Gestational Stage and IFN-λ Signaling Regulate ZIKV Infection In Utero

Cell Host and Microbe

Volumn 22, Issue 3, 2017, Pages 366-376.e3

  Jagger, Brett W ^a   Miner, Jonathan J ^a   Cao, Bin ^a   Arora, Nitin ^b   Smith, Amber M ^a   Kovacs, Attila ^a   Mysorekar, Indira U ^a   Coyne, Carolyn B ^b   Diamond, Michael S ^a  

^a WASHINGTON UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b CHILDREN S HOSPITAL OF PITTSBURGH   (United States)

Author keywords

flavivirus; gestational stage; host immunity; innate immunity; interferon lambda; pathogenesis; pregnancy; Zika virus

Indexed keywords

CYTOKERATIN 19; HUMAN PLACENTA LACTOGEN; INTERFERON; INTERFERON LAMBDA; UNCLASSIFIED DRUG; VIRUS RNA; ZIKA VIRUS RNA; CYTOKINE; IFNLR1 PROTEIN, MOUSE; INTERFERON RECEPTOR; INTERFERON-LAMBDA PROTEIN, MOUSE;

ABDOMINAL CIRCUMFERENCE; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CHORION VILLUS; CONTROLLED STUDY; CROWN RUMP LENGTH; DECIDUA; EXPLANT; FEMALE; FETUS; FETUS MEMBRANE; FETUS TISSUE; GESTATIONAL AGE; IN SITU HYBRIDIZATION; MOUSE; NONHUMAN; PATHOGENESIS; PHENOTYPE; PLACENTA INSUFFICIENCY; PLACENTAL TRANSFER; PREGNANCY; PRIORITY JOURNAL; REPRODUCTION; SIGNAL TRANSDUCTION; SYNCYTIOTROPHOBLAST; VERTICAL TRANSMISSION; VIRUS LOAD; VIRUS REPLICATION; ZIKA FEVER; ANIMAL; C57BL MOUSE; DISEASE MODEL; EMBRYOLOGY; FETUS DISEASE; GENETICS; HUMAN; MALE; METABOLISM; PATHOPHYSIOLOGY; PHYSIOLOGY; PREGNANCY COMPLICATION; VIROLOGY; ZIKA VIRUS;

ANIMALS; CYTOKINES; DISEASE MODELS, ANIMAL; FEMALE; FETAL DISEASES; GESTATIONAL AGE; HUMANS; MALE; MICE; MICE, INBRED C57BL; PREGNANCY; PREGNANCY COMPLICATIONS, INFECTIOUS; RECEPTORS, INTERFERON; ZIKA VIRUS; ZIKA VIRUS INFECTION;

EID: 85030850112     PISSN: 19313128     EISSN: 19346069     Source Type: Journal    
DOI: 10.1016/j.chom.2017.08.012     Document Type: Article

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