Organotypic models of type III interferon-mediated protection from Zika virus infections at the maternal–fetal interface

Proceedings of the National Academy of Sciences of the United States of America

Volumn 114, Issue 35, 2017, Pages 9433-9438

  Corry, Jacqueline ^a,b   Arora, Nitin ^a,b   Good, Charles A ^a,b   Sadovsky, Yoel ^a,c   Coyne, Carolyn B ^a,b  

^a UNIVERSITY OF PITTSBURGH SCHOOL OF MEDICINE   (United States)

^b CHILDREN S HOSPITAL OF PITTSBURGH   (United States)

^c UNIVERSITY OF PITTSBURGH   (United States)

Author keywords

Organotypic models; Placenta; Trophoblast; Type III interferon; Zika virus

Indexed keywords

CYTOKERATIN 19; GAMMA INTERFERON 1; GAMMA INTERFERON 2; INTERFERON; INTERFERON TYPE III; PLACENTA PROTEIN 5; PREGNANCY ASSOCIATED PROTEIN; RUXOLITINIB; UNCLASSIFIED DRUG; VIRUS RNA; PYRAZOLE DERIVATIVE;

ANTIVIRAL ACTIVITY; ARTICLE; BIOREACTOR; CAPILLARY ENDOTHELIAL CELL; CELL CULTURE; CHORION VILLUS; COCULTURE; CONDITIONED MEDIUM; CONTROLLED STUDY; CULTURE MEDIUM; CYTOKINE RELEASE; EXPLANT; FEMALE; FIBROBLAST; HUMAN; HUMAN CELL; HUMAN TISSUE; IMMUNOFLUORESCENCE MICROSCOPY; IMMUNOFLUORESCENCE TEST; MATERNAL BLOOD; MOTHER FETUS RELATIONSHIP; PARACRINE SIGNALING; PHENOTYPE; PLACENTA; PRIMARY CELL CULTURE; PRIORITY JOURNAL; QUANTITATIVE ANALYSIS; RETROVIRIDAE; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; RNA SEQUENCE; SECOND TRIMESTER PREGNANCY; SYNCYTIOTROPHOBLAST CELL; THREE DIMENSIONAL IMAGING; TROPHOBLAST; VERTICAL TRANSMISSION; VIRUS PARTICLE; ZIKA FEVER; CELL LINE; IMMUNOLOGY; PHYSIOLOGY; VIROLOGY; ZIKA VIRUS;

CELL LINE; FIBROBLASTS; HUMANS; MATERNAL-FETAL RELATIONS; PYRAZOLES; ZIKA VIRUS; ZIKA VIRUS INFECTION;

EID: 85028530634     PISSN: 00278424     EISSN: 10916490     Source Type: Journal    
DOI: 10.1073/pnas.1707513114     Document Type: Article

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