Muscarinic facilitation of GABA release in substantia gelatinosa of the rat spinal dorsal horn

Journal of Physiology

Volumn 508, Issue 1, 1998, Pages 83-93

  Baba, H ^a,d   Kohno, T ^a   Okamoto, M ^a   Goldstein, P A ^b   Shimoji, K ^a   Yoshimura, M ^c  

^a NIIGATA UNIVERSITY   (Japan)

^b Columbia University ^*  (United States)

^c SAGA UNIVERSITY   (Japan)

^d MASSACHUSETTS GENERAL HOSPITAL   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

4 AMINOBUTYRIC ACID RECEPTOR; ACETYLCHOLINE; ANTINOCICEPTIVE AGENT; ARECAIDINE; ATROPINE; CARBACHOL; CHOLINESTERASE INHIBITOR; HEXAHYDROSILADIFENIDOL; METHOCTRAMINE; MUSCARINIC AGENT; MUSCARINIC M1 RECEPTOR; MUSCARINIC M2 RECEPTOR; MUSCARINIC RECEPTOR; NEOSTIGMINE; PIRENZEPINE; POSTSYNAPTIC RECEPTOR; TETRODOTOXIN; [4 [(3 CHLOROPHENYL)CARBAMOYLOXY] 2 BUTYNYL]TRIMETHYLAMMONIUM; 4 AMINOBUTYRIC ACID; 4 AMINOBUTYRIC ACID A RECEPTOR; 6 CYANO 7 NITRO 2,3 QUINOXALINEDIONE; MUSCARINIC M3 RECEPTOR;

4 AMINOBUTYRIC ACID RELEASE; ACETYLCHOLINE RELEASE; ANIMAL CELL; ANTINOCICEPTION; ARTICLE; CHOLINERGIC SYSTEM; CONTROLLED STUDY; DRUG EFFECT; GABAERGIC TRANSMISSION; INTERNEURON; ION CURRENT; NERVE CELL EXCITABILITY; NERVE ENDING; NONHUMAN; PATCH CLAMP; PRESYNAPTIC NERVE; PRIORITY JOURNAL; RAT; SPINAL CORD DORSAL HORN; SUBSTANTIA GELATINOSA; DECAY TIME CONSTANT; GABAERGIC SYSTEM; INHIBITORY POSTSYNAPTIC POTENTIAL; PATCH CLAMP TECHNIQUE; PRESYNAPTIC INHIBITION; STEADY STATE; VENTRAL ROOT;

EID: 0032055904     PISSN: 00223751     EISSN: None     Source Type: Journal    
DOI: 10.1111/j.1469-7793.1998.083br.x     Document Type: Article

References (37)

