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Volumn , Issue , 2006, Pages 627-648

Bench to bedside: Multiple actions of the PDE3 inhibitor cilostazol

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EID: 85132521865     PISSN: None     EISSN: None     Source Type: Book    
DOI: None     Document Type: Chapter
Times cited : (9)

References (122)
  • 1
    • 0029942933 scopus 로고    scopus 로고
    • Cyclic nucleotide phosphodiesterases and vascular smooth muscle
    • Poison, J.B., and S.J. Strada. 1996. Cyclic nucleotide phosphodiesterases and vascular smooth muscle. Annu Rev Pharmacol Toxicol 36:403-127.
    • (1996) Annu Rev Pharmacol Toxicol , vol.36 , pp. 403-127
    • Poison, J.B.1    Strada, S.J.2
  • 2
    • 0018640656 scopus 로고
    • Selective inhibitor of platelet cyclic adenosine monophosphate phosphodiesterase, cilostamide, inhibits platelet aggregation
    • Hidaka, H., H. Hayashi, H. Kohri, et al. 1979. Selective inhibitor of platelet cyclic adenosine monophosphate phosphodiesterase, cilostamide, inhibits platelet aggregation. J Pharmacol Exp Ther 211:26-30.
    • (1979) J Pharmacol Exp Ther , vol.211 , pp. 26-30
    • Hidaka, H.1    Hayashi, H.2    Kohri, H.3
  • 3
    • 0025093163 scopus 로고
    • Effects of isozyme-selective phosphodiesterase inhibitors on rat aorta and human platelets: Smooth muscle tone, platelet aggregation and cAMP levels
    • Lindgren, S.H., T.L. Andersson, E. Vinge, and K.E. Andersson. 1990. Effects of isozyme-selective phosphodiesterase inhibitors on rat aorta and human platelets: Smooth muscle tone, platelet aggregation and cAMP levels. Acta Physiol Scand 140:209-219.
    • (1990) Acta Physiol Scand , vol.140 , pp. 209-219
    • Lindgren, S.H.1    Andersson, T.L.2    Vinge, E.3    Andersson, K.E.4
  • 4
    • 0015231997 scopus 로고
    • Platelet aggregation. IV. Platelet phosphodiesterase and its inhibition by vasodilators
    • Vigdahl, R.L., J. Mongin, Jr., and N.R. Marquis. 1971. Platelet aggregation. IV. Platelet phosphodiesterase and its inhibition by vasodilators. Biochem Biophys Res Commun 42:1088-1094.
    • (1971) Biochem Biophys Res Commun , vol.42 , pp. 1088-1094
    • Vigdahl, R.L.1    Mongin, J.2    Marquis, N.R.3
  • 5
    • 0017894537 scopus 로고
    • Platelet aggregation and cyclic nucleotide phosphodiesterase activity in arteriosclerotic patients
    • Yamazaki, H., T. Motomiya, N. Mashimo, T. Asano, and H. Hidaka. 1978. Platelet aggregation and cyclic nucleotide phosphodiesterase activity in arteriosclerotic patients. Thromb Haemost 39:158-166.
    • (1978) Thromb Haemost , vol.39 , pp. 158-166
    • Yamazaki, H.1    Motomiya, T.2    Mashimo, N.3    Asano, T.4    Hidaka, H.5
  • 6
    • 0141943780 scopus 로고    scopus 로고
    • Cilostazol
    • ed A.D. Michelson, Academic Press, San Diego, CA
    • Ikeda, Y., T. Sudo, and Y. Kimura. 2002. Cilostazol. In Platelets, ed A.D. Michelson, 817-823. Academic Press, San Diego, CA.
    • (2002) Platelets , pp. 817-823
    • Ikeda, Y.1    Sudo, T.2    Kimura, Y.3
  • 7
    • 0035942767 scopus 로고    scopus 로고
    • Medical treatment of peripheral arterial disease and claudication
    • Hiatt, W.R. 2001. Medical treatment of peripheral arterial disease and claudication. N Engl J Med 344:1608-1621.
    • (2001) N Engl J Med , vol.344 , pp. 1608-1621
    • Hiatt, W.R.1
  • 8
    • 0035544829 scopus 로고    scopus 로고
    • Cilostazol (Pletal): A dual inhibitor of cyclic nucleotide phosphodiesterase type 3 and adenosine uptake
    • Liu, Y., Y. Shakur, M. Yoshitake, and J.J. Kambayashi. 2001. Cilostazol (Pletal): A dual inhibitor of cyclic nucleotide phosphodiesterase type 3 and adenosine uptake. Cardiovasc Drug Rev 19:369-386.
    • (2001) Cardiovasc Drug Rev , vol.19 , pp. 369-386
    • Liu, Y.1    Shakur, Y.2    Yoshitake, M.3    Kambayashi, J.J.4
  • 10
    • 0036786624 scopus 로고    scopus 로고
    • New mechanism of action for cilostazol: Interplay between adenosine and cilostazol in inhibiting platelet activation
    • Sun, B., S.N. Le, S. Lin, et al. 2002. New mechanism of action for cilostazol: Interplay between adenosine and cilostazol in inhibiting platelet activation. J Cardiovasc Pharmacol 40:577-585.
    • (2002) J Cardiovasc Pharmacol , vol.40 , pp. 577-585
    • Sun, B.1    Le, S.N.2    Lin, S.3
  • 11
    • 0034770840 scopus 로고    scopus 로고
    • Interplay between inhibition of adenosine uptake and phosphodiesterase type 3 on cardiac function by cilostazol, an agent to treat intermittent claudication
    • Wang, S., J. Cone, M. Fong, M. Yoshitake, J. Kambayashi, and Y. Liu. 2001. Interplay between inhibition of adenosine uptake and phosphodiesterase type 3 on cardiac function by cilostazol, an agent to treat intermittent claudication. J Cardiovasc Pharmacol 38:775-783.
    • (2001) J Cardiovasc Pharmacol , vol.38 , pp. 775-783
    • Wang, S.1    Cone, J.2    Fong, M.3    Yoshitake, M.4    Kambayashi, J.5    Liu, Y.6
  • 12
    • 0021990602 scopus 로고
    • Studies on 2-oxoquinoline derivatives as blood platelet aggregation inhibitors. IV. Synthesis and biological activity of the metabolites of 6-[4-(1-cyclohexyl-1H-5-tetrazolyl)butoxy]-2-oxo-1,2,3,4-tetrahydroquinoline (OPC-13013)
    • Nishi, T., F. Tabusa, T. Tanaka, T. Shimizu, and K. Nakagawa. 1985. Studies on 2-oxoquinoline derivatives as blood platelet aggregation inhibitors. IV. Synthesis and biological activity of the metabolites of 6-[4-(1-cyclohexyl-1H-5-tetrazolyl)butoxy]-2-oxo-1,2,3,4-tetrahydroquinoline (OPC-13013). Chem Pharm Bull (Tokyo) 33:1140-1147.
    • (1985) Chem Pharm Bull (Tokyo) , vol.33 , pp. 1140-1147
    • Nishi, T.1    Tabusa, F.2    Tanaka, T.3    Shimizu, T.4    Nakagawa, K.5
  • 13
    • 0036999131 scopus 로고    scopus 로고
    • Comparison of the effects of cilostazol and milrinone on cAMP-PDE activity, intracellular cAMP and calcium in the heart
    • Shakur, Y., M. Fong, J. Hensley, et al. 2002. Comparison of the effects of cilostazol and milrinone on cAMP-PDE activity, intracellular cAMP and calcium in the heart. Cardiovasc Drugs Ther 16:417-427.
    • (2002) Cardiovasc Drugs Ther , vol.16 , pp. 417-427
    • Shakur, Y.1    Fong, M.2    Hensley, J.3
  • 14
    • 0033985281 scopus 로고    scopus 로고
    • Potent effects of novel anti-platelet aggregatory cilostamide analogues on recombinant cyclic nucleotide phosphodiesterase isozyme activity
    • Sudo, T., K. Tachibana, and K. Toga, et al. 2000. Potent effects of novel anti-platelet aggregatory cilostamide analogues on recombinant cyclic nucleotide phosphodiesterase isozyme activity. Biochem Pharmacol 59:347-356.
    • (2000) Biochem Pharmacol , vol.59 , pp. 347-356
    • Sudo, T.1    Tachibana, K.2    Toga, K.3
  • 16
    • 0033836241 scopus 로고    scopus 로고
    • Inhibition of adenosine uptake and augmentation of ischemia-induced increase of interstitial adenosine by cilostazol, an agent to treat intermittent claudication
    • Liu, Y., M. Fong, J. Cone, S. Wang, M. Yoshitake, and J. Kambayashi. 2000. Inhibition of adenosine uptake and augmentation of ischemia-induced increase of interstitial adenosine by cilostazol, an agent to treat intermittent claudication. J Cardiovasc Pharmacol 36:351-360.
