Mechanisms underpinning the polypharmacy effects of medications in psychiatry

International Journal of Neuropsychopharmacology

Volumn 21, Issue 6, 2018, Pages 582-591

  Bortolasci, Chiara C ^a,b   Spolding, Briana ^a   Callaly, Edward ^a   Martin, Sheree ^a   Panizzutti, Bruna ^c   Kidnapillai, Srisaiyini ^a   Connor, Timothy ^a   Hasebe, Kyoko ^a   Mohebbi, Mohammadreza ^a   Dean, Olivia M ^a,d,e   McGee, Sean L ^a   Dodd, Seetal ^a,d,f   Gray, Laura ^a,d   Berk, Michael ^a,d,e,f   Walder, Ken ^a  

^a DEAKIN UNIVERSITY   (Australia)

^b STATE UNIVERSITY OF LONDRINA   (Brazil)

^c HOSPITAL DE CLÍNICAS DE PORTO ALEGRE   (Brazil)

^d FLOREY INSTITUTE OF NEUROSCIENCE AND MENTAL HEALTH   (Australia)

^e UNIVERSITY OF MELBOURNE   (Australia)

^f THE NATIONAL CENTRE OF EXCELLENCE IN YOUTH MENTAL HEALTH   (Australia)

Author keywords

Bipolar disorder; Inflammation; Mitochondrial function; Polypharmacy; Psychiatry

Indexed keywords

ATP SYNTHASE H TRANSPORTING MITOCHONDRIAL F1 COMPLEX ALPHA SUBUNIT; EOTAXIN; GAMMA INTERFERON; GRANULOCYTE COLONY STIMULATING FACTOR; GRANULOCYTE MACROPHAGE COLONY STIMULATING FACTOR; INTERLEUKIN 10; INTERLEUKIN 12P40; INTERLEUKIN 12P70; INTERLEUKIN 13; INTERLEUKIN 17; INTERLEUKIN 1ALPHA; INTERLEUKIN 1BETA; INTERLEUKIN 3; INTERLEUKIN 4; INTERLEUKIN 5; INTERLEUKIN 6; LAMOTRIGINE; LITHIUM; PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR GAMMA COACTIVATOR 1ALPHA; PROTON TRANSPORTING ADENOSINE TRIPHOSPHATE SYNTHASE; QUETIAPINE; RANTES; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE DEHYDROGENASE (UBIQUINONE); SUCCINATE DEHYDROGENASE; TUMOR NECROSIS FACTOR; UBIQUINOL CYTOCHROME C REDUCTASE; UNCLASSIFIED DRUG; VALPROIC ACID; CYTOKINE; LIPOPOLYSACCHARIDE; TRANQUILIZER;

ARTICLE; CONTROLLED STUDY; CYTOKINE RELEASE; DRUG MECHANISM; GENE OVEREXPRESSION; HUMAN; HUMAN CELL; INFLAMMATION; METABOLIC FLUX ANALYSIS; MICROGLIA; POLYPHARMACY; PRIORITY JOURNAL; PSYCHOPHARMACOLOGY; PSYCHOPHARMACOTHERAPY; REAL TIME POLYMERASE CHAIN REACTION; ANIMAL; BIPOLAR DISORDER; CELL LINE; DRUG EFFECT; DRUG INTERACTION; GENE EXPRESSION; METABOLISM; MITOCHONDRION; MOUSE; NERVE CELL;

ANIMALS; ANTIMANIC AGENTS; BIPOLAR DISORDER; CELL LINE; CYTOKINES; DRUG INTERACTIONS; GENE EXPRESSION; HUMANS; INFLAMMATION; LIPOPOLYSACCHARIDES; MICE; MICROGLIA; MITOCHONDRIA; NEURONS; POLYPHARMACY;

EID: 85061549053     PISSN: 14611457     EISSN: 14695111     Source Type: Journal    
DOI: 10.1093/ijnp/pyy014     Document Type: Article

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