Gga-MIR-219b targeting BCL11B suppresses proliferation, migration and invasion of Marek's disease tumor cell MSB1

Scientific Reports

Volumn 7, Issue 1, 2017, Pages

  Zhao, Chunfang ^a   Li, Xin ^b   Han, Bo ^a   You, Zhen ^a   Qu, Lujiang ^a   Liu, Changjun ^c   Song, Jiuzhou ^d   Lian, Ling ^a   Yang, Ning ^a  

^a CHINA AGRICULTURAL UNIVERSITY   (China)

^b TIANJIN AGRICULTURAL UNIVERSITY   (China)

^c INSTITUTE OF PLANT PROTECTION   (China)

^d UNIVERSITY OF MARYLAND   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BCL11B PROTEIN, HUMAN; MICRORNA; REPRESSOR PROTEIN; TUMOR SUPPRESSOR PROTEIN;

ANIMAL; APOPTOSIS; BIRD DISEASE; CARCINOGENESIS; CELL MOTION; CELL PROLIFERATION; CHICKEN; GALLID ALPHAHERPESVIRUS 2; GENE EXPRESSION REGULATION; GENE KNOCKDOWN; GENETICS; HUMAN; MAREK DISEASE; PATHOGENICITY; PATHOLOGY; TUMOR CELL LINE; TUMOR INVASION; VIROLOGY;

ANIMALS; APOPTOSIS; CARCINOGENESIS; CELL LINE, TUMOR; CELL MOVEMENT; CELL PROLIFERATION; CHICKENS; GENE EXPRESSION REGULATION, NEOPLASTIC; GENE KNOCKDOWN TECHNIQUES; HERPESVIRUS 2, GALLID; HUMANS; MAREK DISEASE; MICRORNAS; NEOPLASM INVASIVENESS; POULTRY DISEASES; REPRESSOR PROTEINS; TUMOR SUPPRESSOR PROTEINS;

EID: 85021639015     PISSN: None     EISSN: 20452322     Source Type: Journal    
DOI: 10.1038/s41598-017-04434-w     Document Type: Article

References (57)

