Presynaptic NMDA receptors

Biology of the NMDA Receptor

Volumn , Issue , 2008, Pages 313-328

  Duguid, Ian C ^a   Smart, Trevor G ^b  

^a UNIVERSITY COLLEGE LONDON   (United Kingdom)

^b UNIVERSITY COLLEGE LONDON   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

EID: 85057918783     PISSN: None     EISSN: None     Source Type: Book    
DOI: None     Document Type: Chapter

References (121)

1. Akaike, N. and Moorhouse, A.J., Techniques: applications of the nerve-bouton preparation in neuropharmacology, Trends Pharmacol. Sci., 24, 44, 2003.
2. Al Hallaq, R.A. et al., Association of NR3A with the N-methyl-D-aspartate receptor NR1 and NR2 subunits, Mol. Pharmacol., 62, 1119, 2002.
3. Anderson, C.M. and Swanson, R.A., Astrocyte glutamate transport: review of properties, regulation, and physiological functions, Glia, 32, 1, 2000.
4. Aoki, C. et al., Cellular and subcellular localization of NMDA-R1 subunit immunore-activity in the visual cortex of adult and neonatal rats, J. Neurosci., 14, 5202, 1994.
5. Araque, A., Carmignoto, G., and Haydon, P.G., Dynamic signaling between astrocytes and neurons, Annu. Rev. Physiol., 63, 795, 2001.
6. Araque, A. et al., Calcium elevation in astrocytes causes an NMDAR-dependent increase in the frequency of miniature synaptic currents in cultured hippocampal neurons, J. Neurosci., 18, 6822, 1998.
7. Auger, C. and Attwell, D., Fast removal of synaptic glutamate by postsynaptic transporters, Neuron, 28, 547, 2000.
8. Bardoni, R. et al., Presynaptic NMDARs modulate glutamate release from primary sensory neurons in rat spinal cord dorsal horn, J. Neurosci., 24, 2774, 2004.
9. Bender, V.A. et al., Two coincidence detectors for spike timing-dependent plasticity in somatosensory cortex, J. Neurosci., 26, 4166, 2006.
10. Berberich, S. et al., Lack of NMDAR subtype selectivity for hippocampal long-term potentiation, J. Neurosci., 25, 6907, 2005.
11. Berretta, N. and Jones, R.S., Tonic facilitation of glutamate release by presynaptic N-methyl-D-aspartate autoreceptors in the entorhinal cortex, Neuroscience, 75, 339, 1996.
12. Bezzi, P. and Volterra, A., A neuron-glia signaling network in the active brain, Curr. Opin. Neurobiol., 11, 387, 2001.
13. Bliss, TV., Collingridge, G.L., and Morris, R.G., Introduction. Long-term potentiation and structure of the issue, Philos. Trans. R. Soc. Lond. B. Biol. Sci., 358, 607, 2003.
14. Brodin, L., Christenson, J., and Grillner, S., Single sensory neurons activate excitatory amino acid receptors in the lamprey spinal cord, Neurosci. Lett., 75, 75, 1987.
15. Buchanan, J.T., Identification of interneurons with contralateral, caudal axons in the lamprey spinal cord: synaptic interactions and morphology, J. Neurophysiol., 47, 961, 1982.
16. Buchanan, J.T. et al., Reticulospinal neurones activate excitatory amino acid receptors, Brain Res., 408, 321, 1987.
17. Buchanan, J.T. and Grillner, S., Newly identified “glutamate interneurons” and their role in locomotion in the lamprey spinal cord, Science, 236, 312, 1987.
18. Bustos, G. et al., Regulation of excitatory amino acid release by N-methyl-D-aspartate receptors in rat striatum: in vivo microdialysis studies, Brain Res., 585, 105, 1992.
19. Casado, M., Dieudonne, S., and Ascher, P., Presynaptic N-methyl-D-aspartate receptors at the parallel fiber-Purkinje cell synapse, Proc. Natl. Acad. Sci. USA, 97, 11593, 2000.
20. Casado, M., Isope, P., and Ascher, P., Involvement of presynaptic N-methyl-D-aspartate receptors in cerebellar long-term depression, Neuron, 33, 123, 2002.
21. Chadderton, P., Margrie, T.W., and Hausser, M., Integration of quanta in cerebellar granule cells during sensory processing, Nature, 428, 856, 2004.
22. Chazot, P.L. et al., Molecular characterization of N-methyl-D-aspartate receptors expressed in mammalian cells yields evidence for the coexistence of three subunit types within a discrete receptor molecule, J. Biol. Chem., 269, 24403, 1994.
