Tremor: Clinical phenomenology and assessment techniques

Tremor and Other Hyperkinetic Movements

Volumn 2, Issue , 2012, Pages

  Hess, Christopher W ^a   Pullman, Seth L ^a  

^a Department of Medicine   (United States)

Author keywords

Dystonia; Essential tremor; Motor physiology; Orthostatic tremor; Parkinson disease; Tremor

Indexed keywords

EID: 85115797723     PISSN: None     EISSN: 21608288     Source Type: Journal    
DOI: 10.5334/TOHM.115     Document Type: Article

References (94)

1. Marsden CD. Origins of normal and pathological tremor. In: Findley LJ, Capildeo R, eds. Movement Disorders: Tremor. New York: Oxford University Press; 1988:37-84.
2. Findley LJ. Classification of tremors. J Clin Neurophysiol 1996;13:122-132, http://dx.doi.org/10.1097/00004691-199603000-00003.
3. Deuschl G, Raethjen J, Lindemann M, Krack P. The pathophysiology of tremor. Muscle Nerve 2001;24:716-35, http://dx.doi.org/10.1002/mus.1063.
4. Elble RJ, Koller WC. Tremor. Baltimore: The Johns Hopkins University Press; 1990.
5. Louis ED, Barnes L, Wendt KJ, et al. A teaching videotape for the assessment of essential tremor. Mov Disord 2001;16:89-93, http://dx.doi.org/10.1002/1531-8257(200101)16:1, 89::AID-MDS1001.3.0.CO;2-L.
6. Fahn S, Tolosa E, Concepcion M. Clinical rating scale for tremor. In:Jankovic J, Tolosa E, eds. Parkinson’s Disease and Movement Disorders, 2nd ed. Baltimore: Williams and Wilkins; 1993:271-80.
7. Bain PG, Findley LJ. Assessing Tremor Severity. London: Smith-Gordon and Compant, Ltd; 1993.
8. Elble RJ, Comella C, Fahn S, et al. The essential tremor rating assessment scale (TETRAS). Mov Disord 2008;23:S357.
9. Louis ED, Ford B, Bismuth B. Reliability between two observers using a protocol for diagnosing essential tremor. Mov Disord 1998;13:287-293, http:// dx.doi.org/10.1002/mds.870130215.
10. Stacy MA, Elble RJ, Ondo WG, Wu SC, Hulihan J. Assessment of interrater and intrarater reliability of the Fahn-Tolosa-Marin Tremor Rating Scale in essential tremor. Mov Disord 2007;22:833-838, http://dx.doi.org/10.1002/mds.21412.
11. Pullman SL. Spiral analysis: a new technique for measuring tremor with a digitizing tablet. Mov Disord 1998;13:85-89, http://dx.doi.org/10.1002/mds.870131315.
12. Glaser EM, Ruchkin DS. Principles of Neurobiological Signal Analysis. New York: Academic Press; 1976.
13. Findley LJ, Koller WC. Essential tremor: a review. Neurology 1984;37:1194-1197, http://dx.doi.org/10.1212/WNL.37.7.1194.
14. Marsden CD. Origins of normal and pathological tremor. In: Findley LJ, Capildeo R, eds. Movement Disorders: Tremor. New York: Oxford University Press; 1984:37-84.
15. Pullman SL, Fahn S, Rueda J. Physiologic characterization of dystonic and essential tremors. Neurology 1992;42:471, http://dx.doi.org/10.1212/WNL.42.3.471.
16. Pullman SL, Goodin DS, Marquinez AI, Tabbal S, Rubin M. Clinical utility of surface EMG: report of the therapeutics and technology assessment subcommittee of the American Academy of Neurology. Neurology 2000;55:171-177, http://dx.doi.org/10.1212/WNL.55.2.171.
17. Elble RJ. Physiologic and essential tremor. Neurology 1986;36:225-231, http://dx.doi.org/10.1212/WNL.36.2.225.
18. Louis ED, Ford B, Pullman S, Baron K. How normal is ʼnormal’? Mild tremor in a multiethnic cohort of normal subjects. Arch Neurol 1998;55:222-227, http://dx.doi.org/10.1001/archneur.55.2.222.
