Serine 171, A Conserved Residue in the γ-Aminobutyric Acid Type A (GABAA) Receptor γ2 Subunit, Mediates Subunit Interaction and Cell Surface Localization

Journal of Biological Chemistry

Volumn 279, Issue 14, 2004, Pages 14179-14183

  Jin, Pei ^a   Walther, Dirk ^a   Zhang, Juan ^a   Rowe Teeter, Courtney ^a   Fu, Glenn K ^a  

^a Experimental Station   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BIOLOGICAL ORGANS; CELLS; NEUROLOGY; ORGANIC ACIDS;

CELL SURFACE LOCALIZATION; NEUROSCIENCE;

BIOCHEMISTRY;

4 AMINOBUTYRIC ACID A RECEPTOR; ION CHANNEL; PROTEIN SUBUNIT; SERINE;

AMINO ACID SUBSTITUTION; ARTICLE; CELL SURFACE; HUMAN; HUMAN CELL; MUTATION; PRIORITY JOURNAL; PROTEIN ASSEMBLY; PROTEIN LOCALIZATION; PROTEIN PROTEIN INTERACTION; PROTEIN STABILITY; STRUCTURE ANALYSIS;

EID: 1842790786     PISSN: 00219258     EISSN: None     Source Type: Journal    
DOI: 10.1074/jbc.M313411200     Document Type: Article

References (24)

1. Ernst, M., Brauchart, D., Boresch, S., and Sieghart, W. (2003) Neuroscience 119, 933-943
2. Ortells, M. O., and Lunt, G. G. (1995) Trends Neurosci. 18, 121-127
3. Davies, P. A., Hanna, M. C., Hales, T. G., and Kirkness, E. F. (1997) Nature 385, 820-823
4. McKernan, R. M., and Whiting, P. J. (1996) Trends Neurosci. 19, 139-143
5. Bloom, F. E. (2001) in Goodman & Gilman's Pharmacological Basis of Therapeutics (Hardman, J. G., and Limbird, L. L., eds) 10th Ed., McGraw-Hill Book Co., New York
6. Hedblom, E., and Kirkness, E. F. (1997) J. Biol. Chem. 272, 15346-15350
7. Whiting, P. J., McAllister, G., Vassilatis, D., Bonnert, T. P., Heavens, R. P., Smith, D. W., Hewson, L., O'Donnell, R., Rigby, M. R., Sirinathsinghji, D. J., Marshall, G., Thompsen, S. A., Wafford, K. A., and Vasilatis, D. (1997) J. Neurosci. 17, 5027-5037
8. Cutting, G. R., Lu, L., O'Hara, B. F., Kasch, L. M., Montrese-Rafizadeh, C., Donovan, D. M., Shimada, S., Antonarakis, S. E., Guggino, W. B., Uhl, G. R., and Kazazian, H. H. (1991) Proc. Natl. Acad. Sci. U. S. A. 88, 2673-2677
9. Nayeem, N., Green, T. P., Martin, I. L., and Barnard, E. A. (1994) J. Neurochem. 62, 815-818
10. Pregenzer, J. F., Im, W. B., Carter, D. B., and Thomsen, D. R. (1993) Mol. Pharmacol. 43, 801-806
11. Connolly, C. N., Krishek, B. J., McDonald, B. J., Smart, T. G., and Moss, S. J. (1996) J. Biol. Chem. 271, 89-96
12. Klausberger, T., Fuchs, K., Mayer, B., Ehya, N., and Sieghart, W. (2000) J. Biol. Chem. 275, 8921-8928
13. Klausberger, T., Ehya, N., Fuchs, K., Fuchs, T., Ebert, V., Sarto, I., and Sieghart, W. (2001) J. Biol. Chem. 276, 16024-16032
14. Klausberger, T., Sarto, I., Ehya, N., Fuchs, K., Furtmuller, R., Mayer, B., Huck, S., and Sieghart, W. (2001) J. Neurosci. 21, 9124-9133
15. Bollan, K., King, D., Robertson, L. A., Brown, K., Taylor, P. M., Moss, S. J., and Connolly, C. N. (2003) J. Biol. Chem. 278, 4747-4755
16. Jin, P., Zhang, J., Rowe-Teeter, C., Yang, J., Stuve, L. L., and Fu, G. K. (2004) J. Biol. Chem. 279, 1408-1414
17. Jin, P., Fu, G. K., Wilson, A. D., Yang, J., Chien, D., Hawkins, P. R., Au-Young, J., and Stuve, L. L. (2004) Genetics, in press
18. Brejc, K., van Dijk, W. J., Klaassen, R. V., Schuurmans, M., van Der Oost, J., Smit, A. B., and Sixma, T. K. (2001) Nature 411, 269-276
19. Taylor, P. M., Connolly, C. N., Kittler, J. T., Gorrie, G. H., Hosie, A., Smart, T. G., and Moss, S. J. (2000) J. Neurosci. 20, 1297-1306
20. Taylor, P. M., Thomas, P., Gorrie, G. H., Connolly, C. N., Smart, T. G., and Moss, S. J. (1999) J. Neurosci. 19, 6360-6371
21. Russell, R. B., Saqi, M. A., Sayle, R. A., Bates, P. A., and Sternberg, M. J. (1997) J. Mol. Biol. 269, 423-439
22. Cromer, B. A., Morton, C. J., and Parker, M. W. (2002) Trends Biochem. Sci. 27, 280-287
23. Trudell, J. (2002) Biochim. Biophys. Acta 1565, 91-96
24. Guex, N., and Peitsch, M. C. (1997) Electrophoresis 18, 2714-2723