    • (2000) J Cardiovasc Pharmacol , vol.36 , pp. 351-360
    • Liu, Y.1    Fong, M.2    Cone, J.3    Wang, S.4    Yoshitake, M.5    Kambayashi, J.6
  • 17
    • 0026072848 scopus 로고
    • Effect of oral milrinone on mortality in severe chronic heart failure. The PROMISE Study Research Group
    • Packer, M., J.R. Carver, R.J. Rodeheffer, et al. 1991. Effect of oral milrinone on mortality in severe chronic heart failure. The PROMISE Study Research Group. N Engl J Med 325:1468-1475.
    • (1991) N Engl J Med , vol.325 , pp. 1468-1475
    • Packer, M.1    Carver, J.R.2    Rodeheffer, R.J.3
  • 18
    • 0026635293 scopus 로고    scopus 로고
    • Treatment of chronic heart failure
    • Packer, M. 1998. Treatment of chronic heart failure. Lancet 340:92-95.
    • (1998) Lancet , vol.340 , pp. 92-95
    • Packer, M.1
  • 19
    • 0032537612 scopus 로고    scopus 로고
    • FDA Panel report: January 1998
    • Thadani, U., and D.M. Roden. 1998. FDA Panel report: January 1998. Circulation 97:2295-2296.
    • (1998) Circulation , vol.97 , pp. 2295-2296
    • Thadani, U.1    Roden, D.M.2
  • 20
    • 0008505815 scopus 로고    scopus 로고
    • Cardiac physiology of adenosine
    • eds. G. Burnstock, J.G.J. Dobson, B.T. Liang, and J. Linden, Boston, MA: Kluwer Academic Publishers
    • Dobson, J.G.J., and R.A. Fenton. 1998. Cardiac physiology of adenosine. In Cardiovascular biology of purines, eds. G. Burnstock, J.G.J. Dobson, B.T. Liang, and J. Linden, 21-39. Boston, MA: Kluwer Academic Publishers.
    • (1998) Cardiovascular biology of purines , pp. 21-39
    • Dobson, J.G.J.1    Fenton, R.A.2
  • 21
    • 0033963829 scopus 로고    scopus 로고
    • Phosphatase inhibitor cantharidin blocks adenosine A(1) receptor anti-adrenergic effect in rat cardiac myocytes
    • Narayan, P., R.M. Mentzer, Jr., and R.D. Lasley. 2000. Phosphatase inhibitor cantharidin blocks adenosine A(1) receptor anti-adrenergic effect in rat cardiac myocytes. Am J Physiol Heart Circ Physiol 278:H1-H7.
    • (2000) Am J Physiol Heart Circ Physiol , vol.278 , pp. H1-H7
    • Narayan, P.1    Mentzer, R.M.2    Lasley, R.D.3
  • 22
    • 0032830573 scopus 로고    scopus 로고
    • Comparison of the effects of cilostazol and milrinone on intracellular cAMP levels and cellular function in platelets and cardiac cells
    • Cone, J., S. Wang, N. Tandon, et al. 1999. Comparison of the effects of cilostazol and milrinone on intracellular cAMP levels and cellular function in platelets and cardiac cells. J Cardiovasc Pharmacol 34:497-504.
    • (1999) J Cardiovasc Pharmacol , vol.34 , pp. 497-504
    • Cone, J.1    Wang, S.2    Tandon, N.3
  • 23
    • 0021849433 scopus 로고
    • Effect of cilostazol on platelet aggregation and experimental thrombosis
    • Kimura, Y., T. Tani, T. Kanbe, and K. Watanabe. 1985. Effect of cilostazol on platelet aggregation and experimental thrombosis. Arzneimittelforschung 35:1144-1149.
    • (1985) Arzneimittelforschung , vol.35 , pp. 1144-1149
    • Kimura, Y.1    Tani, T.2    Kanbe, T.3    Watanabe, K.4
  • 24
    • 0024316881 scopus 로고
    • Effects of cilostazol on platelet function
    • Uehara, S., and A. Hirayama. 1989. Effects of cilostazol on platelet function. Arzneimittelforschung 39:1531-1534.
    • (1989) Arzneimittelforschung , vol.39 , pp. 1531-1534
    • Uehara, S.1    Hirayama, A.2
  • 25
    • 0026478204 scopus 로고
    • Pharmacological manipulation of tissue cyclic AMP by inhibitors. Effects of phosphodiesterase inhibitors on the functions of platelets and vascular endothelial cells
    • Tani, T., K. Sakurai, Y. Kimura, T. Ishikawa, and H. Hidaka. 1992. Pharmacological manipulation of tissue cyclic AMP by inhibitors. Effects of phosphodiesterase inhibitors on the functions of platelets and vascular endothelial cells. Adv Second Messenger Phosphoprotein Res 25:215-227.
    • (1992) Adv Second Messenger Phosphoprotein Res , vol.25 , pp. 215-227
    • Tani, T.1    Sakurai, K.2    Kimura, Y.3    Ishikawa, T.4    Hidaka, H.5
  • 26
    • 0035868374 scopus 로고    scopus 로고
    • Inhibition of platelet aggregation and the release of P-selectin from platelets by cilostazol
    • Kariyazono, H., K. Nakamura, T. Shinkawa, T. Yamaguchi, R. Sakata, and K. Yamada. 2001. Inhibition of platelet aggregation and the release of P-selectin from platelets by cilostazol. Thromb Res 101:445-453.
    • (2001) Thromb Res , vol.101 , pp. 445-453
    • Kariyazono, H.1    Nakamura, K.2    Shinkawa, T.3    Yamaguchi, T.4    Sakata, R.5    Yamada, K.6
  • 27
    • 0033165938 scopus 로고    scopus 로고
    • Comparative study of antiplatelet drugs in vitro: Distinct effects of cAMP-elevating drugs and GPIIb/IIIa antagonists on thrombin-induced platelet responses
    • Matsumoto, Y., K. Marukawa, H. Okumura, T. Adachi, T. Tani, and Y. Kimura. 1999. Comparative study of antiplatelet drugs in vitro: Distinct effects of cAMP-elevating drugs and GPIIb/IIIa antagonists on thrombin-induced platelet responses. Thromb Res 95:19-29.
    • (1999) Thromb Res , vol.95 , pp. 19-29
    • Matsumoto, Y.1    Marukawa, K.2    Okumura, H.3    Adachi, T.4    Tani, T.5    Kimura, Y.6
  • 28
    • 0031567714 scopus 로고    scopus 로고
    • Inhibition of shear stress-induced platelet aggregation by cilostazol, a specific inhibitor of cGMP-inhibited phosphodiesterase, in vitro and ex vivo
    • Minami, N., Y. Suzuki, M. Yamamoto, et al. 1997. Inhibition of shear stress-induced platelet aggregation by cilostazol, a specific inhibitor of cGMP-inhibited phosphodiesterase, in vitro and ex vivo. Life Sci 61:L-9.
    • (1997) Life Sci , vol.61 , pp. L-9
    • Minami, N.1    Suzuki, Y.2    Yamamoto, M.3
  • 29
    • 0034192024 scopus 로고    scopus 로고
    • Increased platelet aggregability in response to shear stress in acute myocardial infarction and its inhibition by combined therapy with aspirin and cilostazol after coronary intervention
    • Tanigawa, T., M. Nishikawa, T. Kitai, et al. 2000. Increased platelet aggregability in response to shear stress in acute myocardial infarction and its inhibition by combined therapy with aspirin and cilostazol after coronary intervention. Am J Cardiol 85:1054-1059.
    • (2000) Am J Cardiol , vol.85 , pp. 1054-1059
    • Tanigawa, T.1    Nishikawa, M.2    Kitai, T.3
  • 30
    • 0021876267 scopus 로고
    • Clinical effects of oral cilostazol on suppression of platelet function in patients with cerebrovascular disease
    • Yasunaga, K., and K. Mase. 1985. Clinical effects of oral cilostazol on suppression of platelet function in patients with cerebrovascular disease. Arzneimittelforschung 35:1186-1188.
    • (1985) Arzneimittelforschung , vol.35 , pp. 1186-1188
    • Yasunaga, K.1    Mase, K.2
  • 31
    • 0036224424 scopus 로고    scopus 로고
    • Pharmacokinetic and pharmacodynamic modeling of the antiplatelet and cardiovascular effects of cilostazol in healthy humans
    • Woo, S.K., W.K. Kang, and K.I. Kwon. 2002. Pharmacokinetic and pharmacodynamic modeling of the antiplatelet and cardiovascular effects of cilostazol in healthy humans. Clin Pharmacol Ther 71:246-252.
