메뉴 건너뛰기




Volumn , Issue , 2015, Pages 217-231

RNA in cancer vaccine therapy

Author keywords

[No Author keywords available]

Indexed keywords


EID: 85130505379     PISSN: None     EISSN: None     Source Type: Book    
DOI: None     Document Type: Chapter
Times cited : (2)

References (64)
  • 1
    • 0038668196 scopus 로고
    • Antibody formation initiated in vitro. II. Antibody synthesis in x-irradiated recipients of diffusion chambers containing nucleic acid derived from macrophages incubated with antigen
    • Fishman M, Adler FL. Antibody formation initiated in vitro. II. Antibody synthesis in x-irradiated recipients of diffusion chambers containing nucleic acid derived from macrophages incubated with antigen. J Exp Med 1963; 117: 595-602.
    • (1963) J Exp Med , vol.117 , pp. 595-602
    • Fishman, M.1    Adler, F.L.2
  • 2
    • 0014853445 scopus 로고
    • Transfer of tumor immunity with ribonucleic acid
    • Pilch YH, Ramming KP. Transfer of tumor immunity with ribonucleic acid. Cancer 1970; 26: 630-7.
    • (1970) Cancer , vol.26 , pp. 630-637
    • Pilch, Y.H.1    Ramming, K.P.2
  • 3
    • 77949440365 scopus 로고    scopus 로고
    • RNA as performance-enhancers for dendritic cells
    • Boczkowski D, Nair S. RNA as performance-enhancers for dendritic cells. Expert Opin Biol Ther 2010; 10: 563-74.
    • (2010) Expert Opin Biol Ther , vol.10 , pp. 563-574
    • Boczkowski, D.1    Nair, S.2
  • 5
    • 2942559009 scopus 로고    scopus 로고
    • Cancer immunotherapy with mRNA-transfected dendritic cells
    • Gilboa E, Vieweg J. Cancer immunotherapy with mRNA-transfected dendritic cells. Immunol Rev 2004; 199: 251-63.
    • (2004) Immunol Rev , vol.199 , pp. 251-263
    • Gilboa, E.1    Vieweg, J.2
  • 6
    • 39349103969 scopus 로고    scopus 로고
    • Vaccination with messenger RNA (mRNA)
    • Pascolo S. Vaccination with messenger RNA (mRNA). Handb Exp Pharmacol 2008; 183: 221-35.
    • (2008) Handb Exp Pharmacol , vol.183 , pp. 221-235
    • Pascolo, S.1
  • 7
    • 0035412401 scopus 로고    scopus 로고
    • Highly efficient gene delivery by mRNA electroporation in human hematopoietic cells: Superiority to lipofection and passive pulsing of mRNA and to electroporation of plasmid cDNA for tumor antigen loading of dendritic cells
    • Van Tendeloo VF, Ponsaerts P, Lardon F, et al. Highly efficient gene delivery by mRNA electroporation in human hematopoietic cells: superiority to lipofection and passive pulsing of mRNA and to electroporation of plasmid cDNA for tumor antigen loading of dendritic cells. Blood 2001; 98: 49-56.
    • (2001) Blood , vol.98 , pp. 49-56
    • van Tendeloo, V.F.1    Ponsaerts, P.2    Lardon, F.3
  • 8
    • 0034517560 scopus 로고    scopus 로고
    • Human dendritic cells transfected with either RNA or DNA encoding influenza matrix protein M1 differ in their ability to stimulate cytotoxic T lymphocytes
    • Strobel I, Berchtold S, Gotze A, et al. Human dendritic cells transfected with either RNA or DNA encoding influenza matrix protein M1 differ in their ability to stimulate cytotoxic T lymphocytes. Gene Ther 2000; 7: 2028-35.
    • (2000) Gene Ther , vol.7 , pp. 2028-2035
    • Strobel, I.1    Berchtold, S.2    Gotze, A.3
  • 9
    • 0034652624 scopus 로고    scopus 로고
    • Induction of tumor immunity and cytotoxic T lymphocyte responses using dendritic cells transfected with messenger RNA amplified from tumor cells
    • Boczkowski D, Nair SK, Nam JH, Lyerly HK, Gilboa E. Induction of tumor immunity and cytotoxic T lymphocyte responses using dendritic cells transfected with messenger RNA amplified from tumor cells. Cancer Res 2000; 60: 1028-34.
