Transport function of the renal type IIa Na+/Pi cotransporter is codetermined by residues in two opposing linker regions

Journal of General Physiology

Volumn 120, Issue 5, 2002, Pages 693-705

  Köhler, Katja ^a   Forster, Ian C ^a   Stange, Gerti ^a   Biber, Jürg ^a   Murer, Heini ^a  

^a UNIVERSITY OF ZURICH   (Switzerland)

Author keywords

Cysteine mutagenesis; Electrophysiology; Leak current; Pi cotransport; Structure function

Indexed keywords

2 (TRIMETHYLAMMONIUM)ETHYLMETHANETHIOSULFONATE BROMIDE; 2 AMINOETHYLMETHANETHIOSULFONATE HYDROBROMIDE; BROMINE DERIVATIVE; CELL PROTEIN; COTRANSPORTER; CYSTEINE; METHANETHIOSULFONATE ETHYLSULFONATE; PROTEIN ECL 3; PROTEIN ICL 1; SODIUM DIHYDROGEN PHOSPHATE; THIOMESYLIC ACID METHYL ESTER; UNCLASSIFIED DRUG; PHOSPHATE; SODIUM PHOSPHATE COTRANSPORTER;

ANIMAL CELL; ARTICLE; CONTROLLED STUDY; ELECTROPHYSIOLOGY; HYDROPHILICITY; HYDROPHOBICITY; ION CURRENT; KIDNEY FUNCTION; KIDNEY TUBULE ABSORPTION; KINETICS; MUTAGENESIS; NONHUMAN; PROTEIN FUNCTION; PROTEIN MODIFICATION; STOICHIOMETRY; STRUCTURE ACTIVITY RELATION; ACTIVE TRANSPORT; AMINO ACID SUBSTITUTION; ANIMAL; CELL MEMBRANE POTENTIAL; CHEMISTRY; GENETICS; ION TRANSPORT; METABOLISM; MICROVILLUS; OOCYTE; PHYSIOLOGY; PROTEIN CONFORMATION; SITE DIRECTED MUTAGENESIS; XENOPUS LAEVIS;

AMINO ACID SUBSTITUTION; ANIMALS; BIOLOGICAL TRANSPORT, ACTIVE; CYSTEINE; ION TRANSPORT; KINETICS; MEMBRANE POTENTIALS; MICROVILLI; MUTAGENESIS, SITE-DIRECTED; OOCYTES; PHOSPHATES; PROTEIN CONFORMATION; SODIUM-PHOSPHATE COTRANSPORTER PROTEINS; STRUCTURE-ACTIVITY RELATIONSHIP; SYMPORTERS; XENOPUS LAEVIS;

EID: 0036845676     PISSN: 00221295     EISSN: None     Source Type: Journal    
DOI: 10.1085/jgp.20028645     Document Type: Article

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