메뉴 건너뛰기




Volumn 36, Issue , 1996, Pages 403-427

Cyclic nucleotide phosphodiesterases and vascular smooth muscle

Author keywords

asthma; cyclic nucleotide metabolism; PDE isozymes and inhibitors; pulmonary hypertension; vascular disease

Indexed keywords

1 (3 CHLOROANILINO) 4 PHENYLPHTHALAZINE; 1 [6 CHLORO 4 (3,4 METHYLENEDIOXYBENZYLAMINO) 2 QUINAZOLINYL] 4 PIPERIDINECARBOXYLIC ACID; 1,3 DIHYDRO 5 (1,4,5,6 TETRAHYDRO 6 OXO 3 PYRIDAZINYL) 2H INDOL 2 ONE; 4 (3 BUTOXY 4 METHOXYBENZYL) 2 IMIDAZOLIDINONE; 4,5 DIHYDRO 6 [4 (1H IMIDAZOL 1 YL)PHENYL] 5 METHYL 3(2H) PYRIDAZINONE; AMRINONE; CILOSTAMIDE; CILOSTAZOL; CIPROSTENE; CYCLIC NUCLEOTIDE PHOSPHODIESTERASE; DIPYRIDAMOLE; ENOXIMONE; IMAZODAN; INDOLIDAN; ISOENZYME; ISOMAZOLE; LY 186232; LY 195114; LY 197055; LY 197096; LY 198419; PHOSPHODIESTERASE INHIBITOR; PIROXIMONE; ROLIPRAM; SIGUAZODAN; UNCLASSIFIED DRUG; VINPOCETINE; ZAPRINAST;

EID: 0029942933     PISSN: 00664251     EISSN: None     Source Type: Book Series    
DOI: 10.1146/annurev.pa.36.040196.002155     Document Type: Review
Times cited : (187)

References (90)
  • 1
    • 0017274843 scopus 로고
    • Inhibitors and activators of cyclic nucleotide phosphodiesterase
    • Chasin M, Harris DN. 1976. Inhibitors and activators of cyclic nucleotide phosphodiesterase. Adv. Cycl Nucl. Res. 7: 225-64
    • (1976) Adv. Cycl Nucl. Res. , vol.7 , pp. 225-264
    • Chasin, M.1    Harris, D.N.2
  • 2
    • 0015454191 scopus 로고
    • Structure-activity relationships for inhibitors of phosphodiesterase from erythrocytes and other tissues
    • Sheppard H, Wiggan G, Tsien WH. 1972. Structure-activity relationships for inhibitors of phosphodiesterase from erythrocytes and other tissues. Adv. Cycl. Nucl Res. 1:103-12
    • (1972) Adv. Cycl. Nucl Res. , vol.1 , pp. 103-112
    • Sheppard, H.1    Wiggan, G.2    Tsien, W.H.3
  • 3
    • 0028136159 scopus 로고
    • Multiple cyclic nucleotide phosphodiesterases
    • Beavo JA, Conti M, Heaslip RJ. 1994. Multiple cyclic nucleotide phosphodiesterases. Mol. Pharmacol. 46:399-405
    • (1994) Mol. Pharmacol. , vol.46 , pp. 399-405
    • Beavo, J.A.1    Conti, M.2    Heaslip, R.J.3
  • 4
    • 0022548645 scopus 로고
    • Selective inhibition of cyclic nucleotide phosphodiesterases of human, bovine and rat aorta
    • Lugnier C, Schoeffter P, Le Bee A, Strouthou E, Stoclet JC. 1986. Selective inhibition of cyclic nucleotide phosphodiesterases of human, bovine and rat aorta. Biochem. Pharmacol. 35:1743-51
    • (1986) Biochem. Pharmacol. , vol.35 , pp. 1743-1751
    • Lugnier, C.1    Schoeffter, P.2    Le Bee, A.3    Strouthou, E.4    Stoclet, J.C.5
  • 5
    • 0021295772 scopus 로고
    • Selective inhibitors of three forms of cyclic nucleotide phosphodiesterase-basic and potential clinical applications
    • Hidaka H, Endo T. 1984. Selective inhibitors of three forms of cyclic nucleotide phosphodiesterase-basic and potential clinical applications. Adv. Cycl. Nucleotide Protein Phosphorylation. Res 16.245-76
    • (1984) Adv. Cycl. Nucleotide Protein Phosphorylation. Res , vol.16 , pp. 245-276
    • Hidaka, H.1    Endo, T.2
  • 6
    • 0026538625 scopus 로고
    • Characterization of membrane-bound cyclic nucleotide phosphodiesterases from bovine aortic smooth muscle
    • Ivorra MD, Le Bec A, Lugnier C. 1992. Characterization of membrane-bound cyclic nucleotide phosphodiesterases from bovine aortic smooth muscle. J. Cardiovasc. Pharmacol. 19:532-40
    • (1992) J. Cardiovasc. Pharmacol. , vol.19 , pp. 532-540
    • Ivorra, M.D.1    Le Bec, A.2    Lugnier, C.3
  • 8
    • 0027219855 scopus 로고
    • Isolation of cyclic nucleotide phosphodiesterase isozymes from pig aorta
    • Saeki T, Saito I. 1993. Isolation of cyclic nucleotide phosphodiesterase isozymes from pig aorta. Biochem. Pharmacol. 46:833-39
    • (1993) Biochem. Pharmacol. , vol.46 , pp. 833-839
    • Saeki, T.1    Saito, I.2
  • 9
    • 0024419713 scopus 로고
    • Role of selective cyclic GMP phosphodiesterase inhibition in the myorelaxant actions of M&B 22.948, MY-5445, vinpocetine and 1-methyl-3-isobutyl-8-(methylamino)xanthine
    • Souness JE, Brazdil R, Diocee BK, Jordan R. 1989. Role of selective cyclic GMP phosphodiesterase inhibition in the myorelaxant actions of M&B 22.948, MY-5445, vinpocetine and 1-methyl-3-isobutyl-8-(methylamino)xanthine. Br. J. Pharmacol. 98:725-34
    • (1989) Br. J. Pharmacol. , vol.98 , pp. 725-734
    • Souness, J.E.1    Brazdil, R.2    Diocee, B.K.3    Jordan, R.4
  • 10
    • 0026751097 scopus 로고
    • Cardiovascular cyclic nucleotide phosphodiesterases and their role in regulating cardiovascular function
