메뉴 건너뛰기




Volumn 218, Issue 3, 2021, Pages 135-142

Omega-3 and polyunsaturated fat for prevention of depression and anxiety symptoms: Systematic review and meta-analysis of randomised trials

Author keywords

anxiety; depression; Fatty acids omega 3; fatty acids omega 6; meta analysis

Indexed keywords

ANTIDEPRESSANT AGENT; LINOLENIC ACID; OMEGA 3 FATTY ACID; OMEGA 6 FATTY ACID;

EID: 85101513325     PISSN: 00071250     EISSN: 14721465     Source Type: Journal    
DOI: 10.1192/bjp.2019.234     Document Type: Review
Times cited : (65)

References (70)
  • 1
    • 84898542601 scopus 로고    scopus 로고
    • U.S. Adults are not meeting recommended levels for fish and omega-3 fatty acid intake: Results of an analysis using observational data from NHANES 2003-2008
    • Papanikolaou Y, Brooks J, Reider C, Fulgoni VL. U.S. adults are not meeting recommended levels for fish and omega-3 fatty acid intake: results of an analysis using observational data from NHANES 2003-2008. Nutr J 2014; 13: 31.
    • (2014) Nutr J , vol.13 , pp. 31
    • Papanikolaou, Y.1    Brooks, J.2    Reider, C.3    Fulgoni, V.L.4
  • 2
    • 85056187313 scopus 로고    scopus 로고
    • Global, regional, and national disability-adjusted life-years (DALYs) for 359 diseases and injuries and healthy life expectancy (HALE) for 195 countries and territories, 1990-2017: A systematic analysis for the Global Burden of Disease Study 2017
    • 10159
    • Kyu HH, Abate D, Abate KH, Abay SM, Abbafati C, Abbasi N, et al. Global, regional, and national disability-adjusted life-years (DALYs) for 359 diseases and injuries and healthy life expectancy (HALE) for 195 countries and territories, 1990-2017: a systematic analysis for the Global Burden of Disease Study 2017. Lancet 2018; 392(10159): 1859-922.
    • (2018) Lancet , vol.392 , pp. 1859-1922
    • Kyu, H.H.1    Abate, D.2    Abate, K.H.3    Abay, S.M.4    Abbafati, C.5    Abbasi, N.6
  • 3
    • 2542498720 scopus 로고    scopus 로고
    • Prevalence, severity, and unmet need for treatment of mental disorders in the World Health Organization World Mental Health Surveys
    • Demyttenaere K, Bruffaerts R, Posada-Villa J, Gasquet I, Kovess V, Lepine JP, et al. Prevalence, severity, and unmet need for treatment of mental disorders in the World Health Organization World Mental Health Surveys. JAMA 2004; 291(21): 2581-90.
    • (2004) JAMA , vol.291 , Issue.21 , pp. 2581-2590
    • Demyttenaere, K.1    Bruffaerts, R.2    Posada-Villa, J.3    Gasquet, I.4    Kovess, V.5    Lepine, J.P.6
  • 4
    • 35748945434 scopus 로고    scopus 로고
    • Lifetime prevalence and age-of-onset distributions of mental disorders in the World Health Organization's World Mental Health Survey Initiative
    • Kessler RC, Angermeyer M, Anthony JC, De Graaf R, Demyttenaere K, Gasquet I, et al. Lifetime prevalence and age-of-onset distributions of mental disorders in the World Health Organization's World Mental Health Survey Initiative. World Psychiatry 2007; 6(3): 168-76.
    • (2007) World Psychiatry , vol.6 , Issue.3 , pp. 168-176
    • Kessler, R.C.1    Angermeyer, M.2    Anthony, J.C.3    De Graaf, R.4    Demyttenaere, K.5    Gasquet, I.6
  • 5
    • 85045608710 scopus 로고    scopus 로고
    • Prevalence of depression and depressive symptoms among outpatients: A systematic review and metaanalysis
    • Wang J, Wu X, Lai W, Long E, Zhang X, Li W, et al. Prevalence of depression and depressive symptoms among outpatients: a systematic review and metaanalysis. BMJ Open 2017; 7(8): e017173.
    • (2017) BMJ Open , vol.7 , Issue.8 , pp. e017173
    • Wang, J.1    Wu, X.2    Lai, W.3    Long, E.4    Zhang, X.5    Li, W.6
  • 7
    • 84887659655 scopus 로고    scopus 로고
    • The prevalence of depression in rheumatoid arthritis: A systematic review and meta-analysis
    • Matcham F, Rayner L, Steer S, Hotopf M. The prevalence of depression in rheumatoid arthritis: a systematic review and meta-analysis. Rheumatology (Oxford) 2013; 52(12): 2136-48.
    • (2013) Rheumatology (Oxford) , vol.52 , Issue.12 , pp. 2136-2148
    • Matcham, F.1    Rayner, L.2    Steer, S.3    Hotopf, M.4
  • 8
    • 84928808048 scopus 로고    scopus 로고
    • Long-chain omega-3 fatty acids and the brain: A review of the independent and shared effects of EPA, DPA and DHA
    • Dyall SC. Long-chain omega-3 fatty acids and the brain: a review of the independent and shared effects of EPA, DPA and DHA. Front Aging Neurosci 2015; 7: 52.