    • (2000) Cancer Res , vol.60 , pp. 1028-1034
    • Boczkowski, D.1    Nair, S.K.2    Nam, J.H.3    Lyerly, H.K.4    Gilboa, E.5
  • 10
    • 0035284901 scopus 로고    scopus 로고
    • Induction of polyclonal prostate cancer-specific CTL using dendritic cells transfected with amplified tumor RNA
    • Heiser A, Maurice MA, Yancey DR, et al. Induction of polyclonal prostate cancer-specific CTL using dendritic cells transfected with amplified tumor RNA. J Immunol 2001; 166: 2953-60.
    • (2001) J Immunol , vol.166 , pp. 2953-2960
    • Heiser, A.1    Maurice, M.A.2    Yancey, D.R.3
  • 11
    • 0037344753 scopus 로고    scopus 로고
    • Delivery of tumor-derived RNA for the induction of cytotoxic T-lymphocytes
    • Grunebach F, Muller MR, Nencioni A, Brossart P. Delivery of tumor-derived RNA for the induction of cytotoxic T-lymphocytes. Gene Ther 2003; 10: 367-74.
    • (2003) Gene Ther , vol.10 , pp. 367-374
    • Grunebach, F.1    Muller, M.R.2    Nencioni, A.3    Brossart, P.4
  • 12
    • 0029839058 scopus 로고    scopus 로고
    • Dendritic cells pulsed with RNA are potent antigenpresenting cells in vitro and in vivo
    • Boczkowski D, Nair SK, Snyder D, Gilboa E. Dendritic cells pulsed with RNA are potent antigenpresenting cells in vitro and in vivo. J Exp Med 1996; 184: 465-72.
    • (1996) J Exp Med , vol.184 , pp. 465-472
    • Boczkowski, D.1    Nair, S.K.2    Snyder, D.3    Gilboa, E.4
  • 13
    • 0031960397 scopus 로고    scopus 로고
    • Induction of primary carcinoembryonic antigen (CEA)-specific cytotoxic T lymphocytes in vitro using human dendritic cells transfected with RNA
    • Nair SK, Boczkowski D, Morse M, et al. Induction of primary carcinoembryonic antigen (CEA)-specific cytotoxic T lymphocytes in vitro using human dendritic cells transfected with RNA. Nat Biotechnol 1998; 16: 364-9.
    • (1998) Nat Biotechnol , vol.16 , pp. 364-369
    • Nair, S.K.1    Boczkowski, D.2    Morse, M.3
  • 14
    • 0035870244 scopus 로고    scopus 로고
    • Human dendritic cells transfected with renal tumor RNA stimulate polyclonal T-cell responses against antigens expressed by primary and metastatic tumors
    • Heiser A, Maurice MA, Yancey DR, et al. Human dendritic cells transfected with renal tumor RNA stimulate polyclonal T-cell responses against antigens expressed by primary and metastatic tumors. Cancer Res 2001; 61: 3388-93.
    • (2001) Cancer Res , vol.61 , pp. 3388-3393
    • Heiser, A.1    Maurice, M.A.2    Yancey, D.R.3
  • 15
    • 0033826798 scopus 로고    scopus 로고
    • Induction of cytotoxic T cell responses and tumor immunity against unrelated tumors using telomerase reverse transcriptase RNA transfected dendritic cells
    • Nair SK, Heiser A, Boczkowski D, et al. Induction of cytotoxic T cell responses and tumor immunity against unrelated tumors using telomerase reverse transcriptase RNA transfected dendritic cells. Nat Med 2000; 6: 1011-17.
    • (2000) Nat Med , vol.6 , pp. 1011-1017
    • Nair, S.K.1    Heiser, A.2    Boczkowski, D.3
  • 16
    • 0038528582 scopus 로고    scopus 로고
    • Generation of cytotoxic responses in mice and human individuals against hematological malignancies using survivin-RNA-transfected dendritic cells
    • Zeis M, Siegel S, Wagner A, et al. Generation of cytotoxic responses in mice and human individuals against hematological malignancies using survivin-RNA-transfected dendritic cells. J Immunol 2003; 170: 5391-7.
    • (2003) J Immunol , vol.170 , pp. 5391-5397
    • Zeis, M.1    Siegel, S.2    Wagner, A.3
  • 17
    • 0043245914 scopus 로고    scopus 로고
    • Synergy between tumor immunotherapy and antiangiogenic therapy
    • Nair S, Boczkowski D, Moeller B, et al. Synergy between tumor immunotherapy and antiangiogenic therapy. Blood 2003; 102: 964-71.
    • (2003) Blood , vol.102 , pp. 964-971
    • Nair, S.1    Boczkowski, D.2    Moeller, B.3
  • 18
    • 28244447726 scopus 로고    scopus 로고
    • Tumor immunotherapy targeting fibroblast activation protein, a product expressed in tumor-associated fibroblasts
    • Lee J, Fassnacht M, Nair S, Boczkowski D, Gilboa E. Tumor immunotherapy targeting fibroblast activation protein, a product expressed in tumor-associated fibroblasts. Cancer Res 2005; 65: 11156-63.
