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Volumn 8, Issue 3, 2010, Pages

Scientific Opinion on the safety of sucrose esters of fatty acids prepared from vinyl esters of fatty acids and on the extension of use of sucrose esters of fatty acids in flavourings
[No Author Info available]

Author keywords

acetaldehyde; E473; emulsifier; food additive; manufacturing method; stabiliser; Sucrose monoesters of fatty acids; vinyl esters of fatty acids

Indexed keywords


EID: 85062805328     PISSN: None     EISSN: 18314732     Source Type: Journal    
DOI: 10.2903/j.efsa.2010.1512     Document Type: Article
Times cited : (17)

References (58)
  • 1
    • 0032718355 scopus 로고    scopus 로고
    • Interspecies variations in fatty acid hydroylations involving cytochromes P450 2E1 and 4A
    • Adas F, Berthou F, Salaün JP, Dréano Y, Amet Y, 1999. Interspecies variations in fatty acid hydroylations involving cytochromes P450 2E1 and 4A. Toxicology Letters 110, 43–45.
    • (1999) Toxicology Letters , vol.110 , pp. 43-45
    • Adas, F.1    Berthou, F.2    Salaün, J.P.3    Dréano, Y.4    Amet, Y.5
  • 2
    • 84982343154 scopus 로고
    • The stability of sucrose monolaurate: rate of formation of lauric acid
    • Anderson RA, Polack AE, 1968. The stability of sucrose monolaurate: rate of formation of lauric acid. Journal of Pharmacy and Pharmacology 20, 249–254.
    • (1968) Journal of Pharmacy and Pharmacology , vol.20 , pp. 249-254
    • Anderson, R.A.1    Polack, A.E.2
  • 4
    • 0344738783 scopus 로고    scopus 로고
    • Stearic acid absorption and its metabolizable energy value are minimally lower than those of other fatty acids in healthy men fed mixed diets
    • Baer DJ, Judd JT, Kris-Etherton PM, Zhao G, Emken EA, 2003. Stearic acid absorption and its metabolizable energy value are minimally lower than those of other fatty acids in healthy men fed mixed diets. Journal of Nutrition 133, 4129–4134.
    • (2003) Journal of Nutrition , vol.133 , pp. 4129-4134
    • Baer, D.J.1    Judd, J.T.2    Kris-Etherton, P.M.3    Zhao, G.4    Emken, E.A.5
  • 5
    • 65649153648 scopus 로고    scopus 로고
    • Assessment of dietary exposure to thirteen selected food additives colours, preservatives, antioxidants, stabilisers and emulsifiers and sweeteners in the French population
    • Volume, Issue
    • Bemrah N, Leblanc J-Ch and Volatier J-L, 2008. Assessment of dietary exposure to thirteen selected food additives colours, preservatives, antioxidants, stabilisers and emulsifiers and sweeteners in the French population. Food Additives and Contaminants, Part B, Volume 1, Issue 1, 2–14
    • (2008) Food Additives and Contaminants, Part B , vol.1 , Issue.1 , pp. 2-14
    • Bemrah, N.1    Leblanc, J.-C.2    Volatier, J.-L.3
  • 6
    • 0036637157 scopus 로고    scopus 로고
    • Distinction between esterases and lipases: A kinetic study with vinyl esters and TAG
    • Chahinian H, Nini L, Roitard E, Dubes JP, Comeau LC, Sarda L, 2002. Distinction between esterases and lipases: A kinetic study with vinyl esters and TAG. Lipids 37, 653–662.
    • (2002) Lipids , vol.37 , pp. 653-662
    • Chahinian, H.1    Nini, L.2    Roitard, E.3    Dubes, J.P.4    Comeau, L.C.5    Sarda, L.6
  • 8
    • 0023616241 scopus 로고
    • Final report on the safety assessment of oleic acid, lauric acid, palmitic acid, myristic acid, and stearic acid
    • CIR, 1987. Final report on the safety assessment of oleic acid, lauric acid, palmitic acid, myristic acid, and stearic acid. Journal of the American College of Sports Medicine 6, 321–401.
