Zebrafish Cx35: Cloning and characterization of a gap junction gene highly expressed in the retina

Journal of Neuroscience Research

Volumn 73, Issue 6, 2003, Pages 753-764

  McLachlan, Elizabeth ^a   White, Thomas W ^b   Ugonabo, Chioma ^b   Olson, Carl ^a   Nagy, James I ^a   Valdimarsson, Gunnar ^a  

^a UNIVERSITY OF MANITOBA   (Canada)

^b NONE

Author keywords

Connexin; Embryo; Gap junction; Intercellular communication; Retina; Vision; Zebrafish

Indexed keywords

CONNEXIN 35; GAP JUNCTION PROTEIN; UNCLASSIFIED DRUG;

AMINO ACID SEQUENCE; ANIMAL BEHAVIOR; ANIMAL CELL; ANIMAL EXPERIMENT; ARTICLE; ARTIFICIAL CHROMOSOME; CONTROLLED STUDY; ELECTRIC POTENTIAL; FERTILIZATION; GAP JUNCTION; GENE EXPRESSION; GENETIC CODE; IMMUNOHISTOCHEMISTRY; MOLECULAR CLONING; MOUSE; MULTIGENE FAMILY; NONHUMAN; NORTHERN BLOTTING; PRIORITY JOURNAL; PROTEIN EXPRESSION; RETINA; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; VERTEBRATE; VISUAL SYSTEM; ZEBRA FISH;

ANIMALS; BLOTTING, NORTHERN; BLOTTING, WESTERN; BRAIN; BRAIN CHEMISTRY; CLONING, MOLECULAR; CONNEXINS; ELECTROPHYSIOLOGY; EVOLUTION, MOLECULAR; EYE PROTEINS; GAP JUNCTIONS; IMMUNOHISTOCHEMISTRY; LIVER; MICE; MOLECULAR SEQUENCE DATA; OOCYTES; RETINA; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; RNA, MESSENGER; SEQUENCE HOMOLOGY, AMINO ACID; TIME FACTORS; XENOPUS; ZEBRAFISH; ZEBRAFISH PROTEINS;

EID: 0042839653     PISSN: 03604012     EISSN: None     Source Type: Journal    
DOI: 10.1002/jnr.10712     Document Type: Article

References (51)

