JTE-522, a selective COX-2 inhibitor, interferes with the growth of lung metastases from colorectal cancer in rats due to inhibition of neovascularization: A vascular cast model study

International Journal of Cancer

Volumn 112, Issue 6, 2004, Pages 920-926

  Kobayashi, Hirotoshi ^a   Gonda, Tsuyoshi ^a   Uetake, Hiroyuki ^a   Higuchi, Tetsuro ^a   Enomoto, Masayuki ^a   Sugihara, Kenichi ^a  

^a TOKYO MEDICAL AND DENTAL UNIVERSITY   (Japan)

Author keywords

Angiogenesis; Colorectal cancer; COX 2; Metastasis; Vascular cast

Indexed keywords

CYCLOOXYGENASE 2 INHIBITOR; TILMACOXIB;

ANGIOGENESIS; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; COLORECTAL CANCER; CONTROLLED STUDY; DRUG EFFECT; GROWTH INHIBITION; LUNG BLOOD VESSEL; LUNG METASTASIS; LUNG PARENCHYMA; MALE; MICROVASCULATURE; NEOVASCULARIZATION (PATHOLOGY); NONHUMAN; PRIORITY JOURNAL; RAT; SCANNING ELECTRON MICROSCOPY; SOLID TUMOR; TUMOR BLOOD FLOW; TUMOR GROWTH; TUMOR VASCULARIZATION; TUMOR VOLUME;

ANGIOGENESIS INHIBITORS; ANIMALS; ANTINEOPLASTIC AGENTS; BENZENESULFONATES; CELL LINE, TUMOR; COLORECTAL NEOPLASMS; CYCLOOXYGENASE 2; ENZYME INHIBITORS; ISOENZYMES; LOGISTIC MODELS; LUNG NEOPLASMS; MALE; MICROCIRCULATION; MICROSCOPY, ELECTRON, SCANNING; NEOVASCULARIZATION, PATHOLOGIC; OXAZOLES; PROSTAGLANDIN-ENDOPEROXIDE SYNTHASES; PULMONARY CIRCULATION; RATS; RATS, INBRED F344;

EID: 8644280623     PISSN: 00207136     EISSN: None     Source Type: Journal    
DOI: 10.1002/ijc.20523     Document Type: Article

References (46)