1. Biggs, P. M. The Leeuwenhoek Lecture, 1997. Marek's disease herpesvirus: Oncogenesis and prevention. Philos Trans R Soc Lond B Biol Sci 352, 1951-62 (1997).
2. Calnek, B. W. Pathogenesis of Marek's disease virus infection. Curr Top Microbiol Immunol 255, 25-55 (2001).
3. Burgess, S. C., et al. Marek's disease is a natural model for lymphomas overexpressing Hodgkin's disease antigen (CD30). Proc Natl Acad Sci USA 101, 13879-84 (2004).
4. Bhattacharya, S. D., et al. Micro-RNA-181a regulates osteopontin-dependent metastatic function in hepatocellular cancer cell lines. Surgery 148, 291-297 (2010).
5. Xu, H., Yao, Y., Smith, L. P., Nair, V. MicroRNA-26a-mediated regulation of interleukin-2 expression in transformed avian lymphocyte lines. Cancer cell international 10, 1 (2010).
6. Favreau, A. J., Sathyanarayana, P. miR-590-5p, miR-219-5p, miR-15b and miR-628-5p are commonly regulated by IL-3, GM-CSF and G-CSF in acute myeloid leukemia. Leuk Res 36, 334-41 (2012).
7. Bartel, D. P. MicroRNAs: Genomics, biogenesis, mechanism, function. Cell 116, 281-97 (2004).
8. Brennecke, J., Stark, A., Russell, R. B., Cohen, S. M. Principles of microRNA-target recognition. PLoS Biol 3, e85 (2005).
9. Yao, Y., et al. Differential expression of microRNAs in Marek's disease virus-transformed T-lymphoma cell lines. J Gen Virol 90, 1551-9 (2009).
10. Li, Z.-j., et al. Distinct expression pattern of miRNAs in Marek's disease virus infected-chicken splenic tumors and non-tumorous spleen tissues. Research in Veterinary Science 97, 156-161 (2014).
11. Burnside, J., et al. Deep sequencing of chicken microRNAs. BMC Genomics 9, 185 (2008).
12. Li, X., Lian, L., Zhang, D., Qu, L., Yang, N. gga-miR-26a targets NEK6 and suppresses Marek's disease lymphoma cell proliferation. Poult Sci 93, 1097-105 (2014).
13. Tian, F., Luo, J., Zhang, H., Chang, S., Song, J. MiRNA expression signatures induced by Marek's disease virus infection in chickens. Genomics 99, 152-159 (2012).
14. Lian, L., et al. Chicken gga-miR-181a targets MYBL1 and shows an inhibitory effect on proliferation of Marek's disease virustransformed lymphoid cell line. Poult Sci 94, 2616-21 (2015).
15. Han, B., et al. Chicken gga-miR-130a targets HOXA3 and MDFIC and inhibits Marek's disease lymphoma cell proliferation and migration. Mol Biol Rep 43, 667-76 (2016).
16. Han, B., et al. Chicken gga-miR-103-3p Targets CCNE1 and TFDP2 and Inhibits MDCC-MSB1 Cell Migration. G3: Genes Genomes Genetics 6, 1277-1285 (2016).
17. Burnside, J., et al. Marek's disease virus encodes MicroRNAs that map to meq and the latency-associated transcript. J Virol 80, 8778-86 (2006).
18. Zhao, Y., et al. A functional MicroRNA-155 ortholog encoded by the oncogenic Marek's disease virus. J Virol 83, 489-92 (2009).
19. Chi, J.-Q., et al. Marek's disease virus-encoded analog of microRNA-155 activates the oncogene c-Myc by targeting LTBP1 and suppressing the TGF-signaling pathway. Virology 476, 72-84 (2015).
20. Lian, L., Qu, L., Chen, Y., Lamont, S. J., Yang, N. A systematic analysis of miRNA transcriptome in Marek's disease virus-induced lymphoma reveals novel and differentially expressed miRNAs. PLoS One 7, e51003 (2012).
21. Vincent, K., Pichler, M., Lee, G. W., Ling, H. MicroRNAs, genomic instability and cancer. Int J Mol Sci 15, 14475-91 (2014).
22. Hayes, J., Peruzzi, P. P., Lawler, S. MicroRNAs in cancer: Biomarkers, functions and therapy. Trends Mol Med 20, 460-9 (2014).
23. Di Leva, G., Garofalo, M., Croce, C. M. MicroRNAs in cancer. Annu Rev Pathol 9, 287-314 (2014).
24. Friedman, J. M., Liang, G., Jones, P. A. The tumor suppressor microRNA-101 becomes an epigenetic player by targeting the polycomb group protein EZH2 in cancer. Cell cycle 8, 2313-2314 (2009).
25. Li, C., et al. MicroRNA-409-3p regulates cell proliferation and apoptosis by targeting PHF10 in gastric cancer. Cancer letters 320, 189-197 (2012).
26. Lahdaoui, F., et al. miR-219-1-3p is a negative regulator of the mucin MUC4 expression and is a tumor suppressor in pancreatic cancer. Oncogene 34, 780-788 (2015).
27. Dugas, J. C., et al. Dicer1 and miR-219 Are required for normal oligodendrocyte differentiation and myelination. Neuron 65, 597-611 (2010).
28. Huang, N., et al. MiR-219-5p inhibits hepatocellular carcinoma cell proliferation by targeting glypican-3. FEBS Lett 586, 884-91 (2012).
29. Rao, S. A., et al. miR-219-5p inhibits receptor tyrosine kinase pathway by targeting EGFR in glioblastoma. PLoS One 8, e63164 (2013).
30. Shi, F., et al. Aberrant DNA methylation of miR-219 promoter in long-term night shiftworkers. Environ Mol Mutagen 54, 406-13 (2013).
