Butyrate producers as potential next-generation probiotics: Safety assessment of the administration of Butyricicoccus pullicaecorum to healthy volunteers

mSystems

Volumn 3, Issue 6, 2018, Pages

  Boesmans, Leen ^a   Valles Colomer, Mireia ^b,c   Wang, Jun ^b,c   Eeckhaut, Venessa ^d   Falony, Gwen ^b,c   Ducatelle, Richard ^d   Van Immerseel, Filip ^d   Raes, Jeroen ^b,c,e   Verbeke, Kristin ^a,f  

^a UNIVERSITY OF LEUVEN   (Belgium)

^b REGA INSTITUTE FOR MEDICAL RESEARCH   (Belgium)

^c DEPARTMENT OF PLANT SYSTEMS BIOLOGY   (Belgium)

^d GHENT UNIVERSITY   (Belgium)

^e VRIJE UNIVERSITEIT BRUSSEL   (Belgium)

^f LEUVEN FOOD SCIENCE AND NUTRITION RESEARCH CENTRE LFORCE   (Belgium)

Author keywords

Butyricicoccus pullicaecorum; Metabolome; Microbiome; Next generation probiotic; Safety; Tolerance

Indexed keywords

BUTYRIC ACID; MALTODEXTRIN; PLACEBO; PROBIOTIC AGENT;

ABDOMINAL PAIN; ADULT; ARTHRALGIA; ARTICLE; BACTERIAL METABOLISM; BUTYRICICOCCUS PULLICAECORUM; CLOSTRIDIUM; CONTROLLED STUDY; CROSSOVER PROCEDURE; DIARRHEA; DOUBLE BLIND PROCEDURE; DRUG SAFETY; DRUG TOLERABILITY; ENTEROCOLITIS; EXPLORATORY RESEARCH; FEMALE; GASTRITIS; HUMAN; HUMAN EXPERIMENT; IN VITRO STUDY; INTESTINE FLORA; LOOSE FECES; MALE; NORMAL HUMAN; PHASE 1 CLINICAL TRIAL; RANDOMIZED CONTROLLED TRIAL; RISK ASSESSMENT;

EID: 85056707729     PISSN: None     EISSN: 23795077     Source Type: Journal    
DOI: 10.1128/mSystems.00094-18     Document Type: Article

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