1. Al-Ubaidi MR, White TW, Ripps H, Poras I, Avner P, Gomes D, Bruzzone R. 2000. Functional properties, developmental regulation, and chromosomal localization of murine connexin 36, a gap-junctional protein expressed preferentially in retina and brain. J Neurosci Res 59:813-826.
2. Altevogt BM, Kleopa KA, Postma FR, Scherer SS, Paul DL. 2002. Connexin29 is uniquely distributed within myelinating glial cells of the central and peripheral nervous systems. J Neurosci 22:6458-6470.
3. Amemiya CT, Zhong TP, Silverman GA, Fishman MC, Zon LI. 1999. Zebrafish YAC, BAC, and PAC genomic libraries. Methods Cell Biol 60:235-258.
4. Amemiya CT, Zon LI. 1999. Generation of a zebrafish P1 artificial chromosome library. Genomics 58:211-213.
5. Ammermuller J, Kolb H. 1995. The organization of the turtle inner retina. I. ON- and OFF-center pathways. J Comp Neurol 358:1-34.
6. Belluardo N, Mudo G, Trovato Salinaro A, Le Gurun S, Charollais A, Serre-Beinier V, Amato G, Haefliger JA, Meda P, Condorelli DF. 2000. Expression of Connexin36 in the adult and developing rat brain. Brain Res 865:121-138.
7. Belluardo N, Trovato Salinaro A, Mudo G, Hurd YL, Condorelli DF. 1999. Structure, chromosomal localization, and brain expression of human Cx36 gene. J Neurosci 57:740-752.
8. Bruzzone R, White TW, Goodenough DA. 1996a. The cellular internet: on-line with connexins. Bioessays 18:709-718.
9. Bruzzone R, White TW, Paul DL. 1996b. Connections with connexins: the molecular basis of direct intercellular signaling. Eur J Biochem 238:1-27.
10. Cason N, White TW, Cheng S, Goodenough DA, Valdimarsson G. 2001. Molecular cloning, expression analysis, and functional characterization of connexin44.1: A zebrafish lens gap junction protein. Dev Dyn 221:238-247.
11. Condorelli DF, Belluardo N, Trovato-Salinaro A, Mudo G. 2000. Expression of Cx36 in mammalian neurons. Brain Res Brain Res Rev 32:72-85.
12. Condorelli DF, Parenti R, Spinella F, Trovato Salinaro A, Belluardo N, Cardile V, Cicirata F. 1998. Cloning of a new gap junction gene (Cx36) highly expressed in mammalian brain neurons. Eur J Neurosci 10:1202-1208.
13. Connaughton VP, Nelson R. 2000. Axonal stratification patterns and glutamate-gated conductance mechanisms in zebrafish retinal bipolar cells. J Physiol 524 Pt 1:135-146.
14. Deans MR, Gibson JR, Sellitto C, Connors BW, Paul DL. 2001. Synchronous activity of inhibitory networks in neocortex requires electrical synapses containing connexin36. Neuron 31:477-485.
15. Deans MR, Volgyi B, Goodenough DA, Bloomfield SA, Paul DL. 2002. Connexin36 is essential for transmission of rod-mediated visual signals in the mammalian retina. Neuron 36:703-712.
16. Dermietzel R, Kremer M, Paputsoglu G, Stang A, Skerrett IM, Gomes D, Srinivas M, Janssen-Bienhold U, Weiler R, Nicholson BJ, Bruzzone R, Spray DC. 2000. Molecular and functional diversity of neural connexins in the retina. J Neurosci 20:8331-8343.
17. Donaldson P, Eckert R, Green C, Kistler J. 1997. Gap junction channels: new roles in disease. Histol Histopathol 12:219-231.
18. Essner JJ, Laing JG, Beyer EC, Johnson RG, Hackett PB. 1996. Expression of zebrafish connexin43.4 in the notochord and tail bud of wild-type and mutant no tail embryos. Dev Biol 177:449-462.
19. Feigenspan A, Teubner B, Willecke K, Weiler R. 2001. Expression of neuronal connexin36 in AII amacrine cells of the mammalian retina. J Neurosci 21:230-239.
20. Güldenagel M, Ammermuller J, Feigenspan A, Teubner B, Degen J, Söhl G, Willecke K, Weiler R. 2001. Visual transmission deficits in mice with targeted disruption of the gap junction gene connexin36. J Neurosci 21:6036-6044.
21. Güldenagel M, Söhl G, Plum A, Traub O, Teubner B, Weiler R, Willecke K. 2000. Expression patterns of connexin genes in mouse retina. J Comp Neurol 425:193-201.
22. Gulisano M, Parenti R, Spinella F, Cicirata F. 2000. Cx36 is dynamically expressed during early development of mouse brain and nervous system. Neuroreport 11:3823-3828.
23. Kelsell DP, Dunlop J, Hodgins MB. 2001. Human diseases: clues to cracking the connexin code? Trends Cell Biol 11:2-6.
24. Krutovskikh V, Yamasaki H. 2000. Connexin gene mutations in human genetic diseases. Mutat Res 462:197-207.
25. Malicki J. 1999. Development of the retina. Methods Cell Biol 59:273-299.
26. Meier C, Petrasch-Parwez E, Habbes HW, Teubner B, Güldenagel M, Degen J, Söhl G, Willecke K, Dermietzel R. 2002. Immunohistochemical detection of the neuronal connexin36 in the mouse central nervous system in comparison to connexin36-deficient tissues. Histochem Cell Biol 117:461-471.
