Spatiotemporal transcriptomic divergence across human and macaque brain development

Science

Volumn 362, Issue 6420, 2018, Pages

  Zhu, Ying ^a,b   Sousa, André M M ^a   Gao, Tianliuyun ^a   Skarica, Mario ^a   Li, Mingfeng ^a   Santpere, Gabriel ^a   Esteller Cucala, Paula ^c   Juan, David ^c   Ferrández Peral, Luis ^c   Gulden, Forrest O ^a   Yang, Mo ^a   Miller, Daniel J ^a   Marques Bonet, Tomas ^c,d,e,f   Kawasawa, Yuka Imamura ^g   Zhao, Hongyu ^b   Sestan, Nenad ^a,h  

^a YALE UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b YALE UNIVERSITY   (United States)

^c Barcelona Biomedical Research Park   (Spain)

^d INSTITUCIÓ CATALANA DE RECERCA I ESTUDIS AVANÇATS ICREA   (Spain)

^e CENTRE FOR GENOMIC REGULATION CRG   (Spain)

^f UNIVERSITAT AUTÒNOMA DE BARCELONA   (Spain)

^g PENN STATE COLLEGE OF MEDICINE   (United States)

^h YALE UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

AUTISM; BRAIN; CELL COMPONENT; DEVELOPMENTAL BIOLOGY; EVOLUTION; NERVOUS SYSTEM; RNA; SPATIOTEMPORAL ANALYSIS;

ANIMAL CELL; ANIMAL TISSUE; ARTICLE; AUTISM; BRAIN DEVELOPMENT; BRAIN REGION; COMPARATIVE STUDY; CONTROLLED STUDY; CORPUS STRIATUM; DORSOLATERAL PREFRONTAL CORTEX; EMBRYO; EMBRYO DEVELOPMENT; FETUS; GENE EXPRESSION; GENETIC CONSERVATION; GENETIC VARIABILITY; HIPPOCAMPUS; HUMAN; HUMAN CELL; INTRASPECIFIC VARIATION; MOLECULAR DYNAMICS; NERVE CELL DIFFERENTIATION; NONHUMAN; ONTOGENY; PATHOGENESIS; PHYLOGENY; POSTNATAL DEVELOPMENT; PREFRONTAL CORTEX; PRENATAL DEVELOPMENT; PRIORITY JOURNAL; RHESUS MONKEY; RISK FACTOR; RNA SEQUENCE; SCHIZOPHRENIA; SEQUENCE ALIGNMENT; SINGLE CELL ANALYSIS; SINGLE CELL RNA SEQUENCE; TRANSCRIPTOMICS; UPREGULATION; VALIDATION PROCESS; ANIMAL; BRAIN; EMBRYOLOGY; ENZYMOLOGY; GENE EXPRESSION REGULATION; GENETICS; GROWTH, DEVELOPMENT AND AGING; NERVOUS SYSTEM DEVELOPMENT;

MACACA MULATTA;

TRANSCRIPTOME;

ANIMALS; AUTISM SPECTRUM DISORDER; BRAIN; GENE EXPRESSION REGULATION, DEVELOPMENTAL; HUMANS; MACACA MULATTA; NEUROGENESIS; PREFRONTAL CORTEX; SCHIZOPHRENIA; TRANSCRIPTOME;

EID: 85058394301     PISSN: 00368075     EISSN: 10959203     Source Type: Journal    
DOI: 10.1126/science.aat8077     Document Type: Article

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