    • (2005) Cancer Res , vol.65 , pp. 11156-11163
    • Lee, J.1    Fassnacht, M.2    Nair, S.3    Boczkowski, D.4    Gilboa, E.5
  • 19
    • 38649110793 scopus 로고    scopus 로고
    • Introduction of functional chimeric E/L-selectin by RNA electroporation to target dendritic cells from blood to lymph nodes
    • Dorrie J, Schaft N, Muller I, et al. Introduction of functional chimeric E/L-selectin by RNA electroporation to target dendritic cells from blood to lymph nodes. Cancer Immunol Immunother 2008; 57: 467-77.
    • (2008) Cancer Immunol Immunother , vol.57 , pp. 467-477
    • Dorrie, J.1    Schaft, N.2    Muller, I.3
  • 20
    • 56449097201 scopus 로고    scopus 로고
    • Type 2 Bias of T cells expanded from the blood of melanoma patients switched to type 1 by IL-12p70 mRNA-transfected dendritic cells
    • Minkis K, Kavanagh DG, Alter G, et al. Type 2 Bias of T cells expanded from the blood of melanoma patients switched to type 1 by IL-12p70 mRNA-transfected dendritic cells. Cancer Res 2008; 68: 9441-50.
    • (2008) Cancer Res , vol.68 , pp. 9441-9450
    • Minkis, K.1    Kavanagh, D.G.2    Alter, G.3
  • 21
    • 45249113920 scopus 로고    scopus 로고
    • Tumor associated antigen and interleukin-12 mRNA transfected dendritic cells enhance effector function of natural killer cells and antigen specific T-cells
    • Bontkes HJ, Kramer D, Ruizendaal JJ, Meijer CJ, Hooijberg E. Tumor associated antigen and interleukin-12 mRNA transfected dendritic cells enhance effector function of natural killer cells and antigen specific T-cells. Clin Immunol 2008; 127: 375-84.
    • (2008) Clin Immunol , vol.127 , pp. 375-384
    • Bontkes, H.J.1    Kramer, D.2    Ruizendaal, J.J.3    Meijer, C.J.4    Hooijberg, E.5
  • 22
    • 55249105461 scopus 로고    scopus 로고
    • Ectopic expression of a truncated CD40L protein from synthetic post-transcriptionally capped RNA in dendritic cells induces high levels of IL-12 secretion
    • Published online 17 October 2008
    • Tcherepanova IY, Adams MD, Feng X, et al. Ectopic expression of a truncated CD40L protein from synthetic post-transcriptionally capped RNA in dendritic cells induces high levels of IL-12 secretion. BMC Mol Biol 2008; 9: 90. Published online 17 October 2008.
    • (2008) BMC Mol Biol , vol.9 , pp. 90
    • Tcherepanova, I.Y.1    Adams, M.D.2    Feng, X.3
  • 23
    • 2442707774 scopus 로고    scopus 로고
    • Induction of human dendritic cell maturation using transfection with RNA encoding a dominant positive toll-like receptor 4
    • Cisco RM, Abdel-Wahab Z, Dannull J, et al. Induction of human dendritic cell maturation using transfection with RNA encoding a dominant positive toll-like receptor 4. J Immunol 2004; 172: 7162-8.
    • (2004) J Immunol , vol.172 , pp. 7162-7168
    • Cisco, R.M.1    Abdel-Wahab, Z.2    Dannull, J.3
  • 24
    • 16244381163 scopus 로고    scopus 로고
    • Cotransfection of DC with TLR4 and MART-1 RNA induces MART-1-specific responses
    • Abdel-Wahab Z, Cisco R, Dannull J, et al. Cotransfection of DC with TLR4 and MART-1 RNA induces MART-1-specific responses. J Surg Res 2005; 124: 264-73.
    • (2005) J Surg Res , vol.124 , pp. 264-273
    • Abdel-Wahab, Z.1    Cisco, R.2    Dannull, J.3
  • 25
    • 44349173032 scopus 로고    scopus 로고
    • Enhancing the T-cell stimulatory capacity of human dendritic cells by co-electroporation with CD40L, CD70 and constitutively active TLR4 encoding mRNA
    • Bonehill A, Tuyaerts S, Van Nuffel AM, et al. Enhancing the T-cell stimulatory capacity of human dendritic cells by co-electroporation with CD40L, CD70 and constitutively active TLR4 encoding mRNA. Mol Ther 2008; 16: 1170-80.