    • Pagani ED, Buchholz RA, Silver PJ. 1992. Cardiovascular cyclic nucleotide phosphodiesterases and their role in regulating cardiovascular function. Basic Res. Cardiol. 87(Suppl. 1):73-86
    • (1992) Basic Res. Cardiol. , vol.87 , Issue.1 SUPPL. , pp. 73-86
    • Pagani, E.D.1    Buchholz, R.A.2    Silver, P.J.3
  • 11
    • 0023880662 scopus 로고
    • Differential pharmacologic sensitivity of cyclic nucleotide phosphodiesterase isozymes isolated from cardiac muscle, arterial and airway smooth muscle
    • Silver PJ, Hamel LT, Perrone MH, Bentley RG, Bushover CR, Evans DB. 1988. Differential pharmacologic sensitivity of cyclic nucleotide phosphodiesterase isozymes isolated from cardiac muscle, arterial and airway smooth muscle. Eur. J. Pharmacol. 150:85-94
    • (1988) Eur. J. Pharmacol. , vol.150 , pp. 85-94
    • Silver, P.J.1    Hamel, L.T.2    Perrone, M.H.3    Bentley, R.G.4    Bushover, C.R.5    Evans, D.B.6
  • 12
    • 0021337094 scopus 로고
    • Effects of vinpocetine on cyclic nucleotide metabolism in vascular smooth muscle
    • Hagiwara M, Endo T, Hidaka H. 1984. Effects of vinpocetine on cyclic nucleotide metabolism in vascular smooth muscle. Biochem. Pharmacol. 33:453-57
    • (1984) Biochem. Pharmacol. , vol.33 , pp. 453-457
    • Hagiwara, M.1    Endo, T.2    Hidaka, H.3
  • 13
    • 0024454868 scopus 로고
    • Effects of selective inhibitors of cyclic nucleotide phosphodiesterases of rabbit aorta
    • Ann HS, Crim W, Romano M, Sybertz E, Pitts B. 1989. Effects of selective inhibitors of cyclic nucleotide phosphodiesterases of rabbit aorta. Biochem. Pharmacol. 38:3331-39
    • (1989) Biochem. Pharmacol. , vol.38 , pp. 3331-3339
    • Ann, H.S.1    Crim, W.2    Romano, M.3    Sybertz, E.4    Pitts, B.5
  • 14
    • 0019305529 scopus 로고
    • Cyclic nucleotide phosphodiesterase activities from pig coronary arteries
    • Keravis TM, Wells JN, Hardman JG. 1980. Cyclic nucleotide phosphodiesterase activities from pig coronary arteries. Biochim. Biophys. Acta 613: 116-29
    • (1980) Biochim. Biophys. Acta , vol.613 , pp. 116-129
    • Keravis, T.M.1    Wells, J.N.2    Hardman, J.G.3
  • 15
    • 0016758204 scopus 로고
    • Phosphodiesterases from porcine coronary arteries: Inhibition of separated forms by xanthines, papaverine, and cyclic nucleotides
    • Wells JN, Wu YJ, Baird CI, Hardman JG. 1975. Phosphodiesterases from porcine coronary arteries: inhibition of separated forms by xanthines, papaverine, and cyclic nucleotides. Mol. Pharmacol. 11:775-83
    • (1975) Mol. Pharmacol. , vol.11 , pp. 775-783
    • Wells, J.N.1    Wu, Y.J.2    Baird, C.I.3    Hardman, J.G.4
  • 16
    • 0022460551 scopus 로고
    • Multiple molecular forms of cyclic nucleotide phosphodiesterase in cardiac and smooth muscle and in platelets
    • Weishaar RE, Burrows SD, Kobylarz DC, Quade MM, Evans DB. 1986. Multiple molecular forms of cyclic nucleotide phosphodiesterase in cardiac and smooth muscle and in platelets. Biochem. Pharmacol. 35:787-800
    • (1986) Biochem. Pharmacol. , vol.35 , pp. 787-800
    • Weishaar, R.E.1    Burrows, S.D.2    Kobylarz, D.C.3    Quade, M.M.4    Evans, D.B.5
  • 17
    • 0025743760 scopus 로고
    • Characterization of cyclic nucleotide phosphodiesterases from rat mesenteric artery
    • Komas N, Lugnier C, Andriantsitohaina R, Stoclet J-C. 1991. Characterization of cyclic nucleotide phosphodiesterases from rat mesenteric artery. Eur. J. Pharmacol. 208:85-87
    • (1991) Eur. J. Pharmacol. , vol.208 , pp. 85-87
    • Komas, N.1    Lugnier, C.2    Andriantsitohaina, R.3    Stoclet, J.-C.4
  • 18
    • 0026327575 scopus 로고
    • Ca/CaM-stimulated and cGMP-specific phosphodiesterases in vascular and non-vascular tissues
    • Ahn HS, Foster M, Cable M, Pitts BJR, Sybertz EJ. 1991. Ca/CaM-stimulated and cGMP-specific phosphodiesterases in vascular and non-vascular tissues. Adv. Exp. Med. Biol. 308:191-97
    • (1991) Adv. Exp. Med. Biol. , vol.308 , pp. 191-197
    • Ahn, H.S.1    Foster, M.2    Cable, M.3    Pitts, B.J.R.4    Sybertz, E.J.5
  • 19
    • 0028365921 scopus 로고
    • Identification of PDE isozymes in human pulmonary artery and effect of selective PDE inhibitors
    • Rabe KF, Tenor H, Dent G, Schudt C, Nakashima M, Magnussen H 1994. Identification of PDE isozymes in human pulmonary artery and effect of selective PDE inhibitors. Am. J. Physiol. 266:L536-43
    • (1994) Am. J. Physiol. , vol.266
    • Rabe, K.F.1    Tenor, H.2    Dent, G.3    Schudt, C.4    Nakashima, M.5    Magnussen, H.6
  • 20
    • 0025219416 scopus 로고
    • Subclasses of cyclic GMP-specific phosphodiesterase and their role in regulating the effects of atrial natriuretic factor