23. Cincotta, M. et al., Bidirectional transport of NMDAR and ionophore in the vagus nerve, Eur. J. Pharmacol., 160, 167, 1989.
24. Cochilla, A.J. and Alford, S., Glutamate receptor-mediated synaptic excitation in axons of the lamprey, J. Physiol., 499 (Pt 2), 443, 1997.
25. Cochilla, A.J. and Alford, S., NMDAR-mediated control of presynaptic calcium and neurotransmitter release, J. Neurosci., 19, 193, 1999.
26. Cull-Candy, S., Brickley, S., and Farrant, M., NMDAR subunits: diversity, development and disease, Curr. Opin. Neurobiol., 11, 327, 2001.
27. Danysz, W. and Parsons, A.C., Glycine and N-methyl-D-aspartate receptors: physiological significance and possible therapeutic applications, Pharmacol. Rev., 50, 597, 1998.
28. Das, S. et al., Increased NMDA current and spine density in mice lacking the NMDAR subunit NR3A, Nature, 393, 377, 1998.
29. DeBiasi, S. et al., Presynaptic NMDARs in the neocortex are both auto- and heteroreceptors, Neuroreport, 7, 2773, 1996.
30. Dudel, J. and Kuffler, S.W., Presynaptic inhibition at the crayfish neuromuscular junction, J. Physiol., 155, 543, 1961.
31. Duguid, I.C. et al., Somatodendritic release of glutamate regulates synaptic inhibition in cerebellar Purkinje cells via autocrine mGluR1 activation, J. Neurosci., 27, 12464, 2007.
32. Duguid, I.C. and Smart, T.G., Retrograde activation of presynaptic NMDARs enhances GABA release at cerebellar interneuron-Purkinje cell synapses, Nat. Neurosci., 7, 525, 2004.
33. Eccles, J.C., Presynaptic inhibition in the spinal cord, Prog. Brain Res., 12, 65, 1964.
34. Eccles, J.C., Schmidt, R., and Willis, W.D., Pharmacological studies on presynaptic inhibition, J. Physiol., 168, 500, 1963.
35. Farb, C.R., Aoki, C., and Ledoux, J.E., Differential localization of NMDA and AMPA receptor subunits in the lateral and basal nuclei of the amygdala: a light and electron microscopic study, J. Comp. Neurol., 362, 86, 1995.
36. Feng, B. et al., Structure-activity analysis of a novel NR2C/NR2D-preferring NMDAR antagonist: 1-(phenanthrene-2-carbonyl) piperazine-2,3-dicarboxylic acid, Br. J. Pharmacol., 141, 508, 2004.
37. Fink, K., Bonisch, H., and Gothert, M., Presynaptic NMDARs stimulate noradrenaline release in the cerebral cortex, Eur. J. Pharmacol., 185, 115, 1990.
38. Fischer, G. et al., Ro 25-6981, a highly potent and selective blocker of N-methyl-D-aspartate receptors containing the NR2B subunit. Characterization in vitro, J. Pharmacol. Exp. Ther., 283, 1285, 1997.
39. Fiszman, M.L. et al., NMDARs increase the size of GABAergic terminals and enhance GABA release, J. Neurosci., 25, 2024, 2005.
40. Gibbs, T.T., Russek, S.J., and Farb, D.H., Sulfated steroids as endogenous neuromodulators, Pharmacol. Biochem. Behav., 84, 555, 2006.
41. Glitsch, M. and Marty, A., Presynaptic effects of NMDA in cerebellar Purkinje cells and interneurons, J. Neurosci., 19, 511, 1999.
42. Gracy, K.N. and Pickel, V.M., Ultrastructural immunocytochemical localization of the N-methyl-D-aspartate receptor and tyrosine hydroxylase in the shell of the rat nucleus accumbens, Brain Res., 739, 169, 1996.
43. Hamada, T. et al., NMDA induced glutamate release from the suprachiasmatic nucleus: an in vitro study in the rat, Neurosci. Lett., 256, 93, 1998.
44. Hatton, C.J. and Paoletti, P., Modulation of triheteromeric NMDARs by N-terminal domain ligands, Neuron, 46, 261, 2005.
45. Herkert, M., Rottger, S., and Becker, C.M., The NMDAR subunit NR2B of neonatal rat brain: complex formation and enrichment in axonal growth cones, Eur. J. Neurosci., 10, 1553, 1998.
46. Huang, H. and Bordey, A., Glial glutamate transporters limit spillover activation of presynaptic NMDARs and influence synaptic inhibition of Purkinje neurons, J. Neurosci., 24, 5659, 2004.
