Polyomaviruses and cancer - Interplay between viral proteins and signal transduction pathways

Journal of Experimental and Clinical Cancer Research

Volumn 23, Issue 3, 2004, Pages 373-383

  Wang, J Ying ^a   Del Valle, L ^a   Peruzzi, F ^a   Trojanek, J ^a   Giordano, A ^b   Khalili, K ^a   Reiss, Krzystof ^a  

^a TEMPLE UNIVERSITY   (United States)

^b Temple University   (United States)

Author keywords

Brain tumors; IGF IR; Polyomaviruses; T antigens; Wnt pathway

Indexed keywords

CELL PROTEIN; REGULATOR PROTEIN; VIRUS PROTEIN; VIRUS T ANTIGEN;

ANIMAL CELL; BK VIRUS; CARCINOGENESIS; CELL CYCLE; DNA REPAIR; GENE EXPRESSION; HUMAN; JC VIRUS; LYMPHOTROPIC PAPOVIRUS; MALIGNANT TRANSFORMATION; MOUSE; NONHUMAN; PHENOTYPE; POLYOMA VIRUS; PRIORITY JOURNAL; PROTEIN PROTEIN INTERACTION; REGULATORY MECHANISM; REVIEW; SIGNAL TRANSDUCTION; SIMIAN VIRUS 40; VIRUS GENOME; VIRUS INFECTION;

ANIMALS; ANTIGENS, VIRAL, TUMOR; BINDING SITES; BRAIN NEOPLASMS; CELL CYCLE; CYTOPLASM; DNA REPAIR; GENE EXPRESSION REGULATION; GENOME, VIRAL; HUMANS; INTERCELLULAR SIGNALING PEPTIDES AND PROTEINS; MICE; MICE, NUDE; MODELS, BIOLOGICAL; NEOPLASM TRANSPLANTATION; POLYOMAVIRUS; PROTEIN BINDING; PROTEIN STRUCTURE, TERTIARY; RECEPTOR, IGF TYPE 1; RETINOBLASTOMA PROTEIN; SIGNAL TRANSDUCTION; TUMOR SUPPRESSOR PROTEIN P53; WNT PROTEINS;

EID: 8544237772     PISSN: 03929078     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Review

References (65)