    • (2008) Mol Ther , vol.16 , pp. 1170-1180
    • Bonehill, A.1    Tuyaerts, S.2    van Nuffel, A.M.3
  • 26
    • 17044427679 scopus 로고    scopus 로고
    • Enhancing the immunostimulatory function of dendritic cells by transfection with mRNA encoding OX40 ligand
    • Dannull J, Nair S, SuZ, et al. Enhancing the immunostimulatory function of dendritic cells by transfection with mRNA encoding OX40 ligand. Blood 2005; 105: 3206-13.
    • (2005) Blood , vol.105 , pp. 3206-3213
    • Dannull, J.1    Nair, S.2    Su, Z.3
  • 27
    • 23944454886 scopus 로고    scopus 로고
    • Cotransfection of dendritic cells with RNA coding for HER-2/ neu and 4-1BBL increases the induction of tumor antigen specific cytotoxic T lymphocytes
    • Grunebach F, Kayser K, Weck MM, et al. Cotransfection of dendritic cells with RNA coding for HER-2/ neu and 4-1BBL increases the induction of tumor antigen specific cytotoxic T lymphocytes. Cancer Gene Ther 2005; 12: 749-56.
    • (2005) Cancer Gene Ther , vol.12 , pp. 749-756
    • Grunebach, F.1    Kayser, K.2    Weck, M.M.3
  • 28
    • 70449637946 scopus 로고    scopus 로고
    • Dendritic cells engineered to secrete anti-GITR antibodies are effective adjuvants to dendritic cell-based immunotherapy
    • Boczkowski D, Lee J, Pruitt S, Nair S. Dendritic cells engineered to secrete anti-GITR antibodies are effective adjuvants to dendritic cell-based immunotherapy. Cancer Gene Ther 2009; 16: 900-11.
    • (2009) Cancer Gene Ther , vol.16 , pp. 900-911
    • Boczkowski, D.1    Lee, J.2    Pruitt, S.3    Nair, S.4
  • 29
    • 0035039114 scopus 로고    scopus 로고
    • Development of a dendritic cell (DC)-based vaccine for patients with advanced colorectal cancer
    • Rains N, Cannan RJ, Chen W, Stubbs RS. Development of a dendritic cell (DC)-based vaccine for patients with advanced colorectal cancer. Hepatogastroenterology 2001; 48: 347-51.
    • (2001) Hepatogastroenterology , vol.48 , pp. 347-351
    • Rains, N.1    Cannan, R.J.2    Chen, W.3    Stubbs, R.S.4
  • 30
    • 0036167308 scopus 로고    scopus 로고
    • Autologous dendritic cells transfected with prostate-specific antigen RNA stimulate CTL responses against metastatic prostate tumors
    • Heiser A, Coleman D, Dannull J, et al. Autologous dendritic cells transfected with prostate-specific antigen RNA stimulate CTL responses against metastatic prostate tumors. J Clin Invest 2002; 109: 409-17.
    • (2002) J Clin Invest , vol.109 , pp. 409-417
    • Heiser, A.1    Coleman, D.2    Dannull, J.3
  • 31
    • 0036203164 scopus 로고    scopus 로고
    • Induction of tumor-specific cytotoxic T lymphocytes in cancer patients by autologous tumor RNA-transfected dendritic cells
    • Nair SK, Morse M, Boczkowski D, et al. Induction of tumor-specific cytotoxic T lymphocytes in cancer patients by autologous tumor RNA-transfected dendritic cells. Ann Surg 2002; 235: 540-9.
    • (2002) Ann Surg , vol.235 , pp. 540-549
    • Nair, S.K.1    Morse, M.2    Boczkowski, D.3
  • 32
    • 0344837817 scopus 로고    scopus 로고
    • The feasibility and safety of immunotherapy with dendritic cells loaded with CEA mRNA following neoadjuvant chemoradiotherapy and resection of pancreatic cancer
    • Morse MA, Nair SK, Boczkowski D, et al. The feasibility and safety of immunotherapy with dendritic cells loaded with CEA mRNA following neoadjuvant chemoradiotherapy and resection of pancreatic cancer. IntJ Gastrointest Cancer 2002; 32: 1-6.
    • (2002) IntJ Gastrointest Cancer , vol.32 , pp. 1-6
    • Morse, M.A.1    Nair, S.K.2    Boczkowski, D.3
  • 33
    • 0041857805 scopus 로고    scopus 로고
    • Immunotherapy with autologous, human dendritic cells transfected with carcinoembryonic antigen mRNA
    • Morse MA, Nair SK, Mosca PJ, et al. Immunotherapy with autologous, human dendritic cells transfected with carcinoembryonic antigen mRNA. Cancer Invest 2003; 21: 341-9.