47. Humeau, Y. et al., Presynaptic induction of heterosynaptic associative plasticity in the mammalian brain, Nature, 426, 841, 2003.
48. Ito, M., Cerebellar long-term depression: characterization, signal transduction, and functional roles, Physiol. Rev., 81, 1143, 2001.
49. Ito, M., The molecular organization of cerebellar long-term depression, Nat. Rev. Neurosci., 3, 896, 2002.
50. Johnson, K.M. and Jeng, Y.J., Pharmacological evidence for N-methyl-D-aspartate receptors on nigrostriatal dopaminergic nerve terminals, Can. J. Physiol. Pharmacol., 69, 1416, 1991.
51. Jourdain, P. et al., Glutamate exocytosis from astrocytes controls synaptic strength, Nat. Neurosci., 10, 331, 2007.
52. Kandel, E.R. and Schwartz, J.H., Molecular biology of learning: modulation of transmitter release, Science, 218, 433, 1982.
53. Khakh, B.S. and Henderson, G., Modulation of fast synaptic transmission by presynaptic ligand-gated cation channels, J. Auton. Nerv. Syst., 81, 110, 2000.
54. Kimoto, T. et al., Neurosteroid synthesis by cytochrome p450-containing systems localized in the rat brain hippocampal neurons: N-methyl-D-aspartate and calcium-dependent synthesis, Endocrinology, 142, 3578, 2001.
55. Kirischuk, S., Clements, J.D., and Grantyn, R., Presynaptic and postsynaptic mechanisms underlie paired pulse depression at single GABAergic boutons in rat collicular cultures, J. Physiol., 543, 99, 2002.
56. Krebs, M.O. et al., Glutamatergic control of dopamine release in the rat striatum: evidence for presynaptic N-methyl-D-aspartate receptors on dopaminergic nerve terminals, J. Neurochem., 56, 81, 1991.
57. Kullmann, D.M. and Asztely, F., Extrasynaptic glutamate spillover in the hippocampus: evidence and implications, Trends Neurosci., 21, 8, 1998.
58. Langer, S.Z., Presynaptic autoreceptors regulating transmitter release, Neurochem. Inc., 52, 26, 2008.
59. Lev-Ram, V. et al., Synergies and coincidence requirements between NO, cGMP, and Ca2+ in the induction of cerebellar long-term depression, Neuron, 18, 1025, 1997.
60. Levenes, C., Daniel, H., and Crepel, F., Retrograde modulation of transmitter release by postsynaptic subtype 1 metabotropic glutamate receptors in the rat cerebellum, J. Physiol., 537, 125, 2001.
61. Lien, C.C. et al., Visual stimuli-induced LTD of GABAergic synapses mediated by presynaptic NMDARs, Nat. Neurosci., 9, 372, 2006.
62. Liu, H. et al., Evidence for presynaptic N-methyl-D-aspartate autoreceptors in the spinal cord dorsal horn, Proc. Natl. Acad. Sci. USA, 91, 8383, 1994.
63. Liu, L. et al., Role of NMDAR subtypes in governing the direction of hippocampal synaptic plasticity, Science, 304, 1021, 2004.
64. Liu, S.J. and Lachamp, P., The activation of excitatory glutamate receptors evokes a long-lasting increase in the release of GABA from cerebellar stellate cells, J. Neurosci., 26, 9332, 2006.
65. Ludwig, M. and Pittman, Q.J., Talking back: dendritic neurotransmitter release, Trends Neurosci., 26, 255, 2003.
66. Luscher, C. et al., Synaptic plasticity and dynamic modulation of the postsynaptic membrane, Nat. Neurosci., 3, 545, 2000.
67. MacDermott, A.B., Role, L.W., and Siegelbaum, S.A., Presynaptic ionotropic receptors and the control of transmitter release, Annu. Rev. Neurosci., 22, 443, 1999.
68. Malayev, A., Gibbs, T.T., and Farb, D.H., Inhibition of the NMDA response by pregnenolone sulphate reveals subtype selective modulation of NMDARs by sulphated steroids, Br. J. Pharmacol., 135, 901, 2002.
69. Mameli, M. et al., Neurosteroid-induced plasticity of immature synapses via retrograde modulation of presynaptic NMDARs, J. Neurosci., 25, 2285, 2005.
70. Marcaggi, P. and Attwell, D., Short- and long-term depression of rat cerebellar parallel fibre synaptic transmission mediated by synaptic crosstalk, J. Physiol., 578, 545, 2007.