    • (2002) Clin Pharmacol Ther , vol.71 , pp. 246-252
    • Woo, S.K.1    Kang, W.K.2    Kwon, K.I.3
  • 32
    • 0021800276 scopus 로고
    • Hemodynamic effect of cilostazol on increasing peripheral blood flow in arteriosclerosis obliterans
    • Yasuda, K., M. Sakuma, and T. Tanabe. 1985. Hemodynamic effect of cilostazol on increasing peripheral blood flow in arteriosclerosis obliterans. Arzneimittelforschung 35:1198-1200.
    • (1985) Arzneimittelforschung , vol.35 , pp. 1198-1200
    • Yasuda, K.1    Sakuma, M.2    Tanabe, T.3
  • 33
    • 0027468538 scopus 로고
    • Cilostazol, a novel cyclic AMP phosphodiesterase inhibitor, prevents reocclusion after coronary arterial thrombolysis with recombinant tissue-type plasminogen activator
    • Saitoh, S., T. Saito, A. Otake, et al. 1993. Cilostazol, a novel cyclic AMP phosphodiesterase inhibitor, prevents reocclusion after coronary arterial thrombolysis with recombinant tissue-type plasminogen activator. Arterioscler Thromb 13:563-570.
    • (1993) Arterioscler Thromb , vol.13 , pp. 563-570
    • Saitoh, S.1    Saito, T.2    Otake, A.3
  • 34
    • 0032700659 scopus 로고    scopus 로고
    • Effect of cilostazol, a phosphodiesterase III inhibitor, on experimental thrombosis in the porcine carotid artery
    • Kohda, N., T. Tani, S. Nakayama, et al. 1999. Effect of cilostazol, a phosphodiesterase III inhibitor, on experimental thrombosis in the porcine carotid artery. Thromb Res 96:261-268.
    • (1999) Thromb Res , vol.96 , pp. 261-268
    • Kohda, N.1    Tani, T.2    Nakayama, S.3
  • 35
    • 20044371861 scopus 로고    scopus 로고
    • Antiplatelet and antithrombotic activity of cilostazol is potentiated by dipyridamole in rabbits and dissociated from bleeding time prolongation
    • Li, H., J. Cone, M. Fong, J. Kambayashi, M. Yoshitake, and Y. Liu. 2005. Antiplatelet and antithrombotic activity of cilostazol is potentiated by dipyridamole in rabbits and dissociated from bleeding time prolongation. Cardiovasc Drugs Ther 19:41-48.
    • (2005) Cardiovasc Drugs Ther , vol.19 , pp. 41-48
    • Li, H.1    Cone, J.2    Fong, M.3    Kambayashi, J.4    Yoshitake, M.5    Liu, Y.6
  • 36
    • 0023195289 scopus 로고
    • Comparison of the inhibitory effects of cilostazol, acetylsalicylic acid and ticlopidine on platelet functions ex vivo. Randomized, doubleblind cross-over study
    • Ikeda, Y., M. Kikuchi, H. Murakami, et al. 1987. Comparison of the inhibitory effects of cilostazol, acetylsalicylic acid and ticlopidine on platelet functions ex vivo. Randomized, doubleblind cross-over study. Arzneimittelforschung 37:563-566.
    • (1987) Arzneimittelforschung , vol.37 , pp. 563-566
    • Ikeda, Y.1    Kikuchi, M.2    Murakami, H.3
  • 37
    • 0033748474 scopus 로고    scopus 로고
    • Assessment of antithrombotic agents using the platelet aggregation test
    • Tanemoto, K., Y. Kanaoka, and M. Kuinose. 2000. Assessment of antithrombotic agents using the platelet aggregation test. Cur Ther Res 61(11):798-806.
    • (2000) Cur Ther Res , vol.61 , Issue.11 , pp. 798-806
    • Tanemoto, K.1    Kanaoka, Y.2    Kuinose, M.3
  • 38
    • 0032725094 scopus 로고    scopus 로고
    • Antiplatelet therapy using cilostazol, a specific PDE3 inhibitor
    • Ikeda, Y. 1999. Antiplatelet therapy using cilostazol, a specific PDE3 inhibitor. Thromb Haemost 82:435-438.
    • (1999) Thromb Haemost , vol.82 , pp. 435-438
    • Ikeda, Y.1
  • 39
    • 0025305041 scopus 로고
    • Potentiation of anti-platelet aggregating activity of cilostazol with vascular endothelial cells
    • Igawa, T., T. Tani, T. Chijiwa, et al. 1990. Potentiation of anti-platelet aggregating activity of cilostazol with vascular endothelial cells. Thromb Res 57:617-623.
    • (1990) Thromb Res , vol.57 , pp. 617-623
    • Igawa, T.1    Tani, T.2    Chijiwa, T.3
  • 40
    • 0006016786 scopus 로고    scopus 로고
    • Dipyridamole
    • ed. A.D. Michelson, New York: Academic Press
    • Eisert, W.G. 2002. Dipyridamole. In Platelets, ed. A.D. Michelson, 803-815. New York: Academic Press.
    • (2002) Platelets , pp. 803-815
    • Eisert, W.G.1
  • 41
    • 3242751979 scopus 로고    scopus 로고
    • Cilostazol and dipyridamole synergistically inhibit human platelet aggregation
    • Liu, Y., J. Cone, S.N. Le, et al. 2004. Cilostazol and dipyridamole synergistically inhibit human platelet aggregation. J Cardiovasc Pharmacol 44:266-273.
    • (2004) J Cardiovasc Pharmacol , vol.44 , pp. 266-273
    • Liu, Y.1    Cone, J.2    Le, S.N.3
  • 42
    • 2442553637 scopus 로고    scopus 로고
    • Platelet activation markers, microparticles and soluble adhesion molecules are elevated in patients with arteriosclerosis obliterans: Therapeutic effects by cilostazol and potentiation by dipyridamole
    • Nomura, S., N. Inami, T. Iwasaka, and Y. Liu. 2004. Platelet activation markers, microparticles and soluble adhesion molecules are elevated in patients with arteriosclerosis obliterans: Therapeutic effects by cilostazol and potentiation by dipyridamole. Platelets 15:167-172.
    • (2004) Platelets , vol.15 , pp. 167-172
    • Nomura, S.1    Inami, N.2    Iwasaka, T.3    Liu, Y.4
  • 43
    • 3142773364 scopus 로고    scopus 로고
    • A randomized crossover comparative study of aspirin, cilostazol and clopidogrel in normal controls: Analysis with quantitative bleeding time and platelet aggregation test
    • Kim, J.S., K.S. Lee, Y.I. Kim, Y. Tamai, R. Nakahata, and H. Takami. 2004. A randomized crossover comparative study of aspirin, cilostazol and clopidogrel in normal controls: Analysis with quantitative bleeding time and platelet aggregation test. J Clin Neurosci 11:600-602.
    • (2004) J Clin Neurosci , vol.11 , pp. 600-602
    • Kim, J.S.1    Lee, K.S.2    Kim, Y.I.3    Tamai, Y.4    Nakahata, R.5    Takami, H.6
  • 44
    • 0141954237 scopus 로고    scopus 로고
    • Managing PAD with multiple platelet inhibitors: The effect of combination therapy on bleeding time
    • Wilhite, D.B., A.J. Comerota, F.A. Schmieder, R.C. Throm, J.P. Gaughan, and R.A. Koneti. 2003. Managing PAD with multiple platelet inhibitors: The effect of combination therapy on bleeding time. J Vasc Surg 38:710-713.
    • (2003) J Vasc Surg , vol.38 , pp. 710-713
    • Wilhite, D.B.1    Comerota, A.J.2    Schmieder, F.A.3    Throm, R.C.4    Gaughan, J.P.5    Koneti, R.A.6
  • 45
    • 0342369574 scopus 로고    scopus 로고
    • Comparison of the effects of acetylsalicylic acid, ticlopidine and cilostazol on primary hemostasis using a quantitative bleeding time test apparatus
    • Tamai, Y., H. Takami, R. Nakahata, F. Ono, and A. Munakata. 1999. Comparison of the effects of acetylsalicylic acid, ticlopidine and cilostazol on primary hemostasis using a quantitative bleeding time test apparatus. Haemostasis 29:269-276.
    • (1999) Haemostasis , vol.29 , pp. 269-276
    • Tamai, Y.1    Takami, H.2    Nakahata, R.3    Ono, F.4    Munakata, A.5
  • 46
    • 0033510192 scopus 로고    scopus 로고
    • Interaction potential and tolerability of the coadministration of cilostazol and aspirin
    • Mallikaarjun, S., W.P. Forbes, and S.L. Bramer. 1999. Interaction potential and tolerability of the coadministration of cilostazol and aspirin. Clin Pharmacokinet 37 (Suppl 2):87-93.
    • (1999) Clin Pharmacokinet , vol.37 , Issue.2 , pp. 87-93
    • Mallikaarjun, S.1    Forbes, W.P.2    Bramer, S.L.3
  • 47
    • 84904985596 scopus 로고
    • Effects of cilostazol (OPC-13013) on arachidonic acid metabolism
    • Nagakawa, Y., Y. Omaki, and H. Orimo. 1986. Effects of cilostazol (OPC-13013) on arachidonic acid metabolism. Jpn Pharmacol Ther 14:6319-6324.
