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Volumn , Issue , 2008, Pages 514-528

Clinical trials: Acute and chronic pain

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EID: 85136739214     PISSN: None     EISSN: None     Source Type: Book    
DOI: 10.1201/b13562-42     Document Type: Chapter
Times cited : (8)

References (66)
  • 1
    • 0014115513 scopus 로고
    • Explanatory and pragmatic attitudes in therapeutical trials
    • Schwartz D, Lellouch J. Explanatory and pragmatic attitudes in therapeutical trials. Journal of Chronic Diseases. 1967; 20: 637-48.
    • (1967) Journal of Chronic Diseases , vol.20 , pp. 637-648
    • Schwartz, D.1    Lellouch, J.2
  • 2
    • 85047692188 scopus 로고
    • Empirical evidence of bias. Dimensions of methodological quality associated with estimates of treatment effects in controlled trials
    • Schulz KF, Chalmers I, Hayes RJ, Altman DG. Empirical evidence of bias. Dimensions of methodological quality associated with estimates of treatment effects in controlled trials. Journal of the American Medical Association. 1995; 273: 408-12.
    • (1995) Journal of the American Medical Association , vol.273 , pp. 408-412
    • Schulz, K.F.1    Chalmers, I.2    Hayes, R.J.3    Altman, D.G.4
  • 4
    • 85136643544 scopus 로고    scopus 로고
    • The design of clinical trials of pain treatment
    • Max MB, Lynn J. editors, Last updated October 2003, cited February. Available from
    • Max MB. The design of clinical trials of pain treatment. In:Max MB, Lynn J. editors. Symptom research. Methods and opportunities. An interactive textbook. Last updated October 2003, cited February 2008. Available from: http:// symptomresearch.nih.gov/chapter_1/index.htm.
    • (2008) Symptom research. Methods and opportunities. An interactive textbook
    • Max, M.B.1
  • 5
    • 0032569383 scopus 로고    scopus 로고
    • When placebo controlled trials are essential and equivalence trials are inadequate
    • Tramer MR, Reynolds DJ, Moore RA, McQuay HJ. When placebo controlled trials are essential and equivalence trials are inadequate. British Medical Journal. 1998; 317:875-80.
    • (1998) British Medical Journal , vol.317 , pp. 875-880
    • Tramer, M.R.1    Reynolds, D.J.2    Moore, R.A.3    McQuay, H.J.4
  • 6
    • 0034123634 scopus 로고    scopus 로고
    • Current issues in clinical trial design: Superiority versus equivalency studies
    • Landow L. Current issues in clinical trial design: superiority versus equivalency studies. Anesthesiology. 2000; 92:1814-20.
    • (2000) Anesthesiology , vol.92 , pp. 1814-1820
    • Landow, L.1
  • 7
    • 85136616747 scopus 로고    scopus 로고
    • Comparison of tramadol with morphine for post-operative pain following abdominal surgery
    • Stubhaug A. Comparison of tramadol with morphine for post-operative pain following abdominal surgery. European Journal of Anaesthesiology. 1996; 13:416-17.
    • (1996) European Journal of Anaesthesiology , vol.13 , pp. 416-417
    • Stubhaug, A.1
  • 8
    • 0014324839 scopus 로고
    • A clinical comparison of the effects of oral and intramuscular administration of analgesics: Pentazocine and phenazocine
    • Beaver WT, Wallenstein SL, Houde RW, Rogers A. A clinical comparison of the effects of oral and intramuscular administration of analgesics: pentazocine and phenazocine. Clinical Pharmacology and Therapeutics. 1968; 9: 582-97.
    • (1968) Clinical Pharmacology and Therapeutics , vol.9 , pp. 582-597
    • Beaver, W.T.1    Wallenstein, S.L.2    Houde, R.W.3    Rogers, A.4
  • 9
    • 0024509712 scopus 로고
    • Variables of patient-controlled analgesia. 1. Bolus size
    • Owen H, Plummer JL, Armstrong I et al. Variables of patient-controlled analgesia. 1. Bolus size. Anaesthesia. 1989; 1: 7-10.