19. Critchley E. Clinical manifestations of essential tremor. J Neurol Neurosurg Psychiatry 1972;35:365-372, http://dx.doi.org/10.1136/jnnp.35.3.365.
20. Hubble JP, Busenbark KL, Koller WC. Essential tremor. Clin Neuropharmacol 1989;12:453-482, http://dx.doi.org/10.1097/00002826-198912000-00001.
21. Elble RJ, Pullman SL, Matsumoto JY, Raethjen J, Deuschl G, Tintner R. Tremor amplitude is logarithmically related to 4- and 5-point tremor rating scales. Brain 2006;129:2660-2666, http://dx.doi.org/10.1093/ brain/awl190.
22. Elble RJ, Brilliant M, Leffler K, Higgins C. Quantification of essential tremor in writing and drawing. Mov Disord 1996;11:70-78, http://dx.doi.org/10.1002/mds.870110113.
23. Gescheider GA. Psychophysics: The Fundamentals. 3rd ed. Mahwah, NJ: L. Erlbaum Associates; 1997.
24. Stanley K, Hagenah J, Bruggemann N, et al. Digitized spiral analysis is a promising early motor marker for Parkinson Disease. Parkinsonism Relat Disord 2010;16:233-234, http://dx.doi.org/10.1016/j.parkreldis.2009.12.007.
25. Hallett M. Overview of human tremor physiology. Mov Disord 1998;13:43-48, http://dx.doi.org/10.1002/mds.870131308.
26. Mure H, Hirano S, Tang CC, et al. Parkinson’s disease tremor-related metabolic network: characterization, progression, and treatment effects. Neuroimage 2011;54:1244-1253, http://dx.doi.org/10.1016/j.neuroimage.2010.09.028.
27. Timmermann L, Gross J, Dirks M, Volkmann J, Freund HJ, Schnitzler A. The cerebral oscillatory network of parkinsonian resting tremor. Brain 2003; 126:199-212, http://dx.doi.org/10.1093/brain/awg022.
28. Louis ED, Okun MS. It is time to remove the ‘benign’ from the essential tremor label. Parkinsonism Relat Disord 2011;17:516-520, http://dx.doi.org/10.1016/j.parkreldis.2011.03.012.
29. Louis ED. Essential tremor: evolving clinicopathological concepts in an era of intensive post-mortem enquiry. Lancet Neurol 2010;9:613-622, http://dx. doi.org/10.1016/S1474-4422(10)70090-9.
30. Louis ED. Essential tremor. Handb Clin Neurol 2011;100:433-448, http:// dx.doi.org/10.1016/B978-0-444-52014-2.00033-1.
31. Deuschl G, Elble RJ. The pathophysiology of essential tremor. Neurology 2000;54:S14-20, http://dx.doi.org/10.1212/WNL.54.4.14A.
32. Moore GP, Ding L, Bronte-Stewart HM. Concurrent Parkinson tremors. J Physiol 2000;529:273-281, http://dx.doi.org/10.1111/j.1469-7793.2000.00273.x.
33. Lauk M, Koster B, Timmer J, Guschlbauer B, Deuschl G, Lucking CH. Side-to-side correlation of muscle activity in physiological and pathological human tremors. Clin Neurophysiol 1999;110:1774-1783, http://dx.doi.org/10.1016/S1388-2457(99)00130-3.
34. Raethjen J, Lindemann M, Schmaljohann H, Wenzelburger R, Pfister G, Deuschl G. Multiple oscillators are causing parkinsonian and essential tremor. Mov Disord 2000;15:84-94, http://dx.doi.org/10.1002/1531-8257(200001)15:1, 84::AID-MDS1014.3.0.CO;2-K.
35. Hallett M, Deuschl G. Are we making progress in the understanding of tremor in Parkinson’s disease? Ann Neurol 2010;68:780-781, http://dx.doi.org/10.1002/ana.22253.
36. Deuschl G, Raethjen J, Baron R, Lindemann M, Wilms H, Krack P. The pathophysiology of parkinsonian tremor: a review. J Neurol 2000;247 Suppl 5:V33-48, http://dx.doi.org/10.1007/PL00007781.
37. Louis ED, Asabere N, Agnew A, et al. Rest tremor in advanced essential tremor: a post-mortem study of nine cases. J Neurol Neurosurg Psychiatry 2011;82:261-265, http://dx.doi.org/10.1136/jnnp.2010.215681.
