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Volumn 101, Issue 11, 1998, Pages 2468-2477

Sustained pulmonary hypertension and right ventricular hypertrophy after chronic hypoxia in mice with congenital deficiency of nitric oxide synthase

Author keywords

Circulation, pulmonary; Echocardiography, transesophageal; Gene deletion; Hypertension, pulmonary; Nitric oxide synthase

Indexed keywords

ENDOTHELIAL NITRIC OXIDE SYNTHASE; NITRIC OXIDE; UNCLASSIFIED DRUG;

EID: 0032102283     PISSN: 00219738     EISSN: None     Source Type: Journal    
DOI: 10.1172/JCI2356     Document Type: Article
Times cited : (199)

References (33)
  • 1
    • 0029055964 scopus 로고
    • Reduced expression of endothelial nitric oxide synthase in the lungs of patients with pulmonary hypertension
    • Giaid, A., and D. Saleh. 1995. Reduced expression of endothelial nitric oxide synthase in the lungs of patients with pulmonary hypertension. N. Engl. J. Med. 333:214-221.
    • (1995) N. Engl. J. Med. , vol.333 , pp. 214-221
    • Giaid, A.1    Saleh, D.2
  • 2
    • 0030955626 scopus 로고    scopus 로고
    • Pulmonary vasoconstriction and hypertension in mice with targeted disruption of the endothelial nitric oxide synthase (NOS 3) gene
    • Steudel, W., F. Ichinose, P.L. Huang, W.E. Hurford, R.C. Jones, J.A. Bevan, M.C. Fishman, and W.M. Zapol. 1997. Pulmonary vasoconstriction and hypertension in mice with targeted disruption of the endothelial nitric oxide synthase (NOS 3) gene. Circ. Res. 81:34-41.
    • (1997) Circ. Res. , vol.81 , pp. 34-41
    • Steudel, W.1    Ichinose, F.2    Huang, P.L.3    Hurford, W.E.4    Jones, R.C.5    Bevan, J.A.6    Fishman, M.C.7    Zapol, W.M.8
  • 3
    • 0019443140 scopus 로고
    • Relationship between cyclic guanosine 3′:5′-monophosphate formation and relaxation of coronary arterial smooth muscle by glyceryl trinitrate, nitroprusside, nitrite and nitric oxide: Effects of methylene blue and methemoglobin
    • Gruetter, C.A., D.Y. Gruetter, J.E. Lyon, P.J. Kadowitz, and L.J. Ignarro. 1981. Relationship between cyclic guanosine 3′:5′-monophosphate formation and relaxation of coronary arterial smooth muscle by glyceryl trinitrate, nitroprusside, nitrite and nitric oxide: effects of methylene blue and methemoglobin. J. Pharmacol. Exp. Ther. 219:181-186.
    • (1981) J. Pharmacol. Exp. Ther. , vol.219 , pp. 181-186
    • Gruetter, C.A.1    Gruetter, D.Y.2    Lyon, J.E.3    Kadowitz, P.J.4    Ignarro, L.J.5
  • 4
    • 0028832852 scopus 로고
    • Endothelial nitric oxide synthase in the lungs of patients with pulmonary hypertension
    • Xue, C., and R.A. Johns. 1995. Endothelial nitric oxide synthase in the lungs of patients with pulmonary hypertension. N. Engl. J. Med. 333:1642-1644.
    • (1995) N. Engl. J. Med. , vol.333 , pp. 1642-1644
    • Xue, C.1    Johns, R.A.2
  • 5
    • 0023608815 scopus 로고
    • Vascular components of ARDS. Clinical pulmonary hemodynamics and morphology
    • Zapol, W.M., and R. Jones. 1987. Vascular components of ARDS. Clinical pulmonary hemodynamics and morphology. Am. Rev. Respir. Dis. 136:471-474.
    • (1987) Am. Rev. Respir. Dis. , vol.136 , pp. 471-474
    • Zapol, W.M.1    Jones, R.2
  • 6
    • 0017348501 scopus 로고
    • Vascular obstruction causes pulmonary hypertension in severe acute respiratory failure
    • Zapol, W.M., K. Kobayashi, M.T. Snider, R. Greene, and M.B. Laver. 1977. Vascular obstruction causes pulmonary hypertension in severe acute respiratory failure. Chest. 71:306-307.
    • (1977) Chest , vol.71 , pp. 306-307