    • (1989) Anaesthesia , vol.1 , pp. 7-10
    • Owen, H.1    Plummer, J.L.2    Armstrong, I.3
  • 10
    • 0028132221 scopus 로고
    • Divergent traditions in analgesic clinical trials
    • Max MB. Divergent traditions in analgesic clinical trials. Clinical Pharmacology and Therapeutics. 1994; 56:237-41.
    • (1994) Clinical Pharmacology and Therapeutics , vol.56 , pp. 237-241
    • Max, M.B.1
  • 11
    • 0345019847 scopus 로고    scopus 로고
    • Efficient designs for studying synergistic drug combinations
    • Tallarida RJ, Stone DJ, Raffa RB. Efficient designs for studying synergistic drug combinations. Life Sciences. 1997; 61: 417-25.
    • (1997) Life Sciences , vol.61 , pp. 417-425
    • Tallarida, R.J.1    Stone, D.J.2    Raffa, R.B.3
  • 14
    • 9244231147 scopus 로고    scopus 로고
    • Gender is a confounding factor in pain trials: Women report more pain than men after arthroscopic surgery
    • Rosseland LA, Stubhaug A. Gender is a confounding factor in pain trials: Women report more pain than men after arthroscopic surgery. Pain. 2004; 112: 248-53.
    • (2004) Pain , vol.112 , pp. 248-253
    • Rosseland, L.A.1    Stubhaug, A.2
  • 16
    • 0034694856 scopus 로고    scopus 로고
    • World Medical Association Declaration of Helsinki: Ethical principles for medical research involving human
    • World Medical Association Declaration of Helsinki: ethical principles for medical research involving human. Journal of the American Medical Association. 2000; 284:3043-45.
    • (2000) Journal of the American Medical Association , vol.284 , pp. 3043-3045
  • 21
    • 0030608236 scopus 로고    scopus 로고
    • Randomised trials, human nature, and reporting guidelines
    • Schulz KF. Randomised trials, human nature, and reporting guidelines. Lancet. 1996; 348: 596-8.
    • (1996) Lancet , vol.348 , pp. 596-598
    • Schulz, K.F.1
  • 22
    • 34548595472 scopus 로고    scopus 로고
    • Impact of allocation concealment on conclusions drawn from metaanalyses of randomized trials
    • Pildal J, Hrobjartsson A, Jorgensen K et al. Impact of allocation concealment on conclusions drawn from metaanalyses of randomized trials. International Journal of Epidemiology. 2007; 36: 847-57.
    • (2007) International Journal of Epidemiology , vol.36 , pp. 847-857
    • Pildal, J.1    Hrobjartsson, A.2    Jorgensen, K.3
  • 23
    • 0035857966 scopus 로고    scopus 로고
    • The CONSORT statement:Revised recommendations for improving the quality of reports of parallel-group randomised trials
    • Moher D, Schulz KF, Altman DG. The CONSORT statement:revised recommendations for improving the quality of reports of parallel-group randomised trials. Lancet. 2001; 357: 1191-4.
    • (2001) Lancet , vol.357 , pp. 1191-1194
    • Moher, D.1    Schulz, K.F.2    Altman, D.G.3
  • 24
    • 0035901579 scopus 로고    scopus 로고
    • CONSORT GROUP (Consolidated Standards of Reporting Trials). The revised CONSORT statement for reporting randomized trials:Explanation and elaboration
    • Altman DG, Schulz KF, Moher D et al. CONSORT GROUP (Consolidated Standards of Reporting Trials). The revised CONSORT statement for reporting randomized trials:explanation and elaboration. Annals of Internal Medicine. 2001; 134: 663-94.
    • (2001) Annals of Internal Medicine , vol.134 , pp. 663-694
    • Altman, D.G.1    Schulz, K.F.2    Moher, D.3
  • 25
    • 0034930536 scopus 로고    scopus 로고
    • Mechanism-based pain diagnosis:Issues for analgesic drug development
    • Woolf CJ, Max MB. Mechanism-based pain diagnosis:issues for analgesic drug development. Anesthesiology. 2001; 95: 241-9.
    • (2001) Anesthesiology , vol.95 , pp. 241-249
    • Woolf, C.J.1    Max, M.B.2
  • 26
    • 0141738781 scopus 로고    scopus 로고
    • Controlledrelease oxycodone relieves neuropathic pain: A randomized controlled trial in painful diabetic neuropathy
    • Watson CP, Moulin D, Watt-Watson J et al. Controlledrelease oxycodone relieves neuropathic pain: a randomized controlled trial in painful diabetic neuropathy. Pain. 2003; 105: 71-78.