    • (1987) Journal of the American College of Sports Medicine , vol.6 , pp. 321-401
  • 10
    • 85078393364 scopus 로고    scopus 로고
    • Commission Directive 2008/84/EC of 27 August 2008 laying down specific purity criteria on food additives other than colours and sweeteners, 20.09
    • Commission Directive 2008/84/EC of 27 August 2008 laying down specific purity criteria on food additives other than colours and sweeteners. Official Journal L 253, 20.09.2008.
    • (2008) Official Journal L , vol.253
  • 11
    • 85078385298 scopus 로고    scopus 로고
    • . Available from
    • Crème Software Limited (2005–2009). Available from www.cremesoftware.com/
    • (2005)
  • 12
    • 0036281181 scopus 로고    scopus 로고
    • Mechanisms of cytoprotective effect of amino acids on local toxicity caused by sodium laurate, a drug absorption enhancer, in intestinal epithelium
    • Endo Y, Hanada K, Miyake M, Ogawara K-I, Higaki K, Kimura T, 2002. Mechanisms of cytoprotective effect of amino acids on local toxicity caused by sodium laurate, a drug absorption enhancer, in intestinal epithelium. The Journal of Pharmaceutical Sciences 91 (3), 730–743.
    • (2002) The Journal of Pharmaceutical Sciences , vol.91 , Issue.3 , pp. 730-743
    • Endo, Y.1    Hanada, K.2    Miyake, M.3    Ogawara, K.-I.4    Higaki, K.5    Kimura, T.6
  • 13
    • 79958834001 scopus 로고    scopus 로고
    • Draft of 04.05.2005, 112., European Chemicals Bureau
    • ECB (European Chemicals Bureau), 2005. Draft Risk Assessment Report Vinyl acetate. Draft of 04.05.2005, 112. European Chemicals Bureau. Available at: ecb.jrc.ec.europa.eu/DOCUMENTS/Existing-Chemicals/RISK_ASSESSMENT/DRAFT/R059_0807_env_hh.pdf
    • (2005) Draft Risk Assessment Report Vinyl acetate
  • 14
    • 34548254125 scopus 로고    scopus 로고
    • Task 4.2. Report on Methodologies for the Monitoring of Food Additive Intake across the European Union. DG Industry
    • EC (European Commission), 1997. Reports on Tasks for scientific co-operation. Task 4.2. Report on Methodologies for the Monitoring of Food Additive Intake across the European Union. DG Industry
    • (1997) Reports on Tasks for scientific co-operation
  • 17
    • 33750473420 scopus 로고    scopus 로고
    • Opinion of the Scientific Panel on food additives, flavourings, processing aids and material in contact with food (AFC) on sucrose esters fatty acids, E473 and glucoglycerides, E474 based on a request from the Commission related to sucrose esters of fatty acids (E 473)
    • Modified on 25 January 2006
    • EFSA (European Food Safety Authority), 2004. Opinion of the Scientific Panel on food additives, flavourings, processing aids and material in contact with food (AFC) on sucrose esters fatty acids, E473 and glucoglycerides, E474 based on a request from the Commission related to sucrose esters of fatty acids (E 473). The EFSA Journal 106, 1–24. Modified on 25 January 2006.
    • (2004) The EFSA Journal , vol.106 , pp. 1-24
  • 20
    • 0012659679 scopus 로고
    • On the fate of complex esters of vinyl alcohol and fatty acids in the organism
    • Filov VA, 1959. On the fate of complex esters of vinyl alcohol and fatty acids in the organism. Gigiena Truda I Proressional'nye Zabolevaniya 3, 42–46.
