Spike protein recognition of mammalian ACE2 predicts the host range and an optimized ACE2 for SARS-CoV-2 infection

Biochemical and Biophysical Research Communications

Volumn 526, Issue 1, 2020, Pages 165-169

  Luan, Junwen ^a   Lu, Yue ^a   Jin, Xiaolu ^a   Zhang, Leiliang ^a  

^a SHANDONG PROVINCIAL HOSPITAL AFFILIATED TO SHANDONG FIRST MEDICAL UNIVERSITY   (China)

Author keywords

ACE2; Host range; SARS CoV 2; Spike protein; Structure

Indexed keywords

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CAT; CHINESE HAMSTER; CORONAVIRUS DISEASE 2019; DOG; HOST RANGE; HUMAN; MOLECULAR RECOGNITION; NONHUMAN; PHOLIDOTA (ANIMAL); SARS CORONAVIRUS; SEVERE ACUTE RESPIRATORY SYNDROME CORONAVIRUS 2; SIMULATION; SPIKE; AMINO ACID SEQUENCE; ANIMAL; BETACORONAVIRUS; CHEMISTRY; CLASSIFICATION; CORONAVIRUS INFECTION; MAMMAL; METABOLISM; MOLECULAR MODEL; PANDEMIC; PHYSIOLOGY; SEQUENCE ALIGNMENT; VIRAL TROPISM; VIROLOGY; VIRUS PNEUMONIA;

ANGIOTENSIN CONVERTING ENZYME 2; CORONAVIRUS SPIKE GLYCOPROTEIN; DIPEPTIDYL CARBOXYPEPTIDASE; SPIKE PROTEIN, SARS-COV-2;

AMINO ACID SEQUENCE; ANIMALS; BETACORONAVIRUS; CORONAVIRUS INFECTIONS; HUMANS; MAMMALS; MODELS, MOLECULAR; PANDEMICS; PEPTIDYL-DIPEPTIDASE A; PNEUMONIA, VIRAL; SEQUENCE ALIGNMENT; SPIKE GLYCOPROTEIN, CORONAVIRUS; VIRAL TROPISM;

EID: 85081948208     PISSN: 0006291X     EISSN: 10902104     Source Type: Journal    
DOI: 10.1016/j.bbrc.2020.03.047     Document Type: Article

References (20)