    • (2003) Pain , vol.105 , pp. 71-78
    • Watson, C.P.1    Moulin, D.2    Watt-Watson, J.3
  • 27
    • 34249780537 scopus 로고    scopus 로고
    • Morphine, nortriptyline and their combination vs. placebo in patients with chronic lumbar root pain
    • Khoromi S, Cui L, Nackers L, Max MB. Morphine, nortriptyline and their combination vs. placebo in patients with chronic lumbar root pain. Pain. 2007; 130:66-75.
    • (2007) Pain , vol.130 , pp. 66-75
    • Khoromi, S.1    Cui, L.2    Nackers, L.3    Max, M.B.4
  • 28
    • 0023928519 scopus 로고
    • Association of pain relief with drug side effects in postherpetic neuralgia: A single-dose study of clonidine, codeine, ibuprofen, and placebo
    • Max MB, Schafer SC, Culnane M et al. Association of pain relief with drug side effects in postherpetic neuralgia: a single-dose study of clonidine, codeine, ibuprofen, and placebo. Clinical Pharmacology and Therapeutics. 1988; 43: 363-71.
    • (1988) Clinical Pharmacology and Therapeutics , vol.43 , pp. 363-371
    • Max, M.B.1    Schafer, S.C.2    Culnane, M.3
  • 29
    • 8544270106 scopus 로고    scopus 로고
    • Methylprednisolone intravenously 1 day after surgery has sustained analgesic and opioid-sparing effectys
    • Romundstad L, Breivik H, Niemi G et al. Methylprednisolone intravenously 1 day after surgery has sustained analgesic and opioid-sparing effectys. Acta Anaesthesiologica Scandinavica. 2004; 48:1223-31.
    • (2004) Acta Anaesthesiologica Scandinavica , vol.48 , pp. 1223-1231
    • Romundstad, L.1    Breivik, H.2    Niemi, G.3
  • 30
    • 34547830379 scopus 로고    scopus 로고
    • Blinded trials taken to the test: An analysis of randomized clinical trials that report tests for the success of blinding
    • Hróbjartsson A, Forfang E, Haahr MT et al. Blinded trials taken to the test: an analysis of randomized clinical trials that report tests for the success of blinding. International Journal of Epidemiology. 2007; 36: 654-63.
    • (2007) International Journal of Epidemiology , vol.36 , pp. 654-663
    • Hróbjartsson, A.1    Forfang, E.2    Haahr, M.T.3
  • 31
    • 11144330148 scopus 로고    scopus 로고
    • A placebo-controlled randomized clinical trial of perioperative administration of gabapentin, rofecoxib and their combination for spontaneous and movement-evoked pain after abdominal hysterectomy
    • Gilron I, Orr E, Tu D et al. A placebo-controlled randomized clinical trial of perioperative administration of gabapentin, rofecoxib and their combination for spontaneous and movement-evoked pain after abdominal hysterectomy. Pain. 2005; 113: 191-200.
    • (2005) Pain , vol.113 , pp. 191-200
    • Gilron, I.1    Orr, E.2    Tu, D.3
  • 32
    • 0020510140 scopus 로고
    • Evaluation of current clinical trial methodology in analgesimetry based on experts’ opinions and analysis of several analgesic studies
    • Sriwatanakul K, Lasagna L, Cox C. Evaluation of current clinical trial methodology in analgesimetry based on experts’ opinions and analysis of several analgesic studies. Clinical Pharmacology and Therapeutics. 1983; 34:277-83.
    • (1983) Clinical Pharmacology and Therapeutics , vol.34 , pp. 277-283
    • Sriwatanakul, K.1    Lasagna, L.2    Cox, C.3
  • 34
    • 41749112010 scopus 로고    scopus 로고
    • Individual differences in pain sensitivity: Genetic and environmental contributions
    • Nielsen CS, Stubhaug A, Price DD et al. Individual differences in pain sensitivity: Genetic and environmental contributions. Pain. 2008; 136: 21-9.