    • (1959) Gigiena Truda I Proressional'nye Zabolevaniya , vol.3 , pp. 42-46
    • Filov, V.A.1
  • 22
    • 0031820173 scopus 로고    scopus 로고
    • Carcinogenicity of antioxidants BHA, caffeic acid, sesamol, p-methoxyphenol and catechol at low doses, either alone or in combination and modulation of their effects in a rat medium term multi organ carcinogenesis model
    • Hirose M, Takesada Y, Tanaka H, Tamano S, Kato T, Shirai T, 1997. Carcinogenicity of antioxidants BHA, caffeic acid, sesamol, p-methoxyphenol and catechol at low doses, either alone or in combination and modulation of their effects in a rat medium term multi organ carcinogenesis model. Carcinogenesis 19, 207–212.
    • (1997) Carcinogenesis , vol.19 , pp. 207-212
    • Hirose, M.1    Takesada, Y.2    Tanaka, H.3    Tamano, S.4    Kato, T.5    Shirai, T.6
  • 23
    • 85078370804 scopus 로고    scopus 로고
    • IARC (International Agency for Research on Cancer), 2009. Press release no. 196. www.iarc.fr/en/media-centre/pr/2009/pdfs/pr196_E.pdf
    • (2009) Press release no. 196
  • 26
    • 84918381818 scopus 로고
    • Studies on digestibility of sucrose ester of stearic acid in rat
    • Ishizuka T and Nakamura S, 1974. Studies on digestibility of sucrose ester of stearic acid in rat. Eivo to Shokuryo 27, 65–70.
    • (1974) Eivo to Shokuryo , vol.27 , pp. 65-70
    • Ishizuka, T.1    Nakamura, S.2
  • 27
    • 85078384089 scopus 로고    scopus 로고
    • th session, Rome, 17–26 June 1997
    • Add. 5, Food and Agriculture Organization of the United Nations, Rome, pp
    • th session, Rome, 17–26 June 1997. Sucrose esters of fatty acids. FAO Food and Nutrition Paper, 52, Add. 5, Food and Agriculture Organization of the United Nations, Rome, pp 173–181.
    • (1997) Sucrose esters of fatty acids. FAO Food and Nutrition Paper , vol.52 , pp. 173-181
  • 28
    • 85078380999 scopus 로고    scopus 로고
    • Prepared at the 68, JECFAand published in FAO JECFA Monographs 4 (2007). Available from
    • th JECFA (2007) and published in FAO JECFA Monographs 4 (2007). Available from www.fao.org/ag/agn/jecfa-additives/specs/monograph4/additive-447-m4.pdf
    • (2007) Sucrose esters of fatty acids , Issue.2007
  • 29
    • 85078384261 scopus 로고    scopus 로고
    • Issued 1 July 2009. JECFA/71/SC. Available from
    • JECFA (Joint FAO/WHO Expert Committee on Food Additives), 2009. The Summary report of the 71st JECFA meeting, 16 - 24 June 2009. Issued 1 July 2009. JECFA/71/SC. Available from: www.fao.org/ag/agn/agns/jecfa/JECFA71_Summary_report_final.pdf
    • (2009) The Summary report of the 71st JECFA meeting, 16 - 24 June 2009
  • 30
    • 0014984254 scopus 로고
    • Follicular-keratogenic properties of fatty acids in the external ear canal of the rabbit
    • Kanaar P, 1971. Follicular-keratogenic properties of fatty acids in the external ear canal of the rabbit. Dermatologica, 142 (1), 14–22.
    • (1971) Dermatologica , vol.142 , Issue.1 , pp. 14-22
    • Kanaar, P.1
  • 31
    • 0038143617 scopus 로고    scopus 로고
    • Differential modulation of Toll-like receptors by fatty acids: preferential inhibition by n-3 polyunsaturated fatty acids
    • Lee JY, Plakidas A, Lee WH, Heikkinen A, Chanmugam P, Bray G and Hwang DH, 2003a. Differential modulation of Toll-like receptors by fatty acids: preferential inhibition by n-3 polyunsaturated fatty acids. Journal of Lipid Research 44, 479–486.
