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Volumn 10, Issue JULY, 2019, Pages

Major effect of oxidative stress on the Male, but not female, SP-A1 type II cell miRNome

Author keywords

Alveolar epithelium; MAPK; Ozone; Sex differences; Surfactant protein A

Indexed keywords

ARGONAUTE 2 PROTEIN; CYCLIN D1; DEAD BOX PROTEIN 20; INSULIN RECEPTOR SUBSTRATE 1; JANUS KINASE 2; MESSENGER RNA; MICRORNA; MITOGEN ACTIVATED PROTEIN KINASE 1; PHOSPHOLIPASE C GAMMA2; PROTEIN BCL 2; SURFACTANT PROTEIN A; SURFACTANT PROTEIN A1; SURFACTANT PROTEIN A2; UNCLASSIFIED DRUG; VON HIPPEL LINDAU PROTEIN; AGO2 PROTEIN, MOUSE; ARGONAUTE PROTEIN; INSULIN RECEPTOR SUBSTRATE; IRS1 PROTEIN, MOUSE; SEX HORMONE; VHL PROTEIN, MOUSE;

EID: 85069448094     PISSN: None     EISSN: 16643224     Source Type: Journal    
DOI: 10.3389/fimmu.2019.01514     Document Type: Article
Times cited : (15)

References (65)
  • 1
    • 84884306282 scopus 로고    scopus 로고
    • Reactive oxygen species in chronic rhinosinusitis and secondhand smoke exposure
    • PubMed Abstract | CrossRef Full Text | Google Scholar
    • Fordham MT, Mulligan JK, Casey SE, Mulligan RM, Wang EW, Sansoni ER, et al. Reactive oxygen species in chronic rhinosinusitis and secondhand smoke exposure. Otolaryngol Head Neck Surg. (2013) 149:633–8. doi: 10.1177/0194599813496377 PubMed Abstract | CrossRef Full Text | Google Scholar
    • (2013) Otolaryngol Head Neck Surg , vol.149 , pp. 633-638
    • Fordham, M.T.1    Mulligan, J.K.2    Casey, S.E.3    Mulligan, R.M.4    Wang, E.W.5    Sansoni, E.R.6
  • 2
    • 79952694437 scopus 로고    scopus 로고
    • Ambient ozone and pulmonary innate immunity
    • PubMed Abstract | CrossRef Full Text | Google Scholar
    • Al-Hegelan M, Tighe RM, Castillo C, Hollingsworth JW. Ambient ozone and pulmonary innate immunity. Immunol Res. (2011) 49:173–91. doi: 10.1007/s12026-010-8180-z PubMed Abstract | CrossRef Full Text | Google Scholar
    • (2011) Immunol Res , vol.49 , pp. 173-191
    • Al-Hegelan, M.1    Tighe, R.M.2    Castillo, C.3    Hollingsworth, J.W.4
  • 3
    • 84892561027 scopus 로고    scopus 로고
    • Oxidative stress in airway diseases
    • PubMed Abstract | CrossRef Full Text | Google Scholar
    • Holguin F. Oxidative stress in airway diseases. Ann Am Thorac Soc. (2013) 10(Suppl.):S150–7. doi: 10.1513/AnnalsATS.201305-116AW PubMed Abstract | CrossRef Full Text | Google Scholar
    • (2013) Ann Am Thorac Soc , vol.10 , pp. S150-S157
    • Holguin, F.1
  • 4
    • 84926637156 scopus 로고    scopus 로고
    • Respiratory epithelial cells orchestrate pulmonary innate immunity
    • PubMed Abstract | CrossRef Full Text | Google Scholar
    • Whitsett JA, Alenghat T. Respiratory epithelial cells orchestrate pulmonary innate immunity. Nat Immunol. (2015) 16:27–35. doi: 10.1038/ni.3045 PubMed Abstract | CrossRef Full Text | Google Scholar
    • (2015) Nat Immunol , vol.16 , pp. 27-35
    • Whitsett, J.A.1    Alenghat, T.2
  • 5
    • 84932109050 scopus 로고    scopus 로고
    • Respiratory protease/antiprotease balance determines susceptibility to viral infection and can be modified by nutritional antioxidants
    • PubMed Abstract | CrossRef Full Text | Google Scholar
    • Meyer M, Jaspers I. Respiratory protease/antiprotease balance determines susceptibility to viral infection and can be modified by nutritional antioxidants. Am J Physiol Lung Cell Mol Physiol. (2015) 308:L1189–201. doi: 10.1152/ajplung.00028.2015 PubMed Abstract | CrossRef Full Text | Google Scholar
    • (2015) Am J Physiol Lung Cell Mol Physiol , vol.308 , pp. L1189-L1201
    • Meyer, M.1    Jaspers, I.2
  • 6
    • 0034956518 scopus 로고    scopus 로고
    • Ozone exposure and the production of reactive oxygen species by bronchoalveolar cells in humans
    • PubMed Abstract | CrossRef Full Text | Google Scholar
    • Voter KZ, Whitin JC, Torres A, Morrow PE, Cox C, Tsai Y, et al. Ozone exposure and the production of reactive oxygen species by bronchoalveolar cells in humans. Inhal Toxicol. (2001) 13:465–83. doi: 10.1080/08958370151131837 PubMed Abstract | CrossRef Full Text | Google Scholar
    • (2001) Inhal Toxicol , vol.13 , pp. 465-483
    • Voter, K.Z.1    Whitin, J.C.2    Torres, A.3    Morrow, P.E.4    Cox, C.5    Tsai, Y.6
  • 7
    • 84994430911 scopus 로고    scopus 로고
    • Reactive oxygen species/hypoxia-inducible factor-1α/platelet-derived growth factor-BB autocrine loop contributes to cocaine-mediated alveolar epithelial barrier damage
    • PubMed Abstract | CrossRef Full Text |
    • Yang L, Chen X, Simet SM, Hu G, Cai Y, Niu F, et al. Reactive oxygen species/hypoxia-inducible factor-1α/platelet-derived growth factor-BB autocrine loop contributes to cocaine-mediated alveolar epithelial barrier damage. Am J Respir Cell Mol Biol. (2016) 55:736–48. doi: 10.1165/rcmb.2016-0096OC PubMed Abstract | CrossRef Full Text |
    • (2016) Am J Respir Cell Mol Biol , vol.55 , pp. 736-748
    • Yang, L.1    Chen, X.2    Simet, S.M.3    Hu, G.4    Cai, Y.5    Niu, F.6
  • 8
    • 0028079226 scopus 로고
    • Are changes in breathing pattern on exposure to ozone related to changes in pulmonary surfactant?