    • (2008) Pain , vol.136 , pp. 21-29
    • Nielsen, C.S.1    Stubhaug, A.2    Price, D.D.3
  • 35
    • 0035691412 scopus 로고    scopus 로고
    • Designing pain research from the patients perspective: What trial end points are important to patients with chronic pain?
    • Casarett D, Karlawish J, Sankar P et al. Designing pain research from the patients perspective: what trial end points are important to patients with chronic pain? Pain Medicine. 2001; 2: 309-16.
    • (2001) Pain Medicine , vol.2 , pp. 309-316
    • Casarett, D.1    Karlawish, J.2    Sankar, P.3
  • 36
    • 19944381491 scopus 로고    scopus 로고
    • Core outcome measures for chronic pain clinical trials: IMMPACT recommendations
    • Dworkin RH, Turk DC, Farrar JT et al. Core outcome measures for chronic pain clinical trials: IMMPACT recommendations. Pain. 2005; 113: 9-19.
    • (2005) Pain , vol.113 , pp. 9-19
    • Dworkin, R.H.1    Turk, D.C.2    Farrar, J.T.3
  • 37
    • 0342514654 scopus 로고    scopus 로고
    • A comparison of pain rating scales by sampling from clinical trial data
    • Breivik EK, Bjornsson GA, Skovlund E. A comparison of pain rating scales by sampling from clinical trial data. Clinical Journal of Pain. 2000; 16: 22-8.
    • (2000) Clinical Journal of Pain , vol.16 , pp. 22-28
    • Breivik, E.K.1    Bjornsson, G.A.2    Skovlund, E.3
  • 38
    • 0023158554 scopus 로고
    • Sensory-affective relationships among different types of clinical and experimental pain
    • Price DD, Harkins SW, Baker C. Sensory-affective relationships among different types of clinical and experimental pain. Pain. 1987; 28: 297-307.
    • (1987) Pain , vol.28 , pp. 297-307
    • Price, D.D.1    Harkins, S.W.2    Baker, C.3
  • 39
    • 0023576853 scopus 로고
    • The short-form McGill Pain Questionnaire
    • Melzack R. The short-form McGill Pain Questionnaire. Pain. 1987; 30: 191-7.
    • (1987) Pain , vol.30 , pp. 191-197
    • Melzack, R.1
  • 40
    • 0030661767 scopus 로고    scopus 로고
    • Mapping of punctuate hyperalgesia surrounding a surgical incision demonstrates that ketamine is a powerful suppressor of central sensitization to pain following surgery
    • Stubhaug A, Breivik H, Eide PK et al. Mapping of punctuate hyperalgesia surrounding a surgical incision demonstrates that ketamine is a powerful suppressor of central sensitization to pain following surgery. Acta Anaesthesiologica Scandinavica. 1997; 41: 1124-32.
    • (1997) Acta Anaesthesiologica Scandinavica , vol.41 , pp. 1124-1132
    • Stubhaug, A.1    Breivik, H.2    Eide, P.K.3
  • 41
    • 0033830023 scopus 로고    scopus 로고
    • Effects of the AMPA/kainate antagonist LY293558 on spontaneous and evoked postoperative pain
    • Gilron I, Max MB, Lee G et al. Effects of the AMPA/kainate antagonist LY293558 on spontaneous and evoked postoperative pain. Clinical Pharmacology and Therapeutics. 2000; 68: 320-7.
    • (2000) Clinical Pharmacology and Therapeutics , vol.68 , pp. 320-327
    • Gilron, I.1    Max, M.B.2    Lee, G.3
  • 42
    • 0031787829 scopus 로고    scopus 로고
    • Effects of gabapentin on the different components of peripheral and central neuropathic pain syndromes: A pilot study
    • Attal N, Brasseur L, Parker F et al. Effects of gabapentin on the different components of peripheral and central neuropathic pain syndromes: a pilot study. European Neurology. 1998; 40: 191-200.
    • (1998) European Neurology , vol.40 , pp. 191-200
    • Attal, N.1    Brasseur, L.2    Parker, F.3
  • 43
    • 0034905273 scopus 로고    scopus 로고
    • Systemic adenosine infusion reduces the area of tactile allodynia in neuropathic pain following peripheral nerve injury: A multi-centre, placebo-controlled study
    • Sjolund KF, Belfrage M, Karlsten R et al. Systemic adenosine infusion reduces the area of tactile allodynia in neuropathic pain following peripheral nerve injury: a multi-centre, placebo-controlled study. European Journal of Pain. 2001; 5: 199-207.