    • (2015) Front Aging Neurosci , vol.7 , pp. 52
    • Dyall, S.C.1
  • 9
    • 84939504822 scopus 로고    scopus 로고
    • Omega-3 polyunsaturated fatty acids in prevention of mood and anxiety disorders
    • Su K-P, Matsuoka Y, Pae C-U. Omega-3 polyunsaturated fatty acids in prevention of mood and anxiety disorders. Clin Psychopharmacol Neurosci 2015; 13(2): 129-37.
    • (2015) Clin Psychopharmacol Neurosci , vol.13 , Issue.2 , pp. 129-137
    • Su, K.-P.1    Matsuoka, Y.2    Pae, C.-U.3
  • 10
    • 85054930866 scopus 로고    scopus 로고
    • Food for mood: Relevance of nutritional omega-3 fatty acids for depression and anxiety
    • Larrieu T, Layé S. Food for mood: relevance of nutritional omega-3 fatty acids for depression and anxiety. Front Physiol 2018; 9: 1047.
    • (2018) Front Physiol , vol.9 , pp. 1047
    • Larrieu, T.1    Layé, S.2
  • 11
    • 84982285468 scopus 로고    scopus 로고
    • Dietary n-3 PUFA, fish consumption and depression: A systematic review and meta-analysis of observational studies
    • Grosso G, Micek A, Marventano S, Castellano S, Mistretta A, Pajak A, et al. Dietary n-3 PUFA, fish consumption and depression: a systematic review and meta-analysis of observational studies. J Affect Disord 2016; 205: 269-81.
    • (2016) J Affect Disord , vol.205 , pp. 269-281
    • Grosso, G.1    Micek, A.2    Marventano, S.3    Castellano, S.4    Mistretta, A.5    Pajak, A.6
  • 13
    • 31344470083 scopus 로고    scopus 로고
    • Red cell membrane omega-3 fatty acids are decreased in nondepressed patients with social anxiety disorder
    • Green P, Hermesh H, Monselise A, Marom S, Presburger G, Weizman A. Red cell membrane omega-3 fatty acids are decreased in nondepressed patients with social anxiety disorder. Eur Neuropsychopharmacol 2006; 16(2): 107-13.
    • (2006) Eur Neuropsychopharmacol , vol.16 , Issue.2 , pp. 107-113
    • Green, P.1    Hermesh, H.2    Monselise, A.3    Marom, S.4    Presburger, G.5    Weizman, A.6
  • 18
    • 85069847908 scopus 로고    scopus 로고
    • The relationship between omega-3, omega-6 and total polyunsaturated fat and musculoskeletal health and functional status in adults: A systematic review and meta-analysis of RCTs
    • The PUFAH Group
    • Abdelhamid A, Hooper L, Sivakaran R, Hayhoe RPG, Welch A, The PUFAH Group. The relationship between omega-3, omega-6 and total polyunsaturated fat and musculoskeletal health and functional status in adults: a systematic review and meta-analysis of RCTs. Calcif Tissue Int 2019; 105: 353-72.
    • (2019) Calcif Tissue Int , vol.105 , pp. 353-372
    • Abdelhamid, A.1    Hooper, L.2    Sivakaran, R.3    Hayhoe, R.P.G.4    Welch, A.5
  • 19
    • 85069866781 scopus 로고    scopus 로고
    • Omega-3, omega-6, and total dietary polyunsaturated fat for prevention and treatment of type 2 diabetes mellitus: Systematic review and meta-analysis of randomised controlled trials
    • Brown TJ, Brainard J, Song F, Wang X, Abdelhamid A, Hooper L. Omega-3, omega-6, and total dietary polyunsaturated fat for prevention and treatment of type 2 diabetes mellitus: systematic review and meta-analysis of randomised controlled trials. BMJ 2019; 366: l4697.
    • (2019) BMJ , vol.366 , pp. l4697
    • Brown, T.J.1    Brainard, J.2    Song, F.3    Wang, X.4    Abdelhamid, A.5    Hooper, L.6
  • 20
    • 85101536625 scopus 로고    scopus 로고
    • Omega-3, omega-6 and total polyunsaturated fat for cognition and dementia: Systematic review and meta-analysis of RCTs
    • in press
    • Brainard J, Jimoh OF, Deane K, Biswas P, Donaldson D, Maas K, et al. Omega-3, omega-6 and total polyunsaturated fat for cognition and dementia: systematic review and meta-analysis of RCTs. JAMDA, in press, 2019.
    • (2019) JAMDA
    • Brainard, J.1    Jimoh, O.F.2    Deane, K.3    Biswas, P.4    Donaldson, D.5    Maas, K.6
  • 21
    • 85081403708 scopus 로고    scopus 로고
    • Omega-3, omega-6 and total dietary polyunsaturated fat on cancer incidence: Systematic review and meta-analysis of randomised trials
    • in press
    • Hanson S, Thorpe G, Winstanley L, Abdelhamid AS, Hooper L. Omega-3, omega-6 and total dietary polyunsaturated fat on cancer incidence: systematic review and meta-analysis of randomised trials. Br J Cancer, in press, 2019.
