Formaldehyde-induced DNA adducts as biomarkers of in vitro human nasal epithelial cell exposure to formaldehyde

Mutation Research - Genetic Toxicology and Environmental Mutagenesis

Volumn 563, Issue 1, 2004, Pages 13-24

  Zhong, Weiguang ^a   Que Hee, Shane S ^a  

^a UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

DNA adducts; Formaldehyde; HPLC UV; Human nasal epithelial cells; Hydroxymethyldeoxynucleosides; Mutation

Indexed keywords

BIOLOGICAL MARKER; DEOXYRIBONUCLEOTIDE; FORMALDEHYDE; FIXATIVE; MUTAGENIC AGENT;

ARTICLE; BIOLOGICAL MONITORING; CELL VIABILITY; CONCENTRATION RESPONSE; CONTROLLED STUDY; DNA ADDUCT; DNA DETERMINATION; DNA ISOLATION; ENZYME ASSAY; EPITHELIUM CELL; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; HUMAN; HUMAN CELL; NOSE MUCOSA; NOSE MUCUS; PRIORITY JOURNAL; QUANTITATIVE ANALYSIS; SAMPLING; ULTRAVIOLET RADIATION; ANIMAL; CELL CULTURE; CELL SURVIVAL; CHEMICALLY INDUCED DISORDER; CYTOLOGY; DRUG EFFECT; ENVIRONMENTAL EXPOSURE; GENETICS; MALE; METABOLISM; METHODOLOGY; NOSE TUMOR; RAT;

ANIMALS; BIOLOGICAL MARKERS; CELL SURVIVAL; CELLS, CULTURED; CHROMATOGRAPHY, HIGH PRESSURE LIQUID; DNA ADDUCTS; ENVIRONMENTAL EXPOSURE; FIXATIVES; FORMALDEHYDE; HUMANS; MALE; MUTAGENS; NASAL MUCOSA; NOSE NEOPLASMS; RATS;

EID: 8644224857     PISSN: 13835718     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.mrgentox.2004.05.012     Document Type: Article

References (48)

