A Single-Stranded Oligonucleotide Inhibits Toll-Like Receptor 3 Activation and Reduces Influenza A (H1N1) Infection

Frontiers in Immunology

Volumn 10, Issue , 2019, Pages

  Poux, Candice ^a   Dondalska, Aleksandra ^a   Bergenstråhle, Joseph ^b   Pålsson, Sandra ^a   Contreras, Vanessa ^c   Arasa, Claudia ^a   Järver, Peter ^a   Albert, Jan ^d,e   Busse, David C ^f   LeGrand, Roger ^c   Lundeberg, Joakim ^b   Tregoning, John S ^f   Spetz, Anna Lena ^a  

^a STOCKHOLM UNIVERSITY   (Sweden)

^b ROYAL INSTITUTE OF TECHNOLOGY   (Sweden)

^c INSTITUT DE RADIOPROTECTION ET DE SÛRETÉ NUCLÉAIRE   (France)

^d KAROLINSKA INSTITUTE   (Sweden)

^e KAROLINSKA UNIVERSITY HOSPITAL   (Sweden)

^f IMPERIAL COLLEGE LONDON   (United Kingdom)

Author keywords

clathrin mediated endocytosis; co stimulatory molecules; cytokines; human monocyte derived dendritic cells (MoDC); influenza A; mice; single stranded oligonucleotides; TLR3

Indexed keywords

ALPHA INTERFERON; ANTIVIRUS AGENT; B7 ANTIGEN; CD86 ANTIGEN; CRYOPYRIN; INFLAMMASOME; INITIATION FACTOR 2; INTERFERON; INTERLEUKIN 12; INTERLEUKIN 23; INTERLEUKIN 29; INTERLEUKIN 6; LIGAND; OLIGONUCLEOTIDE; PATTERN RECOGNITION RECEPTOR; PHOSPHOLIPASE C; SINGLE STRANDED OLIGONUCLEOTIDE; TOLL LIKE RECEPTOR 3; TOLL LIKE RECEPTOR AGONIST; TRANSCRIPTION FACTOR; TUMOR NECROSIS FACTOR; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTIVIRAL ACTIVITY; ARTICLE; CELL VIABILITY; CONTROLLED STUDY; CYTOKINE RESPONSE; DENDRITIC CELL; DOUBLE-STRANDED RNA VIRUS; ENDOCYTOSIS; ENZYME LINKED IMMUNOSORBENT ASSAY; FEMALE; FLOW CYTOMETRY; FLUORESCENCE IMAGING; GENE EXPRESSION; INFLUENZA A (H1N1); INFLUENZA A VIRUS; LUNG LAVAGE; MOUSE; NATURAL KILLER CELL; NONHUMAN; OXIDATIVE PHOSPHORYLATION; PROTEIN EXPRESSION; REAL TIME POLYMERASE CHAIN REACTION; RNA EXTRACTION; SEQUENCE ANALYSIS; T LYMPHOCYTE; TRANSCRIPTOMICS; TREATMENT OUTCOME; UPREGULATION; VIRUS LOAD; ANIMAL; BAGG ALBINO MOUSE; CYTOLOGY; DOG; HUMAN; IMMUNOLOGY; INFLUENZA A VIRUS (H1N1); MDCK CELL LINE; MONOCYTE; ORTHOMYXOVIRUS INFECTION; VIROLOGY;

ANIMALS; DENDRITIC CELLS; DOGS; FEMALE; HUMANS; INFLUENZA A VIRUS, H1N1 SUBTYPE; MADIN DARBY CANINE KIDNEY CELLS; MICE, INBRED BALB C; MONOCYTES; OLIGONUCLEOTIDES; ORTHOMYXOVIRIDAE INFECTIONS; TOLL-LIKE RECEPTOR 3;

EID: 85072762910     PISSN: None     EISSN: 16643224     Source Type: Journal    
DOI: 10.3389/fimmu.2019.02161     Document Type: Article

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