    • (2019) Br J Cancer
    • Hanson, S.1    Thorpe, G.2    Winstanley, L.3    Abdelhamid, A.S.4    Hooper, L.5
  • 22
    • 85066878329 scopus 로고    scopus 로고
    • Creation of a database to assess effects of omega-3, omega-6 and total polyunsaturated fats on health: Database and methodology for a set of reviews
    • Hooper L, Abdelhamid A, Brainard J, Deane KHO, Song F. Creation of a database to assess effects of omega-3, omega-6 and total polyunsaturated fats on health: database and methodology for a set of reviews. BMJ Open 2019; 9(5): e029554.
    • (2019) BMJ Open , vol.9 , Issue.5 , pp. e029554
    • Hooper, L.1    Abdelhamid, A.2    Brainard, J.3    Deane, K.H.O.4    Song, F.5
  • 24
    • 84866602767 scopus 로고    scopus 로고
    • Incorporation of eicosapentaenoic and docosahexaenoic acids into lipid pools when given as supplements providing doses equivalent to typical intakes of oily fish
    • Browning LM, Walker CG, Mander AP, West AL, Madden J, Gambell JM, et al. Incorporation of eicosapentaenoic and docosahexaenoic acids into lipid pools when given as supplements providing doses equivalent to typical intakes of oily fish. Am J Clin Nutr 2012; 96(4): 748-58.
    • (2012) Am J Clin Nutr , vol.96 , Issue.4 , pp. 748-758
    • Browning, L.M.1    Walker, C.G.2    Mander, A.P.3    West, A.L.4    Madden, J.5    Gambell, J.M.6
  • 25
    • 70049099036 scopus 로고    scopus 로고
    • Chapter 8: Assessing risk of bias in included studies
    • Cochrane Statistical Methods Group, Cochrane Bias Methods Group, [updated March 2011] (eds JPT Higgins, S Green): section 8.5. The Cochrane Collaboration
    • Higgins JPT, Altman DG, Sterne JAC, Cochrane Statistical Methods Group, Cochrane Bias Methods Group. Chapter 8: Assessing risk of bias in included studies. In Cochrane Handbook for Systematic Reviews of Interventions Version 510 [updated March 2011] (eds JPT Higgins, S Green): section 8.5. The Cochrane Collaboration, 2011.
    • (2011) Cochrane Handbook for Systematic Reviews of Interventions Version , vol.510
    • Higgins, J.P.T.1    Altman, D.G.2    Sterne, J.A.C.3
  • 26
    • 85003698528 scopus 로고    scopus 로고
    • Impact of analysing continuous outcomes using final values, change scores and analysis of covariance on the performance of meta-analytic methods: A simulation study
    • McKenzie JE, Herbison GP, Deeks JJ. Impact of analysing continuous outcomes using final values, change scores and analysis of covariance on the performance of meta-analytic methods: a simulation study. Res Synth Methods 2016; 7(4): 371-86.
    • (2016) Res Synth Methods , vol.7 , Issue.4 , pp. 371-386
    • McKenzie, J.E.1    Herbison, G.P.2    Deeks, J.J.3
  • 27
    • 85101534775 scopus 로고    scopus 로고
    • Review Manager (RevMan) Version 5.3., The Cochrane Collaboration
    • Review Manager (RevMan) Version 5.3. The Cochrane Collaboration, 2014 (https://community.cochrane.org/help/tools-and-software/revman-5/revman-5-download/installation).
    • (2014)
  • 28
    • 84355163139 scopus 로고    scopus 로고
    • The effect of low-dose omega 3 fatty acids on the treatment of mild to moderate depression in the elderly: A double-blind, randomized, placebo-controlled study
    • Tajalizadekhoob Y, Sharifi F, Fakhrzadeh H, Mirarefin M, Ghaderpanahi M, Badamchizade Z, et al. The effect of low-dose omega 3 fatty acids on the treatment of mild to moderate depression in the elderly: a double-blind, randomized, placebo-controlled study. Eur Arch Psychiatry Clin Neurosci 2011; 261(8): 539-49.
    • (2011) Eur Arch Psychiatry Clin Neurosci , vol.261 , Issue.8 , pp. 539-549
    • Tajalizadekhoob, Y.1    Sharifi, F.2    Fakhrzadeh, H.3    Mirarefin, M.4    Ghaderpanahi, M.5    Badamchizade, Z.6
  • 29
    • 33748090675 scopus 로고    scopus 로고
    • A modified test for small-study effects in meta-analyses of controlled trials with binary endpoints
    • Harbord RM, Egger M, Sterne JAC. A modified test for small-study effects in meta-analyses of controlled trials with binary endpoints. Stat Med 2006; 25 (20): 3443-57.
    • (2006) Stat Med , vol.25 , Issue.20 , pp. 3443-3457
    • Harbord, R.M.1    Egger, M.2    Sterne, J.A.C.3
  • 30
    • 78549233384 scopus 로고    scopus 로고
    • Alpha Omega Trial Group. N-3 fatty acids and cardiovascular events after myocardial infarction
    • Kromhout D, Giltay EJ, Geleijnse JM. Alpha Omega Trial Group. n-3 fatty acids and cardiovascular events after myocardial infarction. N Engl J Med 2010; 363 (21): 2015-26.