38. Elble RJ, Deuschl G. An update on essential tremor. Curr Neurol Neurosci Rep 2009;9:273-277, http://dx.doi.org/10.1007/s11910-009-0041-6.
39. Cohen O, Pullman S, Jurewicz E, Watner D, Louis ED. Rest tremor in patients with essential tremor: prevalence, clinical correlates, and electrophysiologic characteristics. Arch Neurol 2003;60:405-410, http://dx.doi.org/10.1001/archneur.60.3.405.
40. Paviour DC, Jager HR, Wilkinson L, Jahanshahi M, Lees AJ. Holmes tremor: application of modern neuroimaging techniques. Mov Disord 2006;21:2260-2262, http://dx.doi.org/10.1002/mds.20981.
41. Krystkowiak P, Martinat P, Cassim F, et al. Thalamic tremor:correlations with three-dimensional magnetic resonance imaging data and pathophysiological mechanisms. Mov Disord 2000;15:911-918, http://dx.doi. org/10.1002/1531-8257(200009)15:5, 911::AID-MDS1023.3.0.CO;2-B.
42. Louis ED, Pullman SL, Eidelberg D, Dhawan V. Re-emergent tremor without accompanying rest tremor in Parkinson’s disease. Can J Neurol Sci 2008; 35:513-515.
43. Deuschl G, Bain P, Brin M. Consensus statement of the Movement Disorder Society on Tremor. Ad Hoc Scientific Committee. Mov Disord 1998; 13:2-23, http://dx.doi.org/10.1002/mds.870131303.
44. Louis ED, Dure LS, Pullman S. Essential tremor in childhood: a series of nineteen cases. Mov Disord 2001;16:921-923, http://dx.doi.org/10.1002/ mds.1182.
45. Brennan KC, Jurewicz EC, Ford B, Pullman SL, Louis ED. Is essential tremor predominantly a kinetic or a postural tremor? A clinical and electrophysiological study. Mov Disord 2002;17:313-316, http://dx.doi.org/10.1002/mds.10003.
46. Hess CW, Saunders-Pullman R. Movement disorders and alcohol misuse. Addict Biol 2006;11:117-125, http://dx.doi.org/10.1111/j.1369-1600.2006.00017.x.
47. Deuschl G, Bain P, Brin M. Consensus statement of the Movement Disorder Society on Tremor. Ad Hoc Scientific Committee. Mov Disord 1998;13 Suppl 3:2-23.
48. Jankovic J, Cardoso F, Grossman RG, Hamilton WJ. Outcome after stereotactic thalamotomy for parkinsonian, essential, and other types of tremor. Neurosurgery 1995;37:680-686; discussion 6-7, http://dx.doi.org/10.1227/00006123-199510000-00011.
49. Heilman KM. Orthostatic tremor. Arch Neurol 1984;41:880-881, http:// dx.doi.org/10.1001/archneur.1984.04050190086020.
50. Gerschlager W, Brown P. Orthostatic tremor-a review. Handb Clin Neurol 2011;100:457-462, http://dx.doi.org/10.1016/B978-0-444-52014-2.00035-5.
51. FitzGerald PM, Jankovic J. Orthostatic tremor: an association with essential tremor. Mov Disord 1991;6:60-64, http://dx.doi.org/10.1002/mds.870060111.
52. de Bie RM, Chen R, Lang AE. Orthostatic tremor in progressive supranuclear palsy. Mov Disord 2007;22:1192-1194, http://dx.doi.org/10.1002/mds.21434.
53. Gerschlager W, Munchau A, Katzenschlager R, et al. Natural history and syndromic associations of orthostatic tremor: a review of 41 patients. Mov Disord 2004;19:788-795, http://dx.doi.org/10.1002/mds.20132.
54. Piboolnurak P, Yu QP, Pullman SL. Clinical and neurophysiologic spectrum of orthostatic tremor: case series of 26 subjects. Mov Disord 2005;20:1455-1461, http://dx.doi.org/10.1002/mds.20588.
55. Fischer M, Kress W, Reiners K, Rieckmann P. Orthostatic tremor in three brothers. J Neurol 2007;254:1759-1760, http://dx.doi.org/10.1007/ s00415-007-0647-z.
56. Brown P. New clinical sign for orthostatic tremor. Lancet 1995;346:306-307, http://dx.doi.org/10.1016/S0140-6736(95)92190-7.