1. Gutman M, Fidler IJ. Biology of human colon cancer metastasis. World J Surg 1995;19:226-34.
2. Folkman J. How is blood vessel growth regulated in normal and neoplastic tissue? Cancer Res 1986;46:467-73.
3. Folkman J. Endothelial cells and angiogenic growth factors in cancer growth and metastasis: introduction. Cancer Metastasis Rev 1990;9:171-4.
4. Liotta LA, Kleineman J, Saidel GM. Quantitative relationships of intravascular tumor cells, tumor vessels, and pulmonary metastases following tumor implantation. Cancer Res 1974;34:997-1004.
5. Blood CH, Zetter BR. Tumor interactions with the vasculature: angiogenesis and tumor metastasis. Biochim Biophys Acta 1990;1032:89-118.
6. Nagy JA, Brown LF, Senger DR. Pathogenesis of tumor stroma generation: a critical role for leaky blood vessels and fibrin deposition. Biochim Biophys Acta 1989;948:305-26.
7. Abrams HL, Spiro R. Metastases in carcinoma: analysis of 100 autopsied cases. Cancer 1950;3:74.
8. Weiss L, Grundmann E, Torhorst J, Hartveit F, Moberg I, Eder M, Fenoglio-Preiser C, Napier J, Horne C, Lopez M, Shaw-Dunn R, Sugar J, et al. Haematogenous metastatic patterns in colonic carcinoma: an analysis of 1541 necropsies. J Pathol 1986;150:195-203.
9. Gervaz P, Scholl B, Mainguene C, Poitry S, Gillet M, Wexner S. Angiogenesis of liver metastases. Dis Colon Rectum 2000;43:980-6.
10. Strohmeyer T, Haugeberg G, Lierse W. Angioarchitecture and blood supply of micro- and macrometastases in human livers. J Hepatol 1987;4:181-9.
11. Gonda T, Ishida H, Yoshinaga K, Sugihara K. Microvasculature of small liver metastases in rats. J Surg Res 2000;94:43-8.
12. Waddell WR, Loughry RW. Sulindac for polyposis of the colon. J Surg Oncol 1983;4:83-7.
13. Jones DA, Carlton DP, McIntyre TM, Zimmerman GA, Prescott SM. Molecular cloning of human prostaglandin endoperoxide synthase type II and demonstration of expression in response to cytokines. J Biol Chem 1993;268:9049-54.
14. Williams CS, DuBois RN. Prostaglandin endoperoxide synthase: why two isoforms? Am J Physiol 1996;270:G393-400.
15. Eberhart CE, Coffey RJ, Radhika A, Giardiello FM, Ferrenbach S, DuBois RN. Upregulation of cyclooxygenase-2 gene expression in human colorectal adenomas and adenocarcinomas. Gastroenterology 1994;107:1183-8.
16. Tsujii M, Kawano S, Tsuji S, Sawaoka H, Hori M, DuBois NR. Cyclooxygenase regulates angiogenesis induced by colon cancer cells. Cell 1998;93:705-16.
17. Swamy MV, Herzog CR, Rao CV. Inhibition of COX-2 in colon cancer cell lines by celecoxib increases the nuclear localization of active p53. Cancer Res 2003;63:5239-42.
18. Tsujii M, Kawano S, DuBois RN. Cyclooxygenase-2 expression in human colon cancer cells increases metastatic potential. Proc Natl Acad Sci USA 1997;94:3336-40.
19. Tomozawa S, Nagawa H, Tsuno N, Hatano K, Osada T, Kitayama J, Sunami E, Nita ME, Ishihara S, Yano H, Tsuruo T, Shibata Y, et al. Inhibition of haematogenous metastasis of colon cancer in mice by a selective COX-2 inhibitor, JTE-522. Br J Cancer 1999;81:1274-9.
20. Inoue Y, Kashima Y, Akizawa K, Hatakeyama K. A new rat colon cancer cell line metastasizes spontaneously: biologic characteristics and chemotherapeutic response. Jpn J Cancer Res 1991;82:90-7.
21. Matsushita M, Masaki M, Yagi Y, Tanaka T, Wakitani K. Pharmacological profile of JTE-522, a novel prostaglandin H synthase-2 inhibitor, in rats. Inflamm Res 1997;46:461-6.
22. Murakami T. Application of the scanning electron microscope to the study of fine distribution of blood vessels. Arch Histol Jpn 1971;32:445-54.
23. Schraufnagel DE. The lung microstructure. In: Scanning electron microscopy of vascular casts: method and applications. (Motta PM, Murakami T, Fujita H, eds.). Norwell, MA: Kluwer Academic Publishers, 1992, 123-37.
24. Newton TH, Preger L. Selective bronchial arteriography. Radiology 1965;84:1043-51.
25. Noonan CD, Margulis AR, Wright R. Bronchial arterial patterns in pulmonary metastases. Radiology 1965;84:1033-42.
