Involvement of Wnt signaling pathway in murine medulloblastoma induced by human neurotropic JC virus

Oncogene

Volumn 20, Issue 35, 2001, Pages 4864-4870

  Gan, Dai Di ^a   Reiss, Krzysztof ^a   Carrill, Timothy ^a   Del Valle, Luis ^a   Croul, Sidney ^a   Giordano, Antonio ^b   Fishman, Pnina ^c   Khalili, Kamel ^a  

^a Temple University   (United States)

^b THOMAS JEFFERSON UNIVERSITY   (United States)

^c RABIN MEDICAL CENTER   (Israel)

Author keywords

Human polyomavirus; JCV; Medulloblastoma; T antigen; Wnt pathway

Indexed keywords

BETA CATENIN; CELL PROTEIN; LYMPHOID ENHANCER FACTOR 1; RNA; VIRUS T ANTIGEN; WNT PROTEIN;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTIGEN EXPRESSION; ARTICLE; CARCINOGENICITY; CELL CLONE; CELL LEVEL; CONTROLLED STUDY; DNA BINDING; GENETIC TRANSFECTION; GENOME; IMMUNOHISTOCHEMISTRY; JC VIRUS; MEDULLOBLASTOMA; MOUSE; NONHUMAN; NORTHERN BLOTTING; ONCOGENE C MYC; PRIORITY JOURNAL; PROTEIN EXPRESSION; SIGNAL TRANSDUCTION; TRANSGENIC MOUSE; TUMOR CELL; WESTERN BLOTTING;

ANIMALS; ANTIGENS, VIRAL, TUMOR; BETA CATENIN; BINDING SITES; CEREBELLAR NEOPLASMS; CYTOSKELETAL PROTEINS; DNA-BINDING PROTEINS; GENES, MYC; HUMANS; JC VIRUS; LYMPHOID ENHANCER-BINDING FACTOR 1; MEDULLOBLASTOMA; MICE; PROTO-ONCOGENE PROTEINS; TRANS-ACTIVATORS; TRANSCRIPTION FACTORS; WNT PROTEINS; ZEBRAFISH PROTEINS;

ANIMALIA; JC VIRUS; MURINAE; MUS MUSCULUS; POLYOMAVIRUS; RNA VIRUSES;

EID: 0035833343     PISSN: 09509232     EISSN: None     Source Type: Journal    
DOI: 10.1038/sj.onc.1204670     Document Type: Article

References (29)

1. Cadherin-catenin complex: Protein interactions and their implications for cadherin function
2. Functional interaction of b-catenin with the transcription factor LEF-1
3. Progressive multifocal leukoencephalopathy: The evolution of a disease once considered rare
4. Wnt signaling: A common theme in animal development
5. Tumor suppressor genes and medulloblastoma
6. Control of neural crest cell fate by the Wnt signaling pathway
7. Nuclear localization and mutation of b-catenine in medulloblastoma
8. Medulloblastoma in childhood: An epidemiological study
9. Formation of undifferentiated mesenteric tumors in transgenic mice expressing human neurotropic polyomavirus early protein
10. Tumor pathogenesis of human neurotropic JC virus in the CNS
11. Pituitary neoplasia induced by expression of human neurotropic polyomavirus, JCV, early genome in transgenic mice
12. Inducible pRb2/p130 expression and growth-suppressive mechanisms: Evidence of a pRb2/p130, p27kip1, and cyclin E negative feedback regulatory loop
13. E-cadherin and APC complete for the interaction with beta-catenin and the cytoskeleton
14. Genetic and biochemical dissection of protein linkages in the cadherin-catenin complex
15. Role of cell cycle regulators in tumor formation in transgenic mice expressing the human neurotropic virus, JCV, early protein
16. Human ubiquitous JCVCY T-antigen gene induces brain tumors in experimental animals
17. Identification of a novel p53 mutation in JCV-induced mouse medulloblastoma
18. Pathogenesis and molecular biology of progressive multifocal leukoencephalopathy, the JCV virus-induced demyelinating disease of the human brain
19. Induction of medulloblastomas in p53-null mutant mice by somatic inactivation of Rb in the external granular layer cells of the cerebellum
20. Twenty years of p53 research: Structural and functional aspects of the p53 protein
21. 2+ pathways
22. WNTs modulate cell fate and behavior during vertebrate development
23. β-Catenin signaling and cancer
24. Retinoblastoma protein family in cell cycle and cancer: A review
25. The early region of human papovavirus JC induces dysmyelination in transgenic mice
26. Early regions of JC virus and BK virus induce distinct and tissue-specific tumors in transgenic mice
27. Prevalence rate and age of acquisition of antibodies against JC virus and Bk virus in human sera
28. The epidemiology of human papovaviruses