    • CrossRef Full Text | Google Scholar
    • Finlayson-pitts BJ, Mautz WJ, Lai CC, Bufalino C, Messer K, Mestas J, et al. Are changes in breathing pattern on exposure to ozone related to changes in pulmonary surfactant? Inhal Toxicol. (1994) 6:267–87. doi: 10.3109/08958379408995236 CrossRef Full Text | Google Scholar
    • (1994) Inhal Toxicol , vol.6 , pp. 267-287
    • Finlayson-Pitts, B.J.1    Mautz, W.J.2    Lai, C.C.3    Bufalino, C.4    Messer, K.5    Mestas, J.6
  • 9
    • 84928736645 scopus 로고    scopus 로고
    • Mechanisms of alveolar epithelial injury, repair, and fibrosis
    • PubMed Abstract | CrossRef Full Text | Google Scholar
    • Chambers RC, Mercer PF. Mechanisms of alveolar epithelial injury, repair, and fibrosis. Ann Am Thorac Soc. (2015) 12(Suppl 1.):S16–20. doi: 10.1513/AnnalsATS.201410-448MG PubMed Abstract | CrossRef Full Text | Google Scholar
    • (2015) Ann Am Thorac Soc , vol.12 , pp. S16-S20
    • Chambers, R.C.1    Mercer, P.F.2
  • 10
    • 0001629045 scopus 로고    scopus 로고
    • Alveolar type I cells
    • Crystal RG, West JB, Weibel ER, Barnes PJ editors. 2nd Edn. Philadelphia, PA: Lippincott-Raven
    • Schneeberger E. Alveolar type I cells. In: Crystal RG, West JB, Weibel ER, Barnes PJ editors. The Lung:Scientific Foundations. 2nd Edn. Philadelphia, PA: Lippincott-Raven (1997). 535–42.
    • (1997) The Lung:Scientific Foundations , pp. 535-542
    • Schneeberger, E.1
  • 11
    • 77952773210 scopus 로고    scopus 로고
    • Epithelial repair mechanisms in the lung
    • PubMed Abstract | CrossRef Full Text | Google Scholar
    • Crosby LM, Waters CM. Epithelial repair mechanisms in the lung. Am J Physiol Lung Cell Mol Physiol. (2010) 298:L715–31. doi: 10.1152/ajplung.00361.2009 PubMed Abstract | CrossRef Full Text | Google Scholar
    • (2010) Am J Physiol Lung Cell Mol Physiol , vol.298 , pp. L715-L731
    • Crosby, L.M.1    Waters, C.M.2
  • 12
    • 84881005368 scopus 로고    scopus 로고
    • Insulin-like growth factor-I stimulates differentiation of ATII cells to ATI-like cells through activation of Wnt5a
    • PubMed Abstract | CrossRef Full Text | Google Scholar
    • Ghosh MC, Gorantla V, Makena PS, Luellen C, Sinclair SE, Schwingshackl A, et al. Insulin-like growth factor-I stimulates differentiation of ATII cells to ATI-like cells through activation of Wnt5a. Am J Physiol Lung Cell Mol Physiol. (2013) 305:L222–8. doi: 10.1152/ajplung.00014.2013 PubMed Abstract | CrossRef Full Text | Google Scholar
    • (2013) Am J Physiol Lung Cell Mol Physiol , vol.305 , pp. L222-L228
    • Ghosh, M.C.1    Gorantla, V.2    Makena, P.S.3    Luellen, C.4    Sinclair, S.E.5    Schwingshackl, A.6
  • 13
    • 0032791063 scopus 로고    scopus 로고
    • Pulmonary surfactant in health and human lung diseases: State of the art
    • PubMed Abstract | CrossRef Full Text | Google Scholar
    • Griese M. Pulmonary surfactant in health and human lung diseases: state of the art. Eur Respir J. (1999) 13:1455–76. doi: 10.1183/09031936.99.13614779 PubMed Abstract | CrossRef Full Text | Google Scholar
    • (1999) Eur Respir J , vol.13 , pp. 1455-1476
    • Griese, M.1
  • 14
    • 0035048532 scopus 로고    scopus 로고
    • Surfactant proteins a and d and pulmonary host defense
    • PubMed Abstract | CrossRef Full Text | Google Scholar
    • Crouch E, Wright JR. Surfactant proteins a and d and pulmonary host defense. Annu Rev Physiol. (2001) 63:521–54. doi: 10.1146/annurev.physiol.63.1.521 PubMed Abstract | CrossRef Full Text | Google Scholar
    • (2001) Annu Rev Physiol , vol.63 , pp. 521-554
    • Crouch, E.1    Wright, J.R.2
  • 15
    • 0034973011 scopus 로고    scopus 로고
    • Surfactant regulation of host defense function in the lung: A question of balance
    • PubMed Abstract | CrossRef Full Text | Google Scholar
    • Phelps DS. Surfactant regulation of host defense function in the lung: a question of balance. Pediatr Pathol Mol Med. (2001) 20:269–92. doi: 10.1080/15513810109168822 PubMed Abstract | CrossRef Full Text | Google Scholar
    • (2001) Pediatr Pathol Mol Med , vol.20 , pp. 269-292
    • Phelps, D.S.1
  • 16
    • 11244287371 scopus 로고    scopus 로고
    • Immunoregulatory functions of surfactant proteins
    • PubMed Abstract | CrossRef Full Text | Google Scholar
    • Wright JR. Immunoregulatory functions of surfactant proteins. Nat Rev Immunol. (2005) 5:58–68. doi: 10.1038/nri1528 PubMed Abstract | CrossRef Full Text | Google Scholar
    • (2005) Nat Rev Immunol , vol.5 , pp. 58-68
    • Wright, J.R.1
  • 17
    • 65949105477 scopus 로고    scopus 로고
    • Genetic complexity of the human innate host defense molecules, surfactant protein A1 (SP-A1) and SP-A2–impact on function
    • PubMed Abstract | CrossRef Full Text |
    • Floros J, Wang G, Mikerov AN. Genetic complexity of the human innate host defense molecules, surfactant protein A1 (SP-A1) and SP-A2–impact on function. Crit Rev Eukaryot Gene Exp. (2009) 19:125–37. doi: 10.1615/CritRevEukarGeneExpr.v19.i2.30 PubMed Abstract | CrossRef Full Text |
    • (2009) Crit Rev Eukaryot Gene Exp , vol.19 , pp. 125-137