    • (2010) N Engl J Med , vol.363 , Issue.21 , pp. 2015-2026
    • Kromhout, D.1    Giltay, E.J.2    Geleijnse, J.M.3
  • 31
    • 84940535056 scopus 로고    scopus 로고
    • Effect of omega-3 fatty acids, lutein/zeaxanthin, or other nutrient supplementation on cognitive function: The AREDS2 randomized clinical trial
    • Chew EY, Clemons TE, Agron E, Launer LJ, Grodstein F, Bernstein PS, et al. Effect of omega-3 fatty acids, lutein/zeaxanthin, or other nutrient supplementation on cognitive function: the AREDS2 randomized clinical trial. JAMA 2015; 314(8): 791-801.
    • (2015) JAMA , vol.314 , Issue.8 , pp. 791-801
    • Chew, E.Y.1    Clemons, T.E.2    Agron, E.3    Launer, L.J.4    Grodstein, F.5    Bernstein, P.S.6
  • 32
    • 47749114025 scopus 로고    scopus 로고
    • The effects of omega-3 fatty acids monotherapy in Alzheimer's disease and mild cognitive impairment: A preliminary randomized double-blind placebo-controlled study
    • Chiu CC, Su KP, Cheng TC, Liu HC, Chang CJ, Dewey ME, et al. The effects of omega-3 fatty acids monotherapy in Alzheimer's disease and mild cognitive impairment: a preliminary randomized double-blind placebo-controlled study. Prog Neuropsychopharmacol Biol Psychiatry 2008; 32(6): 1538-44.
    • (2008) Prog Neuropsychopharmacol Biol Psychiatry , vol.32 , Issue.6 , pp. 1538-1544
    • Chiu, C.C.1    Su, K.P.2    Cheng, T.C.3    Liu, H.C.4    Chang, C.J.5    Dewey, M.E.6
  • 34
    • 84979284381 scopus 로고    scopus 로고
    • Effects of n-3 PUFAs on fasting plasma glucose and insulin resistance in patients with impaired fasting glucose or impaired glucose tolerance
    • Derosa G, Cicero AF, D'Angelo A, Borghi C, Maffioli P. Effects of n-3 PUFAs on fasting plasma glucose and insulin resistance in patients with impaired fasting glucose or impaired glucose tolerance. BioFactors 2016; 42(3): 316-22.
    • (2016) BioFactors , vol.42 , Issue.3 , pp. 316-322
    • Derosa, G.1    Cicero, A.F.2    D'Angelo, A.3    Borghi, C.4    Maffioli, P.5
  • 35
    • 84923925504 scopus 로고    scopus 로고
    • Dietary n-3/long-chain n-3 polyunsaturated fatty acids for prevention of sporadic colorectal tumors: A randomized controlled trial in polypectomized participants
    • Tokudome S, Kuriki K, Yokoyama Y, Sasaki M, Joh T, Kamiya T, et al. Dietary n-3/long-chain n-3 polyunsaturated fatty acids for prevention of sporadic colorectal tumors: a randomized controlled trial in polypectomized participants. Prostaglandins Leukot Essent Fatty Acids 2015; 94: 1-11.
    • (2015) Prostaglandins Leukot Essent Fatty Acids , vol.94 , pp. 1-11
    • Tokudome, S.1    Kuriki, K.2    Yokoyama, Y.3    Sasaki, M.4    Joh, T.5    Kamiya, T.6
  • 36
    • 77952950559 scopus 로고    scopus 로고
    • The influence of long-term awareness of hyperlipidemia and of 3 years of dietary counseling on depression, anxiety, and quality of life
    • Einvik G, Ekeberg O, Lavik JG, Ellingsen I, Klemsdal TO, Hjerkinn EM. The influence of long-term awareness of hyperlipidemia and of 3 years of dietary counseling on depression, anxiety, and quality of life. J Psychosom Res 2010; 68(6): 567-72.
    • (2010) J Psychosom Res , vol.68 , Issue.6 , pp. 567-572
    • Einvik, G.1    Ekeberg, O.2    Lavik, J.G.3    Ellingsen, I.4    Klemsdal, T.O.5    Hjerkinn, E.M.6
  • 37
    • 84904661185 scopus 로고    scopus 로고
    • No significant effects of ethyl-eicosapentanoic acid on histologic features of nonalcoholic steatohepatitis in a phase 2 trial
    • Sanyal AJ, Abdelmalek MF, Suzuki A, Cummings OW, Chojkier M, Group E. No significant effects of ethyl-eicosapentanoic acid on histologic features of nonalcoholic steatohepatitis in a phase 2 trial. Gastroenterology 2014; 147(2): 377-84.
    • (2014) Gastroenterology , vol.147 , Issue.2 , pp. 377-384
    • Sanyal, A.J.1    Abdelmalek, M.F.2    Suzuki, A.3    Cummings, O.W.4    Chojkier, M.5    Group, E.6
  • 38
    • 84894275464 scopus 로고    scopus 로고
    • Cognitive performance in older adults is inversely associated with fish consumption but not erythrocyte membrane n-3 fatty acids
    • Danthiir V, Hosking D, Burns NR, Wilson C, Nettelbeck T, Calvaresi E, et al. Cognitive performance in older adults is inversely associated with fish consumption but not erythrocyte membrane n-3 fatty acids. J Nutr 2014; 144(3): 311-20.