    • (1986) Jpn Pharmacol Ther , vol.14 , pp. 6319-6324
    • Nagakawa, Y.1    Omaki, Y.2    Orimo, H.3
  • 48
    • 10944266061 scopus 로고    scopus 로고
    • The phosphodiesterase 3 inhibitor cilostazol dilates large cerebral arteries in humans without affecting regional cerebral blood flow
    • Birk, S., C. Kruuse, K.A. Petersen, O. Jonassen, P. Tfelt-Hansen, and J. Olesen. 2004. The phosphodiesterase 3 inhibitor cilostazol dilates large cerebral arteries in humans without affecting regional cerebral blood flow. J Cereb Blood Flow Metab 24:1352-1358.
    • (2004) J Cereb Blood Flow Metab , vol.24 , pp. 1352-1358
    • Birk, S.1    Kruuse, C.2    Petersen, K.A.3    Jonassen, O.4    Tfelt-Hansen, P.5    Olesen, J.6
  • 49
    • 85132504654 scopus 로고    scopus 로고
    • Cilostazol increases tissue blood flow and interstitial adenosine levels in stimulated rabbit gastrocnemius muscle [abstract]
    • Wang, S., J. Cone, M. Fong, M. Yoshitake, J. Kambayashi, and Y. Liu. 2005. Cilostazol increases tissue blood flow and interstitial adenosine levels in stimulated rabbit gastrocnemius muscle [abstract]. J Mol Cell Cardio 38:868.
    • (2005) J Mol Cell Cardio , vol.38 , pp. 868
    • Wang, S.1    Cone, J.2    Fong, M.3    Yoshitake, M.4    Kambayashi, J.5    Liu, Y.6
  • 50
    • 0026690069 scopus 로고
    • Effect of cilostazol, a cyclic AMP phosphodiesterase inhibitor, on the proliferation of rat aortic smooth muscle cells in culture
    • Takahashi, S., K. Oida, R. Fujiwara, et al. 1992. Effect of cilostazol, a cyclic AMP phosphodiesterase inhibitor, on the proliferation of rat aortic smooth muscle cells in culture. J Cardiovasc Pharmacol 20:900-906.
    • (1992) J Cardiovasc Pharmacol , vol.20 , pp. 900-906
    • Takahashi, S.1    Oida, K.2    Fujiwara, R.3
  • 51
    • 0033617216 scopus 로고    scopus 로고
    • OPC-13013, a cyclic nucleotide phosphodiesterase type III, inhibitor, inhibits cell proliferation and transdifferentiation of cultured rat hepatic stellate cells
    • Shimizu, E., Y. Kobayashi, Y. Oki, T. Kawasaki, T. Yoshimi, and H. Nakamura. 1999. OPC-13013, a cyclic nucleotide phosphodiesterase type III, inhibitor, inhibits cell proliferation and transdifferentiation of cultured rat hepatic stellate cells. Life Sci 64:2081-2088.
    • (1999) Life Sci , vol.64 , pp. 2081-2088
    • Shimizu, E.1    Kobayashi, Y.2    Oki, Y.3    Kawasaki, T.4    Yoshimi, T.5    Nakamura, H.6
  • 52
    • 0033977303 scopus 로고    scopus 로고
    • Cyclic AMP inhibited proliferation of human aortic vascular smooth muscle cells, accompanied by induction of p53 and p21
    • Hayashi, S., R. Morishita, H. Matsushita, et al. 2000. Cyclic AMP inhibited proliferation of human aortic vascular smooth muscle cells, accompanied by induction of p53 and p21. Hypertension 35:237-243.
    • (2000) Hypertension , vol.35 , pp. 237-243
    • Hayashi, S.1    Morishita, R.2    Matsushita, H.3
  • 53
    • 20144384243 scopus 로고    scopus 로고
    • Cilostazol inhibits vascular smooth muscle cell growth by downregulation of the transcription factor E2F
    • Kim, M.J., K.G. Park, K.M. Lee, et al. 2005. Cilostazol inhibits vascular smooth muscle cell growth by downregulation of the transcription factor E2F. Hypertension 45:552-556.
    • (2005) Hypertension , vol.45 , pp. 552-556
    • Kim, M.J.1    Park, K.G.2    Lee, K.M.3
  • 54
    • 0032698044 scopus 로고    scopus 로고
    • Cyclic nucleotide phosphodiesterases and human arterial smooth muscle cell proliferation
    • Rybalkin, S.D., and K.E. Bornfeldt. 1999. Cyclic nucleotide phosphodiesterases and human arterial smooth muscle cell proliferation. Thromb Haemost 82:424-434.
    • (1999) Thromb Haemost , vol.82 , pp. 424-434
    • Rybalkin, S.D.1    Bornfeldt, K.E.2
  • 55
    • 0031577567 scopus 로고    scopus 로고
    • The effect of cilostazol, a cyclic nucleotide phosphodiesterase III inhibitor, on heparin-binding EGF-like growth factor expression in macrophages and vascular smooth muscle cells
    • Kayanoki, Y., W. Che, S. Kawata, Y. Matsuzawa, S. Higashiyama, and N. Taniguchi. 1997. The effect of cilostazol, a cyclic nucleotide phosphodiesterase III inhibitor, on heparin-binding EGF-like growth factor expression in macrophages and vascular smooth muscle cells. Biochem Biophys Res Commun 238:478-481.
    • (1997) Biochem Biophys Res Commun , vol.238 , pp. 478-481
    • Kayanoki, Y.1    Che, W.2    Kawata, S.3    Matsuzawa, Y.4    Higashiyama, S.5    Taniguchi, N.6
  • 56
    • 4644287449 scopus 로고    scopus 로고
    • Cilostazol inhibits leukocyte integrin Mac-1, leading to a potential reduction in restenosis after coronary stent implantation
    • Inoue, T., T. Uchida, M. Sakuma, et al. 2004. Cilostazol inhibits leukocyte integrin Mac-1, leading to a potential reduction in restenosis after coronary stent implantation. J Am Coll Cardiol 44:1408-1414.
    • (2004) J Am Coll Cardiol , vol.44 , pp. 1408-1414
    • Inoue, T.1    Uchida, T.2    Sakuma, M.3
  • 57
    • 8544241710 scopus 로고    scopus 로고
    • Role of hepatocyte growth factor in endothelial regulation: Prevention of high D-glucose-induced endothelial cell death by prostaglandins and phosphodiesterase type 3 inhibitor
    • Morishita, R., J. Higaki, S.I. Hayashi, et al. 1997. Role of hepatocyte growth factor in endothelial regulation: Prevention of high D-glucose-induced endothelial cell death by prostaglandins and phosphodiesterase type 3 inhibitor. Diabetologia 40:1053-1061.
    • (1997) Diabetologia , vol.40 , pp. 1053-1061
    • Morishita, R.1    Higaki, J.2    Hayashi, S.I.3
  • 58
    • 0034853165 scopus 로고    scopus 로고
    • Differential effects of cilostazol and pentoxifylline on vascular endothelial growth factor in patients with intermittent claudication
    • Lee, T.M., S.F. Su, C.H. Tsai, Y.T. Lee, and S.S. Wang. 2001. Differential effects of cilostazol and pentoxifylline on vascular endothelial growth factor in patients with intermittent claudication. Clin Sci (Lond) 101:305-311.
    • (2001) Clin Sci (Lond) , vol.101 , pp. 305-311
    • Lee, T.M.1    Su, S.F.2    Tsai, C.H.3    Lee, Y.T.4    Wang, S.S.5
  • 59
    • 9844267305 scopus 로고    scopus 로고
    • Cilostazol, a cAMP phosphodiesterase inhibitor, attenuates the production of monocyte chemoattractant protein-1 in response to tumor necrosis factor-alpha in vascular endothelial cells
    • Nishio, Y., A. Kashiwagi, N. Takahara, H. Hidaka, and R. Kikkawa. 1997. Cilostazol, a cAMP phosphodiesterase inhibitor, attenuates the production of monocyte chemoattractant protein-1 in response to tumor necrosis factor-alpha in vascular endothelial cells. Horm Metab Res 29:491-495.
    • (1997) Horm Metab Res , vol.29 , pp. 491-495
    • Nishio, Y.1    Kashiwagi, A.2    Takahara, N.3    Hidaka, H.4    Kikkawa, R.5
  • 60
    • 4143075782 scopus 로고    scopus 로고
    • Cilostazol inhibits high glucose-mediated endothelial-neutrophil adhesion by decreasing adhesion molecule expression via NO production
    • Omi, H., N. Okayama, M. Shimizu, et al. 2004. Cilostazol inhibits high glucose-mediated endothelial-neutrophil adhesion by decreasing adhesion molecule expression via NO production. Microvasc Res 68:119-125.