1. Cole C.N.: Polyomavirinae: The viruses and their replication. In: P. M. Knipe (ed.), Fundamental Virology, 3 edition, pp. 917-945. Philadelphia: Lippincott-Raven Publishers, 1996.
2. Safak M.., Barrucco R., Darbinyan A., Okada Y., Nagashima K., and Khalili K.: Interaction of JC virus agno protein with T antigen modulates transcription and replication of the viral genome in glial cells. J. Virol. 75: 1476-1486, 2001.
3. Imperiale M.J.: The human polyomaviruses, BKV and JCV: molecular pathogenesis of acute disease and potential role in cancer. Virology 267: 1-7, 2000.
4. Imperiale M.J.: The Human Polyoviruses: an Overview: Wiley-Liss, 2001.
5. Rollison D.E. and Shah K.V.: The epidemiology of SV40 infection due to contaminated polio vaccines: relation of the virus to human cancer: Wiley-Liss Inc, 2001.
6. Arrington A.S. and Butel J.S.: SV40 and Human Tumors: Wiley-Liss Inc., 2001.
7. Gardner S.D., Field A.M., Coleman D.V., and Hulme B.: New human papovavirus (B.K.) isolated from urine after renal transplantation. Lancet 1: 1253-1257, 1971.
8. Padgett B.L., Walker D.L., ZuRhein G.M., Eckroade R.J., and Dessel B.H.: Cultivation of papova-like virus from human brain with progressive multifocal leucoencephalopathy. Lancet 1: 1257-1260, 1971.
9. Budka H. and Shah K.V.: Papovavirus antigens in paraffin sections of PML brains. Prog. Clin. Biol. Res. 105: 299-309, 1983.
10. Berger J.R. and Concha M.: Progressive multifocal leukoencephalopathy: the evolution of a disease once considered rare. J. Neurovirol. 1: 5-18, 1995.
11. Khalili K. and Stoner G.I.: Human Polyomaviruses:milecular and clinical perspectives: Wiley-Liss, Inc. 2001.
12. Soriano F., Shelburne C.E., and Gokcen M.: Simian virus 40 in a human cancer. Nature 249: 421-424, 1974.
13. Tognon M., Casalone R., Martini F., De Mattei M., Granata P., Minelli E., Arcuri C., Collini P., and Bocchini V.: Large T antigen coding sequences of two DNA tumor viruses, BK and SV40, and nonrandom chromosome changes in two glioblastoma cell lines. Cancer Genet. Cytogenet. 90: 17-23, 1996.
14. Monini P., Rotola A., de Lellis L., Corallini A., Secchiero P., Albini A., Benelli R., Parravicini C., Barbanti-Brodano G., and Cassai E.: Latent BK virus infection and Kaposi's sarcoma pathogenesis. Int. J. Cancer 66: 717-722, 1996.
15. Monini P., Rotola A., Di Luca D., De Lellis L., Chiari E., Corallini A., and Cassai E.: DNA rearrangements impairing BK virus productive infection in urinary tract tumors. Virology 214: 273-279, 1995.
16. De Mattei M., Martini F., Corallini A., Gerosa M., Scotlandi K., Carinci P., Barbanti-Brodano G., and Tognon M.: High incidence of BK virus large-T-antigen-coding sequences in normal human tissues and tumors of different histotypes. Int. J. Cancer 61: 756-760, 1995.
17. Del Valle L., Gordon J., Ferrante P., and Khalili K.: JC virus in experimental and clinical brain tumors. In: Human Polyoviruses Molecular and Clinical Perspectives, 1 edition, pp. 409-430. New York: Wiley-Liss, Inc., 2001.
18. Enam S., Del Valle L., Lara C., Gan D.D., Ortiz-Hidalgo C., Palazzo J.P., and Khalili K.: Association of human polyomavirus JCV with colon cancer: evidence for interaction of viral T-antigen and beta-catenin. Cancer Res. 62: 7093-7101, 2002.
19. Sullivan C.S., Tremblay J.D., Fewell S.W., Lewis J.A., Brodsky J.L., and Pipas J.M.: Species-specific elements in the large T-antigen J domain are required for cellular transformation and DNA replication by simian virus 40. Mol. Cell Biol. 20: 5749-5757, 2000.
20. Kang S. and Folk W.R.: Lymphotropic papovavirus transforms hamster cells without altering the amount or stability of p53. Virology 191: 754-764, 1992.
21. Haggerty S., Walker D.L., and Frisque R.J.: JC virus-simian virus 40 genomes containing heterologous regulatory signals and chimeric early regions: identification of regions restricting transformation by JC virus. J. Virol. 63: 2180-2190, 1989.
22. Walker D.L., Padgett B.L., ZuRhein G.M., Albert A.E., and Marsh R.F.: Human papovavirus (JC): induction of brain tumors in hamsters. Science 181: 674-676, 1973.
23. Zu Rhein G.M. and Varakis J.: Perinatal induction of medulloblastomas in Syrian golden hamsterbe a human polyomavirus JC. Natl. Cancer Inst. Monogr. 51: 205-208, 1979.