    • Weishaar RE, Kobylarz-Singer DC, Keiser J, Haleen SJ, Major TC, Rapundalo S, et al. 1990. Subclasses of cyclic GMP-specific phosphodiesterase and their role in regulating the effects of atrial natriuretic factor. Hypertension 15:528-40
    • (1990) Hypertension , vol.15 , pp. 528-540
    • Weishaar, R.E.1    Kobylarz-Singer, D.C.2    Keiser, J.3    Haleen, S.J.4    Major, T.C.5    Rapundalo, S.6
  • 21
    • 0021908888 scopus 로고
    • Differences in the association of calmodulin with cyclic nucleotide phosphodiesterase in relaxed and contracted arterial strips
    • Saitoh Y, Hardman JG, Wells JN. 1985. Differences in the association of calmodulin with cyclic nucleotide phosphodiesterase in relaxed and contracted arterial strips. Biochemistry 24:1613-18
    • (1985) Biochemistry , vol.24 , pp. 1613-1618
    • Saitoh, Y.1    Hardman, J.G.2    Wells, J.N.3
  • 22
    • 0023194347 scopus 로고
    • 2+-calmodulin-sensitive phosphodiesterase activity in porcine coronary artery
    • 2+-calmodulin-sensitive phosphodiesterase activity in porcine coronary artery. Biochem. Pharmacol. 36:1819-24
    • (1987) Biochem. Pharmacol. , vol.36 , pp. 1819-1824
    • Miller, J.R.1    Wells, J.N.2
  • 23
    • 0024592426 scopus 로고
    • m) cyclic adenosine monophosphate phosphodiesterase
    • m) cyclic adenosine monophosphate phosphodiesterase. Am. J. Cardiol. 63:2A-8A
    • (1989) Am. J. Cardiol. , vol.63
    • Silver, P.J.1
  • 24
    • 0026056022 scopus 로고
    • Endothelium-dependent and independent relaxation of the rat aorta by cyclic nucleotide phosphodiesterase inhibitors
    • Komas N, Lugnier C, Stoclet J-C. 1991. Endothelium-dependent and independent relaxation of the rat aorta by cyclic nucleotide phosphodiesterase inhibitors. Br. J. Pharmacol. 104:495-503
    • (1991) Br. J. Pharmacol. , vol.104 , pp. 495-503
    • Komas, N.1    Lugnier, C.2    Stoclet, J.-C.3
  • 25
    • 0027527738 scopus 로고
    • Modulation of vascular cyclic nucleotide phosphodiesterases by cyclic GMP: Role in vasodilatation
    • Lugnier C, Komas N. 1993. Modulation of vascular cyclic nucleotide phosphodiesterases by cyclic GMP: role in vasodilatation. Eur. Heart J. 14(Suppl. 1): 141-48
    • (1993) Eur. Heart J. , vol.14 , Issue.1 SUPPL. , pp. 141-148
    • Lugnier, C.1    Komas, N.2
  • 26
    • 0026531771 scopus 로고
    • Purification and properties of the cGMP-inhibited cAMP phosphodiesterase from bovine aortic smooth muscle
    • Rascon A, Lindgren S, Stavenow L, Belfrage P, Andersson K-E, et al. 1992. Purification and properties of the cGMP-inhibited cAMP phosphodiesterase from bovine aortic smooth muscle. Biochim. Bioiphys. Acta 1134:149-56
    • (1992) Biochim. Bioiphys. Acta , vol.1134 , pp. 149-156
    • Rascon, A.1    Lindgren, S.2    Stavenow, L.3    Belfrage, P.4    Andersson, K.-E.5
  • 27
    • 0025866974 scopus 로고
    • Selective inhibition of cGMP-inhibited and cGMP-noninhibited cyclic nucleotide phosphodiesterases and relaxation of rat aorta
    • Lindgren S, Rascon A, Andersson K-E, Manganiello V, Degerman E. 1991. Selective inhibition of cGMP-inhibited and cGMP-noninhibited cyclic nucleotide phosphodiesterases and relaxation of rat aorta. Biochem. Pharmacol. 42: 545-52
    • (1991) Biochem. Pharmacol. , vol.42 , pp. 545-552
    • Lindgren, S.1    Rascon, A.2    Andersson, K.-E.3    Manganiello, V.4    Degerman, E.5
  • 28
    • 0028949423 scopus 로고
    • Distinctive anatomical patterns of gene expression for cGMP-inhibited cyclic nucleotide phosphodiesterases
    • Reinhardt RR, Chin E, Zhou J, Taira M, Murata T, et al. 1995. Distinctive anatomical patterns of gene expression for cGMP-inhibited cyclic nucleotide phosphodiesterases. J. Clin. Invest. 95: 1528-38
    • (1995) J. Clin. Invest. , vol.95 , pp. 1528-1538
    • Reinhardt, R.R.1    Chin, E.2    Zhou, J.3    Taira, M.4    Murata, T.5
  • 29
    • 0023779932 scopus 로고
    • Comparison of cyclic nucleotide phosphodiesterase isoforms from rat heart and bovine aorta
    • Prigent AF, Fougier S, Nemoz G, Anker G, Pacheco H, et al. 1988. Comparison of cyclic nucleotide phosphodiesterase isoforms from rat heart and bovine aorta. Biochem. Pharmacol. 37:3671-81
    • (1988) Biochem. Pharmacol. , vol.37 , pp. 3671-3681
    • Prigent, A.F.1    Fougier, S.2    Nemoz, G.3    Anker, G.4    Pacheco, H.5
  • 30
    • 0026541078 scopus 로고
    • Effect of flosequinan upon isoenzymes of phosphodiesterase from guinea-pig cardiac and vascular smooth muscle
    • Frodsham G, Jones RB. 1992. Effect of flosequinan upon isoenzymes of phosphodiesterase from guinea-pig cardiac and vascular smooth muscle. Eur. J. Pharmacol. 211:383-91
    • (1992) Eur. J. Pharmacol. , vol.211 , pp. 383-391
