-
1
-
-
79955617984
-
Mitochondrial dysfunction and oxidative stress in asthma: Implications for mitochondria-targeted antioxidant therapeutics
-
Reddy PH. Mitochondrial dysfunction and oxidative stress in asthma: implications for mitochondria-targeted antioxidant therapeutics. Pharmaceuticals (Basel) 2011;4:429-456.
-
(2011)
Pharmaceuticals (Basel)
, vol.4
, pp. 429-456
-
-
Reddy, P.H.1
-
2
-
-
0035340289
-
Eosinophils are a major source of nitric oxide-derived oxidants in severe asthma: Characterization of pathways available to eosinophils for generating reactive nitrogen species
-
MacPherson JC, Comhair SA, Erzurum SC, Klein DF, Lipscomb MF, Kavuru MS, Samoszuk MK, Hazen SL. Eosinophils are a major source of nitric oxide-derived oxidants in severe asthma: characterization of pathways available to eosinophils for generating reactive nitrogen species. J Immunol 2001;166:5763-5772.
-
(2001)
J Immunol
, vol.166
, pp. 5763-5772
-
-
MacPherson, J.C.1
Comhair, S.A.2
Erzurum, S.C.3
Klein, D.F.4
Lipscomb, M.F.5
Kavuru, M.S.6
Samoszuk, M.K.7
Hazen, S.L.8
-
3
-
-
0034033812
-
Eosinophils generate brominating oxidants in allergen-induced asthma
-
Wu W, Samoszuk MK, Comhair SA, Thomassen MJ, Farver CF, Dweik RA, Kavuru MS, Erzurum SC, Hazen SL. Eosinophils generate brominating oxidants in allergen-induced asthma. J Clin Invest 2000;105:1455-1463.
-
(2000)
J Clin Invest
, vol.105
, pp. 1455-1463
-
-
Wu, W.1
Samoszuk, M.K.2
Comhair, S.A.3
Thomassen, M.J.4
Farver, C.F.5
Dweik, R.A.6
Kavuru, M.S.7
Erzurum, S.C.8
Hazen, S.L.9
-
4
-
-
33644995821
-
Mechanism of nitrite oxidation by eosinophil peroxidase: Implications for oxidant production and nitration by eosinophils
-
van Dalen CJ, Winterbourn CC, Kettle AJ. Mechanism of nitrite oxidation by eosinophil peroxidase: implications for oxidant production and nitration by eosinophils. Biochem J 2006;394: 707-713.
-
(2006)
Biochem J
, vol.394
, pp. 707-713
-
-
Van Dalen, C.J.1
Winterbourn, C.C.2
Kettle, A.J.3
-
5
-
-
79960446443
-
Urinary bromotyrosine measures asthma control and predicts asthma exacerbations in children
-
Wedes SH, Wu W, Comhair SA, McDowell KM, DiDonato JA, Erzurum SC, Hazen SL. Urinary bromotyrosine measures asthma control and predicts asthma exacerbations in children. J Pediatr 2011;159: 248-255.e1.
-
(2011)
J Pediatr
, vol.159
-
-
Wedes, S.H.1
Wu, W.2
Comhair, S.A.3
McDowell, K.M.4
DiDonato, J.A.5
Erzurum, S.C.6
Hazen, S.L.7
-
6
-
-
76149098409
-
Noninvasive markers of airway inflammation in asthma
-
Wedes SH, Khatri SB, Zhang R, Wu W, Comhair SA, Wenzel S, Teague WG, Israel E, Erzurum SC, Hazen SL. Noninvasive markers of airway inflammation in asthma. Clin Transl Sci 2009;2:112-117.
-
(2009)
Clin Transl Sci
, vol.2
, pp. 112-117
-
-
Wedes, S.H.1
Khatri, S.B.2
Zhang, R.3
Wu, W.4
Comhair, S.A.5
Wenzel, S.6
Teague, W.G.7
Israel, E.8
Erzurum, S.C.9
Hazen, S.L.10
-
7
-
-
56149105146
-
Simultaneous detection and quantification of 3-nitrotyrosine and 3-bromotyrosine in human urine by stable isotope dilution liquid chromatography tandem mass spectrometry
-
Chen HJ, Chiu WL. Simultaneous detection and quantification of 3-nitrotyrosine and 3-bromotyrosine in human urine by stable isotope dilution liquid chromatography tandem mass spectrometry. Toxicol Lett 2008;181:31-39.
-
(2008)
Toxicol Lett
, vol.181
, pp. 31-39
-
-
Chen, H.J.1
Chiu, W.L.2
-
8
-
-
3042675247
-
Urinary 3-bromotyrosine and 3-chlorotyrosine concentrations in asthmatic patients: Lack of increase in 3-bromotyrosine concentration in urine and plasma proteins in aspirin-induced asthma after intravenous aspirin challenge
-
Mita H, Higashi N, Taniguchi M, Higashi A, Kawagishi Y, Akiyama K. Urinary 3-bromotyrosine and 3-chlorotyrosine concentrations in asthmatic patients: lack of increase in 3-bromotyrosine concentration in urine and plasma proteins in aspirin-induced asthma after intravenous aspirin challenge. Clin Exp Allergy 2004; 34:931-938.
-
(2004)
Clin Exp Allergy
, vol.34
, pp. 931-938
-
-
Mita, H.1
Higashi, N.2
Taniguchi, M.3
Higashi, A.4
Kawagishi, Y.5
Akiyama, K.6
-
9
-
-
33645961872
-
Nitrotyrosine proteome survey in asthma identifies oxidative mechanism of catalase inactivation
-
Ghosh S, Janocha AJ, Aronica MA, Swaidani S, Comhair SA, Xu W, Zheng L, Kaveti S, Kinter M, Hazen SL, et al. Nitrotyrosine proteome survey in asthma identifies oxidative mechanism of catalase inactivation. J Immunol 2006;176:5587-5597.
-
(2006)
J Immunol
, vol.176
, pp. 5587-5597
-
-
Ghosh, S.1
Janocha, A.J.2
Aronica, M.A.3
Swaidani, S.4
Comhair, S.A.5
Xu, W.6
Zheng, L.7
Kaveti, S.8
Kinter, M.9
Hazen, S.L.10
-
10
-
-
84870154833
-
Relation of oxidant-antioxidant imbalance with disease progression in patients with asthma
-
Ahmad A, Shameem M, Husain Q. Relation of oxidant-antioxidant imbalance with disease progression in patients with asthma. Ann Thorac Med 2012;7:226-232.