    • Zapol, W.M.1    Kobayashi, K.2    Snider, M.T.3    Greene, R.4    Laver, M.B.5
  • 7
    • 0027370627 scopus 로고
    • Acute and prolonged hypoxia attenuate endothelial nitric oxide production in rat pulmonary arteries by different mechanisms
    • Shaul, P.W., L.B. Wells, and K.M. Horning. 1993. Acute and prolonged hypoxia attenuate endothelial nitric oxide production in rat pulmonary arteries by different mechanisms. J. Cardiovasc. Pharmacol. 22:819-827.
    • (1993) J. Cardiovasc. Pharmacol. , vol.22 , pp. 819-827
    • Shaul, P.W.1    Wells, L.B.2    Horning, K.M.3
  • 8
    • 0025963441 scopus 로고
    • Loss of endothelium-dependent relaxant activity in the pulmonary circulation of rats exposed to chronic hypoxia
    • Adnot, S., B. Raffestin, S. Eddahibi, P. Braquet, and P.E. Chabrier. 1991. Loss of endothelium-dependent relaxant activity in the pulmonary circulation of rats exposed to chronic hypoxia. J. Clin. Invest. 87:155-162.
    • (1991) J. Clin. Invest. , vol.87 , pp. 155-162
    • Adnot, S.1    Raffestin, B.2    Eddahibi, S.3    Braquet, P.4    Chabrier, P.E.5
  • 10
    • 0029957529 scopus 로고    scopus 로고
    • Upregulation of nitric oxide synthase correlates temporally with onset of pulmonary vascular remodeling in the hypoxic rat
    • Xue, C. and R.A. Johns. 1996. Upregulation of nitric oxide synthase correlates temporally with onset of pulmonary vascular remodeling in the hypoxic rat. Hypertension (Dallas). 28:743-753.
    • (1996) Hypertension (Dallas) , vol.28 , pp. 743-753
    • Xue, C.1    Johns, R.A.2
  • 11
    • 0027451371 scopus 로고
    • Chronic EDRF inhibition and hypoxia: Effects on pulmonary circulation and systemic blood pressure
    • Hampl, V., S.L. Archer, D.P. Nelson, and E.K. Weir. 1993. Chronic EDRF inhibition and hypoxia: effects on pulmonary circulation and systemic blood pressure. J. Appl. Physiol. 75:1748-1757.
    • (1993) J. Appl. Physiol. , vol.75 , pp. 1748-1757
    • Hampl, V.1    Archer, S.L.2    Nelson, D.P.3    Weir, E.K.4
  • 13
    • 0028954471 scopus 로고
    • Continuous nitric oxide inhalation reduces pulmonary arterial structural changes, right ventricular hypertrophy, and growth retardation in the hypoxic newborn rat
    • Roberts, J.D., Jr., C.T. Roberts, R.C. Jones, W.M. Zapol, and K.D. Bloch. 1995. Continuous nitric oxide inhalation reduces pulmonary arterial structural changes, right ventricular hypertrophy, and growth retardation in the hypoxic newborn rat. Circ. Res. 76:215-222.
    • (1995) Circ. Res. , vol.76 , pp. 215-222
    • Roberts Jr., J.D.1    Roberts, C.T.2    Jones, R.C.3    Zapol, W.M.4    Bloch, K.D.5
  • 14
    • 0030041523 scopus 로고    scopus 로고
    • Chronic inhaled nitric oxide: Effects on pulmonary vascular endothelial function and pathology in rats
    • Roos, C.M., D.U. Frank, C. Xue, R.A. Johns, and G.F. Rich. 1996. Chronic inhaled nitric oxide: effects on pulmonary vascular endothelial function and pathology in rats. J. Appl. Physiol. 80:252-260.
    • (1996) J. Appl. Physiol. , vol.80 , pp. 252-260
    • Roos, C.M.1    Frank, D.U.2    Xue, C.3    Johns, R.A.4    Rich, G.F.5
  • 15
    • 24444451464 scopus 로고    scopus 로고
    • Validation of three-dimensional transesophageal echocardiography for right ventricular volumes and function in mice
    • Abstr.
    • Scherrer-Crosbie, M., W. Steudel, G. Foster, W.M. Zapol, and M.H. Picard. 1997. Validation of three-dimensional transesophageal echocardiography for right ventricular volumes and function in mice. Circulation. 96:1698a. (Abstr.)
    • (1997) Circulation , vol.96