    • (2004) Microvasc Res , vol.68 , pp. 119-125
    • Omi, H.1    Okayama, N.2    Shimizu, M.3
  • 61
    • 0032890246 scopus 로고    scopus 로고
    • Effects of a single local administration of cilostazol on neointimal formation in balloon-injured rat carotid artery
    • Ishizaka, N., J. Taguchi, Y. Kimura, et al. 1999. Effects of a single local administration of cilostazol on neointimal formation in balloon-injured rat carotid artery. Atherosclerosis 142:41-46.
    • (1999) Atherosclerosis , vol.142 , pp. 41-46
    • Ishizaka, N.1    Taguchi, J.2    Kimura, Y.3
  • 62
    • 0028850075 scopus 로고
    • Pharmacologic treatment of intimal hyperplasia after metallic stent placement in the peripheral arteries. An experimental study
    • Kubota, Y., K. Kichikawa, H. Uchida, et al. 1995. Pharmacologic treatment of intimal hyperplasia after metallic stent placement in the peripheral arteries. An experimental study. Invest Radiol 30:532-537.
    • (1995) Invest Radiol , vol.30 , pp. 532-537
    • Kubota, Y.1    Kichikawa, K.2    Uchida, H.3
  • 63
    • 0034883805 scopus 로고    scopus 로고
    • Inhibition of neointimal formation after balloon injury by cilostazol, accompanied by improvement of endothelial dysfunction and induction of hepatocyte growth factor in rat diabetes model
    • Aoki, M., R. Morishita, S. Hayashi, et al. 2001. Inhibition of neointimal formation after balloon injury by cilostazol, accompanied by improvement of endothelial dysfunction and induction of hepatocyte growth factor in rat diabetes model. Diabetologia 44:1034-1042.
    • (2001) Diabetologia , vol.44 , pp. 1034-1042
    • Aoki, M.1    Morishita, R.2    Hayashi, S.3
  • 64
    • 20944448650 scopus 로고    scopus 로고
    • Cilostazol reduces atherosclerosis by inhibition of superoxide and tumor necrosis factor-alpha formation in low-density lipoprotein receptor-null mice fed high cholesterol
    • Lee, J.H., G.T. Oh, S.Y. Park, et al. 2005. Cilostazol reduces atherosclerosis by inhibition of superoxide and tumor necrosis factor-alpha formation in low-density lipoprotein receptor-null mice fed high cholesterol. J Pharmacol Exp Ther 313:502-509.
    • (2005) J Pharmacol Exp Ther , vol.313 , pp. 502-509
    • Lee, J.H.1    Oh, G.T.2    Park, S.Y.3
  • 65
    • 0031649108 scopus 로고    scopus 로고
    • Effect of the novel antiplatelet agent cilostazol on plasma lipoproteins in patients with intermittent claudication
    • Elam, M.B., J. Heckman, J.R. Crouse, et al. 1998. Effect of the novel antiplatelet agent cilostazol on plasma lipoproteins in patients with intermittent claudication. Arterioscler Thromb Vasc Biol 18:1942-1947.
    • (1998) Arterioscler Thromb Vasc Biol , vol.18 , pp. 1942-1947
    • Elam, M.B.1    Heckman, J.2    Crouse, J.R.3
  • 66
    • 0344741545 scopus 로고    scopus 로고
    • Reduction of remnant lipoprotein cholesterol concentrations by cilostazol in patients with intermittent claudication
    • Wang, T., M.B. Elam, W.P. Forbes, J. Zhong, and K. Nakajima. 2003. Reduction of remnant lipoprotein cholesterol concentrations by cilostazol in patients with intermittent claudication. Atherosclerosis 171:337-342.
    • (2003) Atherosclerosis , vol.171 , pp. 337-342
    • Wang, T.1    Elam, M.B.2    Forbes, W.P.3    Zhong, J.4    Nakajima, K.5
  • 67
    • 0027048730 scopus 로고
    • Reduction of low density lipoprotein by cilostazol in the non-insulin dependent diabetic patient
    • Tamai, T., A. Shimada, H. Maeda, et al. 1992. Reduction of low density lipoprotein by cilostazol in the non-insulin dependent diabetic patient. Jap Pharmacol Ther 20:241-248.
    • (1992) Jap Pharmacol Ther , vol.20 , pp. 241-248
    • Tamai, T.1    Shimada, A.2    Maeda, H.3
  • 68
    • 0030052944 scopus 로고    scopus 로고
    • Effects of cilostazol on the lipid metabolism in patients with hypertriglyceridemia
    • Watanabe, N., Y. Ishikawa, Y. Kitagawa, et al. 1996. Effects of cilostazol on the lipid metabolism in patients with hypertriglyceridemia. Jap Pharmacol Ther 24:127-132.
    • (1996) Jap Pharmacol Ther , vol.24 , pp. 127-132
    • Watanabe, N.1    Ishikawa, Y.2    Kitagawa, Y.3
  • 69
    • 0030800572 scopus 로고    scopus 로고
    • The effects of cilostazol on serum lipid metabolism and ASO in NIDDM with hypertriglyceridemia
    • Ishikawa, M., Y. Yamada, C. Hirose, D. Tujino, K. Hoshi, and N. Saitou. 1997. The effects of cilostazol on serum lipid metabolism and ASO in NIDDM with hypertriglyceridemia. Ther Res 18:198-204.
    • (1997) Ther Res , vol.18 , pp. 198-204
    • Ishikawa, M.1    Yamada, Y.2    Hirose, C.3    Tujino, D.4    Hoshi, K.5    Saitou, N.6
  • 70
    • 0141896872 scopus 로고    scopus 로고
    • Effects of cilostazol on serum lipoprotein concentrations and particle size of low-density lipoproteins in patients with dyslipidemic NIDDM
    • Mishima, Y., A. Kuyama, M. Ando, M. Kibata, and T. Ishioka. 2000. Effects of cilostazol on serum lipoprotein concentrations and particle size of low-density lipoproteins in patients with dyslipidemic NIDDM. J Jap Atherosclerosis Soc 27:17-22.
    • (2000) J Jap Atherosclerosis Soc , vol.27 , pp. 17-22
    • Mishima, Y.1    Kuyama, A.2    Ando, M.3    Kibata, M.4    Ishioka, T.5
  • 71
    • 17844391815 scopus 로고    scopus 로고
    • Effect of cilostazol on lipid, uric acid and glucose metabolism in patients with impaired glucose tolerance or type 2 diabetes mellitus: A double-blind, placebo-controlled study
    • Takayoshi, T., O. Shinichi, A. Ryuzo, et al. 2001. Effect of cilostazol on lipid, uric acid and glucose metabolism in patients with impaired glucose tolerance or type 2 diabetes mellitus: A double-blind, placebo-controlled study. Clinical Drug Investig 21:325-335.
    • (2001) Clinical Drug Investig , vol.21 , pp. 325-335
    • Takayoshi, T.1    Shinichi, O.2    Ryuzo, A.3
  • 72
    • 0036799613 scopus 로고    scopus 로고
    • Cilostazol, a potent phosphodiesterase type III inhibitor, selectively increases antiatherogenic high-density lipoprotein subclass LpA-I and improves postprandial lipemia in patients with type 2 diabetes mellitus
    • Ikewaki, K., K. Mochizuki, M. Iwasaki, R. Nishide, S. Mochizuki, and N. Tada. 2002. Cilostazol, a potent phosphodiesterase type III inhibitor, selectively increases antiatherogenic high-density lipoprotein subclass LpA-I and improves postprandial lipemia in patients with type 2 diabetes mellitus. Metabolism 51:1348-1354.
    • (2002) Metabolism , vol.51 , pp. 1348-1354
    • Ikewaki, K.1    Mochizuki, K.2    Iwasaki, M.3    Nishide, R.4    Mochizuki, S.5    Tada, N.6
  • 73
    • 0037293164 scopus 로고    scopus 로고
    • Effects of cilostazol on serum lipid concentrations and plasma fatty acid composition in type 2 diabetic patients with peripheral vascular disease
    • Nakamura, N., T. Hamazaki, H. Johkaji, et al. 2003. Effects of cilostazol on serum lipid concentrations and plasma fatty acid composition in type 2 diabetic patients with peripheral vascular disease. Clin Exp Med 2:180-184.
    • (2003) Clin Exp Med , vol.2 , pp. 180-184
    • Nakamura, N.1    Hamazaki, T.2    Johkaji, H.3
  • 74
    • 0033821449 scopus 로고    scopus 로고
    • Cilostazol, a selective type III phosphodiesterase inhibitor, decreases triglyceride and increases HDL cholesterol levels by increasing lipoprotein lipase activity in rats
    • Tani, T., K. Uehara, T. Sudo, K. Marukawa, Y. Yasuda, and Y. Kimura. 2000. Cilostazol, a selective type III phosphodiesterase inhibitor, decreases triglyceride and increases HDL cholesterol levels by increasing lipoprotein lipase activity in rats. Atherosclerosis 152:299-305.