    • (2001) European Journal of Pain , vol.5 , pp. 199-207
    • Sjolund, K.F.1    Belfrage, M.2    Karlsten, R.3
  • 44
    • 0037316640 scopus 로고    scopus 로고
    • Cold allodynia and hyperalgesia in neuropathic pain: The effect of N-methyl-D-aspartate (NMDA) receptor antagonist ketamine; a double blind, cross-over comparison with alfentanil and placebo
    • Jørum E, Warncke T, Stubhaug A. Cold allodynia and hyperalgesia in neuropathic pain: the effect of N-methyl-D-aspartate (NMDA) receptor antagonist ketamine; a double blind, cross-over comparison with alfentanil and placebo. Pain. 2003; 101: 229-35.
    • (2003) Pain , vol.101 , pp. 229-235
    • Jørum, E.1    Warncke, T.2    Stubhaug, A.3
  • 46
    • 0035841813 scopus 로고    scopus 로고
    • Statistics notes: Analysing controlled trials with baseline and follow up measurements
    • Vickers AJ, Altman DJ. Statistics notes: Analysing controlled trials with baseline and follow up measurements. British Medical Journal (Clinical research ed.). 2001; 323: 1123-4.
    • (2001) British Medical Journal (Clinical research ed.) , vol.323 , pp. 1123-1124
    • Vickers, A.J.1    Altman, D.J.2
  • 47
    • 0027241583 scopus 로고
    • Integrated assessment of pain scores and rescue morphine use during studies of analgesic efficacy
    • Silverman DG, O’Connor TZ, Brull SJ. Integrated assessment of pain scores and rescue morphine use during studies of analgesic efficacy. Anesthesia and Analgesia. 1993; 77: 168-70.
    • (1993) Anesthesia and Analgesia , vol.77 , pp. 168-170
    • Silverman, D.G.1    O’Connor, T.Z.2    Brull, S.J.3
  • 48
    • 31444454307 scopus 로고    scopus 로고
    • Methylprednisolone reduces pain, emesis, and fatigue after breast augmentation surgery: A single-dose, randomized, parallel-group study with methylprednisolone 125 mg, parecoxib 40 mg, and placebo
    • Romundstad L, Breivik H, Roald H et al. Methylprednisolone reduces pain, emesis, and fatigue after breast augmentation surgery: a single-dose, randomized, parallel-group study with methylprednisolone 125 mg, parecoxib 40 mg, and placebo. Anesthesia and Analgesia. 2006; 102: 418-25.
    • (2006) Anesthesia and Analgesia , vol.102 , pp. 418-425
    • Romundstad, L.1    Breivik, H.2    Roald, H.3
  • 50
    • 0024268463 scopus 로고
    • Validation study of WOMAC: A health status instrument for measuring clinically important patient relevant outcomes to antirheumatic drug therapy in patients with osteoarthritis of the hip or knee
    • Bellamy N, Buchanan WW, Goldsmith CH et al. Validation study of WOMAC: a health status instrument for measuring clinically important patient relevant outcomes to antirheumatic drug therapy in patients with osteoarthritis of the hip or knee. Journal of Rheumatology. 1988; 15: 1833-40.
    • (1988) Journal of Rheumatology , vol.15 , pp. 1833-1840
    • Bellamy, N.1    Buchanan, W.W.2    Goldsmith, C.H.3
  • 54
    • 33750840583 scopus 로고    scopus 로고
    • Developing patientreported outcome measures for pain clinical trials:IMMPACT recommendations
    • Turk DC, Dworkin RH, Burke LB et al. Developing patientreported outcome measures for pain clinical trials:IMMPACT recommendations. Pain. 2006; 125: 208-15.
    • (2006) Pain , vol.125 , pp. 208-215
    • Turk, D.C.1    Dworkin, R.H.2    Burke, L.B.3
  • 55
    • 0026877917 scopus 로고
    • The MOS 36-item short-form health survey (SF-36). I. Conceptual framework and item selection
    • Ware JE, Sherbourne CD. The MOS 36-item short-form health survey (SF-36). I. Conceptual framework and item selection. Medical Care. 1992; 30: 473-83.
