High-fructose corn syrup enhances intestinal tumor growth in mice

Science

Volumn 363, Issue 6433, 2019, Pages 1345-1349

  Goncalves, Marcus D ^a   Lu, Changyuan ^a   Tutnauer, Jordan ^a   Hartman, Travis E ^a   Hwang, Seo Kyoung ^a   Murphy, Charles J ^a   Pauli, Chantal ^b   Morris, Roxanne ^a   Taylor, Sam ^a   Bosch, Kaitlyn ^c   Yang, Sukjin ^d   Wang, Yumei ^d   Van Riper, Justin ^d   Carl Lekaye, H ^e   Roper, Jatin ^f   Kim, Young ^g   Chen, Qiuying ^a   Gross, Steven S ^a   Rhee, Kyu Y ^a   Cantley, Lewis C ^a   Yun, Jihye ^d   more..

^a WEILL CORNELL MEDICAL COLLEGE   (United States)

^b UNIVERSITY HOSPITAL ZURICH   (Switzerland)

^c MOUNT SINAI SCHOOL OF MEDICINE   (United States)

^d BAYLOR COLLEGE OF MEDICINE   (United States)

^e MEMORIAL SLOAN KETTERING CANCER CENTER   (United States)

^f DUKE UNIVERSITY SCHOOL OF MEDICINE   (United States)

^g Chonnam National University   (South Korea)

Author keywords

[No Author keywords available]

Indexed keywords

6 PHOSPHOFRUCTOKINASE; CORN SYRUP; FRUCTOSE 1 PHOSPHATE; GLUCOSE 6 PHOSPHATE; GLUCOSE TRANSPORTER 5; GLYCERALDEHYDE 3 PHOSPHATE DEHYDROGENASE; SODIUM GLUCOSE COTRANSPORTER; ADENOMATOUS POLYPOSIS COLI PROTEIN, MOUSE; APC PROTEIN;

CANCER; CHEMICAL REACTION; CONCENTRATION (COMPOSITION); DOSE-RESPONSE RELATIONSHIP; FATTY ACID; GLUCOSE; GROWTH; OBESITY; RODENT; SUGAR; TUMOR;

ANALYSIS OF VARIANCE; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CALORIC INTAKE; CANCER GRADING; CARCINOGENESIS; COLON POLYPOSIS; COLORECTAL CANCER; CONTROLLED STUDY; ENZYME ACTIVITY; FATTY ACID SYNTHESIS; FRUCTOSE METABOLISM; GENETIC ENGINEERING; GLUCOSE METABOLISM; GLUCOSE TRANSPORT; GLYCOLYSIS; INTESTINE; LIPID METABOLISM; LIPOGENESIS; LIQUID CHROMATOGRAPHY-MASS SPECTROMETRY; MOUSE; NONHUMAN; OBESITY; PRIORITY JOURNAL; PROTEIN CLEAVAGE; PROTEIN DEGRADATION; PROTEIN DEPLETION; PROTEIN PHOSPHORYLATION; RADIOACTIVITY; SIGNAL TRANSDUCTION; TUMOR VOLUME; WNT SIGNALING; ANIMAL; DIET; GENETICS; INTESTINE TUMOR; MUTANT MOUSE STRAIN; PATHOLOGY;

MUS; ZEA MAYS;

ADENOMATOUS POLYPOSIS COLI PROTEIN; ANIMALS; CARCINOGENESIS; DIET; HIGH FRUCTOSE CORN SYRUP; INTESTINAL NEOPLASMS; MICE; MICE, MUTANT STRAINS; NEOPLASM GRADING; TUMOR BURDEN;

EID: 85063661893     PISSN: 00368075     EISSN: 10959203     Source Type: Journal    
DOI: 10.1126/science.aat8515     Document Type: Article

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