    • (2003) Cancer Invest , vol.21 , pp. 341-349
    • Morse, M.A.1    Nair, S.K.2    Mosca, P.J.3
  • 34
    • 0038066552 scopus 로고    scopus 로고
    • Immunological and clinical responses in metastatic renal cancer patients vaccinated with tumor RNA-transfected dendritic cells
    • Su Z, Dannull J, Heiser A, et al. Immunological and clinical responses in metastatic renal cancer patients vaccinated with tumor RNA-transfected dendritic cells. Cancer Res 2003; 63: 2127-33.
    • (2003) Cancer Res , vol.63 , pp. 2127-2133
    • Su, Z.1    Dannull, J.2    Heiser, A.3
  • 35
    • 4344560470 scopus 로고    scopus 로고
    • Results of a phase 1 study utilizing monocyte-derived dendritic cells pulsed with tumor RNA in children and young adults with brain cancer
    • Caruso DA, Orme LM, Neale AM, et al. Results of a phase 1 study utilizing monocyte-derived dendritic cells pulsed with tumor RNA in children and young adults with brain cancer. Neuro Oncol 2004; 6: 236-46.
    • (2004) Neuro Oncol , vol.6 , pp. 236-246
    • Caruso, D.A.1    Orme, L.M.2    Neale, A.M.3
  • 36
    • 14744280609 scopus 로고    scopus 로고
    • Results of a Phase I study utilizing monocyte-derived dendritic cells pulsed with tumor RNA in children with Stage 4 neuroblastoma
    • Caruso DA, Orme LM, Amor GM, et al. Results of a Phase I study utilizing monocyte-derived dendritic cells pulsed with tumor RNA in children with Stage 4 neuroblastoma. Cancer 2005; 103: 1280-91.
    • (2005) Cancer , vol.103 , pp. 1280-1291
    • Caruso, D.A.1    Orme, L.M.2    Amor, G.M.3
  • 37
    • 30144444279 scopus 로고    scopus 로고
    • Enhancement of vaccine-mediated antitumor immunity in cancer patients after depletion of regulatory T cells
    • Dannull J, Su Z, Rizzieri D, et al. Enhancement of vaccine-mediated antitumor immunity in cancer patients after depletion of regulatory T cells. J Clin Invest 2005; 115: 3623-33.
    • (2005) J Clin Invest , vol.115 , pp. 3623-3633
    • Dannull, J.1    Su, Z.2    Rizzieri, D.3
  • 38
    • 20144364773 scopus 로고    scopus 로고
    • Telomerase mRNA-transfected dendritic cells stimulate antigenspecific CD8+ and CD4+ T cell responses in patients with metastatic prostate cancer
    • Su Z, Dannull J, Yang BK, et al. Telomerase mRNA-transfected dendritic cells stimulate antigenspecific CD8+ and CD4+ T cell responses in patients with metastatic prostate cancer. J Immunol 2005; 174: 3798-807.
    • (2005) J Immunol , vol.174 , pp. 3798-3807
    • Su, Z.1    Dannull, J.2    Yang, B.K.3
  • 39
    • 27144507469 scopus 로고    scopus 로고
    • Immunotherapy with allotumour mRNA-transfected dendritic cells in androgen-resistant prostate cancer patients
    • Mu LJ, Kyte JA, Kvalheim G, et al. Immunotherapy with allotumour mRNA-transfected dendritic cells in androgen-resistant prostate cancer patients. Br J Cancer 2005; 93: 749-56.
    • (2005) Br J Cancer , vol.93 , pp. 749-756
    • Mu, L.J.1    Kyte, J.A.2    Kvalheim, G.3
  • 40
    • 18844388926 scopus 로고    scopus 로고
    • Preclinical full-scale evaluation of dendritic cells transfected with autologous tumor-mRNA for melanoma vaccination
    • Kyte JA, Kvalheim G, Aamdal S, Saeboe-Larssen S, Gaudernack G. Preclinical full-scale evaluation of dendritic cells transfected with autologous tumor-mRNA for melanoma vaccination. Cancer Gene Ther 2005; 12: 579-91.
    • (2005) Cancer Gene Ther , vol.12 , pp. 579-591
    • Kyte, J.A.1    Kvalheim, G.2    Aamdal, S.3    Saeboe-Larssen, S.4    Gaudernack, G.5
  • 41
    • 34247218172 scopus 로고    scopus 로고
    • Vaccination with dendritic cells transfected with mRNA-encoded folate-receptor-alpha for relapsed metastatic ovarian cancer
    • Hernando JJ, Park TW, Fischer HP, et al. Vaccination with dendritic cells transfected with mRNA-encoded folate-receptor-alpha for relapsed metastatic ovarian cancer. Lancet Oncol 2007; 8: 451-4.