    • Scherrer-Crosbie, M.1    Steudel, W.2    Foster, G.3    Zapol, W.M.4    Picard, M.H.5
  • 16
    • 24444456738 scopus 로고    scopus 로고
    • Validation of transesophageal echocardiography for the assessment of right ventricular hypertrophy in the mouse
    • Abstr.
    • Scherrer-Crosbie, M., W. Steudel, G. Foster, W.M. Zapol, and M.H. Picard. 1997. Validation of transesophageal echocardiography for the assessment of right ventricular hypertrophy in the mouse. Circulation. 96:I699a. (Abstr.)
    • (1997) Circulation , vol.96
    • Scherrer-Crosbie, M.1    Steudel, W.2    Foster, G.3    Zapol, W.M.4    Picard, M.H.5
  • 18
    • 0027492948 scopus 로고
    • Loss of endothelium-dependent relaxation in proximal pulmonary arteries from rats exposed to chronic hypoxia: Effects of in vivo and in vitro supplementation with L-arginine
    • Carville, C., B. Raffestin, S. Eddahibi, Y. Blouquit, and S. Adnot. 1993. Loss of endothelium-dependent relaxation in proximal pulmonary arteries from rats exposed to chronic hypoxia: effects of in vivo and in vitro supplementation with L-arginine. J. Cardiovasc. Pharmacol. 22:889-896.
    • (1993) J. Cardiovasc. Pharmacol. , vol.22 , pp. 889-896
    • Carville, C.1    Raffestin, B.2    Eddahibi, S.3    Blouquit, Y.4    Adnot, S.5
  • 19
    • 0028608979 scopus 로고
    • Distribution of NOS in normoxic vs. hypoxic rat lung: Upregulation of NOS by chronic hypoxia
    • Xue, C., A. Rengasamy, T.D. Le Cras, P.A. Koberna, G.C. Dailey, and R.A. Johns. 1994. Distribution of NOS in normoxic vs. hypoxic rat lung: upregulation of NOS by chronic hypoxia. Am. J. Physiol. 267:L667-L678.
    • (1994) Am. J. Physiol. , vol.267
    • Xue, C.1    Rengasamy, A.2    Le Cras, T.D.3    Koberna, P.A.4    Dailey, G.C.5    Johns, R.A.6
  • 20
    • 0028095289 scopus 로고
    • Nitric oxide selectively amplifies FGF-2-induced mitogenesis in primary rat aortic smooth muscle cells
    • Hassid, A., H. Arabshahi, T. Bourcier, G.S. Dhaunsi, and C. Matthews. 1994. Nitric oxide selectively amplifies FGF-2-induced mitogenesis in primary rat aortic smooth muscle cells. Am. J. Physiol. 267:H1040-H1048.
    • (1994) Am. J. Physiol. , vol.267
    • Hassid, A.1    Arabshahi, H.2    Bourcier, T.3    Dhaunsi, G.S.4    Matthews, C.5
  • 21
    • 0027418979 scopus 로고
    • Inhaled nitric oxide selectively reverses human hypoxic pulmonary vasoconstriction without causing systemic vasodilation
    • Frostell, C.G., H. Blomqvist, G. Hedenstierna, J. Lundberg, and W.M. Zapol. 1993. Inhaled nitric oxide selectively reverses human hypoxic pulmonary vasoconstriction without causing systemic vasodilation. Anesthesiology. 78:427-435.
    • (1993) Anesthesiology , vol.78 , pp. 427-435
    • Frostell, C.G.1    Blomqvist, H.2    Hedenstierna, G.3    Lundberg, J.4    Zapol, W.M.5
  • 22
    • 0025910315 scopus 로고
    • Inhaled nitric oxide. A selective pulmonary vasodilator reversing hypoxic pulmonary vasoconstriction
    • Frostell, C., M.D. Fratacci, J.C. Wain, R. Jones, and W.M. Zapol. 1991. Inhaled nitric oxide. A selective pulmonary vasodilator reversing hypoxic pulmonary vasoconstriction. Circulation. 83:2038-2047.
    • (1991) Circulation , vol.83 , pp. 2038-2047
    • Frostell, C.1    Fratacci, M.D.2    Wain, J.C.3    Jones, R.4    Zapol, W.M.5
  • 23
    • 0028069803 scopus 로고
    • Continuous inhalation of nitric oxide protects against development of pulmonary hypertension in chronically hypoxic rats