    • (2000) Atherosclerosis , vol.152 , pp. 299-305
    • Tani, T.1    Uehara, K.2    Sudo, T.3    Marukawa, K.4    Yasuda, Y.5    Kimura, Y.6
  • 75
    • 0022445634 scopus 로고
    • Protein kinase activation of heparin-releasable lipoprotein lipase in rat heart
    • Oscai, L.B., R.A. Caruso, and W.K. Palmer. 1986. Protein kinase activation of heparin-releasable lipoprotein lipase in rat heart. Biochem Biophys Res Commun 135:196-200.
    • (1986) Biochem Biophys Res Commun , vol.135 , pp. 196-200
    • Oscai, L.B.1    Caruso, R.A.2    Palmer, W.K.3
  • 76
    • 0031710063 scopus 로고    scopus 로고
    • Involvement of adenosine in vanadate-stimulated release of lipoprotein lipase activity
    • Motoyashiki, T., M. Fukamachi, T. Morita, H. Shiomi, and H. Ueki. 1998. Involvement of adenosine in vanadate-stimulated release of lipoprotein lipase activity. Biol Pharm Bull 21:889-892.
    • (1998) Biol Pharm Bull , vol.21 , pp. 889-892
    • Motoyashiki, T.1    Fukamachi, M.2    Morita, T.3    Shiomi, H.4    Ueki, H.5
  • 77
    • 0037044773 scopus 로고    scopus 로고
    • The translational regulation of lipoprotein lipase by epinephrine involves an RNA binding complex including the catalytic subunit of protein kinase A
    • Ranganathan, G., D. Phan, I.D. Pokrovskaya, J.E. McEwen, C. Li, and P.A. Kern. 2002. The translational regulation of lipoprotein lipase by epinephrine involves an RNA binding complex including the catalytic subunit of protein kinase A. J Biol Chem 277:43281-43287.
    • (2002) J Biol Chem , vol.277 , pp. 43281-43287
    • Ranganathan, G.1    Phan, D.2    Pokrovskaya, I.D.3    McEwen, J.E.4    Li, C.5    Kern, P.A.6
  • 78
    • 0344725002 scopus 로고
    • Adenosine analogs inhibit adipocyte adenylate cyclase by a GTP-dependent process: Basis for actions of adenosine and methylxanthines on cyclic AMP production and lipolysis
    • Londos, C., D.M. Cooper, W. Schlegel, and M. Rodbell. 1978. Adenosine analogs inhibit adipocyte adenylate cyclase by a GTP-dependent process: Basis for actions of adenosine and methylxanthines on cyclic AMP production and lipolysis. Proc Natl Acad Sci USA 75:5362-5366.
    • (1978) Proc Natl Acad Sci USA , vol.75 , pp. 5362-5366
    • Londos, C.1    Cooper, D.M.2    Schlegel, W.3    Rodbell, M.4
  • 79
    • 0028180043 scopus 로고
    • Coupling of inhibitory receptors with Gi-proteins in hamster adipocytes: Comparison between adenosine A1 receptor and alpha 2-adrenoceptor
    • Larrouy, D., A. Remaury, D. Daviaud, and M. Lafontan. 1994. Coupling of inhibitory receptors with Gi-proteins in hamster adipocytes: Comparison between adenosine A1 receptor and alpha 2-adrenoceptor. Eur J Pharmacol 267:225-232.
    • (1994) Eur J Pharmacol , vol.267 , pp. 225-232
    • Larrouy, D.1    Remaury, A.2    Daviaud, D.3    Lafontan, M.4
  • 80
    • 0030776502 scopus 로고    scopus 로고
    • Differential regulation by tumor necrosis factor-alpha of beta1-, beta2-, and beta3-adrenoreceptor gene expression in 3T3-F442A adipocytes
    • Hadri, K.E., A. Courtalon, X. Gauthereau, A.M. Chambaut-Guerin, J. Pairault, and B. Feve. 1997. Differential regulation by tumor necrosis factor-alpha of beta1-, beta2-, and beta3-adrenoreceptor gene expression in 3T3-F442A adipocytes. JBiolChem 272:24514-24521.
    • (1997) JBiolChem , vol.272 , pp. 24514-24521
    • Hadri, K.E.1    Courtalon, A.2    Gauthereau, X.3    Chambaut-Guerin, A.M.4    Pairault, J.5    Feve, B.6
  • 81
    • 0036261264 scopus 로고    scopus 로고
    • TNFalpha expression of subcutaneous adipose tissue in obese and morbid obese females: Relationship to adipocyte LPL activity and leptin synthesis
    • Bullo, M., P. Garcia-Lorda, J. Peinado-Onsurbe, et al. 2002. TNFalpha expression of subcutaneous adipose tissue in obese and morbid obese females: Relationship to adipocyte LPL activity and leptin synthesis. Int J Obes Relat Metab Disord 26:652-658.
    • (2002) Int J Obes Relat Metab Disord , vol.26 , pp. 652-658
    • Bullo, M.1    Garcia-Lorda, P.2    Peinado-Onsurbe, J.3
  • 82
    • 0026669452 scopus 로고
    • Interleukin 6 reduces lipoprotein lipase activity in adipose tissue of mice in vivo and in 3T3-L1 adipocytes: A possible role for interleukin 6 in cancer cachexia
    • Greenberg, A.S., R.P. Nordan, J. McIntosh, J.C. Calvo, R.O. Scow, and D. Jablons. 1992. Interleukin 6 reduces lipoprotein lipase activity in adipose tissue of mice in vivo and in 3T3-L1 adipocytes: A possible role for interleukin 6 in cancer cachexia. Cancer Res 52:4113-4116.
    • (1992) Cancer Res , vol.52 , pp. 4113-4116
    • Greenberg, A.S.1    Nordan, R.P.2    McIntosh, J.3    Calvo, J.C.4    Scow, R.O.5    Jablons, D.6
  • 83
    • 0036156874 scopus 로고    scopus 로고
    • Inhibition of lipopolysaccharide-induced apoptosis by cilostazol in human umbilical vein endothelial cells
    • Kim, K.Y., H.K. Shin, J.M. Choi, and K.W. Hong. 2002. Inhibition of lipopolysaccharide-induced apoptosis by cilostazol in human umbilical vein endothelial cells. J Pharmacol Exp Ther 300: 709-715.
    • (2002) J Pharmacol Exp Ther , vol.300 , pp. 709-715
    • Kim, K.Y.1    Shin, H.K.2    Choi, J.M.3    Hong, K.W.4
  • 84
    • 0027494487 scopus 로고
    • Effect of cilostazol on triglyceride metabolism in rats
    • Maeda, E., G. Yoshino, K. Nagata, et al. 1993. Effect of cilostazol on triglyceride metabolism in rats. Curr Ther Res 54:420-424.
    • (1993) Curr Ther Res , vol.54 , pp. 420-424
    • Maeda, E.1    Yoshino, G.2    Nagata, K.3
  • 85
    • 0344443260 scopus 로고    scopus 로고
    • Cilostazol reduces brain lesion induced by focal cerebral ischemia in rats-an MRI study
    • Lee, J.H., Y.K. Lee, M. Ishikawa, et al. 2003. Cilostazol reduces brain lesion induced by focal cerebral ischemia in rats-an MRI study. Brain Res 994:91-98.
    • (2003) Brain Res , vol.994 , pp. 91-98
    • Lee, J.H.1    Lee, Y.K.2    Ishikawa, M.3
  • 86
    • 1342302121 scopus 로고    scopus 로고
    • Cilostazol prevents focal cerebral ischemic injury by enhancing casein kinase 2 phosphorylation and suppression of phosphatase and tensin homolog deleted from chromosome 10 phosphorylation in rats
    • Lee, J.H., K.Y. Kim, Y.K. Lee, et al. 2004. Cilostazol prevents focal cerebral ischemic injury by enhancing casein kinase 2 phosphorylation and suppression of phosphatase and tensin homolog deleted from chromosome 10 phosphorylation in rats. J Pharmacol Exp Ther 308:896-903.
    • (2004) J Pharmacol Exp Ther , vol.308 , pp. 896-903
    • Lee, J.H.1    Kim, K.Y.2    Lee, Y.K.3
  • 87
    • 0036175952 scopus 로고    scopus 로고
    • Neuroprotective effect of cilostazol against focal cerebral ischemia via antiapoptotic action in rats
    • Choi, J.M., H.K. Shin, K.Y. Kim, J.H. Lee, and K.W. Hong. 2002. Neuroprotective effect of cilostazol against focal cerebral ischemia via antiapoptotic action in rats. J Pharmacol Exp Ther 300:787-793.
