Interferon lambda protects the female reproductive tract against Zika virus infection

Nature Communications

Volumn 10, Issue 1, 2019, Pages

  Caine, Elizabeth A ^a   Scheaffer, Suzanne M ^a   Arora, Nitin ^b,c,e   Zaitsev, Konstantin ^a,d   Artyomov, Maxim N ^a   Coyne, Carolyn B ^b,c   Moley, Kelle H ^a   Diamond, Michael S ^a  

^a WASHINGTON UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b UNIVERSITY OF PITTSBURGH SCHOOL OF MEDICINE   (United States)

^c CHILDREN S HOSPITAL OF PITTSBURGH   (United States)

^d ITMO UNIVERSITY   (Russian Federation)

^e University of Alabama at Birmingham   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ALPHA INTERFERON; BETA INTERFERON; ESTRADIOL; INTERFERON; LAMBDA INTERFERON; PROGESTERONE; UNCLASSIFIED DRUG; ANTIVIRUS AGENT; IL28A PROTEIN, HUMAN; INTERLEUKIN DERIVATIVE;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANTIVIRAL ACTIVITY; ARTICLE; CONTROLLED STUDY; FEMALE; FEMALE GENITAL SYSTEM; HORMONAL THERAPY; HOST RESISTANCE; HUMAN; HUMAN CELL; IMMUNOTHERAPY; MOUSE; NONHUMAN; SEXUAL TRANSMISSION; UTERINE CERVIX EPITHELIUM; VAGINA EPITHELIUM; VAGINAL LAVAGE; ZIKA FEVER; ANIMAL; C57BL MOUSE; CYTOLOGY; DISEASE MODEL; DRUG EFFECT; EPITHELIUM CELL; HOST PATHOGEN INTERACTION; IMMUNOLOGY; INTRAVAGINAL DRUG ADMINISTRATION; PATHOGENICITY; PRIMARY CELL CULTURE; SEXUALLY TRANSMITTED DISEASE; TRANSMISSION; UTERINE CERVIX; VAGINA; VIROLOGY; VIRUS REPLICATION; ZIKA VIRUS;

ADMINISTRATION, INTRAVAGINAL; ANIMALS; ANTIVIRAL AGENTS; CERVIX UTERI; DISEASE MODELS, ANIMAL; EPITHELIAL CELLS; ESTRADIOL; FEMALE; HOST-PATHOGEN INTERACTIONS; HUMANS; INTERFERON-ALPHA; INTERFERON-BETA; INTERLEUKINS; MICE; MICE, INBRED C57BL; PRIMARY CELL CULTURE; PROGESTERONE; SEXUALLY TRANSMITTED DISEASES, VIRAL; VAGINA; VIRUS REPLICATION; ZIKA VIRUS; ZIKA VIRUS INFECTION;

EID: 85060132884     PISSN: None     EISSN: 20411723     Source Type: Journal    
DOI: 10.1038/s41467-018-07993-2     Document Type: Article

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