    • Floros, J.1    Wang, G.2    Mikerov, A.N.3
  • 18
    • 0031132583 scopus 로고    scopus 로고
    • Surfactant protein A-deficient mice are susceptible to group B streptococcal infection
    • PubMed Abstract | Google Scholar
    • LeVine AM, Bruno MD, Huelsman KM, Ross GF, Whitsett JA, Korfhagen TR. Surfactant protein A-deficient mice are susceptible to group B streptococcal infection. J Immunol. (1997) 158:4336–40. PubMed Abstract | Google Scholar
    • (1997) J Immunol , vol.158 , pp. 4336-4340
    • LeVine, A.M.1    Bruno, M.D.2    Huelsman, K.M.3    Ross, G.F.4    Whitsett, J.A.5    Korfhagen, T.R.6
  • 19
    • 0032185233 scopus 로고    scopus 로고
    • Surfactant protein-A-deficient mice are susceptible to Pseudomonas aeruginosa infection
    • PubMed Abstract | CrossRef Full Text | Google Scholar
    • LeVine AM, Kurak KE, Bruno MD, Stark JM, Whitsett JA, Korfhagen TR. Surfactant protein-A-deficient mice are susceptible to Pseudomonas aeruginosa infection. Am J Respir Cell Mol Biol. (1998) 19:700–8. doi: 10.1165/ajrcmb.19.4.3254 PubMed Abstract | CrossRef Full Text | Google Scholar
    • (1998) Am J Respir Cell Mol Biol , vol.19 , pp. 700-708
    • LeVine, A.M.1    Kurak, K.E.2    Bruno, M.D.3    Stark, J.M.4    Whitsett, J.A.5    Korfhagen, T.R.6
  • 20
    • 0034292361 scopus 로고    scopus 로고
    • Distinct effects of surfactant protein A or D deficiency during bacterial infection on the lung
    • PubMed Abstract | CrossRef Full Text | Google Scholar
    • LeVine AM, Whitsett JA, Gwozdz JA, Richardson TR, Fisher JH, Burhans MS, et al. Distinct effects of surfactant protein A or D deficiency during bacterial infection on the lung. J Immunol. (2000) 165:3934–40. doi: 10.4049/jimmunol.165.7.3934 PubMed Abstract | CrossRef Full Text | Google Scholar
    • (2000) J Immunol , vol.165 , pp. 3934-3940
    • LeVine, A.M.1    Whitsett, J.A.2    Gwozdz, J.A.3    Richardson, T.R.4    Fisher, J.H.5    Burhans, M.S.6
  • 21
    • 63349095713 scopus 로고    scopus 로고
    • Ablation of SPA has a negative impact on the susceptibility of mice to Klebsiella pneumoniae infection after ozone exposure: Sex differences
    • PubMed Abstract | CrossRef Full Text | Google Scholar
    • Mikerov AN, Haque R, Gan X, Guo X, Phelps DS, Floros J. Ablation of SPA has a negative impact on the susceptibility of mice to Klebsiella pneumoniae infection after ozone exposure: sex differences. Respir Res. (2008) 9:77. doi: 10.1186/1465-9921-9-77 PubMed Abstract | CrossRef Full Text | Google Scholar
    • (2008) Respir Res , vol.9 , pp. 77
    • Mikerov, A.N.1    Haque, R.2    Gan, X.3    Guo, X.4    Phelps, D.S.5    Floros, J.6
  • 22
    • 84862799086 scopus 로고    scopus 로고
    • Impact of sex and ozone exposure on the course of pneumonia in wild type and SP-A (-/-) mice
    • PubMed Abstract | CrossRef Full Text | Google Scholar
    • Mikerov AN, Hu S, Durrani F, Gan X, Wang G, Umstead TM, et al. Impact of sex and ozone exposure on the course of pneumonia in wild type and SP-A (-/-) mice. Microb Pathog. (2012) 52:239–49. doi: 10.1016/j.micpath.2012.01.005 PubMed Abstract | CrossRef Full Text | Google Scholar
    • (2012) Microb Pathog , vol.52 , pp. 239-249
    • Mikerov, A.N.1    Hu, S.2    Durrani, F.3    Gan, X.4    Wang, G.5    Umstead, T.M.6
  • 23
    • 41649086980 scopus 로고    scopus 로고
    • Sex differences in the impact of ozone on survival and alveolar macrophage function of mice after Klebsiella pneumoniae infection
    • PubMed Abstract | CrossRef Full Text | Google Scholar
    • Mikerov AN, Gan X, Umstead TM, Miller L, Chinchilli VM, Phelps DS, et al. Sex differences in the impact of ozone on survival and alveolar macrophage function of mice after Klebsiella pneumoniae infection. Respir Res. (2008) 9:24. doi: 10.1186/1465-9921-9-24 PubMed Abstract | CrossRef Full Text | Google Scholar
    • (2008) Respir Res , vol.9 , pp. 24
    • Mikerov, A.N.1    Gan, X.2    Umstead, T.M.3    Miller, L.4    Chinchilli, V.M.5    Phelps, D.S.6
  • 24
    • 80055000222 scopus 로고    scopus 로고
    • In vivo rescue of alveolar macrophages from SP-A knockout mice with exogenous SP-A nearly restores a wild type intracellular proteome; actin involvement
    • PubMed Abstract | CrossRef Full Text | Google Scholar
    • Phelps DS, Umstead TM, Quintero OA, Yengo CM, Floros J. In vivo rescue of alveolar macrophages from SP-A knockout mice with exogenous SP-A nearly restores a wild type intracellular proteome; actin involvement. Proteome Sci. (2011) 9:67. doi: 10.1186/1477-5956-9-67 PubMed Abstract | CrossRef Full Text | Google Scholar
    • (2011) Proteome Sci , vol.9 , pp. 67
    • Phelps, D.S.1    Umstead, T.M.2    Quintero, O.A.3    Yengo, C.M.4    Floros, J.5
  • 25
    • 84873657306 scopus 로고    scopus 로고
    • Sex differences in the response of the alveolar macrophage proteome to treatment with exogenous surfactant protein-A
    • PubMed Abstract | CrossRef Full Text | Google Scholar
    • Phelps DS, Umstead TM, Floros J. Sex differences in the response of the alveolar macrophage proteome to treatment with exogenous surfactant protein-A. Proteome Sci. (2012) 10:44. doi: 10.1186/1477-5956-10-44 PubMed Abstract | CrossRef Full Text | Google Scholar