-
(2012)
Ann Thorac Med
, vol.7
, pp. 226-232
-
-
Ahmad, A.1
Shameem, M.2
Husain, Q.3
-
12
-
-
0033833221
-
Exhaled 8-isoprostane as an in vivo biomarker of lung oxidative stress in patients with COPD and healthy smokers
-
Montuschi P, Collins JV, Ciabattoni G, Lazzeri N, Corradi M, Kharitonov SA, Barnes PJ. Exhaled 8-isoprostane as an in vivo biomarker of lung oxidative stress in patients with COPD and healthy smokers. Am J Respir Crit Care Med 2000;162:1175-1177.
-
(2000)
Am J Respir Crit Care Med
, vol.162
, pp. 1175-1177
-
-
Montuschi, P.1
Collins, J.V.2
Ciabattoni, G.3
Lazzeri, N.4
Corradi, M.5
Kharitonov, S.A.6
Barnes, P.J.7
-
13
-
-
27644463766
-
Nitrosative stress in the bronchial mucosa of severe chronic obstructive pulmonary disease
-
Ricciardolo FL, Caramori G, Ito K, Capelli A, Brun P, Abatangelo G, Papi A, Chung KF, Adcock I, Barnes PJ, et al. Nitrosative stress in the bronchial mucosa of severe chronic obstructive pulmonary disease. J Allergy Clin Immunol 2005;116:1028-1035.
-
(2005)
J Allergy Clin Immunol
, vol.116
, pp. 1028-1035
-
-
Ricciardolo, F.L.1
Caramori, G.2
Ito, K.3
Capelli, A.4
Brun, P.5
Abatangelo, G.6
Papi, A.7
Chung, K.F.8
Adcock, I.9
Barnes, P.J.10
-
14
-
-
0035500449
-
Quinoid redox cycling as a mechanism for sustained free radical generation by inhaled airborne particulate matter
-
Squadrito GL, Cueto R, Dellinger B, Pryor WA. Quinoid redox cycling as a mechanism for sustained free radical generation by inhaled airborne particulate matter. Free Radic Biol Med 2001;31: 1132-1138.
-
(2001)
Free Radic Biol Med
, vol.31
, pp. 1132-1138
-
-
Squadrito, G.L.1
Cueto, R.2
Dellinger, B.3
Pryor, W.A.4
-
15
-
-
0034763826
-
Role of free radicals in the toxicity of airborne fine particulate matter
-
Dellinger B, Pryor WA, Cueto R, Squadrito GL, Hegde V, Deutsch WA. Role of free radicals in the toxicity of airborne fine particulate matter. Chem Res Toxicol 2001;14:1371-1377.
-
(2001)
Chem Res Toxicol
, vol.14
, pp. 1371-1377
-
-
Dellinger, B.1
Pryor, W.A.2
Cueto, R.3
Squadrito, G.L.4
Hegde, V.5
Deutsch, W.A.6
-
16
-
-
0031398530
-
Prolonged acute exposure to 0.16 ppm ozone induces eosinophilic airway inflammation in asthmatic subjects with allergies
-
Peden DB, Boehlecke B, Horstman D, Devlin R. Prolonged acute exposure to 0.16 ppm ozone induces eosinophilic airway inflammation in asthmatic subjects with allergies. J Allergy Clin Immunol 1997;100:802-808.
-
(1997)
J Allergy Clin Immunol
, vol.100
, pp. 802-808
-
-
Peden, D.B.1
Boehlecke, B.2
Horstman, D.3
Devlin, R.4
-
17
-
-
3142669756
-
Effect of ozone exposure on intracellular glutathione redox state in cultured human airway epithelial cells
-
Todokoro M, Mochizuki H, Tokuyama K, Utsugi M, Dobashi K, Mori M, Morikawa A. Effect of ozone exposure on intracellular glutathione redox state in cultured human airway epithelial cells. Inflammation 2004;28:105-114.
-
(2004)
Inflammation
, vol.28
, pp. 105-114
-
-
Todokoro, M.1
Mochizuki, H.2
Tokuyama, K.3
Utsugi, M.4
Dobashi, K.5
Mori, M.6
Morikawa, A.7
-
18
-
-
0032110291
-
Air pollution particles induce IL-6 gene expression in human airway epithelial cells via NF-kappaB activation
-
Quay JL, Reed W, Samet J, Devlin RB. Air pollution particles induce IL-6 gene expression in human airway epithelial cells via NF-kappaB activation. Am J Respir Cell Mol Biol 1998;19:98-106.
-
(1998)
Am J Respir Cell Mol Biol
, vol.19
, pp. 98-106
-
-
Quay, J.L.1
Reed, W.2
Samet, J.3
Devlin, R.B.4
-
19
-
-
36849073228
-
Respiratory effects of exposure to diesel traffic in persons with asthma
-
McCreanor J, Cullinan P, Nieuwenhuijsen MJ, Stewart-Evans J, Malliarou E, Jarup L, Harrington R, Svartengren M, Han IK, Ohman-Strickland P, et al. Respiratory effects of exposure to diesel traffic in persons with asthma. N Engl J Med 2007;357:2348-2358.
-
(2007)
N Engl J Med
, vol.357
, pp. 2348-2358
-
-
McCreanor, J.1
Cullinan, P.2
Nieuwenhuijsen, M.J.3
Stewart-Evans, J.4
Malliarou, E.5
Jarup, L.6
Harrington, R.7
Svartengren, M.8
Han, I.K.9
Ohman-Strickland, P.10
-
20
-
-
64049108192
-
Acute effects of air pollution on pulmonary function, airway in flammation, and oxidative stress in asthmatic children
-
Liu L, Poon R, Chen L, Frescura AM, Montuschi P, Ciabattoni G, Wheeler A, Dales R. Acute effects of air pollution on pulmonary function, airway in flammation, and oxidative stress in asthmatic children. Environ Health Perspect 2009;117:668-674.