    • (2003) Journal of Lipid Research , vol.44 , pp. 479-486
    • Lee, J.Y.1    Plakidas, A.2    Lee, W.H.3    Heikkinen, A.4    Chanmugam, P.5    Bray, G.6    Hwang, D.H.7
  • 34
    • 0031587527 scopus 로고    scopus 로고
    • Results of a long-term experimental study on the carcinogenicity of vinyl acetate monomer in mice
    • Maltoni C, Ciliberti A, Lefemine G, Soffritti M, 1997. Results of a long-term experimental study on the carcinogenicity of vinyl acetate monomer in mice. Annals New York Academy of Sciences 837, 209–38
    • (1997) Annals New York Academy of Sciences , vol.837 , pp. 209-238
    • Maltoni, C.1    Ciliberti, A.2    Lefemine, G.3    Soffritti, M.4
  • 40
    • 0029143201 scopus 로고
    • Chemoprevention of axoxymethane-induced colon cancer by ascorbylpalmitate, carbenoxolone, dimethylfumarate and p-methoxyphenol in male F344 rats
    • Rao CV, Rivenson A, Kelloff GJ, Reddy BS, 1995. Chemoprevention of axoxymethane-induced colon cancer by ascorbylpalmitate, carbenoxolone, dimethylfumarate and p-methoxyphenol in male F344 rats. Anticancer Research 15, 1199–1204.
    • (1995) Anticancer Research , vol.15 , pp. 1199-1204
    • Rao, C.V.1    Rivenson, A.2    Kelloff, G.J.3    Reddy, B.S.4
  • 41
    • 0022976720 scopus 로고
    • The anticlastogenic potential of fatty acid methyl esters
    • Renner HW, 1986. The anticlastogenic potential of fatty acid methyl esters. Mutation Research 172, 265–269.
    • (1986) Mutation Research , vol.172 , pp. 265-269
    • Renner, H.W.1
  • 42
    • 1142299678 scopus 로고    scopus 로고
    • Although it is rapidly metabolized in cultured rat hepatocytes, lauric acid is used for protein acylation
    • Rioux V, Daval S, Guillou H, Jan H, LeGrand P, 2003. Although it is rapidly metabolized in cultured rat hepatocytes, lauric acid is used for protein acylation. Reproduction Nutrition Development 43, 419–430.
    • (2003) Reproduction Nutrition Development , vol.43 , pp. 419-430
    • Rioux, V.1    Daval, S.2    Guillou, H.3    Jan, H.4    LeGrand, P.5
  • 44
    • 85078382221 scopus 로고
    • Commission of the European Communites, Directorate-General for Internal market and industrial affairs. Opinion on sucroglycerides and sucrose esters, point 7.2
    • rd Meeting of the Scientific Committee for Food held on 10 April 1992 in Brussels. Commission of the European Communites, Directorate-General for Internal market and industrial affairs. Opinion on sucroglycerides and sucrose esters, point 7.2.
    • (1992) rd Meeting of the Scientific Committee for Food held on 10 April 1992 in Brussels
  • 46
    • 33646835962 scopus 로고    scopus 로고
    • Estimation of sucrose esters in foods using gas chromatography-mass spectrometry
    • Scotter MJ, Castle L and Roberts PDT, 2006. Estimation of sucrose esters in foods using gas chromatography-mass spectrometry. Food Additives and Contaminants: Part A, 23 (6), 539–546.
    • (2006) Food Additives and Contaminants: Part A , vol.23 , Issue.6 , pp. 539-546
    • Scotter, M.J.1    Castle, L.2    Roberts, P.D.T.3
  • 50
    • 0036549852 scopus 로고    scopus 로고
    • Chronic toxicity and carcinogenicity of sucrose fatty acid esters in Fischer 344/DuCrj rats
    • Takeda K and Flood M, 2002. Chronic toxicity and carcinogenicity of sucrose fatty acid esters in Fischer 344/DuCrj rats. Regulatory Toxicology and Pharmacology, 35, 157–164.