1. Zhu, N., Zhang, D., Wang, W., Li, X., Yang, B., Song, J., Zhao, X., Huang, B., Shi, W., Lu, R., Niu, P., Zhan, F., Ma, X., Wang, D., Xu, W., Wu, G., Gao, G.F., Tan, W., A novel coronavirus from patients with pneumonia in China, 2019. N. Engl. J. Med. 382 (2020), 727–733.
2. Wu, F., Zhao, S., Yu, B., Chen, Y.M., Wang, W., Song, Z.G., Hu, Y., Tao, Z.W., Tian, J.H., Pei, Y.Y., Yuan, M.L., Zhang, Y.L., Dai, F.H., Liu, Y., Wang, Q.M., Zheng, J.J., Xu, L., Holmes, E.C., Zhang, Y.Z., A new coronavirus associated with human respiratory disease in China. Nature 579 (2020), 265–269.
3. Zhou, P., Yang, X.L., Wang, X.G., Hu, B., Zhang, L., Zhang, W., Si, H.R., Zhu, Y., Li, B., Huang, C.L., Chen, H.D., Chen, J., Luo, Y., Guo, H., Jiang, R.D., Liu, M.Q., Chen, Y., Shen, X.R., Wang, X., Zheng, X.S., Zhao, K., Chen, Q.J., Deng, F., Liu, L.L., Yan, B., Zhan, F.X., Wang, Y.Y., Xiao, G.F., Shi, Z.L., A pneumonia outbreak associated with a new coronavirus of probable bat origin. Nature 579 (2020), 270–273.
4. Zhong, N.S., Zheng, B.J., Li, Y.M., Poon, Xie, Z.H., Chan, K.H., Li, P.H., Tan, S.Y., Chang, Q., Xie, J.P., Liu, X.Q., Xu, J., Li, D.X., Yuen, K.Y., Peiris, Guan, Y., Epidemiology and cause of severe acute respiratory syndrome (SARS) in Guangdong, People's Republic of China. Lancet 362 (2003), 1353–1358.
5. Zaki, A.M., van Boheemen, S., Bestebroer, T.M., Osterhaus, A.D., Fouchier, R.A., Isolation of a novel coronavirus from a man with pneumonia in Saudi Arabia. N. Engl. J. Med. 367 (2012), 1814–1820.
6. Wu, A., Peng, Y., Huang, B., Ding, X., Wang, X., Niu, P., Meng, J., Zhu, Z., Zhang, Z., Wang, J., Sheng, J., Quan, L., Xia, Z., Tan, W., Cheng, G., Jiang, T., Genome composition and divergence of the novel coronavirus (2019-nCoV) originating in China. Cell Host Microbe 27 (2020), 325–328.
7. Li, F., Li, W., Farzan, M., Harrison, S.C., Structure of SARS coronavirus spike receptor-binding domain complexed with receptor. Science 309 (2005), 1864–1868.
8. Li, W., Moore, M.J., Vasilieva, N., Sui, J., Wong, S.K., Berne, M.A., Somasundaran, M., Sullivan, J.L., Luzuriaga, K., Greenough, T.C., Choe, H., Farzan, M., Angiotensin-converting enzyme 2 is a functional receptor for the SARS coronavirus. Nature 426 (2003), 450–454.
9. Anguiano, L., Riera, M., Pascual, J., Soler, M.J., Circulating ACE2 in cardiovascular and kidney diseases. Curr. Med. Chem. 24 (2017), 3231–3241.
10. Letko, M., Marzi, A., Munster, V., Functional assessment of cell entry and receptor usage for SARS-CoV-2 and other lineage B betacoronavirus. Nat Microbiol., 2020, 10.1038/s41564-020-0688-y.
11. Wong, M.C., Cregeen, S.J.J., Ajami, N.J., Petrosino, J.F., Evidence of recombination in coronaviruses implicating pangolin origins of nCoV-2019. bioRxiv, 2020, 2020.02.07.939207.
12. Lam, T.T.-Y., Shum, M.H.-H., Zhu, H.-C., Tong, Y.-G., Ni, X.-B., Liao, Y.-S., Wei, W., Cheung, W.Y.-M., Li, W.-J., Li, L.-F., Leung, G.M., Holmes, E.C., Hu, Y.-L., Guan, Y., Identification of 2019-nCoV related coronaviruses in Malayan pangolins in southern China. bioRxiv, 2020 2002.2013.945485.
13. Kumar, S., Stecher, G., Li, M., Knyaz, C., Tamura, K., Mega, X., Molecular evolutionary genetics analysis across computing platforms. Mol. Biol. Evol. 35 (2018), 1547–1549.
14. Pettersen, E.F., Goddard, T.D., Huang, C.C., Couch, G.S., Greenblatt, D.M., Meng, E.C., Ferrin, T.E., UCSF Chimera-a visualization system for exploratory research and analysis. J. Comput. Chem. 25 (2004), 1605–1612.
15. Wan, Y., Shang, J., Graham, R., Baric, R.S., Li, F., Receptor recognition by novel coronavirus from Wuhan: an analysis based on decade-long structural studies of SARS. J. Virol., 2020 pii: JVI.00127-20.
16. Yan, R., Zhang, Y., Guo, Y., Xia, L., Zhou, Q., Structural basis for the recognition of the 2019-nCoV by human ACE2. bioRxiv, 2020 2002.2019.956946.
17. Lan, J., Ge, J., Yu, J., Shan, S., Zhou, H., Fan, S., Zhang, Q., Shi, X., Wang, Q., Zhang, L., Wang, X., Crystal structure of the 2019-nCoV spike receptor-binding domain bound with the ACE2 receptor. bioRxiv, 2020 2002.2019.956235.
18. Kan, B., Wang, M., Jing, H., Xu, H., Jiang, X., Yan, M., Liang, W., Zheng, H., Wan, K., Liu, Q., Cui, B., Xu, Y., Zhang, E., Wang, H., Ye, J., Li, G., Li, M., Cui, Z., Qi, X., Chen, K., Du, L., Gao, K., Zhao, Y.T., Zou, X.Z., Feng, Y.J., Gao, Y.F., Hai, R., Yu, D., Guan, Y., Xu, J., Molecular evolution analysis and geographic investigation of severe acute respiratory syndrome coronavirus-like virus in palm civets at an animal market and on farms. J. Virol. 79 (2005), 11892–11900.
19. Chan, R.W., Hemida, M.G., Kayali, G., Chu, D.K., Poon, L.L., Alnaeem, A., Ali, M.A., Tao, K.P., Ng, H.Y., Chan, M.C., Guan, Y., Nicholls, J.M., Peiris, J.S., Tropism and replication of Middle East respiratory syndrome coronavirus from dromedary camels in the human respiratory tract: an in-vitro and ex-vivo study. Lancet Respir Med 2 (2014), 813–822.
20. Yang, X.H., Deng, W., Tong, Z., Liu, Y.X., Zhang, L.F., Zhu, H., Gao, H., Huang, L., Liu, Y.L., Ma, C.M., Xu, Y.F., Ding, M.X., Deng, H.K., Qin, C., Mice transgenic for human angiotensin-converting enzyme 2 provide a model for SARS coronavirus infection. Comp. Med. 57 (2007), 450–459.