Biophysical characterization of zebrafish connexin35 hemichannels

American Journal of Physiology - Cell Physiology

Volumn 287, Issue 6 56-6, 2004, Pages

  Valiunas, Virginijus ^a   Mui, Rickie ^a   McLachlan, Elizabeth ^b   Valdimarsson, Gunnar ^b   Brink, Peter R ^a   White, Thomas W ^a  

^a STONY BROOK UNIVERSITY   (United States)

^b UNIVERSITY OF MANITOBA   (Canada)

Author keywords

Connexin; Gating; Retina

Indexed keywords

CONNEXIN 35; GAP JUNCTION PROTEIN; UNCLASSIFIED DRUG;

ANIMAL CELL; ARTICLE; CELL MEMBRANE POTENTIAL; CELL STRAIN; CHANNEL GATING; COMPARATIVE STUDY; CONTROLLED STUDY; HYPERPOLARIZATION; NONHUMAN; OOCYTE; PRIORITY JOURNAL; PROTEIN EXPRESSION; RAT; XENOPUS; ZEBRA FISH;

ANIMALS; CONNEXINS; EYE PROTEINS; GAP JUNCTIONS; ION CHANNEL GATING; KINETICS; MEMBRANE POTENTIALS; OLIGONUCLEOTIDES, ANTISENSE; OOCYTES; PATCH-CLAMP TECHNIQUES; PROTEIN STRUCTURE, QUATERNARY; RNA, COMPLEMENTARY; TRANSFECTION; XENOPUS; ZEBRAFISH;

ANIMALIA; DANIO RERIO;

EID: 8644223289     PISSN: 03636143     EISSN: None     Source Type: Journal    
DOI: 10.1152/ajpcell.00225.2004     Document Type: Article

References (60)