1. World Health Organization (WHO), Formaldehyde, Environmental Health Criteria 89, WHO, Geneva, 1989.
2. US Department of Health and Human Services, Toxicological Profile for Formaldehyde, Agency for Toxic Substances and Disease Registry, Atlanta, 1999.
3. Swenberg J.A., Kerns W.D., Mitchell R.I., Gralla E.J., Pavkov K.L. Induction of squamous cell carcinomas of the rat nasal cavity by inhalation exposure to formaldehyde vapor. Cancer Res. 40:1980;3398-3402
4. Swenberg J.A., Barrow S., Boreiko C.J., Levin R.J., Morgan K.T., Starr T.B. Non-linear biological responses to formaldehyde and their implications for carcinogenic risk assessment. Carcinogenesis. 4:1983;945-952
5. Kerns W.D., Pavkov K.L., Swenberg J.A. Carcinogenicity of formaldehyde in rats and mice after long-term inhalation exposure. Cancer Res. 43:1983;4382-4392
6. Olsen J.H., Asnaes S. Formaldehyde and the risk of squamous cell carcinoma of the sinonasal cavities. Br. J. Ind. Med. 43:1986;769-774
7. Hansen J., Olson J.H. Formaldehyde and cancer morbidity among male employees in Denmark. Cancer Causes Control. 6:1995;354-360
8. Vaughan T.L., Stewart P.A., Teschke K., Berwick M. Occupational exposure to formaldehyde and wood dust and nasopharyngeal carcinoma. Occup. Environ. Med. 57:2000;376-384
9. Wilbourn J., Heseltine E., Moller H. IARC evaluates wood dust and formaldehyde. Scand. J. Work Environ. Health. 21:1995;229-232
10. Berrino F., Richiardi L., Boffetta P., Esteve J., Belletti I., Raymond L., Troschel L., Pisani P., Zubiri L., Ascunce N., Guberan E., Tuyns A., Terracini B., Merletti F. Milan JEM Working Group Occupation and larynx and hypopharynx cancer: a job-exposure matrix approach in an international case-control study in France, Italy, Spain and Switzerland. Cancer Causes Control. 14:2003;213-223
11. Hauptmann M., Lubin J.H., Stewart P.A., Hayes R.B., Blair A. Mortality from lymphohematopoietic malignancies among workers in formaldehyde industries. J. Natl. Cancer Inst. 95:2003;1615-1623
12. Coggon D., Harris E.C., Poole J., Palmer K.T. Extended follow-up of a cohort of British chemical workers exposed to formaldehyde. J. Natl. Cancer Inst. 95:2003;1608-1615
13. Shaham J., Gurvich R., Kaufman Z. Sister chromatid exchange in pathology staff occupationally exposed to formaldehyde. Mutat. Res. 514:2002;115-123
14. Morgan K.T. A brief review of formaldehyde carcinogenesis in relation to rat nasal pathology and human health risk assessment. Toxicol. Pathol. 25:1997;291-307
15. Gottschling L.M., Beaulieu H.J., Melvin W.W. Monitoring of formic acid in urine of humans exposed to low levels of formaldehyde. Am. Ind. Hyg. Assoc. J. 45:1984;19-23
16. H. Marquardt, S.S. Schafer, R.O. McClellan, F. Welsch, Toxicology, Academic Press, San Diego, 1999, p. 636.
17. Shaham J., Bomstein Y., Gurvich R., Rashkovsky M., Kaufman Z. DNA-protein crosslinks and p53 protein expression in relation to occupational exposure to formaldehyde. Occup. Environ. Med. 60:2003;403-409
18. Feron V.J., Til H.P., De Vrijer F., Woutersen R.A., Cassee F.R., Van Bladeren P.J. Aldehydes: occurrence, carcinogenic potential, mechanism of action and risk assessment. Mutat. Res. 259:1991;363-385
19. Fennell T.R. Development of methods for measuring biological markers of formaldehyde exposure. Health Eff. Inst. Res. Rep. 67:1994;1-25
20. S.S. Que Hee, DNA adducts, in: S.S. Que Hee (Ed.), Biological Monitoring, Van Nostrand Reinhold, New York, 1993, p. 320.
21. Feldman M.Y. Reaction of formaldehyde with nucleotides and ribonucleic acid. Biochim. Biophys. Acta. 149:1973;20-34
22. Beland F.A., Fullerton N.F., Heflich R.H. Rapid isolation, hydrolysis and chromatography of formaldehyde-modified DNA. J. Chromatogr. 308:1984;121-131
23. Casanova M., Deyo D.F., Heck H. Covalent binding of inhaled formaldehyde to DNA in the nasal mucosa of Fischer 344 rats: analysis of formaldehyde and DNA by HPLC and provisional pharmacokinetic interpretation. Fundam. Appl. Toxicol. 12:1989;397-417
24. Cheng G., Shi Y., Sturla S.J., Jalas J.R., McIntee E.J., Villalta P.W., Wang M., Hecht S.S. Reactions of formaldehyde plus acetaldehyde with deoxyguanosine and DNA: formation of cyclic deoxyguanosine adducts and formaldehyde cross-links. Chem. Res. Toxicol. 16:2003;145-152