    • (2012) Proteome Sci , vol.10 , pp. 44
    • Phelps, D.S.1    Umstead, T.M.2    Floros, J.3
  • 26
    • 84962721703 scopus 로고    scopus 로고
    • Single-cell analysis reveals differential regulation of the alveolar macrophage actin cytoskeleton by surfactant proteins A1 and A2: Implications of sex and aging
    • PubMed Abstract | CrossRef Full Text | Google Scholar
    • Tsotakos N, Phelps DS, Yengo CM, Chinchilli VM, Floros J. Single-cell analysis reveals differential regulation of the alveolar macrophage actin cytoskeleton by surfactant proteins A1 and A2: implications of sex and aging. Biol Sex Differ. (2016) 7:18. doi: 10.1186/s13293-016-0071-0 PubMed Abstract | CrossRef Full Text | Google Scholar
    • (2016) Biol Sex Differ , vol.7 , pp. 18
    • Tsotakos, N.1    Phelps, D.S.2    Yengo, C.M.3    Chinchilli, V.M.4    Floros, J.5
  • 28
    • 1242284501 scopus 로고    scopus 로고
    • Human SP-A genetic variants and bleomycin-induced cytokine production by THP-1 cells: Effect of ozone-induced SP-A oxidation
    • PubMed Abstract | CrossRef Full Text | Google Scholar
    • Huang W, Wang G, Phelps DS, Al-Mondhiry H, Floros J. Human SP-A genetic variants and bleomycin-induced cytokine production by THP-1 cells: effect of ozone-induced SP-A oxidation. Am J Physiol Lung Cell Mol Physiol. (2004) 286:L546–53. doi: 10.1152/ajplung.00267.2003 PubMed Abstract | CrossRef Full Text | Google Scholar
    • (2004) Am J Physiol Lung Cell Mol Physiol , vol.286 , pp. L546-L553
    • Huang, W.1    Wang, G.2    Phelps, D.S.3    Al-Mondhiry, H.4    Floros, J.5
  • 29
    • 12144282041 scopus 로고    scopus 로고
    • Modulatory effects of ozone on THP-1 cells in response to SP-A stimulation
    • PubMed Abstract | CrossRef Full Text | Google Scholar
    • Janic B, Umstead TM, Phelps DS, Floros J. Modulatory effects of ozone on THP-1 cells in response to SP-A stimulation. Am J Physiol Lung Cell Mol Physiol. (2005) 288:L317–25. doi: 10.1152/ajplung.00125.2004 PubMed Abstract | CrossRef Full Text | Google Scholar
    • (2005) Am J Physiol Lung Cell Mol Physiol , vol.288 , pp. L317-L325
    • Janic, B.1    Umstead, T.M.2    Phelps, D.S.3    Floros, J.4
  • 30
    • 34247345343 scopus 로고    scopus 로고
    • Signal transduction pathways of tumor necrosis factor–mediated lung injury induced by ozone in mice
    • PubMed Abstract | CrossRef Full Text | Google Scholar
    • Cho HY, Morgan DL, Bauer AK, Kleeberger SR. Signal transduction pathways of tumor necrosis factor–mediated lung injury induced by ozone in mice. Am J Respir Crit Care Med. (2007) 175:829–39. doi: 10.1164/rccm.200509-1527OC PubMed Abstract | CrossRef Full Text | Google Scholar
    • (2007) Am J Respir Crit Care Med , vol.175 , pp. 829-839
    • Cho, H.Y.1    Morgan, D.L.2    Bauer, A.K.3    Kleeberger, S.R.4
  • 31
    • 40749146844 scopus 로고    scopus 로고
    • Impact of ozone exposure on the phagocytic activity of human surfactant protein A (SP-A) and SP-A variants
    • PubMed Abstract | CrossRef Full Text | Google Scholar
    • Mikerov AN, Umstead TM, Gan X, Huang W, Guo X, Wang G, et al. Impact of ozone exposure on the phagocytic activity of human surfactant protein A (SP-A) and SP-A variants. Am J Physiol Lung Cell Mol Physiol. (2008) 294:L121–30. doi: 10.1152/ajplung.00288.2007 PubMed Abstract | CrossRef Full Text | Google Scholar
    • (2008) Am J Physiol Lung Cell Mol Physiol , vol.294 , pp. L121-L130
    • Mikerov, A.N.1    Umstead, T.M.2    Gan, X.3    Huang, W.4    Guo, X.5    Wang, G.6
  • 32
    • 64749102981 scopus 로고    scopus 로고
    • The impact of surfactant protein-A on ozone-induced changes in the mouse bronchoalveolar lavage proteome
    • PubMed Abstract | CrossRef Full Text | Google Scholar
    • Haque R, Umstead TM, Freeman WM, Floros J, Phelps DS. The impact of surfactant protein-A on ozone-induced changes in the mouse bronchoalveolar lavage proteome. Proteome Sci. (2009) 7:12. doi: 10.1186/1477-5956-7-12 PubMed Abstract | CrossRef Full Text | Google Scholar
    • (2009) Proteome Sci , vol.7 , pp. 12
    • Haque, R.1    Umstead, T.M.2    Freeman, W.M.3    Floros, J.4    Phelps, D.S.5
  • 33
    • 84857293874 scopus 로고    scopus 로고
    • Ozone-induced lung injury and sterile inflammation. Role of toll-like receptor 4
    • PubMed Abstract | CrossRef Full Text | Google Scholar
    • Connor AJ, Laskin JD, Laskin DL. Ozone-induced lung injury and sterile inflammation. Role of toll-like receptor 4. Exp Mol Pathol. (2012) 92:229–35. doi: 10.1016/j.yexmp.2012.01.004 PubMed Abstract | CrossRef Full Text | Google Scholar
    • (2012) Exp Mol Pathol , vol.92 , pp. 229-235
    • Connor, A.J.1    Laskin, J.D.2    Laskin, D.L.3
  • 34
    • 84903574697 scopus 로고    scopus 로고
    • Differences in the alveolar macrophage proteome in transgenic mice expressing human SP-A1 and SP-A2
    • PubMed Abstract | CrossRef Full Text | Google Scholar
