Structure-function relations of the first and fourth predicted extracellular linkers of the type IIa Na+/Pi cotransporter: I. Cysteine scanning mutagenesis

Journal of General Physiology

Volumn 124, Issue 5, 2004, Pages 475-488

  Ehnes, Colin ^a   Forster, Ian C ^a   Kohler, Katja ^a,b   Bacconi, Andrea ^a   Stange, Gerti ^a   Biber, Jürg ^a   Murer, Heini ^a  

^a UNIVERSITY OF ZURICH   (Switzerland)

^b INSTITUT CURIE   (France)

Author keywords

Electrogenic Xenopus laevis; Electrophysiology; Mutagenesis site directed; Phosphate transport proteins

Indexed keywords

COTRANSPORTER; CYSTEINE; GLYCINE; METHANETHIOSULFONATE; REAGENT; SODIUM PHOSPHATE COTRANSPORTER; SULFONIC ACID DERIVATIVE; UNCLASSIFIED DRUG;

AMINO ACID SUBSTITUTION; ANIMAL CELL; ARTICLE; CELL MEMBRANE TRANSPORT; CONFORMATIONAL TRANSITION; CONTROLLED STUDY; CYSTEINE SCANNING MUTAGENESIS; DELETION MUTANT; ELECTRIC POTENTIAL; ELECTROPHYSIOLOGY; HYPERPOLARIZATION; KINETICS; MEMBRANE CURRENT; MEMBRANE POTENTIAL; MUTAGENESIS; NONHUMAN; PROTEIN DOMAIN; STRUCTURE ANALYSIS; WILD TYPE; XENOPUS;

AMINO ACID SEQUENCE; ANIMALS; CELL MEMBRANE; CELLS, CULTURED; CYSTEINE; DOSE-RESPONSE RELATIONSHIP, DRUG; EXTRACELLULAR FLUID; MEMBRANE POTENTIALS; MESYLATES; MOLECULAR SEQUENCE DATA; MUTAGENESIS, SITE-DIRECTED; OOCYTES; PHOSPHATES; PROTEIN SUBUNITS; RECOMBINANT PROTEINS; SODIUM-PHOSPHATE COTRANSPORTER PROTEINS; STRUCTURE-ACTIVITY RELATIONSHIP; SYMPORTERS; XENOPUS LAEVIS;

EID: 8644251283     PISSN: 00221295     EISSN: None     Source Type: Journal    
DOI: 10.1085/jgp.200409060     Document Type: Article

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