-
(2009)
Environ Health Perspect
, vol.117
, pp. 668-674
-
-
Liu, L.1
Poon, R.2
Chen, L.3
Frescura, A.M.4
Montuschi, P.5
Ciabattoni, G.6
Wheeler, A.7
Dales, R.8
-
21
-
-
46749090083
-
Air pollution, airway inflammation, and lung function in a cohort study of Mexico City schoolchildren
-
Barraza-Villarreal A, Sunyer J, Hernandez-Cadena L, Escamilla-Nuñez MC, Sienra-Monge JJ, Ramírez-Aguilar M, Cortez-Lugo M, Holguin F, Diaz-Sánchez D, Olin AC, et al. Air pollution, airway inflammation, and lung function in a cohort study of Mexico City schoolchildren. Environ Health Perspect 2008;116:832-838.
-
(2008)
Environ Health Perspect
, vol.116
, pp. 832-838
-
-
Barraza-Villarreal, A.1
Sunyer, J.2
Hernandez-Cadena, L.3
Escamilla-Nuñez, M.C.4
Sienra-Monge, J.J.5
Ramírez-Aguilar, M.6
Cortez-Lugo, M.7
Holguin, F.8
Diaz-Sánchez, D.9
Olin, A.C.10
-
22
-
-
77954105455
-
Mitochondrial dysfunction increases allergic airway inflammation
-
Aguilera-Aguirre L, Bacsi A, Saavedra-Molina A, Kurosky A, Sur S, Boldogh I. Mitochondrial dysfunction increases allergic airway inflammation. J Immunol 2009;183:5379-5387.
-
(2009)
J Immunol
, vol.183
, pp. 5379-5387
-
-
Aguilera-Aguirre, L.1
Bacsi, A.2
Saavedra-Molina, A.3
Kurosky, A.4
Sur, S.5
Boldogh, I.6
-
23
-
-
23644456321
-
ROS generated by pollen NADPH oxidase provide a signal that augments antigen-induced allergic airway inflammation
-
Boldogh I, Bacsi A, Choudhury BK, Dharajiya N, Alam R, Hazra TK, Mitra S, Goldblum RM, Sur S. ROS generated by pollen NADPH oxidase provide a signal that augments antigen-induced allergic airway inflammation. J Clin Invest 2005;115:2169-2179.
-
(2005)
J Clin Invest
, vol.115
, pp. 2169-2179
-
-
Boldogh, I.1
Bacsi, A.2
Choudhury, B.K.3
Dharajiya, N.4
Alam, R.5
Hazra, T.K.6
Mitra, S.7
Goldblum, R.M.8
Sur, S.9
-
24
-
-
77951936033
-
Pollen-induced oxidative stress influences both innate and adaptive immune responses via altering dendritic cell functions
-
Csillag A, Boldogh I, Pazmandi K, Magyarics Z, Gogolak P, Sur S, Rajnavolgyi E, Bacsi A. Pollen-induced oxidative stress influences both innate and adaptive immune responses via altering dendritic cell functions. J Immunol 2010;184:2377-2385.
-
(2010)
J Immunol
, vol.184
, pp. 2377-2385
-
-
Csillag, A.1
Boldogh, I.2
Pazmandi, K.3
Magyarics, Z.4
Gogolak, P.5
Sur, S.6
Rajnavolgyi, E.7
Bacsi, A.8
-
25
-
-
14944359140
-
Air pollution and allergy: You are what you breathe
-
Saxon A, Diaz-Sanchez D. Air pollution and allergy: you are what you breathe. Nat Immunol 2005;6:223-226.
-
(2005)
Nat Immunol
, vol.6
, pp. 223-226
-
-
Saxon, A.1
Diaz-Sanchez, D.2
-
26
-
-
73149094075
-
Increased levels of outdoor air pollutants are associated with reduced bronchodilation in children with asthma
-
Hernández-Cadena L, Holguin F, Barraza-Villarreal A, Del Río-Navarro BE, Sienra-Monge JJ, Romieu I. Increased levels of outdoor air pollutants are associated with reduced bronchodilation in children with asthma. Chest 2009;136:1529-1536.
-
(2009)
Chest
, vol.136
, pp. 1529-1536
-
-
Hernández-Cadena, L.1
Holguin, F.2
Barraza-Villarreal, A.3
Del Río-Navarro, B.E.4
Sienra-Monge, J.J.5
Romieu, I.6
-
27
-
-
34547927247
-
Lung function growth in children with long-term exposure to air pollutants in Mexico City
-
Rojas-Martinez R, Perez-Padilla R, Olaiz-Fernandez G, Mendoza- Alvarado L, Moreno-Macias H, Fortoul T, McDonnell W, Loomis D, Romieu I. Lung function growth in children with long-term exposure to air pollutants in Mexico City. Am J Respir Crit Care Med 2007; 176:377-384.
-
(2007)
Am J Respir Crit Care Med
, vol.176
, pp. 377-384
-
-
Rojas-Martinez, R.1
Perez-Padilla, R.2
Olaiz-Fernandez, G.3
Mendoza- Alvarado, L.4
Moreno-Macias, H.5
Fortoul, T.6
McDonnell, W.7
Loomis, D.8
Romieu, I.9
-
28
-
-
0034665985
-
Oxidative mechanisms in tobacco smoke-induced emphysema
-
Seagrave J. Oxidative mechanisms in tobacco smoke-induced emphysema. J Toxicol Environ Health A 2000;61:69-78.
-
(2000)
J Toxicol Environ Health A
, vol.61
, pp. 69-78
-
-
Seagrave, J.1
-
29
-
-
80053543411
-
Dynamic hyperinflation, arterial blood oxygen, and airway oxidative stress in stable patients with COPD
-
García-Rio F, Romero D, Lores V, Casitas R, Hernanz A, Galera R, Alvarez-Sala R, Torres I. Dynamic hyperinflation, arterial blood oxygen, and airway oxidative stress in stable patients with COPD. Chest 2011;140:961-969.
-
(2011)
Chest
, vol.140
, pp. 961-969
-
-
García-Rio, F.1
Romero, D.2
Lores, V.3
Casitas, R.4
Hernanz, A.5
Galera, R.6
Alvarez-Sala, R.7
Torres, I.8
-
30
-
-
16844364420
-
Oxidative stress and airway inflammation in severe exacerbations of COPD
-
Drost EM, Skwarski KM, Sauleda J, Soler N, Roca J, Agusti A, MacNee W. Oxidative stress and airway inflammation in severe exacerbations of COPD. Thorax 2005;60:293-300.