    • Phelps DS, Umstead TM, Silveyra P, Hu S, Wang G, Floros J. Differences in the alveolar macrophage proteome in transgenic mice expressing human SP-A1 and SP-A2. J Proteom Genom Res. (2013) 1:2–26. doi: 10.14302/issn.2326-0793.jpgr-12-207 PubMed Abstract | CrossRef Full Text | Google Scholar
    • (2013) J Proteom Genom Res , vol.1 , pp. 2-26
    • Phelps, D.S.1    Umstead, T.M.2    Silveyra, P.3    Hu, S.4    Wang, G.5    Floros, J.6
  • 35
    • 84903555163 scopus 로고    scopus 로고
    • Sex differences in the acute in vivo effects of different human SP-A variants on the mouse alveolar macrophage proteome
    • PubMed Abstract | CrossRef Full Text | Google Scholar
    • Phelps DS, Umstead TM, Floros J. Sex differences in the acute in vivo effects of different human SP-A variants on the mouse alveolar macrophage proteome. J Proteomics. (2014) 108:427–44. doi: 10.1016/j.jprot.2014.06.007 PubMed Abstract | CrossRef Full Text | Google Scholar
    • (2014) J Proteomics , vol.108 , pp. 427-444
    • Phelps, D.S.1    Umstead, T.M.2    Floros, J.3
  • 36
    • 0036151311 scopus 로고    scopus 로고
    • The effect of ozone exposure on the ability of human surfactant protein a variants to stimulate cytokine production
    • PubMed Abstract | CrossRef Full Text | Google Scholar
    • Wang G, Umstead T, Phelps D, Al-Mondhiry H, Floros J. The effect of ozone exposure on the ability of human surfactant protein a variants to stimulate cytokine production. Environ Health Perspect. (2002) 110:79–84. doi: 10.1289/ehp.0211079 PubMed Abstract | CrossRef Full Text | Google Scholar
    • (2002) Environ Health Perspect , vol.110 , pp. 79-84
    • Wang, G.1    Umstead, T.2    Phelps, D.3    Al-Mondhiry, H.4    Floros, J.5
  • 37
    • 11144298936 scopus 로고    scopus 로고
    • SP-A1 and SP-A2 variants differentially enhance association of Pseudomonas aeruginosa with rat alveolar macrophages
    • PubMed Abstract | CrossRef Full Text | Google Scholar
    • Mikerov AN, Umstead TM, Huang W, Liu W, Phelps DS, Floros J. SP-A1 and SP-A2 variants differentially enhance association of Pseudomonas aeruginosa with rat alveolar macrophages. Am J Physiol Lung Cell Mol Physiol. (2005) 288:L150–8. doi: 10.1152/ajplung.00135.2004 PubMed Abstract | CrossRef Full Text | Google Scholar
    • (2005) Am J Physiol Lung Cell Mol Physiol , vol.288 , pp. L150-L158
    • Mikerov, A.N.1    Umstead, T.M.2    Huang, W.3    Liu, W.4    Phelps, D.S.5    Floros, J.6
  • 38
    • 33847751163 scopus 로고    scopus 로고
    • Surfactant protein A2 (SP-A2) variants expressed in CHO cells stimulate phagocytosis of Pseudomonas aeruginosa more than do SP-A1 variants
    • PubMed Abstract | CrossRef Full Text | Google Scholar
    • Mikerov A, Wang G, Umstead T, Zacharatos M, Thomas N, Phelps D, et al. Surfactant protein A2 (SP-A2) variants expressed in CHO cells stimulate phagocytosis of Pseudomonas aeruginosa more than do SP-A1 variants. Infect Immun. (2007) 75:1403–12. doi: 10.1128/IAI.01341-06 PubMed Abstract | CrossRef Full Text | Google Scholar
    • (2007) Infect Immun , vol.75 , pp. 1403-1412
    • Mikerov, A.1    Wang, G.2    Umstead, T.3    Zacharatos, M.4    Thomas, N.5    Phelps, D.6
  • 39
    • 1842583880 scopus 로고    scopus 로고
    • Differences in biochemical properties and in biological function between human SP-A1 and SP-A2 variants, and the impact of ozone-induced oxidation
    • PubMed Abstract | CrossRef Full Text | Google Scholar
    • Wang G, Bates-Kenney SR, Tao JQ, Phelps DS, Floros J. Differences in biochemical properties and in biological function between human SP-A1 and SP-A2 variants, and the impact of ozone-induced oxidation. Biochemistry. (2004) 43:4227–39. doi: 10.1021/bi036023i PubMed Abstract | CrossRef Full Text | Google Scholar
    • (2004) Biochemistry , vol.43 , pp. 4227-4239
    • Wang, G.1    Bates-Kenney, S.R.2    Tao, J.Q.3    Phelps, D.S.4    Floros, J.5
  • 40
    • 34548598714 scopus 로고    scopus 로고
    • Differential effects of human SP-A1 and SP-A2 variants on phospholipid monolayers containing surfactant protein B
    • PubMed Abstract | CrossRef Full Text | Google Scholar
    • Wang G, Taneva S, Keough KM, Floros J. Differential effects of human SP-A1 and SP-A2 variants on phospholipid monolayers containing surfactant protein B. Biochim Biophys Acta. (2007) 1768:2060–9. doi: 10.1016/j.bbamem.2007.06.025 PubMed Abstract | CrossRef Full Text | Google Scholar
    • (2007) Biochim Biophys Acta , vol.1768 , pp. 2060-2069
    • Wang, G.1    Taneva, S.2    Keough, K.M.3    Floros, J.4
  • 41
    • 84981172738 scopus 로고    scopus 로고
    • Human pulmonary surfactant protein SP-A1 provides maximal efficiency of lung interfacial films
    • PubMed Abstract | CrossRef Full Text | Google Scholar
    • Lopez-Rodriguez E, Pascual A, Arroyo R, Floros J, Perez-Gil J. Human pulmonary surfactant protein SP-A1 provides maximal efficiency of lung interfacial films. Biophys J. (2016) 111:524–36. doi: 10.1016/j.bpj.2016.06.025 PubMed Abstract | CrossRef Full Text | Google Scholar
    • (2016) Biophys J , vol.111 , pp. 524-536
    • Lopez-Rodriguez, E.1    Pascual, A.2    Arroyo, R.3    Floros, J.4    Perez-Gil, J.5
  • 42
    • 85037111818 scopus 로고    scopus 로고