71. Martin, D. et al., Autoreceptor regulation of glutamate and aspartate release from slices of the hippocampal CA1 area, J. Neurochem., 56, 1647, 1991.
72. Mayer, M.L. and Armstrong, N., Structure and function of glutamate receptor ion channels, Annu. Rev. Physiol., 66, 161, 2004.
73. McBain, C.J. and Mayer, M.L., N-methyl-D-aspartic acid receptor structure and function, Physiol. Rev., 74, 723, 1994.
74. Mellon, S.H. and Vaudry, H., Biosynthesis of neurosteroids and regulation of their synthesis, Int. Rev. Neurobiol., 46, 33, 2001.
75. Mott, D.D. et al., Phenylethanolamines inhibit NMDARs by enhancing proton inhibition, Nat. Neurosci., 1, 659, 1998.
76. Okabe, S. et al., Hippocampal synaptic plasticity in mice overexpressing an embryonic subunit of the NMDAR, J. Neurosci., 18, 4177, 1998.
77. Ozawa, S., Role of glutamate transporters in excitatory synapses in cerebellar Purkinje cells, Brain Nerve, 59, 669, 2007.
78. Ozawa, S., Kamiya, H., and Tsuzuki, K., Glutamate receptors in the mammalian central nervous system, Prog. Neurobiol., 54, 581, 1998.
79. Paoletti, P., Ascher, P., and Neyton, J., High-affinity zinc inhibition of NMDA NR1-NR2A receptors, J. Neurosci., 17, 5711, 1997.
80. Paoletti, P. and Neyton, J., NMDAR subunits: function and pharmacology, Curr. Opin. Pharmacol., 7, 39, 2007.
81. Paquet, M. and Smith, Y., Presynaptic NMDAR subunit immunoreactivity in GAB-Aergic terminals in rat brain, J. Comp. Neurol., 423, 330, 2000.
82. Petralia, R.S., Wang, Y.X., and Wenthold, R.J., The NMDAR subunits NR2A and NR2B show histological and ultrastructural localization patterns similar to those of NR1, J. Neurosci., 14, 6102, 1994.
83. Petralia, R.S., Yokotani, N., and Wenthold, R.J., Light and electron microscope distribution of the NMDAR subunit NMDAR1 in the rat nervous system using a selective anti-peptide antibody, J. Neurosci., 14, 667, 1994.
84. Pina-Crespo, J.C. and Gibb, A.J., Subtypes of NMDARs in new-born rat hippocampal granule cells, J. Physiol., 541, 41, 2002.
85. Piochon, C. et al., NMDAR contribution to the climbing fiber response in the adult mouse Purkinje cell, J. Neurosci., 27, 10797, 2007.
86. Pittaluga, A. and Raiteri, M., N-methyl-D-aspartic acid (NMDA) and non-NMDARs regulating hippocampal norepinephrine release. I. Location on axon terminals and pharmacological characterization, J. Pharmacol. Exp. Ther., 260, 232, 1992.
87. Quinlan, E.M. et al., Rapid, experience-dependent expression of synaptic NMDARs in visual cortex in vivo, Nat. Neurosci., 2, 352, 1999.
88. Rachline, J. et al., The micromolar zinc-binding domain on the NMDAR subunit NR2B, J. Neurosci., 25, 308, 2005.
89. Raditsch, M. et al., Subunit-specific block of cloned NMDARs by argiotoxin-636, FEBS Lett, 324, 63, 1993.
90. Raiteri, M., Functional pharmacology in human brain, Pharmacol. Rev., 58, 162, 2006.
91. Renzi, M., Farrant, M., and Cull-Candy, S.G., Climbing-fibre activation of NMDARs in Purkinje cells of adult mice, J. Physiol., 585, 91, 2007.
92. Robert, A., Black, J.A., and Waxman, S.G., Endogenous NMDA-receptor activation regulates glutamate release in cultured spinal neurons, J. Neurophysiol., 80, 196, 1998.
93. Sasaki, Y.F. et al., Characterization and comparison of the NR3A subunit of the NMDAR in recombinant systems and primary cortical neurons, J. Neurophysiol., 87, 2052, 2002.
94. Schlicker, E. and Kathmann, M., Modulation of transmitter release via presynaptic cannabinoid receptors, Trends Pharmacol. Sci., 22, 565, 2001.
95. Shigeri, Y. et al., Effects of threo-beta-hydroxyaspartate derivatives on excitatory amino acid transporters (EAAT4 and EAAT5), J. Neurochem., 79, 297, 2001.
96. Shimamoto, K. et al., DL-threo-beta-benzyloxyaspartate, a potent blocker of excitatory amino acid transporters, Mol. Pharmacol., 53, 195, 1998.