    • (2002) Regulatory Toxicology and Pharmacology , vol.35 , pp. 157-164
    • Takeda, K.1    Flood, M.2
  • 52
    • 0025028879 scopus 로고
    • Para-methoxyphenolstrongly stimulates cell proliferation in the rat forestomach but is not a promoter of rat forestomach carcinogenesis
    • Wada S, Hirose M, Takahashi S, Okazaki S, Ito N, 1990. Para-methoxyphenolstrongly stimulates cell proliferation in the rat forestomach but is not a promoter of rat forestomach carcinogenesis. Carcinogenesis 11, 1891–1894.
    • (1990) Carcinogenesis , vol.11 , pp. 1891-1894
    • Wada, S.1    Hirose, M.2    Takahashi, S.3    Okazaki, S.4    Ito, N.5
  • 53
    • 17844391306 scopus 로고    scopus 로고
    • Saturated and polyunsaturated fatty acids reciprocally modulate dendritic cell functions mediated through TLR4
    • Wheatherill AR, Lee JY, Lemay DG, Youn HS, Hwang DH., 2005. Saturated and polyunsaturated fatty acids reciprocally modulate dendritic cell functions mediated through TLR4. The Journal of Immunology, 174 (9): 5390–5397.
    • (2005) The Journal of Immunology , vol.174 , Issue.9 , pp. 5390-5397
    • Wheatherill, A.R.1    Lee, J.Y.2    Lemay, D.G.3    Youn, H.S.4    Hwang, D.H.5
  • 55
    • 0003794616 scopus 로고    scopus 로고
    • Saturated aliphatic linear primary alcohols, aldehydes and acids. Prepared by the forty-ninth meeting of the Joint FAO/WHO Expert Committee on Food Additives (JECFA). WHO Food Additives Series, 40. Available from
    • WHO (World Health Organisation), 1998. Safety evaluation of certain food additives and contaminants. Saturated aliphatic linear primary alcohols, aldehydes and acids. Prepared by the forty-ninth meeting of the Joint FAO/WHO Expert Committee on Food Additives (JECFA). WHO Food Additives Series, No. 40. Available from: www.inchem.org/documents/jecfa/jecmono/v040je10.htm
    • (1998) Safety evaluation of certain food additives and contaminants
  • 56
    • 70350482557 scopus 로고    scopus 로고
    • Fatty acids modulate Toll-like receptor 4 activation through regulation of receptor dimerization and recruitment into lipid rafts in a reactive oxygen species-dependent manner
    • Wong WS, Kwon M-J, Choi AM K, Kim H-P, Nakahira K and Hwang DH, 2009. Fatty acids modulate Toll-like receptor 4 activation through regulation of receptor dimerization and recruitment into lipid rafts in a reactive oxygen species-dependent manner. The Journal of Biological Chemistry 284 (40), 27384–27392.
    • (2009) The Journal of Biological Chemistry , vol.284 , Issue.40 , pp. 27384-27392
    • Wong, W.S.1    Kwon, M.-J.2    Choi AM, K.3    Kim, H.-P.4    Nakahira, K.5    Hwang, D.H.6
  • 57
    • 0034757027 scopus 로고    scopus 로고
    • Amino acids protect epithelial cells from the local toxicity by absorption enhancer, sodium laurate
    • Yata T, Endo Y, Sone M, Ogawara K-I, Higaki K and Kimura T, 2001. Amino acids protect epithelial cells from the local toxicity by absorption enhancer, sodium laurate. The Journal of Pharmaceutical Science 90 (8), 1456–1465.
    • (2001) The Journal of Pharmaceutical Science , vol.90 , Issue.8 , pp. 1456-1465
    • Yata, T.1    Endo, Y.2    Sone, M.3    Ogawara, K.-I.4    Higaki, K.5    Kimura, T.6


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