Role of hepatocyte growth factor in endothelial regulation: Prevention of high D-glucose-induced endothelial cell death by prostaglandins and phosphodiesterase type 3 inhibitor

Diabetologia

Volumn 40, Issue 9, 1997, Pages 1053-1061

  Morishita, R ^a   Higaki, J ^a   Hayashi, S I ^a   Yo, Y ^a   Aoki, M ^a   Nakamura, S ^a   Moriguchi, A ^a   Matsushita, H ^a   Matsumoto, K ^a   Nakamura, T ^a   Ogihara, T ^a,b  

^a OSAKA UNIVERSITY MEDICAL SCHOOL   (Japan)

^b OSAKA UNIVERSITY   (Japan)

Author keywords

Apoptosis; Atherosclerosis; Diabetes mellitus; Vascular HGF system; Vascular remodelling

Indexed keywords

BERAPROST; CILOSTAZOL; GLUCOSE; PHOSPHODIESTERASE INHIBITOR; PROSTACYCLIN; PROSTAGLANDIN E1; PROSTAGLANDIN E2; RECOMBINANT BASIC FIBROBLAST GROWTH FACTOR; SCATTER FACTOR; VASCULOTROPIN;

APOPTOSIS; ARTICLE; ATHEROSCLEROSIS; CELL DEATH; DIABETES MELLITUS; ENDOTHELIUM CELL; ENDOTHELIUM INJURY; ENZYME ACTIVATION; ENZYME ACTIVITY; HUMAN; HUMAN CELL; HUMAN TISSUE; PRIORITY JOURNAL; PROSTAGLANDIN METABOLISM; VASCULAR DISEASE;

3',5'-CYCLIC-NUCLEOTIDE PHOSPHODIESTERASE; ALPROSTADIL; AORTA; CELL DEATH; CELLS, CULTURED; CULTURE MEDIA, SERUM-FREE; DINOPROSTONE; ENDOTHELIUM, VASCULAR; EPOPROSTENOL; GLUCOSE; HEPATOCYTE GROWTH FACTOR; HUMANS; MUSCLE, SMOOTH, VASCULAR; PHOSPHODIESTERASE INHIBITORS; PROSTAGLANDINS; TETRAZOLES;

EID: 8544241710     PISSN: 0012186X     EISSN: None     Source Type: Journal    
DOI: 10.1007/s001250050787     Document Type: Article

References (49)