    • Kouyoumdjian, C., S. Adnot, M. Levame, S. Eddahibi, H. Bousbaa, and B. Raffestin. 1994. Continuous inhalation of nitric oxide protects against development of pulmonary hypertension in chronically hypoxic rats. J. Clin. Invest. 94:578-584.
    • (1994) J. Clin. Invest. , vol.94 , pp. 578-584
    • Kouyoumdjian, C.1    Adnot, S.2    Levame, M.3    Eddahibi, S.4    Bousbaa, H.5    Raffestin, B.6
  • 26
    • 0024240198 scopus 로고
    • Pulmonary hypertension and right ventricular function in patients with COPD
    • Biernacki, W., D.C. Flenley, A.L. Muir, and W. MacNee. 1988. Pulmonary hypertension and right ventricular function in patients with COPD. Chest. 94:1169-1175.
    • (1988) Chest , vol.94 , pp. 1169-1175
    • Biernacki, W.1    Flenley, D.C.2    Muir, A.L.3    MacNee, W.4
  • 27
    • 0019947797 scopus 로고
    • Physiologic correlates of right ventricular ejection fraction in chronic obstructive pulmonary disease: A combined radionuclide and hemodynamic study
    • Brent, B.N., H.J. Berger, R.A. Matthay, D. Mahler, L. Pytlik, and B.L. Zaret. 1982. Physiologic correlates of right ventricular ejection fraction in chronic obstructive pulmonary disease: a combined radionuclide and hemodynamic study. Am. J. Cardiol. 50:255-262.
    • (1982) Am. J. Cardiol. , vol.50 , pp. 255-262
    • Brent, B.N.1    Berger, H.J.2    Matthay, R.A.3    Mahler, D.4    Pytlik, L.5    Zaret, B.L.6
  • 28
    • 0020647610 scopus 로고
    • Contribution of polycythaemia to pulmonary hypertension in simulated high altitude in rats
    • Barer, G.R., D. Bee, and R.A. Wach. 1983. Contribution of polycythaemia to pulmonary hypertension in simulated high altitude in rats. J. Physiol. (Lond). 336:27-38.
    • (1983) J. Physiol. (Lond) , vol.336 , pp. 27-38
    • Barer, G.R.1    Bee, D.2    Wach, R.A.3
  • 29
    • 0029905063 scopus 로고    scopus 로고
    • Nitric oxide modulation of pulmonary vascular resistance is red blood cell dependent in isolated rat lungs
    • Uncles, D.R., M.O. Daugherty, D.U. Frank, C.M. Roos, and G.F. Rich, 1996. Nitric oxide modulation of pulmonary vascular resistance is red blood cell dependent in isolated rat lungs. Anesth. Analg. 83:1212-1217.
    • (1996) Anesth. Analg. , vol.83 , pp. 1212-1217
    • Uncles, D.R.1    Daugherty, M.O.2    Frank, D.U.3    Roos, C.M.4    Rich, G.F.5
  • 30
    • 0030445908 scopus 로고    scopus 로고
    • ATP: The red blood cell link to NO and local control of the pulmonary circulation
    • Sprague, R.S., M.L. Ellsworth, A.H. Stephenson, and A.J. Lonigro. 1996. ATP: the red blood cell link to NO and local control of the pulmonary circulation. Am. J. Physiol. 271:H2717-H2722.
    • (1996) Am. J. Physiol. , vol.271
    • Sprague, R.S.1    Ellsworth, M.L.2    Stephenson, A.H.3    Lonigro, A.J.4
  • 31
    • 0031001489 scopus 로고    scopus 로고
    • Mechanotransduction in endothelial cells: Temporal signaling events in response to shear stress
    • Takahashi, M., T. Ishida, O. Traub, M.A. Carson, and B.C. Berk. 1997. Mechanotransduction in endothelial cells: temporal signaling events in response to shear stress. J. Vasc. Res. 34:212-219.
    • (1997) J. Vasc. Res. , vol.34 , pp. 212-219
    • Takahashi, M.1    Ishida, T.2    Traub, O.3    Carson, M.A.4    Berk, B.C.5
  • 33
    • 0028785441 scopus 로고
    • Nitric oxide enhancement of erythropoietin production in the isolated perfused rat kidney
    • Yoshioka, K., and J.W. Fisher. 1995. Nitric oxide enhancement of erythropoietin production in the isolated perfused rat kidney. Am. J. Physiol. 269: C917-C922.
    • (1995) Am. J. Physiol. , vol.269
    • Yoshioka, K.1    Fisher, J.W.2


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