    • Frodsham, G.1    Jones, R.B.2
  • 31
    • 0024354722 scopus 로고
    • Phosphodiesterase isozyme inhibition and the potentiation by zaprinast of endothelium-derived relaxing factor and guanylate cyclase stimulating agents in vascular smooth muscle
    • Harris AL, Lemp BM, Bentley RG, Perrone MH, Hamel LT, Silver PJ. 1989. Phosphodiesterase isozyme inhibition and the potentiation by zaprinast of endothelium-derived relaxing factor and guanylate cyclase stimulating agents in vascular smooth muscle. J. Pharmacol. Exp. Ther. 249:394-400
    • (1989) J. Pharmacol. Exp. Ther. , vol.249 , pp. 394-400
    • Harris, A.L.1    Lemp, B.M.2    Bentley, R.G.3    Perrone, M.H.4    Hamel, L.T.5    Silver, P.J.6
  • 32
    • 0001622789 scopus 로고
    • Selective inhibitors of three forms of cyclic nucleotide phosphodiesterases
    • Hidaka H, Tanaka T, Itoh H. 1984. Selective inhibitors of three forms of cyclic nucleotide phosphodiesterases. Trends Pharmacol. Sci. 5:237-39
    • (1984) Trends Pharmacol. Sci. , vol.5 , pp. 237-239
    • Hidaka, H.1    Tanaka, T.2    Itoh, H.3
  • 33
    • 0025093163 scopus 로고
    • Effects of isozyme-selective phosphodiesterase inhibitors on rat aorta and human platelets: Smooth muscle tone, platelet aggregation and cAMP levels
    • Lindgren SHS, Andersson TLG, Vinge E, Andersson K-E. 1990. Effects of isozyme-selective phosphodiesterase inhibitors on rat aorta and human platelets: smooth muscle tone, platelet aggregation and cAMP levels. Acta Physiol. Scand. 140:209-19
    • (1990) Acta Physiol. Scand. , vol.140 , pp. 209-219
    • Lindgren, S.H.S.1    Andersson, T.L.G.2    Vinge, E.3    Andersson, K.-E.4
  • 34
    • 0027371943 scopus 로고
    • Reversal of nitroglycerin tolerance in vitro by the cGMP-phosphodiesterase inhibitor zaprinast
    • Meisheri KD, Pagani ED, VanAller GS, O'Connor B, Silver PJ. 1993. Reversal of nitroglycerin tolerance in vitro by the cGMP-phosphodiesterase inhibitor zaprinast. Eur. J. Pharmacol. 243:141-44
    • (1993) Eur. J. Pharmacol. , vol.243 , pp. 141-144
    • Meisheri, K.D.1    Pagani, E.D.2    Vanaller, G.S.3    O'Connor, B.4    Silver, P.J.5
  • 35
    • 0023627880 scopus 로고
    • In vitro vascular relaxation by new inotropic agents: Relationship to phosphodiesterase inhibition and cyclic nucleotides
    • Kauffman RF, Schenck KW, Utterback BG, Crowe VG, Cohen ML. 1987. In vitro vascular relaxation by new inotropic agents: relationship to phosphodiesterase inhibition and cyclic nucleotides. J. Pharmacol. Exp. Ther. 242: 864-72
    • (1987) J. Pharmacol. Exp. Ther. , vol.242 , pp. 864-872
    • Kauffman, R.F.1    Schenck, K.W.2    Utterback, B.G.3    Crowe, V.G.4    Cohen, M.L.5
  • 36
    • 0023944556 scopus 로고
    • Effects of cilostazol, a selective cAMP phosphodiesterase inhibitor on the contraction of vascular smooth muscle
    • Tanaka T, Ishikawa T, Hagiwara M, Onoda K, Itoh H, Hidaka H. 1988. Effects of cilostazol, a selective cAMP phosphodiesterase inhibitor on the contraction of vascular smooth muscle. Pharmacology 36:313-20
    • (1988) Pharmacology , vol.36 , pp. 313-320
    • Tanaka, T.1    Ishikawa, T.2    Hagiwara, M.3    Onoda, K.4    Itoh, H.5    Hidaka, H.6
  • 37
    • 0022458116 scopus 로고
    • Effects of milrinone on contractile responses of guinea pig trachea, lung parenchyma and pulmonary artery
    • Rossig TH, Drazen JM. 1986. Effects of milrinone on contractile responses of guinea pig trachea, lung parenchyma and pulmonary artery. J. Pharmacol. Exp. Ther. 238:874-79
    • (1986) J. Pharmacol. Exp. Ther. , vol.238 , pp. 874-879
    • Rossig, T.H.1    Drazen, J.M.2
  • 39
    • 0024365817 scopus 로고
    • Relaxant effects of the selective phosphodiesterase inhibitors milrinone and OPC 3911 on isolated human mesenteric vessels
    • Lindgren S, Andersson K-E, Belfrage P, Degerman E, Manganiello VC. 1989. Relaxant effects of the selective phosphodiesterase inhibitors milrinone and OPC 3911 on isolated human mesenteric vessels. Pharmacol. Toxicol. 64:440-45
    • (1989) Pharmacol. Toxicol. , vol.64 , pp. 440-445
    • Lindgren, S.1    Andersson, K.-E.2    Belfrage, P.3    Degerman, E.4    Manganiello, V.C.5
  • 41
    • 0026020862 scopus 로고
    • Synergistic actions of nitrovasodilators and isoprenaline on rat aortic smooth muscle
    • Maurice DH, Crankshaw D, Haslam RJ. 1991. Synergistic actions of nitrovasodilators and isoprenaline on rat aortic smooth muscle. Eur. J. Pharmacol. 192: 235-42
    • (1991) Eur. J. Pharmacol. , vol.192 , pp. 235-242
    • Maurice, D.H.1    Crankshaw, D.2    Haslam, R.J.3
  • 42
    • 0026018269 scopus 로고
    • Selective inhibition of cGMP-inhibitable cAMP phosphodiesterase decreases pulmonary vasoreactivity