1. Tare M, Parkington HC, Coleman HA, Neild TO, Dusting GJ (1990) Hyperpolarization and relaxation of atrial smooth muscle caused by nitric oxide derived from the endothelium. Nature 346: 69-71
2. Suga S, Nakao K, Itoh H, Komatsu Y, Ogawa Y, Hama N, Imura H (1992) Endothelial production of C-type natriuretic peptide and its marked augmentation by transforming growth factor-β. Possible existence of "vascular natriuretic peptide system". J Clin Invest 90: 1145-1149
3. Itoh H, Pratt RE, Dzau VJ (1990) Atrial natriuretic polypeptide inhibits hypertrophy of vascular smooth muscle cells. J Clin Invest 86: 1690-1697
4. Dzau VJ, Gibbons GH (1991) Endothelium and growth factors in vascular remodeling of hypertension. Hypertension 18 [Suppl III]:III-115-III-121
5. Dzau VJ (1993) The role of mechanical and humoral factors in growth regulation of vascular smooth muscle cells and cardiac myocytes. Curr Opin Nephrol Hypertens 2: 27-32
6. Nakamura Y, Morishita R, Nakamura S et al. (1996) A vascular modulator, hepatocyte growth factor, is associated with systolic blood pressure. Hypertension 28: 409-413
7. Nakamura Y, Morishita R, Higaki J et al. (1996) Hepatocyte growth factor (HGF) is a novel member of endothelium-specific growth factors: additive stimulatory effect of HGF with basic fibroblast growth factor, but not vascular endothelial growth factor. J Hypertens 14: 1067-1072
8. Nakamura Y, Morishita R, Higaki J et al. (1995) Expression of local hepatocyte growth factor system in vascular tissues. Biochem Biophys Res Commun 215: 483-488
9. Kainoh M, Nishio S, Nakadate T (1992) Cytoprotective action of beraprost sodium against peroxide-induced damage in vascular endothelial cells. Pharmacology 45: 61-70
10. Koh E, Morimoto S, Jiang B et al. (1993) Effects of beraprost sodium, a stable analogue of prostacyclin, on hyperplasia, hypertrophy and glycosaminoglycan synthesis of rat aortic smooth muscle cells. Artery 20: 242-252
11. Nilsson J, Olsson AG (1984) Prostaglandin E, inhibits DNA synthesis in arterial smooth muscle cells stimulated with platelet-derived growth factor. Atherosclerosis 53: 77-82
12. Beavo JA, Conti M, Heaslip RJ (1994) Multiple cyclic nucleotide phosphodiesterases. Mol Pharmacol 46: 399-405
13. Tani T, Sakurai K, Kimura Y, Ishikawa T, Hidaka H (1992) Pharmacological manipulation of tissue cyclic AMP by inhibitors. Effects of phosphodiesterase inhibitors on the functions of platelets and vascular endothelial cells. Adv Second Messenger Phosphoprotein Res 25: 215-227
14. Tanaka T, Ishikawa T, Hagiwara M, Onoda K, Itoh H, Hidaka H (1988) Effects of cilostazol, a selective cAMP phosphodiesterase inhibitor on the contraction of vascular smooth muscle. Pharmacology 36: 313-320
15. Souness JE, Hassall GA, Parrott DP (1992) Inhibition of pig aortic smooth muscle cell DNA synthesis by selective type III and type IV cyclic AMP phosphodiesterase inhibitors. Biochem Pharmacol 44: 857-866
16. Fujitani K, Kambayashi J, Murata K et al. (1995) Clinical evaluation of combined administration of oral prostacyclin analogue beraprost and phosphodiesterase inhibitor cilostazol. Pharmacol Res 31: 121-125
17. Numano F, Kishi Y, Ashikaga T (1992) Clinical studies of phosphodiesterase inhibitors for cardiovascular disease. Adv Second Messenger Phosphoprotein Res 25: 395-407
18. Uchikawa T, Murakami T, Furukawa H (1992) Effects of the anti-platelet agent cilostazol on peripheral vascular disease in patients with diabetes mellitus. Arzneimittelforschung 42: 322-324
19. Kannel WB, McGee DL (1979) Diabetes and glucose tolerance as risk factors for cardiovascular disease: the Framingham study. Diabetes Care 241: 2035-2038
20. Graier WF, Wascher TC, Lackner L, Toplak H, Krejs GJ, Kukovetz WR (1993) Exposure to elevated D-glucose concentrations modulates vascular endothelial cell vasodilatory response. Diabetes 42: 1497-1505
21. Hsueh WA, Anderson PW (1993) Systemic hypertension and the renin-angiotensin system in diabetic vascular complications. Am J Cardiol 72: 14H-21H
22. Henry RR, Genuth S (1996) Forum one: current recommendations about intensification of metabolic control in non-insulin-dependent diabetes mellitus. Ann Intern Med 124: 175-177
23. Morishita R, Nakamura S, Nakamura Y et al. (1997) Potential role of endothelium-specific growth factor, hepatocyte growth factor, in endothelial damage in diabetes mellitus. Diabetes 46: 138-142