24. Ohsumi S., Motoi M., and Ogawa K.: Induction of undifferentiated tumors by JC virus in the cerebrum of rats. Acta Pathol. Jpn. 36: 815-825, 1986.
25. London W.T., Houff S.A., McKeever P.E., Wallen W.C., Sever J.L., Padgett B.L., and Walker D.L.: Viral-induced astrocytomas in squirrel monkeys. Prog. Clin. Biol. Res. 105: 227-237, 1983.
26. Small, J. A., Scangos, G. A., Cork, L., Jay, G., and Khoury, G. The early region of human papovavirus JC induces dysmyelination in transgenic mice. Cell, 46: 13-18., 1986.
27. Krynska B., Otte J., Franks R., Khalili K., and Croul S.: Human ubiquitous JCV(CY) T-antigen gene induces brain tumors in experimental animals. Oncogene 18: 39-46, 1999.
28. Krynska B., Del Valle L., Gordon J., Otte J., Croul S., and Khalili K.: Identification of a novel p53 mutation in JCV-induced mouse medulloblastoma. Virology 274: 65-74, 2000.
29. Wang J.Y., Del Valle L., Gordon J., Rubini M., Romano G., Croul S., Peruzzi F., Khalili K., and Reiss K.: Activation of the IGF-IR system contributes to malignant growth of human and mouse medulloblastomas. Oncogene 20: 3857-3868, 2001.
30. Pipas J.M.: Common and unique features of T antigens encoded by the polyomavirus group. J. Virol. 66: 3979-3985, 1992.
31. Bollag B., Chuke W.F., and Frisque R.J.: Hybrid genomes of the polyomaviruses JC virus, BK virus, and simian virus 40: identification of sequences important for efficient transformation. J. Virol. 63: 863-872, 1989.
32. Gallia G.L., Safak M., and Khalili K.: Interaction of the single-stranded DNA-binding protein Puralpha with the human polyomavirus JC virus early protein T-antigen. J. Biol. Chem. 273: 32662-32669, 1998.
33. Safak M., Gallia G.L., Ansari S.A., and Khalili K.: Physical and functional interaction between the Y-box binding protein YB-1 and human polyomavirus JC virus large T antigen. J. Virol. 73: 10146-10157, 1999.
34. Lassak A., Del Valle L., Peruzzi F., Wang J.Y., Enam S., Croul S., Khalili K., and Reiss K.: Insulin Receptor Substrate 1 Translocation to the Nucleus by the Human JC Virus T-antigen. J. Biol. Chem. 277: 17231-17238, 2002.
35. Baserga R.: The 1GF-I receptor in cancer research. Exp. Cell Res. 253: 1-6, 1999.
36. Kleihues P., Louis D.N., Scheithauer B.W., Rorke L.B., Reifenberger G., Burger P.C., and Cavenee W.K.: The WHO classification of tumors of the nervous system. J. Neuropathol. Exp. Neurol. 61: 215-225; discussion 226-219, 2002.
37. Reiss K.: Insulin-like growth factor-I receptor - a potential therapeutic target in medulloblastomas. Expert Opin. Ther. Targets 6: 539-544, 2002.
38. Del Valle L., Enam S., Lassak A., Wang J.Y., Croul S., Khalili K., and Reiss K.: Insulin-like Growth Factor I Receptor Activity in Human Medulloblastomas. Clin. Cancer Res. 8: 1822-1830, 2002.
39. Del Valle L., Wang J.Y., Lassak A., Peruzzi F., Croul S., Khalili K., and Reiss K.: Insulin-like growth factor I receptor signaling system in JC virus T antigen-induced primitive neuroectodermal tumors-medulloblastomas. J. Neurovirol. 8 Suppl 2: 138-147, 2002.
40. Patti R., Reddy C.D., Geoerger B., Grotzer M.A., Raghunath M., Sutton L.N., and Phillips P.C.: Autocrine secreted insulin-like growth factor-I stimulates MAP kinase- dependent mitogenic effects in human primitive neuroectodermal tumor/medulloblastoma. Int. J. Oncol. 16: 577-584, 2000.
41. Krynska B., Del Valle L., Croul S., Gordon J., Katsetos C.D., Carbone M., Giordano A., and Khalili K.: Detection of human neurotropic JC virus DNA sequence and expression of the viral oncogenic protein in pediatric medulloblastomas. Proc. Natl. Acad. Sci. U.S.A. 96: 11519-11524, 1999.
42. Del Valle L., Gordon J., Enam S., Delbue S., Croul S., Abraham S., Radhakrishnan S., Assimakopoulou M., Katsetos C.D., and Khalili K.: Expression of human neurotropic polyomavirus JCV late gene product agnoprotein in human medulloblastoma. J. Natl. Cancer Inst. 94: 267-273, 2002.
43. Reiss K., Valentinis B., Tu X., Xu S.Q., and Baserga R.: Molecular markers of IGF-I-mediated mitogenesis. Exp. Cell Res. 242: 361-372, 1998.
44. Reiss K., Cheng W., Kajstura J., Sonnenblick E.H., Meggs L.G., and Anversa P.: Fibroblast proliferation during myocardial development in rats is regulated by IGF-1 receptors. Am. J. Physiol. 269: H943-951, 1995.