    • (2014) J Nutr , vol.144 , Issue.3 , pp. 311-320
    • Danthiir, V.1    Hosking, D.2    Burns, N.R.3    Wilson, C.4    Nettelbeck, T.5    Calvaresi, E.6
  • 39
    • 84941037812 scopus 로고    scopus 로고
    • Ethyl-eicosapentaenoic acid treatment in Huntington's disease: A placebocontrolled clinical trial
    • Ferreira JJ, Rosser A, Craufurd D, Squitieri F, Mallard N, Landwehrmeyer B. Ethyl-eicosapentaenoic acid treatment in Huntington's disease: a placebocontrolled clinical trial. Mov Disord 2015; 30(10): 1426-9.
    • (2015) Mov Disord , vol.30 , Issue.10 , pp. 1426-1429
    • Ferreira, J.J.1    Rosser, A.2    Craufurd, D.3    Squitieri, F.4    Mallard, N.5    Landwehrmeyer, B.6
  • 40
    • 84957990533 scopus 로고    scopus 로고
    • Beneficial effects of dietary docosahexaenoic acid intervention on cognitive function and mental health of the oldest elderly in Japanese care facilities and nursing homes
    • Hashimoto M, Kato S, Tanabe Y, Katakura M, Mamun AA, Ohno M, et al. Beneficial effects of dietary docosahexaenoic acid intervention on cognitive function and mental health of the oldest elderly in Japanese care facilities and nursing homes. Geriatr Gerontol Int 2016; 17(2): 330-7.
    • (2016) Geriatr Gerontol Int , vol.17 , Issue.2 , pp. 330-337
    • Hashimoto, M.1    Kato, S.2    Tanabe, Y.3    Katakura, M.4    Mamun, A.A.5    Ohno, M.6
  • 41
    • 84958049677 scopus 로고    scopus 로고
    • DHA supplementation alone or in combination with other nutrients does not modulate cerebral hemodynamics or cognitive function in healthy older adults
    • Jackson PA, Forster JS, Bell JG, Dick JR, Younger I, Kennedy DO. DHA supplementation alone or in combination with other nutrients does not modulate cerebral hemodynamics or cognitive function in healthy older adults. Nutrients 2016; 8: 86.
    • (2016) Nutrients , vol.8 , pp. 86
    • Jackson, P.A.1    Forster, J.S.2    Bell, J.G.3    Dick, J.R.4    Younger, I.5    Kennedy, D.O.6
  • 42
    • 84869449674 scopus 로고    scopus 로고
    • Effect of altering dietary n-6:n-3 PUFA ratio on cardiovascular risk measures in patients treated with statins: A pilot study
    • Lee SP, Dart AM, Walker KZ, O'Dea K, Chin-Dusting JP, Skilton MR. Effect of altering dietary n-6:n-3 PUFA ratio on cardiovascular risk measures in patients treated with statins: a pilot study. Br J Nutr 2012; 108(7): 1280-5.
    • (2012) Br J Nutr , vol.108 , Issue.7 , pp. 1280-1285
    • Lee, S.P.1    Dart, A.M.2    Walker, K.Z.3    O'Dea, K.4    Chin-Dusting, J.P.5    Skilton, M.R.6
  • 45
    • 78049528932 scopus 로고    scopus 로고
    • Beneficial effects of docosahexaenoic acid on cognition in age-related cognitive decline
    • Yurko-Mauro K, McCarthy D, Rom D, Nelson EB, Ryan AS, Blackwell A, et al. Beneficial effects of docosahexaenoic acid on cognition in age-related cognitive decline. Alzheimer's Dement 2010; 6(6): 456-64.
    • (2010) Alzheimer's Dement , vol.6 , Issue.6 , pp. 456-464
    • Yurko-Mauro, K.1    McCarthy, D.2    Rom, D.3    Nelson, E.B.4    Ryan, A.S.5    Blackwell, A.6
  • 46
    • 85011416514 scopus 로고    scopus 로고
    • Effect of ω-3 polyunsaturated fatty acids in young people at ultrahigh risk for psychotic disorders: The NEURAPRO randomized clinical trial
    • McGorry PD, Nelson B, Markulev C, Yuen HP, Schäfer MR, Mossaheb N, et al. Effect of ω-3 polyunsaturated fatty acids in young people at ultrahigh risk for psychotic disorders: the NEURAPRO randomized clinical trial. JAMA Psychiatry 2017; 74(1): 19-27.
    • (2017) JAMA Psychiatry , vol.74 , Issue.1 , pp. 19-27
    • McGorry, P.D.1    Nelson, B.2    Markulev, C.3    Yuen, H.P.4    Schäfer, M.R.5    Mossaheb, N.6
  • 47
    • 84865643296 scopus 로고    scopus 로고
    • Omega-3 fatty acid treatment in multiple sclerosis (OFAMS study): A randomized, double-blind, placebo-controlled trial
    • Torkildsen O, Wergeland S, Bakke S, Beiske AG, Bjerve KS, Hovdal H, et al. Omega-3 fatty acid treatment in multiple sclerosis (OFAMS study): a randomized, double-blind, placebo-controlled trial. Arch Neurol 2012; 69(8): 1044-51.