57. Boroojerdi B, Ferbert A, Foltys H, Kosinski CM, Noth J, Schwarz M. Evidence for a non-orthostatic origin of orthostatic tremor. J Neurol Neurosurg Psychiatry 1999;66:284-288, http://dx.doi.org/10.1136/jnnp.66.3.284.
58. Walker FO, McCormick GM, Hunt VP. Isometric features of orthostatic tremor: an electromyographic analysis. Muscle Nerve 1990;13:918-922, http:// dx.doi.org/10.1002/mus.880131006.
59. Sharott A, Marsden J, Brown P. Primary orthostatic tremor is an exaggeration of a physiological response to instability. Mov Disord 2003;18:195-199, http://dx.doi.org/10.1002/mds.10324.
60. Koster B, Lauk M, Timmer J, et al. Involvement of cranial muscles and high intermuscular coherence in orthostatic tremor. Ann Neurol 1999;45:384-388, http://dx.doi.org/10.1002/1531-8249(199903)45:3, 384::AID-ANA15.3.0.CO;2-J.
61. Manto MU, Setta F, Legros B, Jacquy J, Godaux E. Resetting of orthostatic tremor associated with cerebellar cortical atrophy by transcranial magnetic stimulation. Arch Neurol 1999;56:1497-500, http://dx.doi.org/10.1001/archneur.56.12.1497.
62. Wasielewski PG, Burns JM, Koller WC. Pharmacologic treatment of tremor. Mov Disord 1998;13:90-100, http://dx.doi.org/10.1002/mds.870131316.
63. Guridi J, Rodriguez-Oroz MC, Arbizu J, et al. Successful thalamic deep brain stimulation for orthostatic tremor. Mov Disord 2008;23:1808-1811, http:// dx.doi.org/10.1002/mds.22001.
64. Magarinos-Ascone C, Ruiz FM, Millan AS, et al. Electrophysiological evaluation of thalamic DBS for orthostatic tremor. Mov Disord 2010;25:2476-2477, http://dx.doi.org/10.1002/mds.23333.
65. Gironell A, Kulisevsky J. Diagnosis and management of essential tremor and dystonic tremor. Ther Adv Neurol Disord 2009;2:215-222, http://dx.doi.org/10.1177/1756285609104791.
66. Bain PG. Dystonic tremor presenting as parkinsonism: long-term followup of SWEDDs. Neurology 2009;72:1443-1445, http://dx.doi.org/10.1212/ WNL.0b013e3181a18809.
67. Deuschl G, Bergman H. Pathophysiology of nonparkinsonian tremors. Mov Disord 2002;17 Suppl 3:S41-48, http://dx.doi.org/10.1002/mds.10141.
68. Pedersen SF, Pullman SL, Latov N, Brannagan TH, 3rd. Physiological tremor analysis of patients with anti-myelin-associated glycoprotein associated neuropathy and tremor. Muscle Nerve 1997;20:38-44, http://dx.doi.org/10.1002/(SICI)1097-4598(199701)20:1, 38::AID-MUS5.3.0.CO;2-I.
69. Weiss D, Govindan RB, Rilk A, et al. Central oscillators in a patient with neuropathic tremor: evidence from intraoperative local field potential recordings. Mov Disord 2011;26:323-327, http://dx.doi.org/10.1002/mds.23374.
70. Bain PG. Task-specific tremor. Handb Clin Neurol 2011;100:711-718, http://dx.doi.org/10.1016/B978-0-444-52014-2.00050-1.
71. Morgan JCS, K.D. Drug-induced tremors. Lancet Neurol 2005;4:866-876, http://dx.doi.org/10.1016/S1474-4422(05)70250-7.
72. Lorberboym M, Treves TA, Melamed E, Lampl Y, Hellmann M, Djaldetti R. [123I]-FP/CIT SPECT imaging for distinguishing drug-induced parkinsonism from Parkinson’s disease. Mov Disord 2006;21:510-514, http://dx. doi.org/10.1002/mds.20748.
73. Fahn S, Jankovic J. Principles and Practice of Movement Disorders. Philadelphia: Churchill Livingstone/Elsevier; 2007.
74. Zadikoff C, Munhoz RP, Asante AN, et al. Movement disorders in patients taking anticonvulsants. J Neurol Neurosurg Psychiatry 2007;78:147-151, http://dx.doi.org/10.1136/jnnp.2006.100222.
