Intrathecal clonidine inhibits mechanical allodynia via activation of the spinal muscarinic M 1 receptor in streptozotocin-induced diabetic mice

European Journal of Pharmacology

Volumn 505, Issue 1-3, 2004, Pages 75-82

  Koga, Kohei ^a   Honda, Kenji ^a   Ando, Suguru ^a   Harasawa, Ichiro ^b   Kamiya, Hiro O ^a   Takano, Yukio ^a  

^a FUKUOKA UNIVERSITY   (Japan)

^b UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

2 Adrenoreceptor; Allodynia; Diabetes; Muscarinic receptor; Spinal cord

Indexed keywords

4 DIPHENYLACETOXY 1 METHYLPIPERIDINE; [4 [(3 CHLOROPHENYL)CARBAMOYLOXY] 2 BUTYNYL]TRIMETHYLAMMONIUM; ATROPINE; CLONIDINE; METHOCTRAMINE; MUSCARINIC M1 RECEPTOR; PIRENZEPINE; STREPTOZOCIN; YOHIMBINE;

ALLODYNIA; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CONTROLLED STUDY; CORRELATION ANALYSIS; DIABETES MELLITUS; DRUG ANTAGONISM; DRUG EFFECT; DRUG SELECTIVITY; MALE; MECHANICAL STIMULATION; MOUSE; NONHUMAN; PRIORITY JOURNAL; SENSITIVITY ANALYSIS;

(4-(M-CHLOROPHENYLCARBAMOYLOXY)-2-BUTYNYL)TRIMETHYLAMMONIUM CHLORIDE; ANALGESICS; ANIMALS; ATROPINE; BLOOD GLUCOSE; CLONIDINE; DIABETES MELLITUS, EXPERIMENTAL; DIAMINES; INJECTIONS, SPINAL; MALE; MICE; MOTOR ACTIVITY; MUSCARINIC AGONISTS; MUSCARINIC ANTAGONISTS; PAIN; PAIN THRESHOLD; PIPERIDINES; PIRENZEPINE; RECEPTOR, MUSCARINIC M1; RECEPTOR, MUSCARINIC M2; RECEPTOR, MUSCARINIC M3; SPINAL CORD; STREPTOZOCIN; STRESS, MECHANICAL; TIME FACTORS;

EID: 8844224082     PISSN: 00142999     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.ejphar.2004.10.033     Document Type: Article

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