    • (2002) J Pharmacol Exp Ther , vol.300 , pp. 787-793
    • Choi, J.M.1    Shin, H.K.2    Kim, K.Y.3    Lee, J.H.4    Hong, K.W.5
  • 88
    • 0034235020 scopus 로고    scopus 로고
    • Cilostazol stroke prevention study: A placebo-controlled double-blind trial for secondary prevention of cerebral infarction
    • Gotoh, F., H. Tohgi, S. Hirai, et al. 2000. Cilostazol stroke prevention study: A placebo-controlled double-blind trial for secondary prevention of cerebral infarction. J Stroke and Carebrovasc Dis 9:147-157.
    • (2000) J Stroke and Carebrovasc Dis , vol.9 , pp. 147-157
    • Gotoh, F.1    Tohgi, H.2    Hirai, S.3
  • 90
    • 0021836695 scopus 로고
    • Thermographic evaluation of the hemodynamic effect of the antithrombotic drug cilostazol in peripheral arterial occlusion
    • Ohashi, S., M. Iwatani, Y. Hyakuna, and Y. Morioka. 1985. Thermographic evaluation of the hemodynamic effect of the antithrombotic drug cilostazol in peripheral arterial occlusion. Arzneimittelforschung 35:1203-1208.
    • (1985) Arzneimittelforschung , vol.35 , pp. 1203-1208
    • Ohashi, S.1    Iwatani, M.2    Hyakuna, Y.3    Morioka, Y.4
  • 92
    • 0032544181 scopus 로고    scopus 로고
    • Cilostazol has beneficial effects in treatment of intermittent claudication: Results from a multicenter, randomized, prospective, double-blind trial
    • Dawson, D.L., B.S. Cutler, M.H. Meissner, and D.E.J. Strandness. 1998. Cilostazol has beneficial effects in treatment of intermittent claudication: Results from a multicenter, randomized, prospective, double-blind trial. Circulation 98:678-686.
    • (1998) Circulation , vol.98 , pp. 678-686
    • Dawson, D.L.1    Cutler, B.S.2    Meissner, M.H.3    Strandness, D.E.J.4
  • 93
    • 0031929569 scopus 로고    scopus 로고
    • Effect of cilostazol on walking distances in patients with intermittent claudication caused by peripheral vascular disease
    • Money, S.R., J.A. Herd, J.L. Isaacsohn, et al. 1998. Effect of cilostazol on walking distances in patients with intermittent claudication caused by peripheral vascular disease. J Vasc Surg 27: 267-274.
    • (1998) J Vasc Surg , vol.27 , pp. 267-274
    • Money, S.R.1    Herd, J.A.2    Isaacsohn, J.L.3
  • 94
    • 0033610236 scopus 로고    scopus 로고
    • A new pharmacological treatment for intermittent claudication: Results of a randomized, multicenter trial
    • Beebe, H.G., D.L. Dawson, B.S. Cutler, et al. 1999. A new pharmacological treatment for intermittent claudication: Results of a randomized, multicenter trial. Arch Intern Med 159: 2041-2050.
    • (1999) Arch Intern Med , vol.159 , pp. 2041-2050
    • Beebe, H.G.1    Dawson, D.L.2    Cutler, B.S.3
  • 95
    • 0033754497 scopus 로고    scopus 로고
    • A comparison of cilostazol and pentoxifylline for treating intermittent claudication
    • Dawson, D.L., B.S. Cutler, W.R. Hiatt, et al. 2000. A comparison of cilostazol and pentoxifylline for treating intermittent claudication. Am J Med 109:523-530.
    • (2000) Am J Med , vol.109 , pp. 523-530
    • Dawson, D.L.1    Cutler, B.S.2    Hiatt, W.R.3
  • 96
    • 0030590746 scopus 로고    scopus 로고
    • A randomised, blinded, trial of clopidogrel versus aspirin in patients at risk of ischaemic events (CAPRIE). CAPRIE Steering Committee
    • CAPRIE Steering Committee. 1996. A randomised, blinded, trial of clopidogrel versus aspirin in patients at risk of ischaemic events (CAPRIE). CAPRIE Steering Committee. Lancet 348:1329-1339.
    • (1996) Lancet , vol.348 , pp. 1329-1339
  • 97
    • 0025168189 scopus 로고
    • European Stroke Prevention Study. ESPS Group. 1990. Stroke 21:1122-1130.
    • (1990) Stroke , vol.21 , pp. 1122-1130
  • 98
    • 0030297319 scopus 로고    scopus 로고
    • European Stroke Prevention Study. 2. Dipyridamole and acetylsalicylic acid in the secondary prevention of stroke
    • Diener, H.C., L. Cunha, C. Forbes, J. Sivenius, P. Smets, and A. Lowenthal. 1996. European Stroke Prevention Study. 2. Dipyridamole and acetylsalicylic acid in the secondary prevention of stroke. J Neurol Sci 143:1-13.
    • (1996) J Neurol Sci , vol.143 , pp. 1-13
    • Diener, H.C.1    Cunha, L.2    Forbes, C.3    Sivenius, J.4    Smets, P.5    Lowenthal, A.6
  • 99
    • 0029841805 scopus 로고    scopus 로고
    • Brain SPECT with dipyridamole stress to evaluate cerebral blood flow reserve in carotid artery disease
    • Hwang, T.L., A. Saenz, J.J. Farrell, and W.L. Brannon. 1996. Brain SPECT with dipyridamole stress to evaluate cerebral blood flow reserve in carotid artery disease. J Nucl Med 37: 1595-1599.
    • (1996) J Nucl Med , vol.37 , pp. 1595-1599
    • Hwang, T.L.1    Saenz, A.2    Farrell, J.J.3    Brannon, W.L.4
  • 100
    • 0032797222 scopus 로고    scopus 로고
    • Effect of intravenous dipyridamole on cerebral blood flow in humans. A PET study
    • Ito, H., T. Kinoshita, Y. Tamura, I. Yokoyama, and H. Iida. 1999. Effect of intravenous dipyridamole on cerebral blood flow in humans. A PET study. Stroke 30:1616-1620.
    • (1999) Stroke , vol.30 , pp. 1616-1620
    • Ito, H.1    Kinoshita, T.2    Tamura, Y.3    Yokoyama, I.4    Iida, H.5
  • 101
    • 0030978007 scopus 로고    scopus 로고
    • Use of cilostazol, a novel antiplatelet agent, in a post-Palmaz-Schatz stenting regimen
    • Ochiai, M., T. Isshiki, S. Takeshita, et al. 1997. Use of cilostazol, a novel antiplatelet agent, in a post-Palmaz-Schatz stenting regimen. Am J Cardiol 79:1471-1474.
    • (1997) Am J Cardiol , vol.79 , pp. 1471-1474
    • Ochiai, M.1    Isshiki, T.2    Takeshita, S.3
  • 102
  • 103
    • 0032855354 scopus 로고    scopus 로고
    • Comparison of cilostazol versus ticlopidine therapy after stent implantation
    • Park, S.W., C.W. Lee, H.S. Kim, et al. 1999. Comparison of cilostazol versus ticlopidine therapy after stent implantation. Am J Cardiol 84:511-514.
    • (1999) Am J Cardiol , vol.84 , pp. 511-514
    • Park, S.W.1    Lee, C.W.2    Kim, H.S.3
  • 104
    • 3142781372 scopus 로고    scopus 로고
    • Comparison of cilostazol and ticlopidine for one-month effectiveness and safety after elective coronary stenting
    • Hashiguchi, M., K. Ohno, R. Nakazawa, S. Kishino, M. Mochizuki, and T. Shiga. 2004. Comparison of cilostazol and ticlopidine for one-month effectiveness and safety after elective coronary stenting. Cardiovasc Drugs Ther 18:211-217.
    • (2004) Cardiovasc Drugs Ther , vol.18 , pp. 211-217
    • Hashiguchi, M.1    Ohno, K.2    Nakazawa, R.3    Kishino, S.4    Mochizuki, M.5    Shiga, T.6
  • 105
    • 10644264277 scopus 로고    scopus 로고
    • Cilostazol, clopidogrel or ticlopidine to prevent sub-acute stent thrombosis: A meta-analysis of randomized trials
    • Schleinitz, M.D., I. Olkin, and P.A. Heidenreich. 2004. Cilostazol, clopidogrel or ticlopidine to prevent sub-acute stent thrombosis: A meta-analysis of randomized trials. Am Heart J 148: 990-997.
