Structure-function relations of the first and fourth extracellular linkers of the type IIa Na+/Pi cotransporter: II. Substrate interaction and voltage dependency of two functionally important sites

Journal of General Physiology

Volumn 124, Issue 5, 2004, Pages 489-503

  Ehnes, Colin ^a   Forster, Ian C ^a   Bacconi, Andrea ^a   Kohler, Katja ^a,b   Biber, Jürg ^a   Murer, Heini ^a  

^a UNIVERSITY OF ZURICH   (Switzerland)

^b INSTITUT CURIE   (France)

Author keywords

Cysteine; Electrophysiology; Mutagenesis site directed; Phosphate transport proteins; Transport model

Indexed keywords

COTRANSPORTER; CYSTEINE; GLYCINE; METHANETHIOSULFONATE; METHIONINE; REAGENT; SODIUM PHOSPHATE COTRANSPORTER; SULFONIC ACID DERIVATIVE; UNCLASSIFIED DRUG;

AMINO ACID SUBSTITUTION; ARTICLE; CONFORMATIONAL TRANSITION; CYSTEINE SCANNING MUTAGENESIS; DELETION MUTANT; ELECTRIC POTENTIAL; EXPOSURE; HYPERPOLARIZATION; KINETICS; MODEL; MUTAGENESIS; PROTON TRANSPORT; STEADY STATE; STRUCTURE ANALYSIS;

AMINO ACID SEQUENCE; ANIMALS; CELL MEMBRANE; CELLS, CULTURED; CYSTEINE; DOSE-RESPONSE RELATIONSHIP, DRUG; EXTRACELLULAR FLUID; MEMBRANE POTENTIALS; MESYLATES; MOLECULAR SEQUENCE DATA; MUTAGENESIS, SITE-DIRECTED; OOCYTES; PHOSPHATES; PROTEIN SUBUNITS; RECOMBINANT PROTEINS; SODIUM-PHOSPHATE COTRANSPORTER PROTEINS; STRUCTURE-ACTIVITY RELATIONSHIP; SYMPORTERS; XENOPUS LAEVIS;

EID: 8644275445     PISSN: 00221295     EISSN: None     Source Type: Journal    
DOI: 10.1085/jgp.200409061     Document Type: Article

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