-
(2005)
Thorax
, vol.60
, pp. 293-300
-
-
Drost, E.M.1
Skwarski, K.M.2
Sauleda, J.3
Soler, N.4
Roca, J.5
Agusti, A.6
MacNee, W.7
-
31
-
-
84861234611
-
Systemic inflammatory changes and increased oxidative stress in rural Indian women cooking with biomass fuels
-
Dutta A, Ray MR, Banerjee A. Systemic inflammatory changes and increased oxidative stress in rural Indian women cooking with biomass fuels. Toxicol Appl Pharmacol 2012;261:255-262.
-
(2012)
Toxicol Appl Pharmacol
, vol.261
, pp. 255-262
-
-
Dutta, A.1
Ray, M.R.2
Banerjee, A.3
-
32
-
-
84857122839
-
Activation of protein kinase B (PKB/Akt) and risk of lung cancer among rural women in India who cook with biomass fuel
-
Roychoudhury S, Mondal NK, Mukherjee S, Dutta A, Siddique S, Ray MR. Activation of protein kinase B (PKB/Akt) and risk of lung cancer among rural women in India who cook with biomass fuel. Toxicol Appl Pharmacol 2012;259:45-53.
-
(2012)
Toxicol Appl Pharmacol
, vol.259
, pp. 45-53
-
-
Roychoudhury, S.1
Mondal, N.K.2
Mukherjee, S.3
Dutta, A.4
Siddique, S.5
Ray, M.R.6
-
33
-
-
34249669242
-
Body mass index is associated with reduced exhaled nitric oxide and higher exhaled 8-isoprostanes in asthmatics
-
Komakula S, Khatri S, Mermis J, Savill S, Haque S, Rojas M, Brown L, Teague GW, Holguin F. Body mass index is associated with reduced exhaled nitric oxide and higher exhaled 8-isoprostanes in asthmatics. Respir Res 2007;8:32.
-
(2007)
Respir Res
, vol.8
, pp. 32
-
-
Komakula, S.1
Khatri, S.2
Mermis, J.3
Savill, S.4
Haque, S.5
Rojas, M.6
Brown, L.7
Teague, G.W.8
Holguin, F.9
-
34
-
-
41749115987
-
Airway inflammation in obese and nonobese patients with difficult-to-treat asthma
-
van Veen IH, Ten Brinke A, Sterk PJ, Rabe KF, Bel EH. Airway inflammation in obese and nonobese patients with difficult-to-treat asthma. Allergy 2008;63:570-574.
-
(2008)
Allergy
, vol.63
, pp. 570-574
-
-
Van Veen, I.H.1
Ten Brinke, A.2
Sterk, P.J.3
Rabe, K.F.4
Bel, E.H.5
-
35
-
-
84861008611
-
Cluster analysis of obesity and asthma phenotypes
-
Asthma Clinical Research Network
-
Sutherland ER, Goleva E, King TS, Lehman E, Stevens AD, Jackson LP, Stream AR, Fahy JV, Leung DY; Asthma Clinical Research Network. Cluster analysis of obesity and asthma phenotypes. PLoS ONE 2012;7:e36631.
-
(2012)
PLoS ONE
, vol.7
-
-
Sutherland, E.R.1
Goleva, E.2
King, T.S.3
Lehman, E.4
Stevens, A.D.5
Jackson, L.P.6
Stream, A.R.7
Fahy, J.V.8
Leung, D.Y.9
-
36
-
-
84875697309
-
Obesity impairs apoptotic cell clearance in asthma
-
Fernandez-Boyanapalli R, Goleva E, Kolakowski C, Min E, Day B, Leung DY, Riches DW, Bratton DL, Sutherland ER. Obesity impairs apoptotic cell clearance in asthma. J Allergy Clin Immunol 2013;131: 1041-1047, 1047.e1-3.
-
(2013)
J Allergy Clin Immunol
, vol.131
-
-
Fernandez-Boyanapalli, R.1
Goleva, E.2
Kolakowski, C.3
Min, E.4
Day, B.5
Leung, D.Y.6
Riches, D.W.7
Bratton, D.L.8
Sutherland, E.R.9
-
37
-
-
11344266869
-
Effect of leptin on allergic airway responses in mice
-
Shore SA, Schwartzman IN, Mellema MS, Flynt L, Imrich A, Johnston RA. Effect of leptin on allergic airway responses in mice. J Allergy Clin Immunol 2005;115:103-109.
-
(2005)
J Allergy Clin Immunol
, vol.115
, pp. 103-109
-
-
Shore, S.A.1
Schwartzman, I.N.2
Mellema, M.S.3
Flynt, L.4
Imrich, A.5
Johnston, R.A.6
-
38
-
-
84865824614
-
Alveolar macrophages from overweight/obese subjects with asthma demonstrate a proinflammatory phenotype
-
Lugogo NL, Hollingsworth JW, Howell DL, Que LG, Francisco D, Church TD, Potts-Kant EN, Ingram JL, Wang Y, Jung SH, et al. Alveolar macrophages from overweight/obese subjects with asthma demonstrate a proinflammatory phenotype. Am J Respir Crit Care Med 2012;186:404-411.
-
(2012)
Am J Respir Crit Care Med
, vol.186
, pp. 404-411
-
-
Lugogo, N.L.1
Hollingsworth, J.W.2
Howell, D.L.3
Que, L.G.4
Francisco, D.5
Church, T.D.6
Potts-Kant, E.N.7
Ingram, J.L.8
Wang, Y.9
Jung, S.H.10
-
39
-
-
79952593123
-
Airway and plasma leptin and adiponectin in lean and obese asthmatics and controls
-
Holguin F, Rojas M, Brown LA, Fitzpatrick AM. Airway and plasma leptin and adiponectin in lean and obese asthmatics and controls. J Asthma 2011;48:217-223.
-
(2011)
J Asthma
, vol.48
, pp. 217-223
-
-
Holguin, F.1
Rojas, M.2
Brown, L.A.3
Fitzpatrick, A.M.4
-
40
-
-
84863845758
-
Obesity in asthma: More neutrophilic inflammation as a possible explanation for a reduced treatment response
-
Telenga ED, Tideman SW, Kerstjens HA, Hacken NH, Timens W, Postma DS, van den Berge M. Obesity in asthma: more neutrophilic inflammation as a possible explanation for a reduced treatment response. Allergy 2012;67:1060-1068.