    • (2007) Lancet Oncol , vol.8 , pp. 451-454
    • Hernando, J.J.1    Park, T.W.2    Fischer, H.P.3
  • 42
    • 66149186858 scopus 로고    scopus 로고
    • Single-step antigen loading and activation of dendritic cells by mRNA electroporation for the purpose of therapeutic vaccination in melanoma patients
    • Bonehill A, Van Nuffel AM, Corthals J, et al. Single-step antigen loading and activation of dendritic cells by mRNA electroporation for the purpose of therapeutic vaccination in melanoma patients. Clin Cancer Res 2009; 15: 3366-75.
    • (2009) Clin Cancer Res , vol.15 , pp. 3366-3375
    • Bonehill, A.1    van Nuffel, A.M.2    Corthals, J.3
  • 43
    • 66149096672 scopus 로고    scopus 로고
    • In situ expression of tumor antigens by messenger RNA-electroporated dendritic cells in lymph nodes of melanoma patients
    • Schuurhuis DH, Verdijk P, Schreibelt G, et al. In situ expression of tumor antigens by messenger RNA-electroporated dendritic cells in lymph nodes of melanoma patients. Cancer Res 2009; 69: 2927-34.
    • (2009) Cancer Res , vol.69 , pp. 2927-2934
    • Schuurhuis, D.H.1    Verdijk, P.2    Schreibelt, G.3
  • 44
    • 77956384935 scopus 로고    scopus 로고
    • Induction of complete and molecular remissions in acute myeloid leukemia by Wilms' tumor 1 antigen-targeted dendritic cell vaccination
    • Van Tendeloo VF, Van de Velde A, Van Driessche A, et al. Induction of complete and molecular remissions in acute myeloid leukemia by Wilms' tumor 1 antigen-targeted dendritic cell vaccination. Proc Natl Acad Sci USA 2010; 107: 13824-9.
    • (2010) Proc Natl Acad Sci USA , vol.107 , pp. 13824-13829
    • van Tendeloo, V.F.1    van de Velde, A.2    van Driessche, A.3
  • 45
    • 77958527547 scopus 로고    scopus 로고
    • Immunological response after therapeutic vaccination with WT1 mRNA-loaded dendritic cells in end-stage endometrial carcinoma
    • Coosemans A, Wolfl M, Berneman ZN, et al. Immunological response after therapeutic vaccination with WT1 mRNA-loaded dendritic cells in end-stage endometrial carcinoma. Anticancer Res 2010; 30: 3709-14.
    • (2010) Anticancer Res , vol.30 , pp. 3709-3714
    • Coosemans, A.1    Wolfl, M.2    Berneman, Z.N.3
  • 46
    • 33749168691 scopus 로고    scopus 로고
    • Preparing clinical-grade myeloid dendritic cells by electroporation-mediated transfection of in vitro amplified tumor-derived mRNA and safety testing in stage IV malignant melanoma
    • Published online 15 August 2006
    • Markovic SN, Dietz AB, Greiner CW, et al. Preparing clinical-grade myeloid dendritic cells by electroporation-mediated transfection of in vitro amplified tumor-derived mRNA and safety testing in stage IV malignant melanoma. J Transl Med 2006; 4: 35. Published online 15 August 2006.
    • (2006) J Transl Med , vol.4 , pp. 35
    • Markovic, S.N.1    Dietz, A.B.2    Greiner, C.W.3
  • 47
    • 0025231388 scopus 로고
    • Direct gene transfer into mouse muscle in vivo
    • Wolff JA, Malone RW, Williams P, et al. Direct gene transfer into mouse muscle in vivo. Science 1990; 247: 1465-8.
    • (1990) Science , vol.247 , pp. 1465-1468
    • Wolff, J.A.1    Malone, R.W.2    Williams, P.3
  • 48
    • 0034768443 scopus 로고    scopus 로고
    • Synthesis and properties of mRNAs containing the novel "anti-reverse" cap analogs 7-methyl(3'-O-methyl)GpppG and 7-methyl (3'-deoxy)GpppG
    • Stepinski J, Waddell C, Stolarski R, Darzynkiewicz E, Rhoads RE. Synthesis and properties of mRNAs containing the novel "anti-reverse" cap analogs 7-methyl(3'-O-methyl)GpppG and 7-methyl (3'-deoxy)GpppG. RNA 2001; 7: 1486-95.