    • Haynes J, Kithas PA, Taylor AE, Strada SJ. 1991. Selective inhibition of cGMP-inhibitable cAMP phosphodiesterase decreases pulmonary vasoreactivity. Am. J. Physiol. 261:H487-92
    • (1991) Am. J. Physiol. , vol.261
    • Haynes, J.1    Kithas, P.A.2    Taylor, A.E.3    Strada, S.J.4
  • 43
    • 0023803473 scopus 로고
    • Relaxation of vascular and tracheal smooth muscle by cyclic nucleotide analogs that preferentially activate purified cGMP-dependent protein kinase
    • Francis SH, Noblett BD, Todd BW, Wells JN, Corbin JD. 1988. Relaxation of vascular and tracheal smooth muscle by cyclic nucleotide analogs that preferentially activate purified cGMP-dependent protein kinase. Mol Pharmacol. 34:506-17
    • (1988) Mol Pharmacol. , vol.34 , pp. 506-517
    • Francis, S.H.1    Noblett, B.D.2    Todd, B.W.3    Wells, J.N.4    Corbin, J.D.5
  • 44
    • 0024519884 scopus 로고
    • Methylene blue selectively inhibits pulmonary vasodilator responses in cats
    • Hyman AL, Kadowitz PJ, Lippton HL, 1989. Methylene blue selectively inhibits pulmonary vasodilator responses in cats. J. Appl. Physiol. 66:1513-17
    • (1989) J. Appl. Physiol. , vol.66 , pp. 1513-1517
    • Hyman, A.L.1    Kadowitz, P.J.2    Lippton, H.L.3
  • 47
    • 0025967721 scopus 로고
    • Lack of correlation between activation of cyclic AMP-dependent protein kinase and inhibition of contraction of rat vas deferens by cyclic AMP analogs
    • Hei Y, MacDonell KL, McNeil JH, Diamond J. 1991. Lack of correlation between activation of cyclic AMP-dependent protein kinase and inhibition of contraction of rat vas deferens by cyclic AMP analogs. Mol. Pharmacol. 39:233-38
    • (1991) Mol. Pharmacol. , vol.39 , pp. 233-238
    • Hei, Y.1    MacDonell, K.L.2    McNeil, J.H.3    Diamond, J.4
  • 48
    • 0023656803 scopus 로고
    • Role of cyclic AMP- and cyclic GMP-phosphodiesterases in the control of cyclic nucleotide levels and smooth muscle tone in rat isolated aorta
    • Schoeffter P, Lugnier C, Demesy-Waeldele F, Stoclet JC. 1987. Role of cyclic AMP- and cyclic GMP-phosphodiesterases in the control of cyclic nucleotide levels and smooth muscle tone in rat isolated aorta. Biochem. Pharmacol. 36:3965-72
    • (1987) Biochem. Pharmacol. , vol.36 , pp. 3965-3972
    • Schoeffter, P.1    Lugnier, C.2    Demesy-Waeldele, F.3    Stoclet, J.C.4
  • 49
    • 0025215525 scopus 로고
    • Primary sequence of cyclic nucleotide phosphodiesterase isozymes and the design of selective inhibitors
    • Beavo JA, Reifsnyder DH. 1990. Primary sequence of cyclic nucleotide phosphodiesterase isozymes and the design of selective inhibitors. Trends Pharmacol. Sci. 11:150-55
    • (1990) Trends Pharmacol. Sci. , vol.11 , pp. 150-155
    • Beavo, J.A.1    Reifsnyder, D.H.2
  • 50
    • 0025744571 scopus 로고
    • Bronchial vs. cardiovascular activities of selective phosphodiesterase inhibitors in the anesthetized beta-blocked dog
    • Heaslip RJ, Buckley SK, Sickels BD Grimes D. 1991. Bronchial vs. cardiovascular activities of selective phosphodiesterase inhibitors in the anesthetized beta-blocked dog. J. Pharmacol. Exp. Ther. 257:741-47
    • (1991) J. Pharmacol. Exp. Ther. , vol.257 , pp. 741-747
    • Heaslip, R.J.1    Buckley, S.K.2    Sickels, B.D.3    Grimes, D.4
  • 51
  • 52
    • 0027251443 scopus 로고
    • Phosphodiesterase VA inhibitors
    • Murray KJ. 1993. Phosphodiesterase VA inhibitors. Drug News Persp. 6: 150-56
    • (1993) Drug News Persp. , vol.6 , pp. 150-156
    • Murray, K.J.1
  • 53
    • 0022593098 scopus 로고
    • Phosphodiesterase inhibitors induce endothelium-dependent relaxation of rat and rabbit aorta by potentiating the effects of spontaneously released endothelium-derived relaxing factor
    • Martin W, Furchgott RF, Villani GM, Jothianandan D. 1986. Phosphodiesterase inhibitors induce endothelium-dependent relaxation of rat and rabbit aorta by potentiating the effects of spontaneously released endothelium-derived relaxing factor. J. Pharmacol. Exp. Ther. 237:539-47
    • (1986) J. Pharmacol. Exp. Ther. , vol.237 , pp. 539-547
    • Martin, W.1    Furchgott, R.F.2    Villani, G.M.3    Jothianandan, D.4
  • 54
    • 0023145898 scopus 로고
    • Endothelium-dependent modulation of cGMP levels in intrinsic smooth muscle tone in isolated bovine intrapulmonary artery and vein
    • Ignarro LJ, Byrns RE, Wood KS. 1987. Endothelium-dependent modulation of cGMP levels in intrinsic smooth muscle tone in isolated bovine intrapulmonary artery and vein. Circ. Res. 60:82-92
    • (1987) Circ. Res. , vol.60 , pp. 82-92
    • Ignarro, L.J.1    Byrns, R.E.2    Wood, K.S.3