    • (2004) Am Heart J , vol.148 , pp. 990-997
    • Schleinitz, M.D.1    Olkin, I.2    Heidenreich, P.A.3
  • 106
    • 3142628209 scopus 로고    scopus 로고
    • Effects of antiplatelet agents on subacute thrombosis and restenosis after successful coronary stenting: A randomized comparison of ticlopidine and cilostazol
    • Sekiguchi, M., H. Hoshizaki, H. Adachi, S. Ohshima, K. Taniguchi, and M. Kurabayashi. 2004. Effects of antiplatelet agents on subacute thrombosis and restenosis after successful coronary stenting: A randomized comparison of ticlopidine and cilostazol. Circ J 68:610-614.
    • (2004) Circ J , vol.68 , pp. 610-614
    • Sekiguchi, M.1    Hoshizaki, H.2    Adachi, H.3    Ohshima, S.4    Taniguchi, K.5    Kurabayashi, M.6
  • 107
    • 15244356877 scopus 로고    scopus 로고
    • Comparison of cilostazol and clopidogrel after successful coronary stenting
    • Lee, S.W., S.W. Park, M.K. Hong, et al. 2005. Comparison of cilostazol and clopidogrel after successful coronary stenting. Am J Cardiol 95:859-862.
    • (2005) Am J Cardiol , vol.95 , pp. 859-862
    • Lee, S.W.1    Park, S.W.2    Hong, M.K.3
  • 108
    • 0037452233 scopus 로고    scopus 로고
    • Drug-eluting stents in vascular intervention
    • Fattori, R., and T. Piva. 2003. Drug-eluting stents in vascular intervention. Lancet 361:247-249.
    • (2003) Lancet , vol.361 , pp. 247-249
    • Fattori, R.1    Piva, T.2
  • 109
    • 8244220339 scopus 로고    scopus 로고
    • Effect of cilostazol in preventing restenosis after percutaneous transluminal coronary angioplasty
    • Take, S., M. Matsutani, H. Ueda, et al. 1997. Effect of cilostazol in preventing restenosis after percutaneous transluminal coronary angioplasty. Am J Cardiol 79:1097-1099.
    • (1997) Am J Cardiol , vol.79 , pp. 1097-1099
    • Take, S.1    Matsutani, M.2    Ueda, H.3
  • 110
    • 9844255579 scopus 로고    scopus 로고
    • A randomized trial of aspirin versus cilostazol therapy after successful coronary stent implantation
    • Kunishima, T., H. Musha, F. Eto, et al. 1997. A randomized trial of aspirin versus cilostazol therapy after successful coronary stent implantation. Clin Ther 19:1058-1066.
    • (1997) Clin Ther , vol.19 , pp. 1058-1066
    • Kunishima, T.1    Musha, H.2    Eto, F.3
  • 111
    • 0032527933 scopus 로고    scopus 로고
    • Effects ofprobucol and cilostazol alone and in combination on frequency of poststenting restenosis
    • Sekiya, M., J. Funada, K. Watanabe, M. Miyagawa, and H. Akutsu. 1998. Effects ofprobucol and cilostazol alone and in combination on frequency of poststenting restenosis. Am J Cardiol 82: 144-147.
    • (1998) Am J Cardiol , vol.82 , pp. 144-147
    • Sekiya, M.1    Funada, J.2    Watanabe, K.3    Miyagawa, M.4    Akutsu, H.5
  • 112
    • 0031875007 scopus 로고    scopus 로고
    • Effects ofcilostazol on late lumen loss after Palmaz-Schatz stent implantation
    • Yamasaki, M., K. Hara, Y. Ikari, et al. 1998. Effects ofcilostazol on late lumen loss after Palmaz-Schatz stent implantation. Cathet Cardiovasc Diagn 44:387-391.
    • (1998) Cathet Cardiovasc Diagn , vol.44 , pp. 387-391
    • Yamasaki, M.1    Hara, K.2    Ikari, Y.3
  • 113
    • 0033529402 scopus 로고    scopus 로고
    • Impact of cilostazol on restenosis after percutaneous coronary balloon angioplasty
    • Tsuchikane, E., A. Fukuhara, T. Kobayashi, et al. 1999. Impact of cilostazol on restenosis after percutaneous coronary balloon angioplasty. Circulation 100:21-26.
    • (1999) Circulation , vol.100 , pp. 21-26
    • Tsuchikane, E.1    Fukuhara, A.2    Kobayashi, T.3
  • 114
    • 0000409396 scopus 로고    scopus 로고
    • The potential of cilostazol in interventional cardiology
    • Tsuchikane, E., T. Kobayashi, and N. Awata. 2000. The potential of cilostazol in interventional cardiology. Curr Interv Cardiol Rep 2:143-148.
    • (2000) Curr Interv Cardiol Rep , vol.2 , pp. 143-148
    • Tsuchikane, E.1    Kobayashi, T.2    Awata, N.3
  • 115
    • 0032752190 scopus 로고    scopus 로고
    • Impact of cilostazol on clinical and angiographic outcome after primary stenting for acute myocardial infarction
    • Ochiai, M., K. Eto, S. Takeshita, et al. 1999. Impact of cilostazol on clinical and angiographic outcome after primary stenting for acute myocardial infarction. Am J Cardiol 84:1074-1076.
    • (1999) Am J Cardiol , vol.84 , pp. 1074-1076
    • Ochiai, M.1    Eto, K.2    Takeshita, S.3
  • 116
    • 0034989542 scopus 로고    scopus 로고
    • Effect of cilostazol on restenosis after coronary angioplasty and stenting in comparison to conventional coronary artery stenting with ticlopidine
    • Tanabe, Y., E. Ito, I. Nakagawa, and K. Suzuki. 2001. Effect of cilostazol on restenosis after coronary angioplasty and stenting in comparison to conventional coronary artery stenting with ticlopidine. Int J Cardiol 78:285-291.
    • (2001) Int J Cardiol , vol.78 , pp. 285-291
    • Tanabe, Y.1    Ito, E.2    Nakagawa, I.3    Suzuki, K.4
  • 117
    • 0033039357 scopus 로고    scopus 로고
    • Effect of antithrombotic agents on the patency of PTFE-covered stents in the inferior vena cava: An experimental study
    • Makutani, S., K. Kichikawa, H. Uchida, et al. 1999. Effect of antithrombotic agents on the patency of PTFE-covered stents in the inferior vena cava: An experimental study. Cardiovasc Interv Radiol 22:232-238.
    • (1999) Cardiovasc Interv Radiol , vol.22 , pp. 232-238
    • Makutani, S.1    Kichikawa, K.2    Uchida, H.3
  • 118
    • 0141867652 scopus 로고    scopus 로고
    • Rationale and design of the randomized, multicenter, cilostazol for RESTenosis (CREST) trial
    • Douglas, J.S., W.S. Weintraub, and D. Holmes. 2003. Rationale and design of the randomized, multicenter, cilostazol for RESTenosis (CREST) trial. Clin Cardiol 26:451-454.
    • (2003) Clin Cardiol , vol.26 , pp. 451-454
    • Douglas, J.S.1    Weintraub, W.S.2    Holmes, D.3
  • 119
    • 27844463244 scopus 로고    scopus 로고
    • Coronary stent restenosis in patients treated with cilostazol
    • Douglas, J.S., Jr., D.R. Holmes, Jr., D.J. Kereiakes, et al. 2005. Coronary stent restenosis in patients treated with cilostazol. Circulation 112:2826-2832.
    • (2005) Circulation , vol.112 , pp. 2826-2832
    • Douglas, J.S.1    Holmes, D.R.2    Kereiakes, D.J.3
  • 120
    • 20844433690 scopus 로고    scopus 로고
    • Effect of cilostazol, a phosphodiesterase inhibitor, on carotid IMT in Japanese type 2 diabetic patients
    • Mitsuhashi, N., Y. Tanaka, S. Kubo, et al. 2004. Effect of cilostazol, a phosphodiesterase inhibitor, on carotid IMT in Japanese type 2 diabetic patients. Endocr J 51:545-550.
    • (2004) Endocr J , vol.51 , pp. 545-550
    • Mitsuhashi, N.1    Tanaka, Y.2    Kubo, S.3
  • 121
    • 0242488838 scopus 로고    scopus 로고
    • Effects of cilostazol in patients with Raynaud's syndrome
    • Rajagopalan, S., D. Pfenninger, E. Somers, et al. 2003. Effects of cilostazol in patients with Raynaud's syndrome. Am J Cardiol 92:1310-1315.
    • (2003) Am J Cardiol , vol.92 , pp. 1310-1315
    • Rajagopalan, S.1    Pfenninger, D.2    Somers, E.3
  • 122
    • 0038199678 scopus 로고    scopus 로고
    • Effect of cilostazol on vasomotor reactivity in patients with vasospastic angina pectoris
    • Watanabe, K., S. Ikeda, J. Komatsu, et al. 2003. Effect of cilostazol on vasomotor reactivity in patients with vasospastic angina pectoris. Am J Cardiol 92:21-25.
    • (2003) Am J Cardiol , vol.92 , pp. 21-25
    • Watanabe, K.1    Ikeda, S.2    Komatsu, J.3


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