    • SP-A2 contributes to miRNA-mediated sex differences in response to oxidative stress: Pro-inflammatory, anti-apoptotic, and anti-oxidant pathways are involved
    • PubMed Abstract | CrossRef Full Text | Google Scholar
    • Noutsios GT, Thorenoor N, Zhang X, Phelps DS, Umstead TM, Durrani F, et al. SP-A2 contributes to miRNA-mediated sex differences in response to oxidative stress: pro-inflammatory, anti-apoptotic, and anti-oxidant pathways are involved. Biol Sex Differ. (2017) 8:37. doi: 10.1186/s13293-017-0158-2 PubMed Abstract | CrossRef Full Text | Google Scholar
    • (2017) Biol Sex Differ , vol.8 , pp. 37
    • Noutsios, G.T.1    Thorenoor, N.2    Zhang, X.3    Phelps, D.S.4    Umstead, T.M.5    Durrani, F.6
  • 43
    • 85041486516 scopus 로고    scopus 로고
    • Differential effects of innate immune variants of surfactant protein-A1 (SFTPA1) and SP-A2 (SFTPA2) in airway function after Klebsiella pneumoniae infection and sex differences
    • PubMed Abstract | CrossRef Full Text | Google Scholar
    • Thorenoor N, Zhang X, Umstead TM, Scott Halstead E, Phelps DS, Floros J. Differential effects of innate immune variants of surfactant protein-A1 (SFTPA1) and SP-A2 (SFTPA2) in airway function after Klebsiella pneumoniae infection and sex differences. Respir Res. (2018) 19:23. doi: 10.1186/s12931-018-0723-1 PubMed Abstract | CrossRef Full Text | Google Scholar
    • (2018) Respir Res , vol.19 , pp. 23
    • Thorenoor, N.1    Zhang, X.2    Umstead, T.M.3    Scott Halstead, E.4    Phelps, D.S.5    Floros, J.6
  • 44
    • 85055287431 scopus 로고    scopus 로고
    • Survival of surfactant protein-A1 and SP-A2 transgenic mice after Klebsiella pneumoniae infection, exhibits sex-, gene-, and variant specific differences; treatment with surfactant protein improves survival
    • PubMed Abstract | CrossRef Full Text | Google Scholar
    • Thorenoor N, Umstead T, Zhang X, Phelps D, Floros J. Survival of surfactant protein-A1 and SP-A2 transgenic mice after Klebsiella pneumoniae infection, exhibits sex-, gene-, and variant specific differences; treatment with surfactant protein improves survival. Front Immunol. (2018) 9:2404. doi: 10.3389/fimmu.2018.02404 PubMed Abstract | CrossRef Full Text | Google Scholar
    • (2018) Front Immunol , vol.9 , pp. 2404
    • Thorenoor, N.1    Umstead, T.2    Zhang, X.3    Phelps, D.4    Floros, J.5
  • 45
    • 77957336599 scopus 로고    scopus 로고
    • Human SP-A1 (SFTPA1) variant-specific 3' UTRs and poly(A) tail differentially affect the in vitro translation of a reporter gene
    • PubMed Abstract | CrossRef Full Text | Google Scholar
    • Silveyra P, Wang G, Floros J. Human SP-A1 (SFTPA1) variant-specific 3' UTRs and poly(A) tail differentially affect the in vitro translation of a reporter gene. Am J Physiol Lung Cell Mol Physiol. (2010) 299:L523–34. doi: 10.1152/ajplung.00113.2010 PubMed Abstract | CrossRef Full Text | Google Scholar
    • (2010) Am J Physiol Lung Cell Mol Physiol , vol.299 , pp. L523-L534
    • Silveyra, P.1    Wang, G.2    Floros, J.3
  • 46
    • 84906046244 scopus 로고    scopus 로고
    • Knockdown of Drosha in human alveolar type II cells alters expression of SP-A in culture: A pilot study
    • PubMed Abstract | CrossRef Full Text | Google Scholar
    • Silveyra P, Chroneos ZC, DiAngelo SL, Thomas NJ, Noutsios GT, Tsotakos N, et al. Knockdown of Drosha in human alveolar type II cells alters expression of SP-A in culture: a pilot study. Exp Lung Res. (2014) 40:354–66. doi: 10.3109/01902148.2014.929757 PubMed Abstract | CrossRef Full Text | Google Scholar
    • (2014) Exp Lung Res , vol.40 , pp. 354-366
    • Silveyra, P.1    Chroneos, Z.C.2    DiAngelo, S.L.3    Thomas, N.J.4    Noutsios, G.T.5    Tsotakos, N.6
  • 47
    • 77951251157 scopus 로고    scopus 로고
    • Humanized SFTPA1 and SFTPA2 transgenic mice reveal functional divergence of SP-A1 and SP-A2: Formation of tubular myelin in vivo requires both gene products
    • PubMed Abstract | CrossRef Full Text | Google Scholar
    • Wang G, Guo X, Diangelo S, Thomas NJ, Floros J. Humanized SFTPA1 and SFTPA2 transgenic mice reveal functional divergence of SP-A1 and SP-A2: formation of tubular myelin in vivo requires both gene products. J Biol Chem. (2010) 285:11998–2010. doi: 10.1074/jbc.M109.046243 PubMed Abstract | CrossRef Full Text | Google Scholar
    • (2010) J Biol Chem , vol.285 , pp. 11998-12010
    • Wang, G.1    Guo, X.2    Diangelo, S.3    Thomas, N.J.4    Floros, J.5
  • 48
    • 33947239491 scopus 로고    scopus 로고
    • Role of surfactant protein-A (SP-A) in lung injury in response to acute ozone exposure of SP-A deficient mice
    • PubMed Abstract | CrossRef Full Text | Google Scholar
    • Haque R, Umstead TM, Ponnuru P, Guo X, Hawgood S, Phelps DS, et al. Role of surfactant protein-A (SP-A) in lung injury in response to acute ozone exposure of SP-A deficient mice. Toxicol Appl Pharmacol. (2007) 220:72–82. doi: 10.1016/j.taap.2006.12.017 PubMed Abstract | CrossRef Full Text | Google Scholar
    • (2007) Toxicol Appl Pharmacol , vol.220 , pp. 72-82