24. Wertheimer SJ, Myers CL, Wallace RW, Parks TP (1992) Intercellular adhesion molecule-1 gene expression in human endothelial cells. J Biol Chem 267: 12030-12035
25. Bonin PD, Leadley RJ, Erickson LA (1993) Growth factor-induced modulation of endothelial-1 binding to human smooth muscle cells. J Cardiovasc Pharmacol 22:8125-5127
26. + : the implication of a protective role of αB-crystallin accumulation in reactive glia. Brain Res 673: 47-52
27. Shirahata S, Watanabe J, Teruya K et al. (1995) E1A and ras oncogenes synergistically enhance recombinant protein production under control of the cytomegalovirus promoter in BHK-21 cells. Biosci Biotech Biochem 59: 345-347
28. Ishiyama M, Shiga M, Sasamoto K, Mizoguchi M, He P (1993) A new sulfonated tetrazolium salt that produces a highly water-soluble formazan dye. Chem Pharm Bull 41: 1118-1122
29. Mosmann T (1983) Rapid colorimetric assay for cellular growth and survival: application to proliferation and cytotoxicity assays. J Immunol Methods 65: 55-63
30. Libby P, O'Brien KV (1983) Culture of quiescent arterial smooth muscle cells in a defined serum-free medium. J Cell Physiol 115: 217-223
31. Lizard G, Deckert V, Duprez L, Moisant M, Gambert P, Lagrost L (1996) Induction of apoptosis in endothelial cells treated with cholesterol oxides. Am J Pathol 148: 1625-1638
32. Haas-Kogan DA, Kogan SC, Levi D, Dazin P, T'ang A, Fung YKT, Israel MA (1995) Inhibition of apoptosis by the retinoblastoma gene product. Embo J 14: 461-472
33. Yamada A, Matsumoto K, Iwanari H et al. (1995) Rapid and sensitive enzyme-linked immunosorbent assay for measurement of HGF in rat and human tissues. Biomed Res 16: 105-114
34. Tsuda H, Iwase T, Matsumoto K et al. (1992) Immunohistochemical localization of hepatocyte growth factor protein in pancreas islet A-cells of man and rats. Jpn J Cancer Res 83: 1262-1266
35. Nakamura T, Hagiya M, Nishizawa T et al. (1989) Molecular cloning and expression of human hepatocyte growth factor. Nature 342: 440-443
36. Seki T, Ihara I, Sugiyama M et al. (1990) Isolation and expression of cDNA for different forms of hepatocyte growth factor from human leukocytes. Biochem Biophys Res Commun 172: 321-327
37. Baumgartner-Parzer SM, Wagner L, Pettermann M, Grillari J, Gessi A, Waldhausl W (1995) High-glucose-triggered apoptosis in cultured endothelial cells. Diabetes 44: 1323-1327
38. Matsumoto K, Nakamura T (1991) Roles of HGF as a pleiotropic factor in organ regeneration. In: Goldberg ID, Rosen EM (eds) Hepatocyte growth factor-scatter factor (HGF-SF) and C-met receptor. Birkhäuser, Basel, pp 225-249
39. Nakamura T (1991) Structure and function of hepatocyte growth factor. Prog Growth Factor Res 3: 67-86
40. Boros P, Miller CM (1995) Hepatocyte growth factor: a multifunctional cytokine. Lancet 345: 293-295
41. Araki S, Shimada Y, Kaji K, Hayashi H (1990) Apoptosis of vascular endothelial cells by fibroblast growth factor deprivation. Biochem Biophys Res Commun 168: 1194-1200
42. Lee SW, Tsou AP, Chan H, Thomas J, Petrie K, Eugui EM, Allison G (1988) Glucocorticoids selectively inhibit the transcription of the interleukin 1β gene and decrease the stability of interleukin 1β mRNA. Proc Natl Acad Sci USA 85: 1204-1208
43. Matsumoto K, Nakamura T (1993) Roles of HGF as a pleiotropic factor in organ regeneration. In: Goldberg ID, Rosen EM (eds) Hepatocyte growth factor-scatter factor (HGF-SF) and C-met receptor. Birkhauser, Basel. 225-249
44. Ponzetto C, Bardelli A, Zhen Z et al. (1994) A multifunctional docking site mediates signaling and transformation by the HGF/SF receptor family. Cell 77: 261-271
45. Rosen EM, Nigam SK, Goldberg ID (1994) Scatter factor and the c-met receptor: a paradigm for mesenchymal/epithelial interaction. J Cell Biol 127: 1783-1787
46. Canley LG, Cantley LC (1995) Signal transduction by the hepatocyte growth factor receptor, c-met. Activation of the phosphatidvlinositol 3-kinase. J Am Soc Nephrol 5: 1872-1881
47. Ridley AJ, Comoglio PM, Hall A (1995) Regulation of scatter factor/hepatocyte growth factor responses by ras, rac and rho in MDCK cells. Mol Cell Biol 15: 1111-1122
48. Takaishi K, Sasaki T, Kato M et al. (1994) Involvement of Rho p21 small GTP-binding protein and its regulation in HGF-induced cell motility. Oncogene 9: 273-279
49. Okajima A, Miyazawa K, Kitamura N (1993) Characterization of the promoter region of the rat hepatocyte-growth-factor/scatter-factor gene. Eur J Biochem 213: 113-119