75. Bunney WE, Wehr TR, Gillin JC, Post RM, Goodwin FK, van Kammen DP. The switch process in manic-depressive psychosis. Ann Intern Med 1977;87:319-335.
76. Prien RF. Lithium in the treatment of affective disorders. Clin Neuropharmacol 1978;3:113-131, http://dx.doi.org/10.1097/00002826-197800030-00008.
77. Lapierre YD. Control of lithium tremor with propranolol. Can Med Assoc J 1976;114:619-620.
78. Tyrer P, Shopsin B. Neural and neuromuscular side effects of lithium. In:Johnson FN, ed. Handbook of Lithium Therapy. Lancaster:MTP Press; 1980:289-309.
79. Vestergaard P, Poulstrup I, Schou M. Prospective studies on a lithium cohort. 3. Tremor, weight gain, diarrhea, psychological complaints. Acta Psychiatry Scand 1988:434-441, http://dx.doi.org/10.1111/j.1600-0447.1988. tb06363.x.
80. Pullinger S, Tyrer P. Acute lithium-induced tremor. Br J Psychiatry 1983; 143:40-41, http://dx.doi.org/10.1192/bjp.143.1.40.
81. Brown WT. The pattern of lithium side effects and toxic reactions in the course of lithium therapy. In: Handbook of Lithium Therapy. Baltimore: University Park Press; 1980:Chapter 33.
82. Karas BJ, Wilder BJ, Hammond EF, Bauman AW. Treatment of valproate tremors. Neurology 1983;33:1380-1382, http://dx.doi.org/10.1212/ WNL.33.10.1380.
83. Coulter DM, Edwards IR, Savage RL. Survey of neurological problems with amiodarone in the New Zealand Intensive Medicines Monitoring Programme. N Z Med J 1990;103:98-100.
84. Puschmann A, Wszolek ZK. Diagnosis and treatment of common forms of tremor. Semin Neurol 2011;31:65-77, http://dx.doi.org/10.1055/s-0031-1271312.
85. Hess C, Saunders-Pullman R. Hyperkinetic movement disorders. In:Verster JC, Conrod P, Brady K, Galanter M, eds. Drug Abuse and Addiction in Medical Illness. New York: Springer; July 2012.
86. Marjama J, Troster AI, Koller WC. Psychogenic movement disorders. Neurol Clin 1995;13:283-297.
87. Kim YJ, Pakiam AS, Lang AE. Historical and clinical features of psychogenic tremor: a review of 70 cases. Can J Neurol Sci 1999;26:190-195.
88. Koller W, Lang A, Vetere-Overfield B, et al. Psychogenic tremors. Neurology 1989;39:1094-1099, http://dx.doi.org/10.1212/WNL.39.8.1094.
89. McAuley JH, Rothwell JC, Marsden CD, Findley LJ. Electrophysiological aids in distinguishing organic from psychogenic tremor. Neurology 1998;50:1882-1884, http://dx.doi.org/10.1212/WNL.50.6.1882.
90. Piboolnurak P, Rothey N, Ahmed A, et al. Psychogenic tremor disorders identified using tree-based statistical algorithms and quantitative tremor analysis. Mov Disord 2005;20:1543-1549, http://dx.doi.org/10.1002/mds.20634.
91. Zeuner KE, Shoge RO, Goldstein SR, Dambrosia JM, Hallett M. Accelerometry to distinguish psychogenic from essential or parkinsonian tremor. Neurology 2003;61:548-550, http://dx.doi.org/10.1212/01.WNL.0000076183.34915.CD.
92. Williams DT, Ford B, Fahn S. Phenomenology and psychopathology related to psychogenic movement disorders. Adv Neurol 1995;65:231-257.
93. Regragui W, Gerdelat-Mas A, Simonetta-Moreau M. Cortical tremor (FCMTE: familial cortical myoclonic tremor with epilepsy). Neurophysiol Clin 2006;36:345-349, http://dx.doi.org/10.1016/j.neucli.2006.12.005.
94. Toro C, Pascual-Leone A, Deuschl G, Tate E, Pranzatelli MR, Hallett M. Cortical tremor. A common manifestation of cortical myoclonus. Neurology 1993;43:2346-2353, http://dx.doi.org/10.1212/WNL.43.11.2346.