31. Gao, W., et al. Variable DNA methylation patterns associated with progression of disease in hepatocellular carcinomas. Carcinogenesis 29, 1901-1910 (2008).
32. Wang, Y., et al. Identification of differentially expressed miRNAs in chicken lung and trachea with avian influenza virus infection by a deep sequencing approach. BMC Genomics 10, 512 (2009).
33. Wakabayashi, Y., et al. Bcl11b is required for differentiation and survival of alphabeta T lymphocytes. Nat Immunol 4, 533-9 (2003).
34. Yu, Y., et al. The transcription factor Bcl11b is specifically expressed in group 2 innate lymphoid cells and is essential for their development. The Journal of Experimental Medicine 212, 865-874 (2015).
35. Cismasiu, V. B., et al. BCL11B participates in the activation of IL2 gene expression in CD4+ T lymphocytes. Blood 108, 2695-702 (2006).
36. Dubuissez, M., et al. Protein Kinase C-Mediated Phosphorylation of BCL11B at Serine 2 Negatively Regulates Its Interaction with NuRD Complexes during CD4(+) T-Cell Activation. Molecular and Cellular Biology 36, 1881-1898 (2016).
37. Grabarczyk, P., et al. Inhibition of BCL11B expression leads to apoptosis of malignant but not normal mature T cells. Oncogene 26, 3797-3810 (2007).
38. Gutierrez, A., et al. The BCL11B tumor suppressor is mutated across the major molecular subtypes of T-cell acute lymphoblastic leukemia. Blood 118, 4169-4173 (2011).
39. Huang, X., et al. Analysis of the expression pattern of the BCL11B gene and its relatives in patients with T-cell acute lymphoblastic leukemia. J Hematol Oncol 3, 44 (2010).
40. Adams, J. M., Cory, S. The Bcl-2 apoptotic switch in cancer development and therapy. Oncogene 26, 1324-37 (2007).
41. Kuribayashi, K., et al. TNFSF10 (TRAIL), a p53 target gene that mediates p53-dependent cell death. Cancer Biology & Therapy 7, 2034-2038 (2014).
42. Adams, J. M. Ways of dying: Multiple pathways to apoptosis. Genes Dev 17, 2481-95 (2003).
43. Huang, X., et al. Gene expression profiles in BCL11B-siRNA treated malignant T cells. J Hematol Oncol 4, 23 (2011).
44. Cismasiu, V. B., et al. BCL11B functionally associates with the NuRD complex in T lymphocytes to repress targeted promoter. Oncogene 24, 6753-64 (2005).
45. Topark-Ngarm, A., et al. CTIP2 associates with the NuRD complex on the promoter of p57KIP2, a newly identified CTIP2 target gene. J Biol Chem 281, 32272-83 (2006).
46. Cismasiu, V. B., et al. BCL11B is a general transcriptional repressor of the HIV-1 long terminal repeat in T lymphocytes through recruitment of the NuRD complex. Virology 380, 173-181 (2008).
47. Kalhori, V., Tornquist, K. MMP2 and MMP9 participate in S1P-induced invasion of follicular ML-1 thyroid cancer cells. Mol Cell Endocrinol 404, 113-22 (2015).
48. Jones, D., Lee, L., Liu, J. L., Kung, H. J., Tillotson, J. K. Marek disease virus encodes a basic-leucine zipper gene resembling the fos/jun oncogenes that is highly expressed in lymphoblastoid tumors. Proc Natl Acad Sci USA 89, 4042-6 (1992).
49. Levy, A. M., et al. Characterization of the Chromosomal Binding Sites and Dimerization Partners of the Viral Oncoprotein Meq in Marek's Disease Virus-Transformed T Cells. Journal of Virology 77, 12841-12851 (2003).
50. Qian, Z., Brunovskis, P., Lee, L., Vogt, P. K., Kung, H. J. Novel DNA binding specificities of a putative herpesvirus bZIP oncoprotein. J Virol 70, 7161-70 (1996).
51. Brown, A. C., et al. Homodimerization of the Meq viral oncoprotein is necessary for induction of T-cell lymphoma by Marek's disease virus. J Virol 83, 11142-51 (2009).
52. Kung, H., Tanaka, A., Nonoyama, M. 2 gene families of mareks-disease virus (mdv) with a potential role in tumor-induction in chicken (review). Int J Oncol 6, 997-1002 (1995).
53. Lian, L., et al. Gene expression analysis of host spleen responses to Marek's disease virus infection at late tumor transformation phase. Poult Sci 91, 2130-8 (2012).
54. Levy, A. M., et al. Marek's disease virus Meq transforms chicken cells via the v-Jun transcriptional cascade: A converging transforming pathway for avian oncoviruses. Proc Natl Acad Sci USA 102, 14831-6 (2005).
55. Heidari, M., Zhang, H. M., Sharif, S. Marek's disease virus induces Th-2 activity during cytolytic infection. Viral Immunol 21, 203-14 (2008).
56. Subramaniam, S., et al. Integrated analyses of genome-wide DNA occupancy and expression profiling identify key genes and pathways involved in cellular transformation by a Marek's disease virus oncoprotein, Meq. J Virol 87, 9016-29 (2013).
57. Li, X., Chiang, H.-I., Zhu, J., Dowd, S. E., Zhou, H. Characterization of a newly developed chicken 44K Agilent microarray. BMC genomics 9, 1 (2008).