1. Bao X, Altenberg GA, and Reuss L. Mechanism of regulation of the gap junction protein connexin 43 by protein kinase C-mediated phosphorylation. Am J Physiol Cell Physiol 286: C647-C654, 2004.
2. Beahm DL and Hall JE. Hemichannel and junctional properties of connexin 50. Biophys J 82: 2016-2031, 2002.
3. Bennett MV, Contreras JE, Bukauskas FF, and Saez JC. New roles for astrocytes: gap junction hemichannels have something to communicate. Trends Neurosci 26: 610-617, 2003.
4. Bruzzone R, Hormuzdi SG, Barbe MT, Herb A, and Monyer H. Pannexins, a family of gap junction proteins expressed in brain. Proc Natl Acad Sci USA 100: 13644-13649, 2003.
5. Bruzzone R, White TW, and Paul DL. Connections with connexins: the molecular basis of direct intercellular signaling. Eur J Biochem 238: 1-27, 1996.
6. Bukauskas FF and Verselis VK. Gap junction channel gating. Biochim Biophys Acta 1662: 42-60, 2004.
7. Contreras JE, Saez JC, Bukauskas FF, and Bennett MV. Functioning of Cx43 hemichannels demonstrated by single channel properties. Cell Commun Adhes 10: 245-249, 2003.
8. Dermietzel R, Kremer M, Paputsoglu G, Stang A, Skerrett IM, Gomes D, Srinivas M, Janssen-Bienhold U, Weiler R, Nicholson BJ, Bruzzone R, and Spray DC. Molecular and functional diversity of neural connexins in the retina. J Neurosci 20: 8331-8343, 2000.
9. DeVries SH and Schwartz EA. Hemi-gap-junction channels in solitary horizontal cells of the catfish retina. J Physiol 445: 201-230, 1992.
10. Ebihara L. Xenopus connexin38 forms hemi-gap-junctional channels in the nonjunctional plasma membrane of Xenopus oocytes. Biophys J 71: 742-748, 1996.
11. Ebihara L. New roles for connexons. News Physiol Sci 18: 100-103, 2003.
12. Ebihara L, Berthoud VM, and Beyer EC. Distinct behavior of connexin56 and connexin46 gap junctional channels can be predicted from the behavior of their hemi-gap-junctional channels. Biophys J 68: 1796-1803, 1995.
13. Ebihara L, Liu X, and Pal JD. Effect of external magnesium and calcium on human connexin46 hemichannels. Biophys J 84: 277-286, 2003.
14. Ebihara L and Steiner E. Properties of a nonjunctional current expressed from a rat connexin46 cDNA in Xenopus oocytes. J Gen Physiol 102: 59-74, 1993.
15. Evans WH and Martin PE. Gap junctions: structure and function. Mol Membr Biol 19: 121-136, 2002.
16. Feigenspan A, Janssen-Bienhold U, Hormuzdi S, Monyer H, Degen J, Sohl G, Willecke K, Ammermuller J, and Weiler R. Expression of connexin36 in cone pedicles and OFF-cone bipolar cells of the mouse retina. J Neurosci 24: 3325-3334, 2004.
17. Feigenspan A, Teubner B, Willecke K, and Weiler R. Expression of neuronal connexin36 in AII amacrine cells of the mammalian retina. J Neurosci 21: 230-239, 2001.
18. Gomez-Hernandez JM, de Miguel M, Larrosa B, Gonzalez D, and Barrio LC. Molecular basis of calcium regulation in connexin-32 hemichannels. Proc Natl Acad Sci USA 100: 16030-16035, 2003.
19. Goodenough DA. Bulk isolation of mouse hepatocyte gap junctions. Characterization of the principal protein, connexin. J Cell Biol 61: 557-563, 1974.
20. Goodenough DA and Paul DL. Beyond the gap: functions of unpaired connexon channels. Nat Rev Mol Cell Biol 4: 285-294, 2003.
21. Guldenagel M, Ammermuller J, Feigenspan A, Teubner B, Degen J, Sohl G, Willecke K, and Weiler R. Visual transmission deficits in mice with targeted disruption of the gap junction gene connexin36. J Neurosci 21: 6036-6044, 2001.
22. Guldenagel M, Sohl G, Plum A, Traub O, Teubner B, Weiler R, and Willecke K. Expression patterns of connexin genes in mouse retina. J Comp Neurol 425: 193-201, 2000.
23. Harris AL. Emerging issues of connexin channels: biophysics fills the gap. Q Rev Biophys 34: 325-472, 2001.
24. 2 by osteocytes in response to mechanical strain. Cell Commun Adhes 10: 259-264, 2003.
25. Kamermans M, Fahrenfort I, Schultz K, Janssen-Bienhold U, Sjoerdsma T, and Weiler R. Hemichannel-mediated inhibition in the outer retina. Science 292: 1178-1180, 2001.
26. Krisciukaitis A. Computer programs for investigation of intercellular communication using double whole cell voltage clamp. Electron Elect Eng 4: 71-83, 1997.
27. Lee EJ, Han JW, Kim HJ, Kim IB, Lee MY, Oh SJ, Chung JW, and Chun MH. The immunocytochemical localization of connexin 36 at rod and cone gap junctions in the guinea pig retina. Eur J Neurosci 18: 2925-2934, 2003.
28. Malchow RP, Qian H, and Ripps H. Evidence for hemi-gap junctional channels in isolated horizontal cells of the skate retina. J Neurosci Res 35: 237-245, 1993.
29. McLachlan E, White TW, Ugonabo C, Olson C, Nagy JI, and Valdimarsson G. Zebrafish Cx35: cloning and characterization of a gap junction gene highly expressed in the retina. J Neurosci Res 73: 753-764, 2003.
30. Meier C, Petrasch-Parwez E, Habbes HW, Teubner B, Guldenagel M, Degen J, Sohl G, Willecke K, and Dermietzel R. Immunohistochemical detection of the neuronal connexin36 in the mouse central nervous system in comparison to connexin36-deficient tissues. Histochem Cell Biol 117: 461-471, 2002.
31. Mills SL, O'Brien JJ, Li W, O'Brien J, and Massey SC. Rod pathways in the mammalian retina use connexin 36. J Comp Neurol 436: 336-350, 2001.