-
(2012)
Allergy
, vol.67
, pp. 1060-1068
-
-
Telenga, E.D.1
Tideman, S.W.2
Kerstjens, H.A.3
Hacken, N.H.4
Timens, W.5
Postma, D.S.6
Van Den Berge, M.7
-
41
-
-
79955601400
-
A high-fat challenge increases airway inflammation and impairs bronchodilator recovery in asthma
-
Wood LG, Garg ML, Gibson PG. A high-fat challenge increases airway inflammation and impairs bronchodilator recovery in asthma. J Allergy Clin Immunol 2011;127:1133-1140.
-
(2011)
J Allergy Clin Immunol
, vol.127
, pp. 1133-1140
-
-
Wood, L.G.1
Garg, M.L.2
Gibson, P.G.3
-
42
-
-
34247625981
-
Asymmetric dimethylarginine induces oxidative and nitrosative stress in murine lung epithelial cells
-
Wells SM, Holian A. Asymmetric dimethylarginine induces oxidative and nitrosative stress in murine lung epithelial cells. Am J Respir Cell Mol Biol 2007;36:520-528.
-
(2007)
Am J Respir Cell Mol Biol
, vol.36
, pp. 520-528
-
-
Wells, S.M.1
Holian, A.2
-
44
-
-
52749084926
-
Alterations of the arginine metabolome in asthma
-
National Heart, Lung, and Blood Institute's Severe Asthma Research Program
-
Lara A, Khatri SB, Wang Z, Comhair SA, Xu W, Dweik RA, Bodine M, Levison BS, Hammel J, Bleecker E, et al.; National Heart, Lung, and Blood Institute's Severe Asthma Research Program. Alterations of the arginine metabolome in asthma. Am J Respir Crit Care Med 2008;178:673-681.
-
(2008)
Am J Respir Crit Care Med
, vol.178
, pp. 673-681
-
-
Lara, A.1
Khatri, S.B.2
Wang, Z.3
Comhair, S.A.4
Xu, W.5
Dweik, R.A.6
Bodine, M.7
Levison, B.S.8
Hammel, J.9
Bleecker, E.10
-
45
-
-
79956371796
-
Elevated concentration of asymmetric dimethylarginine (ADMA) in individuals with metabolic syndrome
-
Palomo I, Contreras A, Alarcón LM, Leiva E, Guzmán L, Mujica V, Icaza G, Díaz N, González DR, Moore-Carrasco R. Elevated concentration of asymmetric dimethylarginine (ADMA) in individuals with metabolic syndrome. Nitric Oxide 2011;24:224-228.
-
(2011)
Nitric Oxide
, vol.24
, pp. 224-228
-
-
Palomo, I.1
Contreras, A.2
Alarcón, L.M.3
Leiva, E.4
Guzmán, L.5
Mujica, V.6
Icaza, G.7
Díaz, N.8
González, D.R.9
Moore-Carrasco, R.10
-
46
-
-
84872551287
-
Reduced L-arginine/ADMA as a potential mechanism to explain increased symptom severity and reduced atopy in late onset obese asthmatics
-
Holguin F, Comhair SA, Hazen SL, Powers RW, Khatri SS, Bleecker ER, Busse WW, Calhoun WJ, Castro M, Fitzpatrick AM, et al. Reduced L-arginine/ADMA as a potential mechanism to explain increased symptom severity and reduced atopy in late onset obese asthmatics. Am J Respir Crit Care Med 2013;187:153-159.
-
(2013)
Am J Respir Crit Care Med
, vol.187
, pp. 153-159
-
-
Holguin, F.1
Comhair, S.A.2
Hazen, S.L.3
Powers, R.W.4
Khatri, S.S.5
Bleecker, E.R.6
Busse, W.W.7
Calhoun, W.J.8
Castro, M.9
Fitzpatrick, A.M.10
-
47
-
-
37249064252
-
Pharmacokinetic and pharmacodynamic properties of oral L-citrulline and L-arginine: Impact on nitric oxide metabolism
-
Schwedhelm E, Maas R, Freese R, Jung D, Lukacs Z, Jambrecina A, Spickler W, Schulze F, Böger RH. Pharmacokinetic and pharmacodynamic properties of oral L-citrulline and L-arginine: impact on nitric oxide metabolism. Br J Clin Pharmacol 2008;65: 51-59.
-
(2008)
Br J Clin Pharmacol
, vol.65
, pp. 51-59
-
-
Schwedhelm, E.1
Maas, R.2
Freese, R.3
Jung, D.4
Lukacs, Z.5
Jambrecina, A.6
Spickler, W.7
Schulze, F.8
Böger, R.H.9
-
48
-
-
84857274709
-
Oxidative stress and antioxidant defense
-
Birben E, Sahiner UM, Sackesen C, Erzurum S, Kalayci O. Oxidative stress and antioxidant defense. World Allergy Organ J 2012;5: 9-19.
-
(2012)
World Allergy Organ J
, vol.5
, pp. 9-19
-
-
Birben, E.1
Sahiner, U.M.2
Sackesen, C.3
Erzurum, S.4
Kalayci, O.5
-
49
-
-
80455163229
-
Oxidative stress in asthma
-
Sahiner UM, Birben E, Erzurum S, Sackesen C, Kalayci O. Oxidative stress in asthma. World Allergy Organ J 2011;4:151-158.
-
(2011)
World Allergy Organ J
, vol.4
, pp. 151-158
-
-
Sahiner, U.M.1
Birben, E.2
Erzurum, S.3
Sackesen, C.4
Kalayci, O.5
-
50
-
-
80054878979
-
Nitric oxide metabolism in asthma pathophysiology
-
Ghosh S, Erzurum SC. Nitric oxide metabolism in asthma pathophysiology. Biochim Biophys Acta 2011;1810:1008-1016.
-
(2011)
Biochim Biophys Acta
, vol.1810
, pp. 1008-1016
-
-
Ghosh, S.1
Erzurum, S.C.2
-
51
-
-
84862067897
-
Glutathione redox control of asthma: From molecular mechanisms to therapeutic opportunities
-
Fitzpatrick AM, Jones DP, Brown LA. Glutathione redox control of asthma: from molecular mechanisms to therapeutic opportunities. Antioxid Redox Signal 2012;17:375-408.