27. Mills SL, O'Brien JJ, Li W, O'Brien J, Massey SC. 2001. Rod pathways in the mammalian retina use connexin 36. J Comp Neurol 436:336-350.
28. Nelson K, Famiglietti EV Jr, Kolb H. 1978. Intracellular staining reveals different levels of stratification for on- and off-center ganglion cells in cat retina. J Neurophysiol 41:472-483.
29. O'Brien J, Al-Ubaidi MR, Ripps H. 1996. Connexin 35: a gap-junctional protein expressed preferentially in skate retina. Mol Biol Cell 7:233-243.
30. O'Brien J, Bruzzone R, White TW, Al-Ubaidi MR, Ripps H. 1998. Cloning and expression of two related connexins from the perch retina define a subgroup of the connexin family. J Neurosci 18:7625-7637.
31. Page RD. 1996. TreeView: an application to display phylogenetic trees on personal computers. Comput Appl Biosci 12:357-358.
32. Pareda A, O'Brien J, Nagy JI, Bukauskas FF, Davidson KG, Yasumura T, Rash JE. 2003. Connexin35 mediates electrical transmission at mixed synapses on Mauthner cells. J Neurosci (in press).
33. Parenti R, Gulisano M, Zappala' A, Cicirata F. 2000. Expression of connexin36 mRNA in adult rodent brain. NeuroReport 11:1497-1502.
34. Prime G, Horn G, Sutor B. 2000. Time-related changes in connexin mRNA abundance in the rat neocortex during postnatal development. Brain Res Dev Brain Res 119:111-125.
35. Rash JE, Staines WA, Yasumura T, Patel D, Furman CS, Stelmack GL, Nagy JI. 2000. Immunogold evidence that neuronal gap junctions in adult rat brain and spinal cord contain connexin-36 but not connexin-32 or connexin-43. Proc Natl Acad Sci USA 97:7573-7578.
36. Rozental R, Srinivas M, Gokhan S, Urban M, Dermietzel R, Kessler JA, Spray DC, Mehler MF. 2000. Temporal expression of neuronal connexins during hippocampal ontogeny. Brain Res Brain Res Rev 32:57-71.
37. Sambrook J, Fritsch EF, Maniatis T. 1989. Molecular cloning: a laboratory manual. New York: Cold Spring Harbor Laboratory Press.
38. Söhl G, Degen J, Teubner B, Willecke K. 1998. The murine gap junction gene connexin36 is highly expressed in mouse retina and regulated during brain development. FEBS Letters 428:27-31.
39. Spray DC, Harris AL, Bennett MV. 1981. Equilibrium properties of a voltage-dependent junctional conductance. J Gen Physiol 77:77-93.
40. Srinivas M, Rozental R, Kojima T, Dermietzel R, Mehler M, Condorelli DF, Kessler JA, Spray DC. 1999. Functional properties of channels formed by the neuronal gap junction protein connexin 36. J Neurosci 19:9848-9855.
41. Teubner B, Degen J, Söhl G, Güldenagel M, Bukauskas FF, Trexler EB, Verselis VK, De Zeeuw CI, Lee CG, Kozak CA, Petrasch-Parwez E, Dermietzel R, Willecke K. 2000. Functional expression of the murine connexin 36 gene coding for a neuron-specific gap junctional protein. J Membr Biol 176:249-262.
42. Thompson JD, Gibson TJ, Plewniak F, Jeanmougin F, Higgins DG. 1997. The CLUSTAL_X windows interface: flexible strategies for multiple sequence alignment aided by quality analysis tools. Nucleic Acids Res 25:4876-4882.
43. Turner DL, Weintraub H. 1994. Expression of achaete-scute homolog 3 in Xenopus embryos converts ectodermal cells to a neural fate. Genes Dev 8:1434-1447.
44. Weiler R, Pottek M, He S, Vaney DI. 2000. Modulation of coupling between retinal horizontal cells by retinoic acid and endogenous dopamine. Brain Res Brain Res Rev 32:121-129.
45. Westerfield M. 1995. The zebrafish book. Eugene, OR: University of Oregon Press.
46. White TW, Bruzzone R, Paul DL. 1995. The connexin family of intercellular channel forming proteins. Kidney Int 48:1148-1157.
47. White TW, Deans MR, O'Brien J, Al-Ubaidi MR, Goodenough DA, Ripps H, Bruzzone R. 1999. Functional characteristics of skate connexin35, a member of the gamma subfamily of connexins expressed in the vertebrate retina. Eur J Neurosci 11:1883-1890.
48. White TW, Paul DL. 1999. Genetic disease and gene knockouts reveal diverse connexin functions. Ann Rev Physiol 61:283-310.
49. Willecke K, Eiberger J, Degen J, Eckardt D, Romualdi A, Güldenagel M, Deutsch U, Söhl G. 2002. Structural and functional diversity of connexin genes in the mouse and human genome. Biol Chem 383:725-737.
50. Wullimann MF, Rupp B, Reichert H. 1996. Neuroanatomy of the zebrafish brain. Basel: Birkhäuser Verlag. 144 p.
51. Zoidl G, Meier C, Petrasch-Parwez E, Zoidl C, Habbes HW, Kremer M, Srinivas M, Spray DC, Dermietzel R. 2002. Evidence for a role of the N-terminal domain in subcellular localization of the neuronal connexin36 (Cx36). J Neurosci Res 69:448-465.