45. Reiss K., Tu X., Romano G., Peruzzi F., Wang J.Y., and Baserga R.: Intracellular association of a mutant insulin-like growth factor receptor with endogenous receptors. Clin. Cancer Res. 7: 2134-2144, 2001.
46. Reiss K., D'Ambrosio C., Tu X., Tu C., and Baserga R.: Inhibition of tumor growth by a dominant negative mutant of the insulin- like growth factor I receptor with a bystander effect. Clin. Cancer Res. 4: 2647-2655, 1998.
47. Tu X., Batta P., Innocent N., Prisco M., Casaburi I., Belletti B., and Baserga R.: Nuclear translocation of insulin receptor substrate-1 by oncogenes and Igf-I. Effect on ribosomal RNA synthesis. J. Biol. Chem. 277: 44357-44365, 2002.
48. Zurawel R.H., Chiappa S.A., Allen C., and Raffel C.: Sporadic medulloblastomas contain oncogenic beta-catenin mutations. Cancer Res. 58: 896-899, 1998.
49. Yokota N., Nishizawa S., Ohta S., Date H., Sugimura H., Namba H., and Maekawa M.: Role of Wnt pathway in medulloblastoma oncogenesis. Int. J. Cancer 101: 198-201, 2002.
50. Gan D.D., Reiss K., Carrill T., Del Valle L., Croul S., Giordano A., Fishman P., and Khalili K.: Involvement of Wnt signaling pathway in murine medulloblastoma induced by human neurotropic JC virus. Oncogene 20: 4864-4870, 2001.
51. Prins C. and Frisque R.J.: JC virus T' proteins encoded by alternatively spliced early mRNAs enhance T antigen-mediated viral DNA replication in human cells. J. Neurovirol. 7: 250-264, 2001.
52. Bollag B., Prins C., Snyder E.L., and Frisque R.J.: Purified JC virus T and T' proteins differentially interact with the retinoblastoma family of tumor suppressor proteins. Virology 274: 165-178, 2000.
53. Rundell K. and Parakati R.: The role of the SV40 ST antigen in cell growth promotion and transformation. Semin. Cancer Biol. 11: 5-13, 2001.
54. Sontag E., Fedorov S., Kamibayashi C., Robbins D., Cobb M., and Mumby M.: The interaction of SV40 small tumor antigen with protein phosphatase 2A stimulates the map kinase pathway and induces cell proliferation. Cell 75: 887-897, 1993.
55. Frost J.A., Alberts A.S., Soṅtag E., Guan K., Mumby M.C., and Feramisco J.R.: Simian virus 40 small t antigen cooperates with mitogen-activated kinases to stimulate AP-1 activity. Mol. Cell Biol. 14: 6244-6252, 1994.
56. Wheat W.H., Roesler W.J., and Klemm D.J.: Simian virus 40 small tumor antigen inhibits dephosphorylation of protein kinase A-phosphorylated CREB and regulates CREB transcriptional stimulation. Mol. Cell Biol. 14: 5881-5890, 1994.
57. Sheaff R.J., Groudine M., Gordon M., Roberts J.M., and Clurman B.E.: Cyclin E-CDK2 is a regulator of p27Kip1. Genes Dev. 11: 1464-1478, 1997.
58. Zerfass-Thome K., Schulze A., Zwerschke W., Vogt B., Helin K., Bartek J., Henglein B., and Jansen-Durr P.: p27KIP1 blocks cyclin E-dependent transactivation of cyclin A gene expression. Mol. Cell Biol. 17: 407-415, 1997.
59. Darbinyan A., Darbinian N., Safak M., Radhakrishnan S., Giordano A., and Khalili K.: Evidence for dysregulation of cell cycle by human polyomavirus, JCV, late auxiliary protein. Oncogene 21: 5574-5581, 2002.
60. Del Valle L., Enam S., Lara C., Ortiz-Hidalgo C., Katsetos C.D., and Khalili K.: Detection of JC Polyomavirus DNA Sequences and Cellular Localization of T-Antigen and Agnoprotein in Oligodendrogliomas. Clin. Cancer Res. 8: 3332-3340, 2002.
61. Richardson E.P.: Progressive multifocal leukoencephalopathy. N. Engl. J. Med. 265: 815-823, 1961.
62. Sima A.A., Finkelstein S.D., and McLachlan D.R.: Multiple malignant astrocytomas in a patient with spontaneous progressive multifocal leukoencephalopathy. Ann. Neurol. 14: 183-188, 1983.
63. Castaigne P., Rondot P., Escourolle R., Ribadeau dumas J.L., Cathala F., and Hauw J.J.: [Progressive multifocal leukoencephalopathy and multiple gliomas]. Rev. Neurol. (Paris) 130: 379-392, 1974.
64. Shintaku M., Matsumoto R., Sawa H., and Nagashima K.: Infection with JC virus and possible dysplastic ganglion-like transformation of the cerebral cortical neurons in a case of progressive multifocal leukoencephalopathy. J. Neuropathol. Exp. Neurol. 59: 921-929, 2000.
65. Del Valle L., Gordon J., Assimakopoulou M., Enam S., Geddes J.F., Varakis J.N., Katsetos C.D., Croul S., and Khalili K.: Detection of JC virus DNA sequences and expression of the viral regulatory protein T-antigen in tumors of the central nervous system. Cancer Res. 61: 4287-4293, 2001.