  • 55
    • 0025852157 scopus 로고
    • Relaxant effects of α-human atrial natriuretic peptide on venous smooth muscle
    • Villanueva MM, Nunes JP, Soares-da-Silva P. 1991. Relaxant effects of α-human atrial natriuretic peptide on venous smooth muscle. J. Auton. Pharmacol. 11:139-45
    • (1991) J. Auton. Pharmacol. , vol.11 , pp. 139-145
    • Villanueva, M.M.1    Nunes, J.P.2    Soares-da-Silva, P.3
  • 56
    • 0026718382 scopus 로고
    • In vitro and in vivo interactions of nitrovasodilators and zaprinast, a cGMP-selective phosphodiesterase inhibitor
    • Merkel LA, Rivera LM, Perrone MH, Lappe RW. 1992. In vitro and in vivo interactions of nitrovasodilators and zaprinast, a cGMP-selective phosphodiesterase inhibitor. Eur. J. Pharmacol. 216:29-35
    • (1992) Eur. J. Pharmacol. , vol.216 , pp. 29-35
    • Merkel, L.A.1    Rivera, L.M.2    Perrone, M.H.3    Lappe, R.W.4
  • 57
    • 0024504364 scopus 로고
    • A comparison of vasodilator activity of agents activating cyclic nucleotides with those inhibiting their metabolism in rabbit isolated ear artery
    • Wood LM, Owen DAA. 1989. A comparison of vasodilator activity of agents activating cyclic nucleotides with those inhibiting their metabolism in rabbit isolated ear artery. Br. J. Pharmacol. 96: 718-24
    • (1989) Br. J. Pharmacol. , vol.96 , pp. 718-724
    • Wood, L.M.1    Owen, D.A.A.2
  • 59
    • 0018578644 scopus 로고
    • Evidence for cyclic GMP-mediated relaxant effects of nitro-compounds in coronary smooth muscle
    • Kukovetz WR, Holzmann S, Wurm A, Poch G. 1979. Evidence for cyclic GMP-mediated relaxant effects of nitro-compounds in coronary smooth muscle. Naunyn Schmiedebergs Arch. Pharmacol. 310:129-38
    • (1979) Naunyn Schmiedebergs Arch. Pharmacol. , vol.310 , pp. 129-138
    • Kukovetz, W.R.1    Holzmann, S.2    Wurm, A.3    Poch, G.4
  • 60
    • 0022007431 scopus 로고
    • Effects of dipyridamole on the glyceryl-trinitrate-induced inhibition of coronary artery muscle tone and platelet aggregation in relationship to cyclic nucleotide metabolism
    • Ahlner J, Andersson RGG, Axelsson KL, Bunnfors I, Wallentin L. 1985. Effects of dipyridamole on the glyceryl-trinitrate-induced inhibition of coronary artery muscle tone and platelet aggregation in relationship to cyclic nucleotide metabolism. Arch. Pharmacol. Toxicol. 57:88-95
    • (1985) Arch. Pharmacol. Toxicol. , vol.57 , pp. 88-95
    • Ahlner, J.1    Andersson, R.G.G.2    Axelsson, K.L.3    Bunnfors, I.4    Wallentin, L.5
  • 61
    • 0022460817 scopus 로고
    • Development of tolerance to glyceryl trinitrate in an isolated human peripheral vein and its relation to cyclic GMP metabolism
    • Ahlner J, Andersson RGG, Axelsson KL, Dahlstrom U, Rydell EL. 1986. Development of tolerance to glyceryl trinitrate in an isolated human peripheral vein and its relation to cyclic GMP metabolism. Acta Pharmacol. Toxicol. 59:123-28
    • (1986) Acta Pharmacol. Toxicol. , vol.59 , pp. 123-128
    • Ahlner, J.1    Andersson, R.G.G.2    Axelsson, K.L.3    Dahlstrom, U.4    Rydell, E.L.5
  • 62
    • 0025761873 scopus 로고
    • Effect of nitrate tolerance and dipyridamole on the response to SIN1 in the human isolated saphenous vein
    • Bohyn M, Berkenboom G, Fontaine J. 1991. Effect of nitrate tolerance and dipyridamole on the response to SIN1 in the human isolated saphenous vein. Cardiovasc. Drugs Ther. 5:457-62
    • (1991) Cardiovasc. Drugs Ther. , vol.5 , pp. 457-462
    • Bohyn, M.1    Berkenboom, G.2    Fontaine, J.3
  • 64
    • 0028131402 scopus 로고
    • Effects of a novel, selective and potent phosphodiesterase type V inhibitor, E4021, on myocardial ischemia in guinea pigs
    • Kodama K, Adachi H, Mori N, Saito I. 1994. Effects of a novel, selective and potent phosphodiesterase type V inhibitor, E4021, on myocardial ischemia in guinea pigs. Eur. J. Pharmacol. 263:93-99
    • (1994) Eur. J. Pharmacol. , vol.263 , pp. 93-99
    • Kodama, K.1    Adachi, H.2    Mori, N.3    Saito, I.4
  • 65
    • 0027406998 scopus 로고
    • M&B 22948, a cGMP phosphodiesterase inhibitor, is a pulmonary vasodilator in lambs
    • Braner DAV, Fineman JR, Chang R, Soifer SJ. 1993. M&B 22948, a cGMP phosphodiesterase inhibitor, is a pulmonary vasodilator in lambs. Am. J. Physiol. 264:H252-58
    • (1993) Am. J. Physiol. , vol.264
    • Braner, D.A.V.1    Fineman, J.R.2    Chang, R.3    Soifer, S.J.4
  • 66
    • 0025816915 scopus 로고
    • Hemodynamic basis for the depressor activity of zaprinast, a selective cyclic GMP phosphodiesterase inhibitor
    • Trapani AJ, Smits GJ, McGraw DE, McMahon EG, Blaine EH. 1991. Hemodynamic basis for the depressor activity of zaprinast, a selective cyclic GMP phosphodiesterase inhibitor. J. Pharmacol. Exp. Ther. 258:269-74