    • (2012) Arch Neurol , vol.69 , Issue.8 , pp. 1044-1051
    • Torkildsen, O.1    Wergeland, S.2    Bakke, S.3    Beiske, A.G.4    Bjerve, K.S.5    Hovdal, H.6
  • 48
    • 84959011001 scopus 로고    scopus 로고
    • A randomized controlled study of the efficacy of six-month supplementation with concentrated fish oil rich in omega-3 polyunsaturated fatty acids in first episode schizophrenia
    • Pawelczyk T, Grancow-Grabka M, Kotlicka-Antczak M, Trafalska E, Pawelczyk A. A randomized controlled study of the efficacy of six-month supplementation with concentrated fish oil rich in omega-3 polyunsaturated fatty acids in first episode schizophrenia. J Psychiatr Res 2016; 73: 34-44.
    • (2016) J Psychiatr Res , vol.73 , pp. 34-44
    • Pawelczyk, T.1    Grancow-Grabka, M.2    Kotlicka-Antczak, M.3    Trafalska, E.4    Pawelczyk, A.5
  • 49
    • 39749095115 scopus 로고    scopus 로고
    • Omega-3 supplementation in mild to moderate Alzheimer's disease: Effects on neuropsychiatric symptoms
    • Freund-Levi Y, Basun H, Cederholm T, Faxen-Irving G, Garlind A, Grut M, et al. Omega-3 supplementation in mild to moderate Alzheimer's disease: effects on neuropsychiatric symptoms. Int J Geriatr Psychiatry 2008; 23(2): 161-9.
    • (2008) Int J Geriatr Psychiatry , vol.23 , Issue.2 , pp. 161-169
    • Freund-Levi, Y.1    Basun, H.2    Cederholm, T.3    Faxen-Irving, G.4    Garlind, A.5    Grut, M.6
  • 50
    • 78650169331 scopus 로고    scopus 로고
    • OMEGA, a randomized, placebo-controlled trial to test the effect of highly purified omega-3 fatty acids on top of modern guideline-adjusted therapy after myocardial infarction
    • Rauch B, Schiele R, Schneider S, Diller F, Victor N, Gohlke H, et al. OMEGA, a randomized, placebo-controlled trial to test the effect of highly purified omega-3 fatty acids on top of modern guideline-adjusted therapy after myocardial infarction. Circulation 2010; 122(21): 2152-9.
    • (2010) Circulation , vol.122 , Issue.21 , pp. 2152-2159
    • Rauch, B.1    Schiele, R.2    Schneider, S.3    Diller, F.4    Victor, N.5    Gohlke, H.6
  • 51
    • 77953066352 scopus 로고    scopus 로고
    • Effect of 2-y n-3 long-chain polyunsaturated fatty acid supplementation on cognitive function in older people: A randomized, double-blind, controlled trial
    • Dangour AD, Allen E, Elbourne D, Fasey N, Fletcher AE, Hardy P, et al. Effect of 2-y n-3 long-chain polyunsaturated fatty acid supplementation on cognitive function in older people: a randomized, double-blind, controlled trial. Am J Clin Nutr 2010; 91(6): 1725-32.
    • (2010) Am J Clin Nutr , vol.91 , Issue.6 , pp. 1725-1732
    • Dangour, A.D.1    Allen, E.2    Elbourne, D.3    Fasey, N.4    Fletcher, A.E.5    Hardy, P.6
  • 52
    • 85101535671 scopus 로고    scopus 로고
    • Omega 3 fatty acids supplementation in Schizophrenia
    • Palma C. Omega 3 fatty acids supplementation in Schizophrenia. Eur Arch Psychiatry Clin Neurosci 2015; 265(Suppl 1): S122-S.
    • (2015) Eur Arch Psychiatry Clin Neurosci , vol.265 , pp. S122
    • Palma, C.1
  • 54
    • 67650567090 scopus 로고    scopus 로고
    • Efficacy and safety of prescription omega-3-acid ethyl esters for the prevention of recurrent symptomatic atrial fibrillation: A prospective study
    • Pratt CM, Reiffel JA, Ellenbogen KA, Naccarelli GV, Kowey PR. Efficacy and safety of prescription omega-3-acid ethyl esters for the prevention of recurrent symptomatic atrial fibrillation: a prospective study. Am Heart J 2009; 158(2): 163-9.
    • (2009) Am Heart J , vol.158 , Issue.2 , pp. 163-169
    • Pratt, C.M.1    Reiffel, J.A.2    Ellenbogen, K.A.3    Naccarelli, G.V.4    Kowey, P.R.5
  • 55
    • 84950170862 scopus 로고    scopus 로고
    • Effects of n-3 fatty acids, EPA v. DHA, on depressive symptoms, quality of life, memory and executive function in older adults with mild cognitive impairment: A 6-month randomised controlled trial
    • Sinn N, Milte CM, Street SJ, Buckley JD, Coates AM, Petkov J, et al. Effects of n-3 fatty acids, EPA v. DHA, on depressive symptoms, quality of life, memory and executive function in older adults with mild cognitive impairment: a 6-month randomised controlled trial. Br J Nutr2012; 107(11): 1682-93.