32. Mitropoulou G and Bruzzone R. Modulation of perch connexin35 hemi-channels by cyclic AMP requires a protein kinase A phosphorylation site. J Neurosci Res 72: 147-157, 2003.
33. Neyton J and Trautmann A. Single-channel currents of an intercellular junction. Nature 317: 331-335, 1985.
34. Nicholson BJ, Hunkapiller MW, Grim LB, Hood LE, and Revel JP. Rat liver gap junction protein: properties and partial sequence. Proc Natl Acad Sci USA 78: 7594-7598, 1981.
35. O'Brien J, Al Ubaidi MR, and Ripps H. Connexin 35: a gap-junctional protein expressed preferentially in the skate retina. Mol Biol Cell 7: 233-243, 1996.
36. O'Brien J, Bruzzone R, White TW, Al Ubaidi MR, and Ripps H. Cloning and expression of two related connexins from the perch retina define a distinct subgroup of the connexin family. J Neurosci 18: 7625-7637, 1998.
37. Pereda A, O'Brien J, Nagy JI, Bukauskas F, Davidson KG, Kamasawa N, Yasumura T, and Rash JE. Connexin35 mediates electrical transmission at mixed synapses on Mauthner cells. J Neurosci 23: 7489-7503, 2003.
38. Pereda A, O'Brien J, Nagy JI, Smith M, Bukauskas F, Davidson KG, Kamasawa N, Yasumura T, and Rash JE. Short-range functional interaction between connexin35 and neighboring chemical synapses. Cell Commun Adhes 10: 419-423, 2003.
39. Pfahnl A and Dahl G. Localization of a voltage gate in connexin46 gap junction hemichannels. Biophys J 75: 2323-2331, 1998.
40. Pottek M, Hoppenstedt W, Janssen-Bienhold U, Schultz K, Perlman I, and Weiler R. Contribution of connexin26 to electrical feedback inhibition in the turtle retina. J Comp Neurol 466: 468-477, 2003.
41. Saez JC, Berthoud VM, Branes MC, Martinez AD, and Beyer EC. Plasma membrane channels formed by connexins: their regulation and functions. Physiol Rev 83: 1359-1400, 2003.
42. Sohl G and Willecke K. An update on connexin genes and their nomenclature in mouse and man. Cell Commun Adhes 10: 173-180, 2003.
43. Spray DC, Harris AL, and Bennett MV. Equilibrium properties of a voltage-dependent junctional conductance. J Gen Physiol 77: 77-93, 1981.
44. Srinivas M, Rozental R, Kojima T, Dermietzel R, Mehler M, Condorelli DF, Kessler JA, and Spray DC. Functional properties of channels formed by the neuronal gap junction protein connexin36. J Neurosci 19: 9848-9855, 1999.
45. Teubner B, Degen J, Sohl G, Guldenagel M, Bukauskas FF, Trexler EB, Verselis VK, De Zeeuw CI, Lee CG, Kozak CA, Petrasch-Parwez E, Dermietzel R, and Willecke K. Functional expression of the murine connexin 36 gene coding for a neuron-specific gap junctional protein. J Membr Biol 176: 249-262, 2000.
46. Trexler EB, Bennett MV, Bargiello TA, and Verselis VK. Voltage gating and permeation in a gap junction hemichannel. Proc Natl Acad Sci USA 93: 5836-5841, 1996.
47. Trexler EB and Verselis VK. The study of connexin hemichannels (connexons) in Xenopus oocytes. Methods Mol Biol 154: 341-355, 2001.
48. Turner DL and Weintraub H. Expression of achaete-scute homolog 3 in Xenopus embryos converts ectodermal cells to a neural fate. Genes Dev 8: 1434-1447, 1994.
49. Valiunas V. Biophysical properties of connexin-45 gap junction hemichannels studied in vertebrate cells. J Gen Physiol 119: 147-164, 2002.
50. Valiunas V, Beyer EC, and Brink PR. Cardiac gap junction channels show quantitative differences in selectivity. Circ Res 91: 104-111, 2002.
51. Valiunas V and Weingart R. Electrical properties of gap junction hemichannels identified in transfected HeLa cells. Pflügers Arch 440: 366-379, 2000.
52. Vergara L, Bao X, Bello-Reuss E, and Reuss L. Do connexin 43 gap-junctional hemichannels activate and cause cell damage during ATP depletion of renal-tubule cells? Acta Physiol Scand 179: 33-38, 2003.
53. Vessey JP, Lalonde MR, Mizan HA, Welch NC, Kelly ME, and Barnes S. Carbenoxolone inhibition of voltage-gated Ca channels and synaptic transmission in the retina. J Neurophysiol 92: 1252-1256, 2004.
54. Wagner TL, Beyer EC, and McMahon DG. Cloning and functional expression of a novel gap junction channel from the retina of Danio aquipinnatus. Vis Neurosci 15: 1137-1144, 1998.
55. White TW, Deans MR, O'Brien J, Al Ubaidi MR, Goodenough DA, Ripps H, and Bruzzone R. Functional characteristics of skate connexin35, a member of the γ subfamily of connexins expressed in the vertebrate retina. Eur J Neurosci 11: 1883-1890, 1999.
56. White TW, Ripps H, Srinivas M, and Bruzzone R. Voltage gating properties of channels formed by a skate retinal connexin. Biol Bull 199: 165-168, 2000.
57. Willecke K, Eiberger J, Degen J, Eckardt D, Romualdi A, Guldenagel M, Deutsch U, and Sohl G. Structural and functional diversity of connexin genes in the mouse and human genome. Biol Chem 383: 725-737, 2002.
58. Zhang J and Wu SM. Connexin35/36 gap junction proteins are expressed in photoreceptors of the tiger salamander retina. J Comp Neurol 470: 1-12, 2004.
59. Zoidl G, Bruzzone R, Weickert S, Kremer M, Zoidl C, Mitropoulou G, Srinivas M, Spray DC, and Dermietzel R. Molecular cloning and functional expression of zfCx52.6: a novel connexin with hemichannel-forming properties expressed in horizontal cells of the zebrafish retina. J Biol Chem 279: 2913-2921, 2004.
60. Zoidl G and Dermietzel R. On the search for the electrical synapse: a glimpse at the future. Cell Tissue Res 310: 137-142, 2002.