    • (1991) J. Pharmacol. Exp. Ther. , vol.258 , pp. 269-274
    • Trapani, A.J.1    Smits, G.J.2    McGraw, D.E.3    McMahon, E.G.4    Blaine, E.H.5
  • 67
    • 0024831468 scopus 로고
    • Depressor and natriuretic effects of M&B 22,948, a guanosine cyclic 3′5′-monophosphate-selective phosphodiesterase inhibitor
    • McMahon EG, Palocno MA, Mehta P, Olins GM. 1989. Depressor and natriuretic effects of M&B 22,948, a guanosine cyclic 3′5′-monophosphate-selective phosphodiesterase inhibitor. J. Pharmacol. Exp. Ther. 251:1000-5
    • (1989) J. Pharmacol. Exp. Ther. , vol.251 , pp. 1000-1005
    • McMahon, E.G.1    Palocno, M.A.2    Mehta, P.3    Olins, G.M.4
  • 69
    • 0025767092 scopus 로고
    • N-Nitro-L-arginine attenuates the accumulation of aortic cyclic GMP and the hypotension produced by zaprinast
    • Dundore RL, Pratt PF, O'Connor B, Buchholz RA, Pagani ED. 1991. N-Nitro-L-arginine attenuates the accumulation of aortic cyclic GMP and the hypotension produced by zaprinast. Eur. J. Pharmacol. 200:83-87
    • (1991) Eur. J. Pharmacol. , vol.200 , pp. 83-87
    • Dundore, R.L.1    Pratt, P.F.2    O'Connor, B.3    Buchholz, R.A.4    Pagani, E.D.5
  • 70
    • 0025281462 scopus 로고
    • Syndromes of accelerated atherosclerosis, role of vascular injury and smooth muscle cell proliferation
    • Ip JH, Fuster V, Badimon L, Badimon J, Taubman MB, Chesebro JH. 1990. Syndromes of accelerated atherosclerosis, role of vascular injury and smooth muscle cell proliferation. J. Am. Coll. Cardiol. 15:1667-87
    • (1990) J. Am. Coll. Cardiol. , vol.15 , pp. 1667-1687
    • Ip, J.H.1    Fuster, V.2    Badimon, L.3    Badimon, J.4    Taubman, M.B.5    Chesebro, J.H.6
  • 72
    • 0024553336 scopus 로고
    • Nitric oxide-generating vasodilators and 8-bromo-cyclic guanosine monophosphate inhibit mitogenesis and proliferation of cultured rat vascular smooth muscle cells
    • Garg UC, Hassid A. 1989. Nitric oxide-generating vasodilators and 8-bromo-cyclic guanosine monophosphate inhibit mitogenesis and proliferation of cultured rat vascular smooth muscle cells. J. Clin. Invest. 83:1774-77
    • (1989) J. Clin. Invest. , vol.83 , pp. 1774-1777
    • Garg, U.C.1    Hassid, A.2
  • 73
    • 0024377230 scopus 로고
    • Antiproliferative action of cyclic GMP-elevating vasodilators in cultured rabbit aortic smooth muscle cells
    • Kariya K, Kawahara Y, Araki S, Fukuzaki H, Takai Y. 1989. Antiproliferative action of cyclic GMP-elevating vasodilators in cultured rabbit aortic smooth muscle cells. Atherosclerosis 80: 143-47
    • (1989) Atherosclerosis , vol.80 , pp. 143-147
    • Kariya, K.1    Kawahara, Y.2    Araki, S.3    Fukuzaki, H.4    Takai, Y.5
  • 74
    • 0024458501 scopus 로고
    • A comparison of cyclic AMP signaling system in rat aortic myocytes in primary culture and aorta
    • Schoeffter P, Lugnier C, Travo C, Stoclet J-C. 1989. A comparison of cyclic AMP signaling system in rat aortic myocytes in primary culture and aorta. Lab. Invest. 61:177-82
    • (1989) Lab. Invest. , vol.61 , pp. 177-182
    • Schoeffter, P.1    Lugnier, C.2    Travo, C.3    Stoclet, J.-C.4
  • 75
    • 0026738156 scopus 로고
    • Inhibition of pig aortic smooth muscle cell DNA synthesis by selective type III and type IV cyclic AMP phosphodiesterase inhibitors
    • Souness JE, Hassall GA, Parrott DP. 1992. Inhibition of pig aortic smooth muscle cell DNA synthesis by selective type III and type IV cyclic AMP phosphodiesterase inhibitors. Biochem. Pharmacol. 44:857-66
    • (1992) Biochem. Pharmacol. , vol.44 , pp. 857-866
    • Souness, J.E.1    Hassall, G.A.2    Parrott, D.P.3
  • 76
    • 0028870331 scopus 로고
    • Role of phosphodiesterase isoenzymes in regulating intracellular cyclic AMP in adenosine-stimulated smooth muscle cells
    • Xiong Y, Westhead EW, Slakey LL. 1995. Role of phosphodiesterase isoenzymes in regulating intracellular cyclic AMP in adenosine-stimulated smooth muscle cells. Biochem. J. 305:627-33
    • (1995) Biochem. J. , vol.305 , pp. 627-633
    • Xiong, Y.1    Westhead, E.W.2    Slakey, L.L.3
  • 77
    • 0028070508 scopus 로고
    • Synergistic interactions between selective pharmacological inhibitors of phosphodiesterase isozyme families PDE III and PDE IV to attenuate proliferation of rat vascular smooth muscle cells
    • Pan X, Arauz E, Krzanowski JJ, Fitzpatrick DF, Poison JB. 1994. Synergistic interactions between selective pharmacological inhibitors of phosphodiesterase isozyme families PDE III and PDE IV to attenuate proliferation of rat vascular smooth muscle cells. Biochem. Pharmacol. 48:827-35