97. Shin, J.H. and Linden, D.J., An NMDAR/nitric oxide cascade is involved in cerebellar LTD but is not localized to the parallel fiber terminal, J. Neurophysiol., 94, 4281, 2005.
98. Siegel, S.J. et al., Regional, cellular, and ultrastructural distribution of N-methyl-D-aspartate receptor subunit 1 in monkey hippocampus, Proc. Natl. Acad. Sci. USA, 91, 564, 1994.
99. Sjostrom, PJ., Turrigiano, G.G., and Nelson, S.B., Neocortical LTD via coincident activation of presynaptic NMDA and cannabinoid receptors, Neuron, 39, 641, 2003.
100. 2+ ions: modulators of excitatory and inhibitory synaptic activity, Neuroscientist, 10, 432, 2004.
101. Smart, T.G., Xie, X., and Krishek, B.J., Modulation of inhibitory and excitatory amino acid receptor ion channels by zinc, Prog. Neurobiol., 42, 393, 1994.
102. Stevens, C.F., Neurotransmitter release at central synapses, Neuron, 40, 381, 2003.
103. Stevens, C.F., Presynaptic function, Curr. Opin. Neurobiol., 14, 341, 2004.
104. Suarez, L.M. and Solis, J.M., Taurine potentiates presynaptic NMDARs in hippocampal Schaffer collateral axons, Eur. J. Neurosci, 24, 405, 2006.
105. Sudhof, T.C., The synaptic vesicle cycle, Annu. Rev. Neurosci., 27, 509, 2004.
106. Tovar, K.R. and Westbrook, G.L., The incorporation of NMDARs with a distinct subunit composition at nascent hippocampal synapses in vitro, J. Neurosci., 19, 4180, 1999.
107. Traynelis, S.F. et al., Control of voltage-independent zinc inhibition of NMDARs by the NR1 subunit, J. Neurosci., 18, 6163, 1998.
108. Tzingounis, A.V. and Wadiche, J.I., Glutamate transporters: confining runaway excitation by shaping synaptic transmission, Nat. Rev. Neurosci., 8, 935, 2007.
109. Vesselkin, N.P. et al., Ultrastructural study of glutamate- and GABA-immunoreac-tive terminals contacting the primary afferent fibers in frog spinal cord. A double postembedding immunocytochemical study, Brain Res., 960, 267, 2003.
110. Vorobjev, V.S., Vibrodissociation of sliced mammalian nervous tissue, J. Neurosci. Meth., 38, 145, 1991.
111. Wang, H. and Pickel, V.M., Presence of NMDA-type glutamate receptors in cingulate corticostriatal terminals and their postsynaptic targets, Synapse, 35, 300, 2000.
112. Wang, J.K., Presynaptic glutamate receptors modulate dopamine release from striatal synaptosomes, J. Neurochem., 57, 819, 1991.
113. Wenzel, A. et al., N-methyl-D-aspartate receptors containing the NR2D subunit in the retina are selectively expressed in rod bipolar cells, Neuroscience, 78, 1105, 1997.
114. Wenzel, A. et al., Distribution of NMDAR subunit proteins NR2A, 2B, 2C and 2D in rat brain, NeuroReport, 7, 45, 1995.
115. Wenzel, A. et al., Developmental and regional expression of NMDAR subtypes containing the NR2D subunit in rat brain, J. Neurochem., 66, 1240, 1996.
116. Williams, K., Ifenprodil discriminates subtypes of N-methyl-D-aspartate receptor: selectivity and mechanisms at recombinant heteromeric receptors, Mol. Pharmacol., 44, 851, 1993.
117. Woodhall, G. et al., NR2B-containing NMDA autoreceptors at synapses on entorhi-nal cortical neurons, J. Neurophysiol., 86, 1644, 2001.
118. Yamakura, T. et al., Different sensitivities of NMDAR channel subtypes to non-competitive antagonists, NeuroReport, 4, 687, 1993.
119. Yamakura, T. and Shimoji, K., Subunit- and site-specific pharmacology of the NMDAR channel, Prog. Neurobiol., 59, 279, 1999.
120. Yang, J., Woodhall, G.L., and Jones, R.S., Tonic facilitation of glutamate release by presynaptic NR2B-containing NMDARs is increased in the entorhinal cortex of chronically epileptic rats, J. Neurosci., 26, 406, 2006.
121. Zilberter, Y., Dendritic release of glutamate suppresses synaptic inhibition of pyramidal neurons in rat neocortex, J. Physiol., 528, 489, 2000.