-
(2012)
Antioxid Redox Signal
, vol.17
, pp. 375-408
-
-
Fitzpatrick, A.M.1
Jones, D.P.2
Brown, L.A.3
-
52
-
-
0027315107
-
Increased levels of glutathione in bronchoalveolar lavage fluid from patients with asthma
-
Smith LJ, Houston M, Anderson J. Increased levels of glutathione in bronchoalveolar lavage fluid from patients with asthma. Am Rev Respir Dis 1993;147:1461-1464.
-
(1993)
Am Rev Respir Dis
, vol.147
, pp. 1461-1464
-
-
Smith, L.J.1
Houston, M.2
Anderson, J.3
-
53
-
-
58149181699
-
Airway glutathione homeostasis is altered in children with severe asthma: Evidence for oxidant stress
-
Fitzpatrick AM, Teague WG, Holguin F, Yeh M, Brown LA. Airway glutathione homeostasis is altered in children with severe asthma: evidence for oxidant stress. J Allergy Clin Immunol 2009;123: 146-152.e8.
-
(2009)
J Allergy Clin Immunol
, vol.123
-
-
Fitzpatrick, A.M.1
Teague, W.G.2
Holguin, F.3
Yeh, M.4
Brown, L.A.5
-
54
-
-
79957849132
-
Thiol redox disturbances in children with severe asthma are associated with posttranslational modification of the transcription factor nuclear factor (erythroid-derived 2)-like 2
-
Fitzpatrick AM, Stephenson ST, Hadley GR, Burwell L, Penugonda M, Simon DM, Hansen J, Jones DP, Brown LA. Thiol redox disturbances in children with severe asthma are associated with posttranslational modification of the transcription factor nuclear factor (erythroid-derived 2)-like 2. J Allergy Clin Immunol 2011;127: 1604-1611.
-
(2011)
J Allergy Clin Immunol
, vol.127
, pp. 1604-1611
-
-
Fitzpatrick, A.M.1
Stephenson, S.T.2
Hadley, G.R.3
Burwell, L.4
Penugonda, M.5
Simon, D.M.6
Hansen, J.7
Jones, D.P.8
Brown, L.A.9
-
55
-
-
0033369168
-
Lung glutathione and oxidative stress: Implications in cigarette smoke-induced airway disease
-
Rahman I, MacNee W. Lung glutathione and oxidative stress: implications in cigarette smoke-induced airway disease. Am J Physiol 1999;277:L1067-L1088.
-
(1999)
Am J Physiol
, vol.277
-
-
Rahman, I.1
MacNee, W.2
-
56
-
-
36348987864
-
Cigarette smoke irreversibly modi fies glutathione in airway epithelial cells
-
van der Toorn M, Smit-de Vries MP, Slebos DJ, de Bruin HG, Abello N, van Oosterhout AJ, Bischoff R, Kauffman HF. Cigarette smoke irreversibly modi fies glutathione in airway epithelial cells. Am J Physiol Lung Cell Mol Physiol 2007;293:L1156-L1162.
-
(2007)
Am J Physiol Lung Cell Mol Physiol
, vol.293
-
-
Van Der Toorn, M.1
Smit-de Vries, M.P.2
Slebos, D.J.3
De Bruin, H.G.4
Abello, N.5
Van Oosterhout, A.J.6
Bischoff, R.7
Kauffman, H.F.8
-
57
-
-
80555124930
-
Denitrosylation of HDAC2 by targeting Nrf2 restores glucocorticosteroid sensitivity in macrophages from COPD patients
-
Malhotra D, Thimmulappa RK, Mercado N, Ito K, Kombairaju P, Kumar S, Ma J, Feller-Kopman D, Wise R, Barnes P, et al. Denitrosylation of HDAC2 by targeting Nrf2 restores glucocorticosteroid sensitivity in macrophages from COPD patients. J Clin Invest 2011;121:4289-4302.
-
(2011)
J Clin Invest
, vol.121
, pp. 4289-4302
-
-
Malhotra, D.1
Thimmulappa, R.K.2
Mercado, N.3
Ito, K.4
Kombairaju, P.5
Kumar, S.6
Ma, J.7
Feller-Kopman, D.8
Wise, R.9
Barnes, P.10
-
58
-
-
33947507007
-
Inactivation and nitration of human superoxide dismutase (SOD) by fluxes of nitric oxide and superoxide
-
Demicheli V, Quijano C, Alvarez B, Radi R. Inactivation and nitration of human superoxide dismutase (SOD) by fluxes of nitric oxide and superoxide. Free Radic Biol Med 2007;42:1359-1368.
-
(2007)
Free Radic Biol Med
, vol.42
, pp. 1359-1368
-
-
Demicheli, V.1
Quijano, C.2
Alvarez, B.3
Radi, R.4
-
59
-
-
22644446038
-
Correlation of systemic superoxide dismutase deficiency to airflow obstruction in asthma
-
Comhair SA, Ricci KS, Arroliga M, Lara AR, Dweik RA, Song W, Hazen SL, Bleecker ER, Busse WW, Chung KF, et al. Correlation of systemic superoxide dismutase deficiency to airflow obstruction in asthma. Am J Respir Crit Care Med 2005;172:306-313.
-
(2005)
Am J Respir Crit Care Med
, vol.172
, pp. 306-313
-
-
Comhair, S.A.1
Ricci, K.S.2
Arroliga, M.3
Lara, A.R.4
Dweik, R.A.5
Song, W.6
Hazen, S.L.7
Bleecker, E.R.8
Busse, W.W.9
Chung, K.F.10
-
60
-
-
79959982278
-
Smoking and COPD increase sputum levels of extracellular superoxide dismutase
-
Regan EA, Mazur W, Meoni E, Toljamo T, Millar J, Vuopala K, Bowler RP, Rahman I, Nicks ME, Crapo JD, et al. Smoking and COPD increase sputum levels of extracellular superoxide dismutase. Free Radic Biol Med 2011;51:726-732.