    • (2001) RNA , vol.7 , pp. 1486-1495
    • Stepinski, J.1    Waddell, C.2    Stolarski, R.3    Darzynkiewicz, E.4    Rhoads, R.E.5
  • 49
    • 30544433619 scopus 로고    scopus 로고
    • Mrna transfection of dendritic cells: Synergistic effect of ARCA mRNA capping with Poly(A) chains in cis and in trans for a high protein expression level
    • Mockey M, Goncalves C, Dupuy FP, et al. mRNA transfection of dendritic cells: synergistic effect of ARCA mRNA capping with Poly(A) chains in cis and in trans for a high protein expression level. Bio-chem Biophys Res Commun 2006; 340: 1062-8.
    • (2006) Bio-chem Biophys Res Commun , vol.340 , pp. 1062-1068
    • Mockey, M.1    Goncalves, C.2    Dupuy, F.P.3
  • 50
    • 77955658245 scopus 로고    scopus 로고
    • Phosphorothioate cap analogs increase stability and translational efficiency of RNA vaccines in immature dendritic cells and induce superior immune responses in vivo
    • Kuhn AN, Diken M, Kreiter S, et al. Phosphorothioate cap analogs increase stability and translational efficiency of RNA vaccines in immature dendritic cells and induce superior immune responses in vivo. Gene Ther 2010; 17: 961-71.
    • (2010) Gene Ther , vol.17 , pp. 961-971
    • Kuhn, A.N.1    Diken, M.2    Kreiter, S.3
  • 51
    • 33845497677 scopus 로고    scopus 로고
    • Modification of antigen-encoding RNA increases stability, translational efficacy, and T-cell stimulatory capacity of dendritic cells
    • Holtkamp S, Kreiter S, Selmi A, et al. Modification of antigen-encoding RNA increases stability, translational efficacy, and T-cell stimulatory capacity of dendritic cells. Blood 2006; 108: 4009-17.
    • (2006) Blood , vol.108 , pp. 4009-4017
    • Holtkamp, S.1    Kreiter, S.2    Selmi, A.3
  • 52
    • 54949112814 scopus 로고    scopus 로고
    • Incorporation of pseudouridine into mRNA yields superior nonimmunogenic vector with increased translational capacity and biological stability
    • Kariko K, Muramatsu H, Welsh FA, et al. Incorporation of pseudouridine into mRNA yields superior nonimmunogenic vector with increased translational capacity and biological stability. Mol Ther 2008; 16: 1833-40.
    • (2008) Mol Ther , vol.16 , pp. 1833-1840
    • Kariko, K.1    Muramatsu, H.2    Welsh, F.A.3
  • 53
    • 0028965192 scopus 로고
    • Characterization of a messenger RNA polynucleotide vaccine vector
    • Conry RM, LoBuglio AF, Wright M, et al. Characterization of a messenger RNA polynucleotide vaccine vector. Cancer Res 1995; 55: 1397-400.
    • (1995) Cancer Res , vol.55 , pp. 1397-1400
    • Conry, R.M.1    LoBuglio, A.F.2    Wright, M.3
  • 54
    • 0033999511 scopus 로고    scopus 로고
    • Induction of anti-tumor immunity with epidermal cells pulsed with tumor-derived RNA or intradermal administration of RNA
    • Granstein RD, Ding W, Ozawa H. Induction of anti-tumor immunity with epidermal cells pulsed with tumor-derived RNA or intradermal administration of RNA. J Invest Dermatol 2000; 114: 632-6.
    • (2000) J Invest Dermatol , vol.114 , pp. 632-636
    • Granstein, R.D.1    Ding, W.2    Ozawa, H.3
  • 55
    • 0033989908 scopus 로고    scopus 로고
    • In vivo application of RNA leads to induction of specific cytotoxic T lymphocytes and antibodies
    • Hoerr I, Obst R, Rammensee HG, Jung G. In vivo application of RNA leads to induction of specific cytotoxic T lymphocytes and antibodies. Eur J Immunol 2000; 30: 1-7.
    • (2000) Eur J Immunol , vol.30 , pp. 1-7
    • Hoerr, I.1    Obst, R.2    Rammensee, H.G.3    Jung, G.4
  • 56
    • 6044228079 scopus 로고    scopus 로고
    • Polarization of immunity induced by direct injection of naked sequence-stabilized mRNA vaccines
    • Carralot JP, Probst J, Hoerr I, et al. Polarization of immunity induced by direct injection of naked sequence-stabilized mRNA vaccines. Cell Mol Life Sci 2004; 61: 2418-24.