    • Haque, R.1    Umstead, T.M.2    Ponnuru, P.3    Guo, X.4    Hawgood, S.5    Phelps, D.S.6
  • 49
    • 0036013093 scopus 로고    scopus 로고
    • In vitro exposure of proteins to ozone
    • PubMed Abstract | CrossRef Full Text | Google Scholar
    • Umstead TM, Phelps DS, Wang G, Floros J, Tarkington BK. In vitro exposure of proteins to ozone. Toxicol Mech Methods. (2002) 12:1–16. doi: 10.1080/1537-650291895739 PubMed Abstract | CrossRef Full Text | Google Scholar
    • (2002) Toxicol Mech Methods , vol.12 , pp. 1-16
    • Umstead, T.M.1    Phelps, D.S.2    Wang, G.3    Floros, J.4    Tarkington, B.K.5
  • 50
    • 84872683119 scopus 로고    scopus 로고
    • Efficient and rapid isolation and purification of mouse alveolar type II epithelial cells
    • PubMed Abstract | CrossRef Full Text | Google Scholar
    • Messier EM, Mason RJ, Kosmider B. Efficient and rapid isolation and purification of mouse alveolar type II epithelial cells. Exp Lung Res. (2012) 38:363–73. doi: 10.3109/01902148.2012.713077 PubMed Abstract | CrossRef Full Text | Google Scholar
    • (2012) Exp Lung Res , vol.38 , pp. 363-373
    • Messier, E.M.1    Mason, R.J.2    Kosmider, B.3
  • 51
    • 84857993106 scopus 로고    scopus 로고
    • Gonadal hormones and oxidative stress interaction differentially affects survival of Male and female mice after lung Klebsiella pneumoniae infection
    • PubMed Abstract | CrossRef Full Text | Google Scholar
    • Durrani F, Phelps DS, Weisz J, Silveyra P, Hu S, Mikerov AN, et al. Gonadal hormones and oxidative stress interaction differentially affects survival of male and female mice after lung Klebsiella pneumoniae infection. Exp Lung Res. (2012) 38:165–72. doi: 10.3109/01902148.2011.654045 PubMed Abstract | CrossRef Full Text | Google Scholar
    • (2012) Exp Lung Res , vol.38 , pp. 165-172
    • Durrani, F.1    Phelps, D.S.2    Weisz, J.3    Silveyra, P.4    Hu, S.5    Mikerov, A.N.6
  • 52
    • 84880002392 scopus 로고    scopus 로고
    • TCC: An R package for comparing tag count data with robust normalization strategies
    • PubMed Abstract | CrossRef Full Text | Google Scholar
    • Sun J, Nishiyama T, Shimizu K, Kadota K. TCC: an R package for comparing tag count data with robust normalization strategies. BMC Bioinformatics. (2013) 14:219. doi: 10.1186/1471-2105-14-219 PubMed Abstract | CrossRef Full Text | Google Scholar
    • (2013) BMC Bioinformatics , vol.14 , pp. 219
    • Sun, J.1    Nishiyama, T.2    Shimizu, K.3    Kadota, K.4
  • 53
    • 84946224850 scopus 로고    scopus 로고
    • MiRNA nomenclature: A view incorporating genetic origins, biosynthetic pathways, and sequence variants
    • PubMed Abstract | CrossRef Full Text | Google Scholar
    • Desvignes T, Batzel P, Berezikov E, Eilbeck K, Eppig JT, McAndrews MS, et al. miRNA nomenclature: a view incorporating genetic origins, biosynthetic pathways, and sequence variants. Trends Genet. (2015) 31:613–26. doi: 10.1016/j.tig.2015.09.002 PubMed Abstract | CrossRef Full Text | Google Scholar
    • (2015) Trends Genet , vol.31 , pp. 613-626
    • Desvignes, T.1    Batzel, P.2    Berezikov, E.3    Eilbeck, K.4    Eppig, J.T.5    McAndrews, M.S.6
  • 54
    • 85017316436 scopus 로고    scopus 로고
    • Minimal standards for reporting microRNA:target interactions
    • PubMed Abstract | CrossRef Full Text | Google Scholar
    • Piletič K, Kunej T. Minimal standards for reporting microRNA:target interactions. OMICS. (2017) 21:197–206. doi: 10.1089/omi.2017.0023 PubMed Abstract | CrossRef Full Text | Google Scholar
    • (2017) OMICS , vol.21 , pp. 197-206
    • Piletič, K.1    Kunej, T.2
  • 55
    • 0042427478 scopus 로고    scopus 로고
    • Oxidative stress stimulates multiple MAPK signalling pathways and phosphorylation of the small HSP27 in the perfused amphibian heart
    • PubMed Abstract | CrossRef Full Text | Google Scholar
    • Gaitanaki C, Konstantina S, Chrysa S, Beis I. Oxidative stress stimulates multiple MAPK signalling pathways and phosphorylation of the small HSP27 in the perfused amphibian heart. J Exp Biol. (2003) 206(Pt 16):2759–69. doi: 10.1242/jeb.00483 PubMed Abstract | CrossRef Full Text | Google Scholar
    • (2003) J Exp Biol , vol.206 , pp. 2759-2769
    • Gaitanaki, C.1    Konstantina, S.2    Chrysa, S.3    Beis, I.4
  • 56
    • 30544454184 scopus 로고    scopus 로고
    • Role of oxidative stress in ERK and p38 MAPK activation induced by the chemical sensitizer DNFB in a fetal skin dendritic cell line
    • PubMed Abstract | CrossRef Full Text | Google Scholar
    • Matos TJ, Duarte CB, Gonçalo M, Lopes MC. Role of oxidative stress in ERK and p38 MAPK activation induced by the chemical sensitizer DNFB in a fetal skin dendritic cell line. Immunol Cell Biol. (2005) 83:607–14. doi: 10.1111/j.1440-1711.2005.01378.x PubMed Abstract | CrossRef Full Text | Google Scholar
    • (2005) Immunol Cell Biol , vol.83 , pp. 607-614
    • Matos, T.J.1    Duarte, C.B.2    Gonçalo, M.3    Lopes, M.C.4
  • 57
    • 80054993459 scopus 로고    scopus 로고
    • Mitogen-activated protein kinases and reactive oxygen species: How can ROS activate MAPK pathways?