26. Viamonte M Jr, Parks RE, Smoak WM III. Guided catheterization of bronchial arteries: I. technical consideration. Radiology 1965;85:205-30.
27. Viamonte M Jr. Selective bronchial arteriography in man: preliminary report. Radiology 1964;83:830-9.
28. Viamonte M Jr. Angiographic evaluation of lung neoplasms. Radiol Clin North Am 1965;3:529-42.
29. Milne EN, Zerhouni AE. Blood supply of pulmonary metastases. J Thorac Imag 1987;2:15-23.
30. Osaki T, Oyama T, Takenoyama M. Taga S, So T, Yamashita T, Nakata S, Nakanishi R, Yasumoto K. Feasibility of induction chemotherapy using bronchial arterial infusion for locally advanced non-small cell lung cancer: a pilot study. Surg Today 2002;32:772-8.
31. Reddy BS, Rao CV, Seibert K. Evaluation of cyclooxygenase-2 inhibitor for potential chemopreventive properties in colon carcinogenesis. Cancer Res 1996;56:4566-9.
32. Oshima M, Dinchuk JE, Kargman S, Oshima H, Hancock B, Kwong E, Trzaskos JM, Evans JF, Taketo MM. Suppression of intestinal polyposis in apcΔ716 knockout mice by inhibition of cyclooxygenase 2 (COX-2). Cell 1996;87:803-9.
33. Fujita T, Matsui M, Takaku K, Uetake H, Ichikawa W, Taketo MM, Sugihara K. Size- and invasion-dependent increase in cyclooxygenase 2 levels in human colorectal carcinomas. Cancer Res 1998;58:4823-6.
34. Hasegawa K, Ichikawa W, Fujita T, Ohno R, Okusa T, Yoshinaga K, Sugihara K. Expression of cyclooxygenase-2 (COX-2) mRNA in human colorectal adenomas. Eur J Cancer 2001;37:1469-74.
35. Sato T, Yoshinaga K, Okabe S, Okawa T, Enomoto M, Takizawa T, Sugihara K. Cyclooxygenase-2 expression in colorectal adenomas. Dis Colon Rectum 2003;46:786-92.
36. Kawamori K, Rao CV, Seibert K, Reddy BSC. Chemopreventive activity of celecoxib, a specific cyclooxygenase-2 inhibitor, against colon carcinogenesis. Cancer Res 1998;58:409-12.
37. Jacoby RF, Seibert K, Cole CE, Kelloff G, Lubet RA. The cyclooxygenase-2 inhibitor celecoxib is a potent preventive and therapeutic agent in the Min mouse model of adenomatous polyposis. Cancer Res 2000;60:5040-4.
38. Oshima M, Murai N, Kargman S, Arguello M, Luk P, Kwong E, Taketo MM, Evans JF. Chemoprevention of intestinal polyposis in ApcA716 mouse by rofecoxib, a specific cyclooxygenase-2 inhibitor. Cancer Res 2001;61:1733-40.
39. Masferrer JL, Leahy KM, Koki AT, Zweifel BS, Settle SL, Woerner BM, Edwards DA, Flickinger AG, Moore RJ, Seibert K. Antiangiogenic and antitumor activities of cyclooxygenase-2 inhibitors. Cancer Res 2000;60:1306-11.
40. Williams CS, Mann M, DuBois RN. The role of cyclooxygenases in inflammation, cancer, and development. Oncogene 1999;18:7908-16.
41. Yoshida S, Amano H, Hayashi I, Kitasato H, Kamata M, Inukai M, Yoshimura H, Majima M. COX-2/VEGF-dependent facilitation of tumor-associated angiogenesis and tumor growth in vivo. Lab Invest 2003;83:1385-94.
42. Liang JT, Huang KC, Jeng YM, Lee PH, Lai HS, Hsu HC. Microvessel density, cyclo-oxygenase 2 expression, K-ras mutation and p53 overexpression in colonic cancer. Br J Surg 2004;91:355-61.
43. Sun Y, Tang XM, Half E, Kuo MT, Sinicrope FA. Cyclooxygenase-2 overexpression reduces apoptotic susceptibility by inhibiting the cytochrome c-dependent apoptotic pathway in human colon cancer cells. Cancer Res 2002;62:6323-8.
44. Nagatsuka I, Yamada N, Shimizu S, Ohira M, Nishino H, Seki S, Hirakawa K. Inhibitory effect of a selective cyclooxygenase-2 inhibitor on liver metastasis of colon cancer. Int J Cancer 2002;100:515-9.
45. Wei M, Morimura K, Wanibuchi H, Shen J, Doi K, Mitsuhashi M, Moku M, Salim EI, Fukushima S. Chemopreventive effect of JTE-522, a selective cyclooxygenase-2 inhibitor, on 1,2-dimethylhydrazine-induced rat colon carcinogenesis. Cancer Lett 2003;202:11-6.
46. Kakiuchi Y, Tsuji S, Tsujii M, Murata H, Kawai N, Yasumaru M, Kimura A, Komori M, Irie T, Miyoshi E, Sasaki Y, Hayashi N, et al. Cyclooxygenase-2 activity altered the cell-surface carbohydrate antigens on colon cancer cells and enhanced liver metastasis. Cancer Res 20021;62:1567-72.