1. ABRAM, S. E. & O'CONNOR, T. C. (1995). Characteristics of the analgesic effects and drug interactions of intrathecal carbachol in rats. Anesthesiology 83, 844-849.
2. BENARDO, L. S. & PRINCE, D. A. (1982). Cholinergic excitation of mammalian hippocampal pyramidal cells. Brain Research 249 315-331.
3. BORGES, L. F. & IVERSEN, S. D. (1986). Topography of choline acetyltransferase immunoreactive neurons and fibers in the rat spinal cord. Brain Research 362, 140-148.
4. BOUAZIZ, H., TONG, C. & EISENACH, J. C. (1995). Postoperative analgesia from intrathecal neostigmine in sheep. Anesthesia & Analgesia 80, 1140-1144.
5. BROWN, A. G. (1981). Organization in the Spinal Cord. Springer-Verlag, Berlin.
6. BUCKLEY, N. J., BONNER, T. I., BUCKLEY, C. M. & BRANN, M. R. (1989). Antagonist binding properties of five cloned muscarinic receptors expressed in CHO-K1 cells. Molecular Pharmacology 35, 469-476.
7. DORJE, F., WESS, J., LAMBRECHT, G., TACKE, R., MUTSCHLER, E. & BRANN, M. R. (1991). Antagonist binding profiles of five cloned human muscarinic receptor subtypes. Journal of Pharmacology & Experimental Therapeutics 256, 727-733.
8. GILLBERG, P. G. & ASKMARK, H. (1991). Changes in cholinergic and opioid receptors in the rat spinal cord, dorsal root and sciatic nerve after ventral and dorsal root lesion. Journal of Neural Transmission 85, 31-39.
9. GILLBERG, P. G., HARTVIG, P., GORDH, T., SOTTILE, A., JANSSON, I., ARCHER, T. & POST, C. (1990). Behavioral effects after intrathecal administration of cholinergic receptor agonists in the rat. 4 Psychopharmacology 100, 464-469.
10. GILLBERG, P. G. & WIKSTEN, B. (1986). Effects of spinal cord lesions and rhizotomies on cholinergic and opiate receptor binding sites in rat spinal cord. Acta Physiologica Scandinavica 126, 575-582.
11. GRUDT, T. J. & WILLIAMS, J. T. (1994). μ-Opioid agonists inhibit spinal trigeminal substantia gelatinosa neurons in guinea pig and rat. Journal of Neuroscience 14, 1646-1654.
12. HOOD, D. D., MALLAK, K. A., EISENACH, J. C. & TONG, C. (1996). Interaction between intrathecal neostigmine and epidural clonidine in human volunteers. Anesthesiology 85, 315-325.
13. 3H]choline into the rat spinal cord. Neuroscience 18, 901-916.
14. KUMAZAWA, T. & PERL, E. R. (1978). Excitation of marginal and substantia gelatinosa neurons in the primate spinal cord: indications of their place in dorsal horn functional organization. Journal of Comparative Neurology 177, 417-434.
15. LACEY, M. G., CALABRESI, P. & NORTH, R. A. (1990). Muscarine depolarizes rat substantia nigra zona compacta and ventral tegmental neurons in vitro through M1-like receptors. Journal of Pharmacology and Experimental Therapeutics 253, 395-400.
16. LAING, I., TODD, A. J., HEIZMANN, C. W. & SCHMIDT, H. H. (1994). Subpopulations of GABAergic neurons in laminae I-III of rat spinal dorsal horn defined by coexistence with classical transmitters, peptides, nitric oxide synthase or parvalbumin. Neuroscience 61, 123-132.
17. LIAO, D., HESSLER, N. A. & MALINOW, R. (1995). Activation of postsynaptically silent synapses during pairing-induced LTP in CA1 region of hippocampal slice. Nature 375, 400-404.
18. MCCORMICK, D. A. & PRINCE, D. A. (1986). Mechanisms of action of acetylcholine in the guinea-pig cerebral cortex in vitro. Journal of Physiology 375, 169-194.
19. MADISON, D. V., LANCASTER, B. & NICOLL, R. A. (1987). Voltage clamp analysis of cholinergic action in the hippocampus. Journal of Neuroscience 7, 733-741.
20. MALGAROLI, A. & TSIEN, R. W. (1992). Glutamate-induced long-term potentiation of the frequency of miniature synaptic currents in cultured hippocampal neurons. Nature 357, 134-139.
21. NAGUIB, M. & YAKSH, T. L. (1994). Antinociceptive effects of spinal cholinesterase inhibition and isobolographic analysis of the interaction with μ and α2 receptor systems. Anesthesiology 80, 1338-1348.
22. PITLER, T. A. & ALGER, B. E. (1992). Cholinergic excitation of GABAergic interneurons in the rat hippocampal slice. Journal of Physiology 450, 127-142.
23. RIBEIRO-DA-SILVA, A. & CUELLO, A. C. (1990). Choline acetyl-transferase-immunoreactive profiles are presynaptic to primary sensory fibers in the rat superficial dorsal horn. Journal of Comparative Neurology 295, 370-384.
24. SCATTON, B., DUBOIS, A., JAVUY-AGID, F. & CAMUS, A. (1984). Autoradiographic localization of muscarinic cholinergic receptors at various segmental levels of the human spinal cord. Neuroscience Letters 49, 239-245.
25. SMITH, M. D., YANG, X. H., NHA, J. Y. & BUCCAFUSCO, J. J. (1989). Antinociceptive effect of spinal cholinergic stimulation: interaction with substance P. Life Sciences 45, 1255-1261.
26. SPIKE, R. C., TODD, A. J. & JOHNSTON, H. M. (1993). Coexistence of NADPH diaphorase with GABA, glycine and acetylcholine in rat spinal cord. Journal of Comparative Neurology 335, 320-333.
27. TODD, A. J. & SULLIVAN, A. C. (1990). Light microscope study of the coexistence of GABA-like and glycine-like immunoreactivities in the spinal cord of the rat. Journal of Comparative Neurology 296, 496-505.
28. TRAVAGLI, R. A. (1996). Muscarinic receptor activation in the substantia gelatinosa of the spinal trigeminal nucleus of the guinea pig. Journal of Neurophysiology 76, 3817-3822.
29. UCHIMURA, N. & NORTH, R. A. (1990). Muscarine reduces inwardly rectifying potassium conductance in rat nucleus accumbens neurones. Journal of Physiology 422, 369-380.
30. 3H]quinuclidinylbenzilate binding sites. Brain Research 345, 196-199.
31. YAJIRI, Y., YOSHIMURA, M., OKAMOTO, M., TAKAHASHI, H. & HIGASHI, H. (1997). A novel slow excitatory postsynaptic current in substantia gelatinosa neurons of the rat spinal cord in vitro. Neuroscience 76, 673-688.
32. 3H]pirenzepine. European Journal of Pharmacology 91, 147-149.
33. YOSHIMURA, M. & JESSELL, T. M. (1989). Primary afferent-evoked synaptic responses and slow potential generation in rat substantia gelatinosa neurons in vitro. Journal of Neurophysiology 62, 96-108.
34. YOSHIMURA, M. & NISHI, S. (1993). Blind patch-clamp recordings from substantia gelatinosa neurons in adult rat spinal cord slices: pharmacological properties of synaptic currents. Neuroscience 53, 519-526.
35. YOSHIMURA, M. & NISHI, S. (1995). Primary afferent-evoked glycine-and GABA-mediated IPSPs in substantia gelatinosa neurones in the rat spinal cord in vitro. Journal of Physiology 482, 29-38.
36. ZHUO, M. & GEBHART, G. F. (1990). Spinal cholinergic and monoaminergic receptors mediate descending inhibition from the nuclei reticularis gigantocellularis and gigantocellularis pars alpha in the rat. Brain Research 535, 67-78.
37. ZHUO, M. & GEBHART, G. F. (1991). Tonic cholinergic inhibition of spinal mechanical transmission. Pain 46, 211-222.