    • Br J Nutr2012 , vol.107 , Issue.11 , pp. 1682-1693
    • Sinn, N.1    Milte, C.M.2    Street, S.J.3    Buckley, J.D.4    Coates, A.M.5    Petkov, J.6
  • 56
    • 79551499975 scopus 로고    scopus 로고
    • Effects of B vitamins and omega 3 fatty acids on cardiovascular diseases: A randomised placebo controlled trial
    • Galan P, Kesse-Guyot E, Czernichow S, Briancon S, Blacher J, Hercberg S, et al. Effects of B vitamins and omega 3 fatty acids on cardiovascular diseases: a randomised placebo controlled trial. BMJ 2010; 341: c6273.
    • (2010) BMJ , vol.341 , pp. c6273
    • Galan, P.1    Kesse-Guyot, E.2    Czernichow, S.3    Briancon, S.4    Blacher, J.5    Hercberg, S.6
  • 57
    • 44649129433 scopus 로고    scopus 로고
    • Comparison of low-fat versus Mediterranean-style dietary intervention after first myocardial infarction (from the Heart Institute of Spokane Diet Intervention and Evaluation Trial)
    • Tuttle KR, Shuler LA, Packard DP, Milton JE, Daratha KB, Bibus DM, et al. Comparison of low-fat versus Mediterranean-style dietary intervention after first myocardial infarction (from The Heart Institute of Spokane Diet Intervention and Evaluation Trial). Am J Cardiol 2008; 101(11): 1523-30.
    • (2008) Am J Cardiol , vol.101 , Issue.11 , pp. 1523-1530
    • Tuttle, K.R.1    Shuler, L.A.2    Packard, D.P.3    Milton, J.E.4    Daratha, K.B.5    Bibus, D.M.6
  • 58
    • 61449249687 scopus 로고    scopus 로고
    • Randomized controlled trial of ethyl-eicosapentaenoic acid in Huntington disease: The TREND-HD study
    • Huntington Study Group.
    • Huntington Study Group. Randomized controlled trial of ethyl-eicosapentaenoic acid in Huntington disease: the TREND-HD study. Arch Neurol 2008; 65(12): 1582-9.
    • (2008) Arch Neurol , vol.65 , Issue.12 , pp. 1582-1589
  • 59
    • 85055022100 scopus 로고    scopus 로고
    • Effects of n-3 fatty acid supplements in diabetes mellitus
    • ASCEND Study Collaborative Group.
    • ASCEND Study Collaborative Group. Effects of n-3 fatty acid supplements in diabetes mellitus. N Engl J Med 2018; 379(16): 1540-50.
    • (2018) N Engl J Med , vol.379 , Issue.16 , pp. 1540-1550
  • 60
    • 85016730734 scopus 로고    scopus 로고
    • Effect of long-term omega 3 polyunsaturated fatty acid supplementation with or without multidomain intervention on cognitive function in elderly adults with memory complaints (MAPT): A randomised, placebo-controlled trial
    • Andrieu S, Guyonnet S, Coley N, Cantet C, Bonnefoy M, Bordes S, et al. Effect of long-term omega 3 polyunsaturated fatty acid supplementation with or without multidomain intervention on cognitive function in elderly adults with memory complaints (MAPT): a randomised, placebo-controlled trial. Lancet Neurol 2017; 16(5): 377-89.
    • (2017) Lancet Neurol , vol.16 , Issue.5 , pp. 377-389
    • Andrieu, S.1    Guyonnet, S.2    Coley, N.3    Cantet, C.4    Bonnefoy, M.5    Bordes, S.6
  • 61
    • 51749101160 scopus 로고    scopus 로고
    • Effect of fish-oil supplementation on mental well-being in older subjects: A randomized, double-blind, placebo-controlled trial
    • Van De Rest O, Geleijnse JM, Kok FJ, van Staveren WA, Hoefnagels WH, Beekman AT, et al. Effect of fish-oil supplementation on mental well-being in older subjects: a randomized, double-blind, placebo-controlled trial. Am J Clin Nutr 2008; 88(3): 706-13.
    • (2008) Am J Clin Nutr , vol.88 , Issue.3 , pp. 706-713
    • Van De Rest, O.1    Geleijnse, J.M.2    Kok, F.J.3    Van Staveren, W.A.4    Hoefnagels, W.H.5    Beekman, A.T.6
  • 62
    • 84875787136 scopus 로고    scopus 로고
    • Retraction and republication: Primary prevention of cardiovascular disease with a Mediterranean diet
    • N Engl J Med 2018; 378: 2441-2
    • Estruch R, Ros E, Salas-Salvadó J, Covas M, Corella D, Arós F, et al. Retraction and republication: primary prevention of cardiovascular disease with a Mediterranean diet. N Engl J Med 2013;368:1279-90. N Engl J Med 2018; 378: 2441-2.