-
(2011)
Free Radic Biol Med
, vol.51
, pp. 726-732
-
-
Regan, E.A.1
Mazur, W.2
Meoni, E.3
Toljamo, T.4
Millar, J.5
Vuopala, K.6
Bowler, R.P.7
Rahman, I.8
Nicks, M.E.9
Crapo, J.D.10
-
61
-
-
8644237366
-
Manganese superoxide dismutase is increased in the airways of smokers' lungs
-
Harju T, Kaarteenaho-Wiik R, Sirviö R, Pääkkö P, Crapo JD, Oury TD, Soini Y, Kinnula VL. Manganese superoxide dismutase is increased in the airways of smokers' lungs. Eur Respir J 2004;24:765-771.
-
(2004)
Eur Respir J
, vol.24
, pp. 765-771
-
-
Harju, T.1
Kaarteenaho-Wiik, R.2
Sirviö, R.3
Pääkkö, P.4
Crapo, J.D.5
Oury, T.D.6
Soini, Y.7
Kinnula, V.L.8
-
62
-
-
33644617339
-
Increased oxidative stress and altered levels of antioxidants in chronic obstructive pulmonary disease
-
Nadeem A, Raj HG, Chhabra SK. Increased oxidative stress and altered levels of antioxidants in chronic obstructive pulmonary disease. Inflammation 2005;29:23-32.
-
(2005)
Inflammation
, vol.29
, pp. 23-32
-
-
Nadeem, A.1
Raj, H.G.2
Chhabra, S.K.3
-
63
-
-
0343953355
-
Antioxidant nutrients and pulmonary function: The Third National Health and Nutrition Examination Survey (NHANES III)
-
Hu G, Cassano PA. Antioxidant nutrients and pulmonary function: the Third National Health and Nutrition Examination Survey (NHANES III). Am J Epidemiol 2000;151:975-981.
-
(2000)
Am J Epidemiol
, vol.151
, pp. 975-981
-
-
Hu, G.1
Cassano, P.A.2
-
64
-
-
23144443138
-
Plasma concentrations of dietary and nondietary antioxidants are low in severe asthma
-
Misso NL, Brooks-Wildhaber J, Ray S, Vally H, Thompson PJ. Plasma concentrations of dietary and nondietary antioxidants are low in severe asthma. Eur Respir J 2005;26:257-264.
-
(2005)
Eur Respir J
, vol.26
, pp. 257-264
-
-
Misso, N.L.1
Brooks-Wildhaber, J.2
Ray, S.3
Vally, H.4
Thompson, P.J.5
-
65
-
-
67650266753
-
Association between antioxidant vitamins and asthma outcome measures: Systematic review and meta-analysis
-
Allen S, Britton JR, Leonardi-Bee JA. Association between antioxidant vitamins and asthma outcome measures: systematic review and meta-analysis. Thorax 2009;64:610-619.
-
(2009)
Thorax
, vol.64
, pp. 610-619
-
-
Allen, S.1
Britton, J.R.2
Leonardi-Bee, J.A.3
-
66
-
-
0035685413
-
Diet and obstructive lung diseases
-
Romieu I, Trenga C. Diet and obstructive lung diseases. Epidemiol Rev 2001;23:268-287.
-
(2001)
Epidemiol Rev
, vol.23
, pp. 268-287
-
-
Romieu, I.1
Trenga, C.2
-
67
-
-
0030684692
-
The effect of alpha-tocopherol and beta-carotene supplementation on COPD symptoms
-
Rautalahti M, Virtamo J, Haukka J, Heinonen OP, Sundvall J, Albanes D, Huttunen JK. The effect of alpha-tocopherol and beta-carotene supplementation on COPD symptoms. Am J Respir Crit Care Med 1997;156:1447-1452.
-
(1997)
Am J Respir Crit Care Med
, vol.156
, pp. 1447-1452
-
-
Rautalahti, M.1
Virtamo, J.2
Haukka, J.3
Heinonen, O.P.4
Sundvall, J.5
Albanes, D.6
Huttunen, J.K.7
-
68
-
-
84892512993
-
Nitro-fatty acids: Formation, redox signaling, and therapeutic potential
-
In press
-
Trostchansky A, Bonilla L, González-Perilli L, Rubbo H. Nitro-fatty acids: formation, redox signaling, and therapeutic potential. Antioxid Redox Signal (In press)
-
Antioxid Redox Signal
-
-
Trostchansky, A.1
Bonilla, L.2
González-Perilli, L.3
Rubbo, H.4
-
69
-
-
84866646910
-
Nitro-fatty acids as novel electrophilic ligands for peroxisome proliferator-activated receptors
-
Ferreira AM, Minarrieta L, Lamas Bervejillo M, Rubbo H. Nitro-fatty acids as novel electrophilic ligands for peroxisome proliferator-activated receptors. Free Radic Biol Med 2012;53:1654-1663.
-
(2012)
Free Radic Biol Med
, vol.53
, pp. 1654-1663
-
-
Ferreira, A.M.1
Minarrieta, L.2
Lamas Bervejillo, M.3
Rubbo, H.4
-
70
-
-
73049089496
-
Activation of vascular endothelial nitric oxide synthase and heme oxygenase-1 expression by electrophilic nitro-fatty acids
-
Khoo NK, Rudolph V, Cole MP, Golin-Bisello F, Schopfer FJ, Woodcock SR, Batthyany C, Freeman BA. Activation of vascular endothelial nitric oxide synthase and heme oxygenase-1 expression by electrophilic nitro-fatty acids. Free Radic Biol Med 2010;48: 230-239.
-
(2010)
Free Radic Biol Med
, vol.48
, pp. 230-239
-
-
Khoo, N.K.1
Rudolph, V.2
Cole, M.P.3
Golin-Bisello, F.4
Schopfer, F.J.5
Woodcock, S.R.6
Batthyany, C.7
Freeman, B.A.8
-
72
-
-
33751507586
-
Nitrated fatty acids: Endogenous anti-inflammatory signaling mediators
-
Cui T, Schopfer FJ, Zhang J, Chen K, Ichikawa T, Baker PR, Batthyany C, Chacko BK, Feng X, Patel RP, et al. Nitrated fatty acids: endogenous anti-inflammatory signaling mediators. J Biol Chem 2006;281:35686-35698.