    • PubMed Abstract | CrossRef Full Text | Google Scholar
    • Son Y, Cheong YK, Kim NH, Chung HT, Kang DG, Pae HO. Mitogen-activated protein kinases and reactive oxygen species: how can ROS activate MAPK pathways? J Signal Transduct. (2011) 2011:792639. doi: 10.1155/2011/792639 PubMed Abstract | CrossRef Full Text | Google Scholar
    • (2011) J Signal Transduct , vol.2011 , pp. 792639
    • Son, Y.1    Cheong, Y.K.2    Kim, N.H.3    Chung, H.T.4    Kang, D.G.5    Pae, H.O.6
  • 58
    • 84924860402 scopus 로고    scopus 로고
    • MicroRNAs in renal cell carcinoma: A systematic review of clinical implications (Review)
    • PubMed Abstract | CrossRef Full Text | Google Scholar
    • Li M, Wang Y, Song Y, Bu R, Yin B, Fei X, et al. MicroRNAs in renal cell carcinoma: a systematic review of clinical implications (Review). Oncol Rep. (2015) 33:1571–8. doi: 10.3892/or.2015.3799 PubMed Abstract | CrossRef Full Text | Google Scholar
    • (2015) Oncol Rep , vol.33 , pp. 1571-1578
    • Li, M.1    Wang, Y.2    Song, Y.3    Bu, R.4    Yin, B.5    Fei, X.6
  • 59
    • 33745537991 scopus 로고    scopus 로고
    • The von Hippel-Lindau tumour-suppressor protein interaction with protein kinase Cdelta
    • PubMed Abstract | CrossRef Full Text | Google Scholar
    • Iturrioz X, Durgan J, Calleja V, Larijani B, Okuda H, Whelan R, et al. The von Hippel-Lindau tumour-suppressor protein interaction with protein kinase Cdelta. Biochem J. (2006) 397:109–20. doi: 10.1042/BJ20060354 PubMed Abstract | CrossRef Full Text | Google Scholar
    • (2006) Biochem J , vol.397 , pp. 109-120
    • Iturrioz, X.1    Durgan, J.2    Calleja, V.3    Larijani, B.4    Okuda, H.5    Whelan, R.6
  • 60
    • 0033776182 scopus 로고    scopus 로고
    • VHL takes HIF's breath away
    • PubMed Abstract | CrossRef Full Text | Google Scholar
    • Krek W. VHL takes HIF's breath away. Nat Cell Biol. (2000) 2:E121–3. doi: 10.1038/35017129 PubMed Abstract | CrossRef Full Text | Google Scholar
    • (2000) Nat Cell Biol , vol.2 , pp. E121-E123
    • Krek, W.1
  • 61
    • 85011831946 scopus 로고    scopus 로고
    • MiR-141 promotes colon cancer cell proliferation by inhibiting MAP2K4
    • PubMed Abstract | CrossRef Full Text | Google Scholar
    • Ding L, Yu LL, Han N, Zhang BT. miR-141 promotes colon cancer cell proliferation by inhibiting MAP2K4. Oncol Lett. (2017) 13:1665–71. doi: 10.3892/ol.2017.5653 PubMed Abstract | CrossRef Full Text | Google Scholar
    • (2017) Oncol Lett , vol.13 , pp. 1665-1671
    • Ding, L.1    Yu, L.L.2    Han, N.3    Zhang, B.T.4
  • 62
    • 70449500709 scopus 로고    scopus 로고
    • Regulation of JAK2 by miR-135a: Prognostic impact in classic Hodgkin lymphoma
    • PubMed Abstract | CrossRef Full Text | Google Scholar
    • Navarro A, Diaz T, Martinez A, Gaya A, Pons A, Gel B, et al. Regulation of JAK2 by miR-135a: prognostic impact in classic Hodgkin lymphoma. Blood. (2009) 114:2945–51. doi: 10.1182/blood-2009-02-204842 PubMed Abstract | CrossRef Full Text | Google Scholar
    • (2009) Blood , vol.114 , pp. 2945-2951
    • Navarro, A.1    Diaz, T.2    Martinez, A.3    Gaya, A.4    Pons, A.5    Gel, B.6
  • 63
    • 84866625196 scopus 로고    scopus 로고
    • Distinct AGO1 and AGO2 associated miRNA profiles in human cells and blood plasma
    • PubMed Abstract | CrossRef Full Text | Google Scholar
    • Turchinovich A, Burwinkel B. Distinct AGO1 and AGO2 associated miRNA profiles in human cells and blood plasma. RNA Biol. (2012) 9:1066–75. doi: 10.4161/rna.21083 PubMed Abstract | CrossRef Full Text | Google Scholar
    • (2012) RNA Biol , vol.9 , pp. 1066-1075
    • Turchinovich, A.1    Burwinkel, B.2
  • 64
    • 78650004201 scopus 로고    scopus 로고
    • MicroRNA: Biogenesis, function and role in cancer
    • PubMed Abstract | CrossRef Full Text | Google Scholar
    • Macfarlane LA, Murphy PR. MicroRNA: Biogenesis, function and role in cancer. Curr Genomics. (2010) 11:537–61. doi: 10.2174/138920210793175895 PubMed Abstract | CrossRef Full Text | Google Scholar
    • (2010) Curr Genomics , vol.11 , pp. 537-561
    • Macfarlane, L.A.1    Murphy, P.R.2
  • 65
    • 84969790458 scopus 로고    scopus 로고
    • Epithelial cell transforming 2 and aurora kinase B modulate formation of stress granule-containing transcripts from diverse cellular pathways in astrocytoma cells
    • PubMed Abstract | CrossRef Full Text | Google Scholar
    • Weeks A, Agnihotri S, Lymer J, Chalil A, Diaz R, Isik S, et al. Epithelial cell transforming 2 and aurora kinase B modulate formation of stress granule-containing transcripts from diverse cellular pathways in astrocytoma cells. Am J Pathol. (2016) 186:1674–87. doi: 10.1016/j.ajpath.2016.02.013 PubMed Abstract | CrossRef Full Text | Google Scholar
    • (2016) Am J Pathol , vol.186 , pp. 1674-1687
    • Weeks, A.1    Agnihotri, S.2    Lymer, J.3    Chalil, A.4    Diaz, R.5    Isik, S.6


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