    • (2013) N Engl J Med , vol.368 , pp. 1279-1290
    • Estruch, R.1    Ros, E.2    Salas-Salvadó, J.3    Covas, M.4    Corella, D.5    Arós, F.6
  • 63
    • 85062337400 scopus 로고    scopus 로고
    • Effect of multinutrient supplementation and food-related behavioral activation therapy on prevention of major depressive disorder among overweight or obese adults with subsyndromal depressive symptoms: The MooDFOOD randomized clinical trial
    • Bot M, Brouwer IA, Roca M, Kohls E, Penninx BWJH, Watkins E, et al. Effect of multinutrient supplementation and food-related behavioral activation therapy on prevention of major depressive disorder among overweight or obese adults with subsyndromal depressive symptoms: the MooDFOOD randomized clinical trial. JAMA 2019; 321(9): 858-68.
    • (2019) JAMA , vol.321 , Issue.9 , pp. 858-868
    • Bot, M.1    Brouwer, I.A.2    Roca, M.3    Kohls, E.4    Bwjh, P.5    Watkins, E.6
  • 64
    • 85058154684 scopus 로고    scopus 로고
    • Association of use of omega-3 polyunsaturated fatty acids with changes in severity of anxiety symptoms: A systematic review and meta-analysis
    • Su K-P, Tseng P-T, Lin P-Y, Okubo R, Chen T-Y, Chen Y-W, et al. Association of use of omega-3 polyunsaturated fatty acids with changes in severity of anxiety symptoms: a systematic review and meta-analysis. JAMA Netw Open 2018; 1(5): e182327.
    • (2018) JAMA Netw Open , vol.1 , Issue.5 , pp. e182327
    • Su, K.-P.1    Tseng, P.-T.2    Lin, P.-Y.3    Okubo, R.4    Chen, T.-Y.5    Chen, Y.-W.6
  • 65
    • 84977128122 scopus 로고    scopus 로고
    • Meta-analysis and meta-regression of omega-3 polyunsaturated fatty acid supplementation for major depressive disorder
    • Mocking RJ, Harmsen I, Assies J, KoeterMW, Ruhe HG, Schene AH.Meta-analysis and meta-regression of omega-3 polyunsaturated fatty acid supplementation for major depressive disorder. Transl Psychiatry 2016; 6: e756.
    • (2016) Transl Psychiatry , vol.6 , pp. e756
    • Mocking, R.J.1    Harmsen, I.2    Assies, J.3    Koeter, M.W.4    Ruhe, H.G.5    Schene, A.H.6
  • 66
    • 85051680527 scopus 로고    scopus 로고
    • Omega-3 polyunsaturated fatty acids and reduction of depressive symptoms in older adults: A systematic review and meta-analysis
    • Bai Z-G, Bo A, Wu S-J, Gai Q-Y, Chi I. Omega-3 polyunsaturated fatty acids and reduction of depressive symptoms in older adults: a systematic review and meta-analysis. J Affect Disord 2018; 241: 241-8.
    • (2018) J Affect Disord , vol.241 , pp. 241-248
    • Bai, Z.-G.1    Bo, A.2    Wu, S.-J.3    Gai, Q.-Y.4    Chi, I.5
  • 67
    • 84988876983 scopus 로고    scopus 로고
    • Efficacy of omega-3 highly unsaturated fatty acids in the treatment of depression
    • Hallahan B, Ryan T, Hibbeln JR, Murray IT, Glynn S, Ramsden CE, et al. Efficacy of omega-3 highly unsaturated fatty acids in the treatment of depression. Br J Psychiatry 2018; 209(3): 192-201.
    • (2018) Br J Psychiatry , vol.209 , Issue.3 , pp. 192-201
    • Hallahan, B.1    Ryan, T.2    Hibbeln, J.R.3    Murray, I.T.4    Glynn, S.5    Ramsden, C.E.6
  • 68
    • 84939237901 scopus 로고    scopus 로고
    • Combined application of eicosapentaenoic acid and docosahexaenoic acid on depression in women: A meta-analysis of double-blind randomized controlled trials
    • Yang JR, Han D, Qiao ZX, Tian X, Qi D, Qiu XH. Combined application of eicosapentaenoic acid and docosahexaenoic acid on depression in women: a meta-analysis of double-blind randomized controlled trials. Neuropsychiatr 2015; 11: 2055-61.
    • (2015) Neuropsychiatr , vol.11 , pp. 2055-2061
    • Yang, J.R.1    Han, D.2    Qiao, Z.X.3    Tian, X.4    Qi, D.5    Qiu, X.H.6
  • 69
    • 84861170177 scopus 로고    scopus 로고
    • Effects of n-3 fatty acids on cognitive decline: A randomized double-blind, placebo-controlled trial in stable myocardial infarction patients
    • Geleijnse J, Giltay E, Kromhout D. Effects of n-3 fatty acids on cognitive decline: a randomized double-blind, placebo-controlled trial in stable myocardial infarction patients. Alzheimer's Dement 2011; 1: S512.
    • (2011) Alzheimer's Dement , vol.1 , pp. S512
    • Geleijnse, J.1    Giltay, E.2    Kromhout, D.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.