-
(2006)
J Biol Chem
, vol.281
, pp. 35686-35698
-
-
Cui, T.1
Schopfer, F.J.2
Zhang, J.3
Chen, K.4
Ichikawa, T.5
Baker, P.R.6
Batthyany, C.7
Chacko, B.K.8
Feng, X.9
Patel, R.P.10
-
73
-
-
67149096166
-
Uncontrolled airway inflammation in lung disease represents a defect in counter-regulatory signaling
-
Planaguma A, Levy BD. Uncontrolled airway inflammation in lung disease represents a defect in counter-regulatory signaling. Future Lipidol 2008;3:697-704.
-
(2008)
Future Lipidol
, vol.3
, pp. 697-704
-
-
Planaguma, A.1
Levy, B.D.2
-
74
-
-
77952487662
-
Cyclooxygenase-2 generates anti-in flammatory mediators from omega-3 fatty acids
-
Groeger AL, Cipollina C, Cole MP, Woodcock SR, Bonacci G, Rudolph TK, Rudolph V, Freeman BA, Schopfer FJ. Cyclooxygenase-2 generates anti-in flammatory mediators from omega-3 fatty acids. Nat Chem Biol 2010;6:433-441.
-
(2010)
Nat Chem Biol
, vol.6
, pp. 433-441
-
-
Groeger, A.L.1
Cipollina, C.2
Cole, M.P.3
Woodcock, S.R.4
Bonacci, G.5
Rudolph, T.K.6
Rudolph, V.7
Freeman, B.A.8
Schopfer, F.J.9
-
75
-
-
41149116150
-
Unsaturated lipid peroxidation-derived aldehydes activate autophagy in vascular smooth-muscle cells
-
Hill BG, Haberzettl P, Ahmed Y, Srivastava S, Bhatnagar A. Unsaturated lipid peroxidation-derived aldehydes activate autophagy in vascular smooth-muscle cells. Biochem J 2008;410: 525-534.
-
(2008)
Biochem J
, vol.410
, pp. 525-534
-
-
Hill, B.G.1
Haberzettl, P.2
Ahmed, Y.3
Srivastava, S.4
Bhatnagar, A.5
-
76
-
-
20944433417
-
Effects of N-acetylcysteine on outcomes in chronic obstructive pulmonary disease (Bronchitis Randomized on NAC Cost-Utility Study, BRONCUS): A randomised placebo-controlled trial
-
Decramer M, Rutten-van Mölken M, Dekhuijzen PN, Troosters T, van Herwaarden C, Pellegrino R, van Schayck CP, Olivieri D, Del Donno M, De Backer W, et al. Effects of N-acetylcysteine on outcomes in chronic obstructive pulmonary disease (Bronchitis Randomized on NAC Cost-Utility Study, BRONCUS): a randomised placebo-controlled trial. Lancet 2005;365:1552-1560.
-
(2005)
Lancet
, vol.365
, pp. 1552-1560
-
-
Decramer, M.1
Rutten-van Mölken, M.2
Dekhuijzen, P.N.3
Troosters, T.4
Van Herwaarden, C.5
Pellegrino, R.6
Van Schayck, C.P.7
Olivieri, D.8
Del Donno, M.9
De Backer, W.10
-
78
-
-
84880047842
-
High-dose n-acetylcysteine in stable chronic obstructive pulmonary disease: The 1-year, double-blind, randomized, placebo-controlled hiace study
-
Tse HN, Raiteri L, Wong KY, Yee KS, Ng LY, Wai KY, Loo CK, Houng CM. High-dose n-acetylcysteine in stable chronic obstructive pulmonary disease: The 1-year, double-blind, randomized, placebo-controlled hiace study. Chest 2013;144:106-118.
-
(2013)
Chest
, vol.144
, pp. 106-118
-
-
Tse, H.N.1
Raiteri, L.2
Wong, K.Y.3
Yee, K.S.4
Ng, L.Y.5
Wai, K.Y.6
Loo, C.K.7
Houng, C.M.8
-
79
-
-
8144226974
-
Antioxidant supplementation and nasal inflammatory responses among young asthmatics exposed to high levels of ozone
-
Sienra-Monge JJ, Ramirez-Aguilar M, Moreno-Macias H, Reyes-Ruiz NI, Del Río-Navarro BE, Ruiz-Navarro MX, Hatch G, Crissman K, Slade R, Devlin RB, et al. Antioxidant supplementation and nasal inflammatory responses among young asthmatics exposed to high levels of ozone. Clin Exp Immunol 2004;138:317-322.
-
(2004)
Clin Exp Immunol
, vol.138
, pp. 317-322
-
-
Sienra-Monge, J.J.1
Ramirez-Aguilar, M.2
Moreno-Macias, H.3
Reyes-Ruiz, N.I.4
Del Río-Navarro, B.E.5
Ruiz-Navarro, M.X.6
Hatch, G.7
Crissman, K.8
Slade, R.9
Devlin, R.B.10
-
80
-
-
33845401487
-
GSTM1 and GSTP1 and respiratory health in asthmatic children exposed to ozone
-
Romieu I, Ramirez-Aguilar M, Sienra-Monge JJ, Moreno-Macías H, del Rio-Navarro BE, David G, Marzec J, Hernández-Avila M, London S. GSTM1 and GSTP1 and respiratory health in asthmatic children exposed to ozone. Eur Respir J 2006;28:953-959.
-
(2006)
Eur Respir J
, vol.28
, pp. 953-959
-
-
Romieu, I.1
Ramirez-Aguilar, M.2
Sienra-Monge, J.J.3
Moreno-Macías, H.4
Del Rio-Navarro, B.E.5
David, G.6
Marzec, J.7
Hernández-Avila, M.8
London, S.9
-
81
-
-
46349088492
-
Lung function loss, smoking, vitamin C intake, and polymorphisms of the glutamate-cysteine ligase genes
-
Siedlinski M, Postma DS, van Diemen CC, Blokstra A, Smit HA, Boezen HM. Lung function loss, smoking, vitamin C intake, and polymorphisms of the glutamate-cysteine ligase genes. Am J Respir Crit Care Med 2008;178:13-19.
-
(2008)
Am J Respir Crit Care Med
, vol.178
, pp. 13-19
-
-
Siedlinski, M.1
Postma, D.S.2
Van Diemen, C.C.3
Blokstra, A.4
Smit, H.A.5
Boezen, H.M.6
|