    • (1994) Biochem. Pharmacol. , vol.48 , pp. 827-835
    • Pan, X.1    Arauz, E.2    Krzanowski, J.J.3    Fitzpatrick, D.F.4    Poison, J.B.5
  • 79
    • 0026690069 scopus 로고
    • Effect of cilostazol, a cyclic AMP phosphodiesterase inhibitor, on the proliferation of rat aortic smooth muscle cells in culture
    • Takahashi S, Oida K, Fujiwara R, Maeda H, Hayashi S, et al. 1992. Effect of cilostazol, a cyclic AMP phosphodiesterase inhibitor, on the proliferation of rat aortic smooth muscle cells in culture. J. Cardiovasc. Pharmacol. 20: 900-6
    • (1992) J. Cardiovasc. Pharmacol. , vol.20 , pp. 900-906
    • Takahashi, S.1    Oida, K.2    Fujiwara, R.3    Maeda, H.4    Hayashi, S.5
  • 80
    • 0026080690 scopus 로고
    • U-61,431F, a stable prostacyclin analogue, inhibits the proliferation of bovine vascular smooth muscle cells with little antiproliferative effect on endothelial cells
    • Shirotani M, Yui Y, Hattori R, Kawai C. 1991. U-61,431F, a stable prostacyclin analogue, inhibits the proliferation of bovine vascular smooth muscle cells with little antiproliferative effect on endothelial cells. Prostaglandins 41:97-110
    • (1991) Prostaglandins , vol.41 , pp. 97-110
    • Shirotani, M.1    Yui, Y.2    Hattori, R.3    Kawai, C.4
  • 82
    • 0025868447 scopus 로고
    • Phosphodiesterase inhibitors: New opportunities for the treatment of asthma
    • Torphy TJ, Undem BJ. 1991. Phosphodiesterase inhibitors: new opportunities for the treatment of asthma. Thorax 46:512-23
    • (1991) Thorax , vol.46 , pp. 512-523
    • Torphy, T.J.1    Undem, B.J.2
  • 83
    • 0026008409 scopus 로고
    • Differential modulation of tissue function and therapeutic potential of selective inhibitors of cyclic nucleotide phosphodiesterase isoenzymes
    • Nicholson CD, Challiss RAJ, Shahid M. 1991. Differential modulation of tissue function and therapeutic potential of selective inhibitors of cyclic nucleotide phosphodiesterase isoenzymes. Trends Pharmacol. Sci. 12:19-27
    • (1991) Trends Pharmacol. Sci. , vol.12 , pp. 19-27
    • Nicholson, C.D.1    Challiss, R.A.J.2    Shahid, M.3
  • 84
    • 0025999955 scopus 로고
    • Cyclic nucleotide phosphodiesterases: Pharmacology, biochemistry and function
    • Thompson WJ. 1991. Cyclic nucleotide phosphodiesterases: pharmacology, biochemistry and function. Pharmac. Ther. 51:13-33
    • (1991) Pharmac. Ther. , vol.51 , pp. 13-33
    • Thompson, W.J.1
  • 86
    • 0028574848 scopus 로고
    • Molecular biology of the cyclic AMP-specific cyclic nucleotide phosphodiesterases: A diverse family of regulatory enzymes
    • Bolger GB. 1994. Molecular biology of the cyclic AMP-specific cyclic nucleotide phosphodiesterases: a diverse family of regulatory enzymes. Cell. Signal. 6:851-59
    • (1994) Cell. Signal. , vol.6 , pp. 851-859
    • Bolger, G.B.1
  • 87
    • 0028919741 scopus 로고
    • Regulatory and catalytic domains of platelet cAMP phosphodiesterases: Targets for drug design
    • Sheth SB, Colman RW. 1995. Regulatory and catalytic domains of platelet cAMP phosphodiesterases: targets for drug design. Semin. Hematol. 32:110-19
    • (1995) Semin. Hematol. , vol.32 , pp. 110-119
    • Sheth, S.B.1    Colman, R.W.2
  • 88
    • 0029009878 scopus 로고
    • Recent progress in understanding the hormonal regulation of phosphodiesterases
    • Conti M, Nemoz G, Sette C, Vicini E. 1995. Recent progress in understanding the hormonal regulation of phosphodiesterases. Endocr. Rev. 16:370-89
    • (1995) Endocr. Rev. , vol.16 , pp. 370-389
    • Conti, M.1    Nemoz, G.2    Sette, C.3    Vicini, E.4
  • 89
    • 0026072333 scopus 로고
    • Identification of a nonsense mutation in the rod pnotoreceptor cGMP phosphodiesterase beta-subunit gene of the rd mouse
    • Pittler SJ, Baehr W. 1991. Identification of a nonsense mutation in the rod pnotoreceptor cGMP phosphodiesterase beta-subunit gene of the rd mouse. Proc. Natl. Acad. Sci. USA 88:8322-26
    • (1991) Proc. Natl. Acad. Sci. USA , vol.88 , pp. 8322-8326
    • Pittler, S.J.1    Baehr, W.2
  • 90
    • 0027262347 scopus 로고
    • Irish setter dogs affected with rod/cone dysplasia contain a nonsense mutation in the rod cGMP phodiesterase beta-subunit gene
    • Suber ML, Pittler SJ, Qin N, Wright GC, Holcombe V, et al. 1993. Irish setter dogs affected with rod/cone dysplasia contain a nonsense mutation in the rod cGMP phodiesterase beta-subunit gene. Proc. Natl. Acad. Sci USA 90:3968-72
    • (1993) Proc. Natl. Acad. Sci USA , vol.90 , pp. 3968-3972
    • Suber, M.L.1    Pittler, S.J.2    Qin, N.3    Wright, G.C.4    Holcombe, V.5


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.