    • (1992) Medical Care , vol.30 , pp. 473-483
    • Ware, J.E.1    Sherbourne, C.D.2
  • 56
    • 37549051381 scopus 로고    scopus 로고
    • Chronic nonmalignant pain patients report as poor health related quality of life as palliative cancer patients
    • Fredheim O, Kaasa S, Fayers P et al. Chronic nonmalignant pain patients report as poor health related quality of life as palliative cancer patients. Acta Anaesthesiologica Scandinavica. 2008; 52: 143-8.
    • (2008) Acta Anaesthesiologica Scandinavica , vol.52 , pp. 143-148
    • Fredheim, O.1    Kaasa, S.2    Fayers, P.3
  • 57
    • 0032694314 scopus 로고    scopus 로고
    • Reporting of adverse effects in clinical trials should be improved:Lessons from acute postoperative pain
    • Edwards JE, McQuay HJ, Moore RA, Collins SL. Reporting of adverse effects in clinical trials should be improved:lessons from acute postoperative pain. Journal of Pain and Symptom Management. 1999; 18: 427-37.
    • (1999) Journal of Pain and Symptom Management , vol.18 , pp. 427-437
    • Edwards, J.E.1    McQuay, H.J.2    Moore, R.A.3    Collins, S.L.4
  • 58
    • 0034578738 scopus 로고    scopus 로고
    • Defining the clinically important difference in pain outcome measures
    • Farrar JT, Portenoy RK, Berlin JA et al. Defining the clinically important difference in pain outcome measures. Pain. 2000; 88: 287-94.
    • (2000) Pain , vol.88 , pp. 287-294
    • Farrar, J.T.1    Portenoy, R.K.2    Berlin, J.A.3
  • 59
    • 0034748159 scopus 로고    scopus 로고
    • Clinical importance of changes in chronic pain intensity measured on an 11-point numerical pain rating scale
    • Farrar JT, Young Jr JP, LaMoreaux L et al. Clinical importance of changes in chronic pain intensity measured on an 11-point numerical pain rating scale. Pain. 2001; 94: 149-58.
    • (2001) Pain , vol.94 , pp. 149-158
    • Farrar, J.T.1    Young, J.P.2    LaMoreaux, L.3
  • 60
    • 38549181857 scopus 로고    scopus 로고
    • Interpreting the clinical importance of treatment outcomes in chronic pain clinical trials: IMMPACT recommendations
    • Dworkin RH, Turk DC, Wyrwich KW et al. Interpreting the clinical importance of treatment outcomes in chronic pain clinical trials: IMMPACT recommendations. Journal of Pain. 2008; 9: 105-21.
    • (2008) Journal of Pain , vol.9 , pp. 105-121
    • Dworkin, R.H.1    Turk, D.C.2    Wyrwich, K.W.3
  • 62
    • 33646494052 scopus 로고    scopus 로고
    • Use of the cumulative proportion of responders analysis graph to present pain data over a range of cut-off points: Making clinical trial data more understandable
    • Farrar JT, Dworkin RH, Max MB. Use of the cumulative proportion of responders analysis graph to present pain data over a range of cut-off points: making clinical trial data more understandable. Journal of Pain and Symptom Management. 2006; 31:369-77.
    • (2006) Journal of Pain and Symptom Management , vol.31 , pp. 369-377
    • Farrar, J.T.1    Dworkin, R.H.2    Max, M.B.3
  • 63
  • 65
    • 0034061095 scopus 로고    scopus 로고
    • Statistical considerations in the intentto-treat principle
    • Lachin JM. Statistical considerations in the intentto-treat principle. Controlled Clinical Trials. 2000; 21:167-89.
    • (2000) Controlled Clinical Trials , vol.21 , pp. 167-189
    • Lachin, J.M.1
  • 66
    • 4644352071 scopus 로고    scopus 로고
    • Clinical trial registration: A statement from the International Committee of Medical Journal Editors
    • De Angelis C, Drazen JM, Frizelle FA et al. Clinical trial registration: a statement from the International Committee of Medical Journal Editors. Annals of Internal Medicine. 2004; 141: 477-8.
    • (2004) Annals of Internal Medicine , vol.141 , pp. 477-478
    • De Angelis, C.1    Drazen, J.M.2    Frizelle, F.A.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.