25. W. Zhong, S.S. Que Hee, Quantitation of normal and formaldehyde-modified deoxynucleosides by HPLC/UV detection, Biomed. Chromatogr. 18 (2004), in press.
26. Rasouli A., Sun C.H., Basu R., Wong B.J. Quantitative assessment of chondrocyte viability after laser mediated reshaping: a novel application of flow cytometry. Lasers Surgery Med. 32:2003;3-9
27. Shen Y., Que Hee S.S. Optimization of a solid sorbent dynamic personal air sampling method for aldehydes. Appl. Occup. Environ. Hyg. 15:2000;228-234
28. Cancilla D.A., Chou C.C., Barthel R., Que Hee S.S. Characterization of the O-(2,3,4,5,6-pentafluorophenyl)hydroxylamine hydrochloride (PFBHA) derivatives of some aliphatic mono- and di-aldehydes and quantitative water analysis of these aldehydes. J. Assoc. Offic. Anal. Chem. Int. 75:1992;842-854
29. Bridge M.A., Bavidson A.G.F., Walker D.C. Cystic fibrosis and control nasal epithelial cells harvested by a brushing procedure. In Vitro Cell Dev. Biol. 27A:1991;684-686
30. Wu R., Yankaskas J., Cheng E., Boucher R. Growth and differentiation of human nasal epithelial cells in culture. Serum-free, hormone-supplemented medium and proteoglycan synthesis. Am. Rev. Respir. Dis. 132:1985;311-320
31. Huber J.D., Hau V.S., Mark K.S., Brown R.C., Campos C.R., Davis T.P. Viability of microvascular endothelial cells to direct exposure of formalin, λ-carrageenan, and complete Freund's adjuvant. Eur. J. Pharmacol. 450:2002;297-304
32. Vock E.H., Lutz W.K., Ilinskaya O., Vamvakas S. Discrimination between genotoxicity and cytotoxicity for the induction of DNA double-strand breaks in cells treated with aldehydes and diepoxides. Mutat. Res. 441:1999;85-93
33. Goldmacher V.S., Thilly W.G. Formaldehyde is mutagenic for cultured human cells. Mutat. Res. 116:1983;417-422
34. Craft T.R., Bermudez E., Skopek T.R. Formaldehyde mutagenesis and formation of DNA-protein crosslinks in human lymphoblasts in vitro. Mutat. Res. 176:1987;147-155
35. ± assay supplemented with formaldehyde dehydrogenase. In Vitro Toxicol. 4:1991;121-132
36. Merk O., Speit G. Significance of formaldehyde-induced DNA-protein crosslinks for mutagenesis. Environ. Mol. Mutagen. 32:1998;260-268
37. Merk O., Speit G. Detection of crosslinks with the comet assay in relationship to genotoxicity and cytotoxicity. Environ. Mol. Mutagen. 33:1999;167-172
38. Speit G., Merk O. Evaluation of mutagenic effects of formaldehyde in vitro: detection of crosslinks and mutations in mouse lymphoma cells. Mutagenesis. 17:2002;183-187
39. Conolly R.B., Kimbell J.S., Janszen D., Schlosser P.M., Kalisak D., Preston J., Miller F.J. Biologically motivated computational modeling of formaldehyde carcinogenicity in the F344 rat. Toxicol. Sci. 75:2003;432-447
40. Hester S.D., Benavides G.B., Yoon L., Morgan K.T., Zou F., Barry W., Wolf D.C. Formaldehyde-induced gene expression in F344 rat nasal respiratory epithelium. Toxicology. 187:2003;13-24
41. Monticello T.M., Miller F.J., Morgan K.T. Regional increases in rat epithelial cell proliferation following acute and subchronic inhalation of formaldehyde. Toxicol. Appl. Chromatogr. 111:1991;409-421
42. Butterworth B.E., Conolly R.B., Morgan K.T. A strategy for establishing mode of action of chemical carcinogens as a guide for approaches to risk assessments. Cancer Lett. 93:1995;129-146
43. Adimoolam S., Ford J.M. p53 and regulation of DNA damage recognition during nucleotide excision repair. DNA Repair (Amsterdam). 2:2003;947-954
44. Oren M. Decision making by p53: life, death and cancer. Cell Death Differ. 10:2003;431-442
45. Singh R., McEwan M., Lamb J.H., Santella R.M., Farmer P.B. An improved liquid chromatography/tandem mass spectrometry method for the determination of 8-oxo-7,8-dihydro-2′-deoxyguanosine in DNA samples using immunoaffinity column purification. Rapid Commun. Mass Spectrom. 17:2003;126-134
46. El-Osta A. DNMT cooperativity - the developing links between methylation, chromatin structure and cancer. Bioessays. 25:2003;1071-1084
47. Pipkorn U., Karlsson G. Methods for obtaining specimens from the nasal mucosa for morphological and biochemical analysis. Eur. Respir. J. 1:1988;856-862
48. Steerenberg P.A., Fischer P.H., van Bree L., van Loveren H. Nasal lavage biomarkers in air pollution epidemiology. Arch. Toxicol. Suppl. 19:1997;207-216