115 126
23. T.J. Reape, P.H. Groot Chemokines and atherosclerosis Atherosclerosis 147 1999 213 235
24. C.K. Glass, J.L. Witztum Atherosclerosis: the road ahead Cell 104 2001 503 516
25. A. Kadar, T. Glasz Development of atherosclerosis and plaque biology Cardiovasc Surg 9 2001 109 121
26. G. Ailawadi, J.L. Eliason, G.R. Upchurch JR Current concepts in the pathogenesis of abdominal aortic aneurysm J Vasc Surg 38 2003 584 588
27. A.D. Schecter, T.M. Calderon, A.B. Berman, C.M. McManus, J.T. Fallon, M. Rossikhina Human vascular smooth muscle cells possess functional CCR5 J Biol Chem 275 2000 5466 5471
28. D. Reed, C. Reed, G. Stemmeermann, T. Hayashi Are aortic aneuysms caused by atherosclerosis? Circulation 85 1992 205 211
29. P.J. Armstong, J.M. Johanning, W.C. Calton JR, J.R. Delatore, D.P. Franklin, D.C. Han Differential gene expression in human abdominal aorta: aneurysmal versus occlusive disease J Vasc Surg 35 2002 346 355
30. W.A. Kuziel, T.C. Dawson, M. Quinones, E. Garavito, G. Chenaux, S.S. Ahuja CCR5 deficency is not protective in the early stages of atherogenesis in apoE knockout mice Atherosclerosis 167 2003 25 32
31. J. Frostegåard, A.K. Ulfrgren, P. Nyberg, U. Hedin, J. Swedenborg, U. Andersson Cytokine expression in advanced human atherosclerotic plaques: dominance of pro-inflammatory (Th1) and macrophage-stimulating cytokines Atherosclerosis 145; 1999 33 43
32. U. Schönbeck, G.K. Sukhova, N. Gerdes, P. Libby Th2 predominant immune responses prevail in human abdominal aortic aneurysm Am J Pathol 161 2002 499 506
33. S. Xia, K. Ozvath, H. Hirose, M.D. Tilson Partial amino acid sequence of a novel 40-kDa human aortic protein, with birtonectin-like, fibrinogen-like, and calcium binding domains: aortic aneurysm-associated protein-40 (AAAP-40) Biochem Biophys Res Comm 219 1996 36 39