Fungal highly reducing polyketide synthases biosynthesize salicylaldehydes that are precursors to epoxycyclohexenol natural products

Journal of the American Chemical Society

Volumn 141, Issue 50, 2019, Pages 19538-19541

  Liu, Ling ^a,b   Tang, Man Cheng ^a   Tang, Yi ^a,c  

^a University of California   (United States)

^b INSTITUTE OF MICROBIOLOGY   (China)

^c UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BIOCHEMISTRY; BIOSYNTHESIS; CONDENSATION REACTIONS; DEHYDROGENATION; ENZYMES; GENES;

ALDOL CONDENSATION; BIOSYNTHETIC GENE CLUSTER; MULTI-DOMAIN ENZYMES; NATURAL PRODUCTS; POLYKETIDE STRUCTURE; POLYKETIDE SYNTHASES; SALICYL ALDEHYDE; TRICHODERMA VIRENS;

KETONES;

EPOXYCYCLOHEXENOL; FUNGAL ENZYME; HIGHLY REDUCING POLYKETIDE SYNTHASE; HYDROXYL GROUP; KETONE; NATURAL PRODUCT; OXIDOREDUCTASE; POLYKETIDE SYNTHASE; SALICYLALDEHYDE; UNCLASSIFIED DRUG; ALDEHYDE; BIOLOGICAL PRODUCT; EPOXIDE;

ALDOL REACTION; AROMATIZATION; ARTICLE; BIOSYNTHESIS; CONTROLLED STUDY; DEHYDROGENATION; ENZYMATIC ASSAY; EPOXIDATION; GENE CLUSTER; HYDROXYLATION; NONHUMAN; STEREOCHEMISTRY; CHEMISTRY; ENZYMOLOGY; METABOLISM; OXIDATION REDUCTION REACTION; TRICHODERMA;

ALDEHYDES; BIOLOGICAL PRODUCTS; EPOXY COMPOUNDS; OXIDATION-REDUCTION; POLYKETIDE SYNTHASES; TRICHODERMA;

EID: 85076251225     PISSN: 00027863     EISSN: 15205126     Source Type: Journal    
DOI: 10.1021/jacs.9b09669     Document Type: Article

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