    • (2004) Cell Mol Life Sci , vol.61 , pp. 2418-2424
    • Carralot, J.P.1    Probst, J.2    Hoerr, I.3
  • 57
    • 78549283854 scopus 로고    scopus 로고
    • Intranodal vaccination with naked antigen-encoding RNA elicits potent prophylactic and therapeutic antitumoral immunity
    • Kreiter S, Selmi A, Diken M, et al. Intranodal vaccination with naked antigen-encoding RNA elicits potent prophylactic and therapeutic antitumoral immunity. Cancer Res 2010; 70: 9031-40.
    • (2010) Cancer Res , vol.70 , pp. 9031-9040
    • Kreiter, S.1    Selmi, A.2    Diken, M.3
  • 58
    • 27944481229 scopus 로고    scopus 로고
    • Effective induction of anti-melanoma immunity following genetic vaccination with synthetic mRNA coding for the fusion protein EGFP.TRP2
    • Steitz J, Britten CM, Wolfel T, Tuting T. Effective induction of anti-melanoma immunity following genetic vaccination with synthetic mRNA coding for the fusion protein EGFP.TRP2. Cancer Immunol Immunother 2006; 55: 246-53.
    • (2006) Cancer Immunol Immunother , vol.55 , pp. 246-253
    • Steitz, J.1    Britten, C.M.2    Wolfel, T.3    Tuting, T.4
  • 59
    • 33644591595 scopus 로고    scopus 로고
    • Vaccination with mRNAs encoding tumor-associated antigens and granulocyte-macrophage colony-stimulating factor efficiently primes CTL responses, but is insufficient to overcome tolerance to a model tumor/self antigen
    • Hess PR, Boczkowski D, Nair SK, Snyder D, Gilboa E. Vaccination with mRNAs encoding tumor-associated antigens and granulocyte-macrophage colony-stimulating factor efficiently primes CTL responses, but is insufficient to overcome tolerance to a model tumor/self antigen. Cancer Immunol Immunother 2006; 55: 672-83.
    • (2006) Cancer Immunol Immunother , vol.55 , pp. 672-683
    • Hess, P.R.1    Boczkowski, D.2    Nair, S.K.3    Snyder, D.4    Gilboa, E.5
  • 60
    • 1642301553 scopus 로고    scopus 로고
    • Immunostimulating capacities of stabilized RNA molecules
    • Scheel B, Braedel S, Probst J, et al. Immunostimulating capacities of stabilized RNA molecules. Eur J Immunol 2004; 34: 537-47.
    • (2004) Eur J Immunol , vol.34 , pp. 537-547
    • Scheel, B.1    Braedel, S.2    Probst, J.3
  • 61
    • 78650640612 scopus 로고    scopus 로고
    • Messenger RNA-based vaccines with dual activity induce balanced TLR-7 dependent adaptive immune responses and provide antitumor activity
    • Fotin-Mleczek M, Duchardt KM, Lorenz C, et al. Messenger RNA-based vaccines with dual activity induce balanced TLR-7 dependent adaptive immune responses and provide antitumor activity. J Immunother 2011; 34: 1-15.
    • (2011) J Immunother , vol.34 , pp. 1-15
    • Fotin-Mleczek, M.1    Duchardt, K.M.2    Lorenz, C.3
  • 62
    • 44949195901 scopus 로고    scopus 로고
    • Results of the first phase I/II clinical vaccination trial with direct injection of mRNA
    • Weide B, Carralot JP, Reese A, et al. Results of the first phase I/II clinical vaccination trial with direct injection of mRNA. J Immunother 2008; 31: 180-8.
    • (2008) J Immunother , vol.31 , pp. 180-188
    • Weide, B.1    Carralot, J.P.2    Reese, A.3
  • 63
    • 67651152679 scopus 로고    scopus 로고
    • Direct injection of protamine-protected mRNA: Results of a phase 1/2 vaccination trial in metastatic melanoma patients
    • Weide B, Pascolo S, Scheel B, et al. Direct injection of protamine-protected mRNA: results of a phase 1/2 vaccination trial in metastatic melanoma patients. J Immunother 2009; 32: 498-507.
    • (2009) J Immunother , vol.32 , pp. 498-507
    • Weide, B.1    Pascolo, S.2    Scheel, B.3
  • 64
    • 85130432300 scopus 로고    scopus 로고
    • Intradermal vaccinations with RNA coding for TAA generate CD8(+) and CD4(+) immune responses and induce clinical benefit in vaccinated patients
    • [Epub ahead of print]
    • Rittig SM, Haentschel M, Weimer KJ, et al. Intradermal vaccinations with RNA coding for TAA generate CD8(+) and CD4(+) immune responses and induce clinical benefit in vaccinated patients. Mol Ther 2010. [Epub ahead of print].
    • (2010) Mol Ther
    • Rittig, S.M.1    Haentschel, M.2    Weimer, K.J.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.